Автор: Neal Michael J. Название: Medical Pharmacology at a Glance, 9 ed ISBN: 1119548012 ISBN-13(EAN): 9781119548010 Издательство: Wiley Рейтинг: Цена: 24350.00 T Наличие на складе: Есть Описание: The internationally best-selling Medical Pharmacology at a Glance is the ideal companion for all medical and healthcare students, providing a visual overview of pharmacology, and describing the basic principles of drug action, interaction, absorption, and excretion. Clear and accessible chapters organised around common diseases and conditions facilitate efficient clinical learning, and include references to drug classes and side effects, disease pathophysiology, prescribing guidelines, and more. Now in its ninth edition, this leading guide has been thoroughly updated to reflect current guidelines and drug information.
This edition features new and revised illustrations, additional pedagogical tools, and enhanced online content. Widely recognised as both the best introduction to medical pharmacology and the perfect revision tool for USMLE and pharmacology exams, this invaluable guide: Covers a wide range of drugs used to treat conditions such as hypertension, anaemias, cancer, and affective disordersExplains drug mechanisms and the principles of drug actionDiscusses practical topics including drug misuse, drug indications, and side effectsIncludes a companion website featuring online cases, flashcards, and a list of core drugs
Автор: Brown M.J. et al. Название: Clinical Pharmacology, 12 ed. IE ISBN: 0702073296 ISBN-13(EAN): 9780702073298 Издательство: Elsevier Science Рейтинг: Цена: 38310.00 T Наличие на складе: Поставка под заказ. Описание:
'The very last thing a drug regulator wishes to be able to say is, like Lord Byron (1788-1824), on the publication of his poem Childe Harold's Pilgrimage, 'I awoke one morning and found myself famous.'
The twelfth edition of this long-established textbook of clinical pharmacology (first published in 1960) continues its fine tradition of balancing science and practice for improved evidence-based drug therapy and good prescribing in therapeutic settings increasingly complicated by intercurrent disease and polypharmacy.
Автор: Reid Название: Lecture Notes: Clinical Pharmacology & Therapeutics. 2006. IE ISBN: 1405135190 ISBN-13(EAN): 9781405135191 Издательство: Wiley Рейтинг: Цена: 20050.00 T Наличие на складе: Есть Описание: Lecture Notes: Clinical Pharmacology & Therapeutics is the core text for medical students, junior doctors, students in nursing, dentistry and pharmacy, general practitioners and allied health professionals who want a concise introduction to the subject of clinical pharmacology and the latest information on new and withdrawn drugs.
Автор: Katja Strohfeldt-Venables Название: Essentials of Inorganic Chemistry: For Students of Pharmacy, Pharmaceutical Sciences and Medicinal Chemistry.- Wiley, 2015 ISBN: 0470665580 ISBN-13(EAN): 9780470665589 Издательство: Wiley Рейтинг: Цена: 49580.00 T Наличие на складе: Поставка под заказ. Описание: A comprehensive introduction to inorganic chemistry and, specifically, the science of metal-based drugs, Essentials of Inorganic Chemistry describes the basics of inorganic chemistry, including organometallic chemistry and radiochemistry, from a pharmaceutical perspective.
Автор: Kimko Hui Название: Simulation For Designing Clinical Trials: A Pharmacokinetic-Pharmacodynamic Modeling Perspective ISBN: 0824708628 ISBN-13(EAN): 9780824708627 Издательство: Taylor&Francis Рейтинг: Цена: 183750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of modern clinical trial simulation, this book supplies a rigorous framework for employing simulation as an experiment, according to a predefined simulation plan, that reflects good simulation practices. The book discusses how to design clinical trials according to their probability for success, techniques to define distributions of virtual subjects' characteristics, methods to determine the sensitivity of the trial design, and the population relationship between dosing schedules and patient response.
Автор: Chang, Mark Название: Monte Carlo Simulation for the Pharmaceutical Industry ISBN: 1138374385 ISBN-13(EAN): 9781138374386 Издательство: Taylor&Francis Рейтинг: Цена: 65320.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Helping you become a creative, logical thinker and skillful simulator, Monte Carlo Simulation for the Pharmaceutical Industry: Concepts, Algorithms, and Case Studies provides broad coverage of the entire drug development process, from drug discovery to preclinical and clinical trial aspects to commercialization. It presents the theories and methods needed to carry out computer simulations efficiently, covers both descriptive and pseudocode algorithms that provide the basis for implementation of the simulation methods, and illustrates real-world problems through case studies.
