Producing Biomolecular Substances with Fermenters, Bioreactors, and Biomolecular Synthesizers, Hochfeld, William L.

Автор: Dieter Eibl; Regine Eibl
Название: Disposable Bioreactors II
ISBN: 3662510758 ISBN-13(EAN): 9783662510759
Издательство: Springer
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Цена: 174130.00 T
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Описание: This book covers all aspects of this interdisciplinary technology, where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science.

Автор: Rusling, James F.
Название: Biomolecular Films
ISBN: 0824708997 ISBN-13(EAN): 9780824708993
Издательство: Taylor&Francis
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Цена: 306240.00 T
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Автор: Fernandez Stigliano, Ariel
Название: Biomolecular interfaces
ISBN: 3319168495 ISBN-13(EAN): 9783319168494
Издательство: Springer
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Цена: 69870.00 T
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Описание:

The Aqueous Interface of a Soluble Protein or the Birth of Epistructural Biology.- Electrostatic Exploration of Biomolecular Interfaces: The Chemical Function of Interfacial Water.- Semiempirical Solution to the Protein Folding Problem Through a Combination of Structural and Epistructural Approaches.- Packing Defects and Protein Hydration: Dynamics of the Aqueous Interface.- Proteins in the Order-Disorder Twilight: Unstable Interfaces Promote Protein Aggregation.- Evolution of Protein Structure Degradation and Lessons for the Drug Designer.- Chemical Functionality of the Aqueous Interface in Soluble Proteins.- The Biomolecular Interface as a Selectivity Filter for Drug-Based Targeted Therapy.- Wrapping-Based Re-Engineering of an Anticancer Drug to Make it Safer.- Biomolecular Interfaces Provide Universal Markers for Drug Specificity and Personalized Medicine.- Controlling Induced Folding Through Wrapping Drug Design.- Wrapping Drug Combinations for Therapeutic Editing of Side Effects: Systems Biology Meets Wrapping Technology.- Multi-Target Control of Drug Impact: A Therapeutic Imperative in Cancer Systems Biology.- Engineering Therapeutic Alignments between Immune Response and Molecularly Targeted Cancer Treatment.- High-Level Quantum Chemistry Empowers the Wrapping Technology for Drug Design.- Epilogue.- Appendix 1. Code for Dehydron Identification.- Appendix 2. Solutions of Problems.

Автор: Rashid Bashir; Mauro Ferrari; Steven T. Wereley
Название: BioMEMS and Biomedical Nanotechnology
ISBN: 1489977430 ISBN-13(EAN): 9781489977434
Издательство: Springer
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Цена: 148010.00 T
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Описание: Part I. Micro and Nanoscale Biosensors and Materials: Biosensors and Biochips.- Cantilever Assays: A Universal Platform for Multi-plexed Label-Free Bioassays.- An On-chip Artificial Pore For Molecular Sensing.- Cell Based Chemical Sensing Technologies.- Fabrication issues of Biomedical Micro Devices.- Intelligent Polymeric Networks in Biomolecular Sensing.- Part II Processing and Integrated Systems: A Multi-Functional Micro Total Analysis System ( TAS) Platform for Transport and Sensing of Biological Fluids using Microchannel Parallel Electrodes.- Dielectrophoretic Traps for Cell Manipulation.- BioMEMS for Cellular Manipulation and Analysis.- Implantable Wireless Microsystems.- Microfluidic Tectonics: An integrated organic autonomous platform.- AC Electrokinetic Stirring and Focusing of Nanoparticles.- Part III. Micro-fluidics and Characterization: Particle Dynamics in a Dielectrophoretic Microdevice.- Microfluidics Simulations I.- Modeling Electroosmotic Flow in Nanochannels.- Nano-Particle Image Velocimetry: A Near-Wall Velocimetry Technique with Submicron Spatial Resolution.- Optical MEMS-Based Sensor Development with Applications to Microfluidics.- Vascular Cell Responses to Fluid Shear Stress.