The text first emphasizes the importance of analogy and simulation using examples from a variety of areas, before introducing general sampling methods and the different stages of drug development. It then focuses on simulation approaches based on game theory and the Markov decision process, simulations in classical and adaptive trials, and various challenges in clinical trial management and execution. The author goes on to cover prescription drug marketing strategies and brand planning, molecular design and simulation, computational systems biology and biological pathway simulation with Petri nets, and physiologically based pharmacokinetic modeling and pharmacodynamic models. The final chapter explores Monte Carlo computing techniques for statistical inference.
This book offers a systematic treatment of computer simulation in drug development. It not only deals with the principles and methods of Monte Carlo simulation, but also the applications in drug development, such as statistical trial monitoring, prescription drug marketing, and molecular docking.
Автор: Joseph Goldberg, Stephen Stahl Название: Practical Psychopharmacology : Translating Findings From Evidence-Based Trials into Real-World Clinical Practice ISBN: 1108450741 ISBN-13(EAN): 9781108450744 Издательство: Cambridge Academ Рейтинг: Цена: 63360.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: An accessible book for clinicians at all levels of training and experience who prescribe psychiatric medications and wish to better understand the rationale and empirical evidence base behind choosing treatments optimally tailored to the needs of individual patients.
Автор: John O`Quigley, Alexia Iasonos, Bjorn Bornkamp Название: Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials ISBN: 0367330687 ISBN-13(EAN): 9780367330682 Издательство: Taylor&Francis Рейтинг: Цена: 76550.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This handbook provides an overview of up-to-date statistical methods required for design, monitoring and analysis for dose finding clinical trials, focusing both on the clinical aspects as well as statistical considerations. This book will not cover statistical methods for Phase II non-dose finding studies or Phase III clinical trials.
Accurate sample size calculation ensures that clinical studies have adequate power to detect clinically meaningful effects. This results in the efficient use of resources and avoids exposing a disproportionate number of patients to experimental treatments caused by an overpowered study.
Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research explains how to determine sample size for studies with correlated outcomes, which are widely implemented in medical, epidemiological, and behavioral studies.
The book focuses on issues specific to the two types of correlated outcomes: longitudinal and clustered. For clustered studies, the authors provide sample size formulas that accommodate variable cluster sizes and within-cluster correlation. For longitudinal studies, they present sample size formulas to account for within-subject correlation among repeated measurements and various missing data patterns. For multiple levels of clustering, the level at which to perform randomization actually becomes a design parameter. The authors show how this can greatly impact trial administration, analysis, and sample size requirement.
Addressing the overarching theme of sample size determination for correlated outcomes, this book provides a useful resource for biostatisticians, clinical investigators, epidemiologists, and social scientists whose research involves trials with correlated outcomes. Each chapter is self-contained so readers can explore topics relevant to their research projects without having to refer to other chapters.
Автор: Katzung Название: Basic and Clinical Pharmacology. 13 ed IE ISBN: 1259252906 ISBN-13(EAN): 9781259252907 Издательство: McGraw-Hill Рейтинг: Цена: 37180.00 T Наличие на складе: Невозможна поставка. Описание: The most up-to-date, comprehensive, and authoritative pharmacology text in health medicineOrganized to reflect the syllabi in many pharmacology courses and in integrated curricula, Basic & Clinical Pharmacology, 13e covers the important concepts students need to know about the science of pharmacology and its application to clinical practice.
Название: Clinical trials handbook ISBN: 0471213888 ISBN-13(EAN): 9780471213888 Издательство: Wiley Рейтинг: Цена: 226990.00 T Наличие на складе: Поставка под заказ. Описание: Provides a comprehensive and thorough reference on the basics and practices of clinical trials Includes chapters on hot topics like: adverse event reporting (AER) systems, adaptive trial designs, and crossover trial designs Presents chapters on issues for specific disease areas: cardiology, oncology, cognitive, dermatology, etc.
Автор: David Harrington Название: Designs for Clinical Trials ISBN: 1461429536 ISBN-13(EAN): 9781461429531 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book examines current issues and controversies in the design of clinical trials, including topics in adaptive and sequential designs, the design of correlative genomic studies, the design of studies in which missing data is anticipated.
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