Автор: Fern?ndez
Название: Physics at the Biomolecular Interface
ISBN: 3319308513 ISBN-13(EAN): 9783319308517
Издательство: Springer
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Цена: 139310.00 T
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Описание: This bookfocuses primarily on the role of interfacial forces in understanding biologicalphenomena at the molecular scale. By providing a suitable statisticalmechanical apparatus to handle the biomolecular interface, the book becomesuniquely positioned to address core problems in molecular biophysics. Ithighlights the importance of interfacial tension in delineating a solution tothe protein folding problem, in unravelling the physico-chemical basis ofenzyme catalysis and protein associations, and in rationally designingmolecular targeted therapies. Thus grounded in fundamental science, the bookdevelops a powerful technological platform for drug discovery, while it is setto inspire scientists at any level in their careers determined to address themajor challenges in molecular biophysics.Theacknowledgment of how exquisitely the structure and dynamics of proteins and theiraqueous environment are related attests to the overdue recognition thatbiomolecular phenomena cannot be effectively understood without dealing withinterfacial behaviour. There is an urge to grasp how biologically relevantbehaviour is shaped by the structuring of biomolecular interfaces and howinterfacial tension affects the molecular events that take place in the cell.This book squarely addresses these needs from a physicist perspective.Thebook may serve as a monograph for practitioners and, alternatively, as anadvanced textbook. Fruitful reading requires a background in physical chemistryand some basics in biophysics. The selected problems at the end of the chaptersand the progression in conceptual difficulty make it a suitable textbook for agraduate level course or an elective course for seniors majoring in chemistry,physics, biomedical engineering or related disciplines.

Автор: C. Nicolini
Название: From Neural Networks and Biomolecular Engineering to Bioelectronics
ISBN: 1489910905 ISBN-13(EAN): 9781489910905
Издательство: Springer
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Цена: 139750.00 T
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Описание: Proceedings of the 1993 International Workshop on Electronics and Biotechnology Advanced held on the Isle of Elba, Italy, July 13-16, 1993

Автор: Joyce Francis
Название: Biomolecular Engineering: Structures and Functions
ISBN: 1635496497 ISBN-13(EAN): 9781635496499
Издательство: Неизвестно
Цена: 171660.00 T
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Автор: Rostron, Chris (honorary Research Fellow In The School Of Pharmacy And Biomolecular Sciences At Liverpool John Moores University, Honorary Research Fe
Название: Drug design & development paperback
ISBN: 0198749317 ISBN-13(EAN): 9780198749318
Издательство: Oxford Academ
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Цена: 44340.00 T
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Описание: Drug Design and Development outlines the processes involved in the design and development of new drugs and emphasises the significance of these processes to the practice of pharmacy.

Автор: Luigi Salvay
Название: Bioreactors: Animal Cell Culture Control for Bioprocess Engineering
ISBN: 1681176955 ISBN-13(EAN): 9781681176956
Издательство: Gazelle Book Services
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Цена: 230210.00 T
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Описание: Bioreactor is a key device during in vitro animal cell culture. There are several types of bioreactors, including stirred-tank, airlift, hollow-fibre, and Rotary Cell Culture System (RCCS) designs. The stirred-tank bioreactor is one of the most commonly used types, and is used both for industrial applications and laboratory research. The RCCS, invented by NASA, is increasingly used in the area of tissue engineering for medical purposes. Important improvements have been made in the design of traditional bioreactors, and new types of bioreactor are also being developed such as Couette-Taylor bioreactor, multifunctional-membrane bioreactor, and shaking bioreactor. It provides an appropriate growth environment for the cells, enabling them to proliferate and become the final bio-product. Since animal cells are different from microbial cells in morphology, culture skill needed, and mechanical stimulation needed, the traditional microbial bioreactors are not suitable for the large-scale animal cell culture any more, and many new bioreactors are developed. Bioreactors play a key role in the field of biologics, where they are used for the production of recombinant therapeutic proteins by large-scale cultivation of animal cells. Work is also progressing on techniques to improve the performance of bioreactors, including perfusion culture, the use of microcarriers, and methods of suppressing apoptosis and of monitoring cell growth in real time. Given the demand for the production by animal cells for use in the growing number of clinical applications, further advances in bioreactor technology can be expected during the next few years. Bioreactors: Animal Cell Culture Control for Bioprocess Engineering presents the design, fabrication, and control of a new type of bioreactor meant especially for animal cell line culture. It reviews the bioreactors particularly designed for the animal cell culture, and addresses the mechanical loads on the cultured cells. Animal cell processes are primarily used for the production of proteins and viral vaccines of relatively high value. Recent advancements in animal cell bioreactor are reviewed. Most previous concerns about the potential difficulties in scaling-up animal cell processes have been alleviated by the developments in bioreactors.

Автор: Saha, Goutam ; Barua, Al
Название: Bioreactors
ISBN: 1498735991 ISBN-13(EAN): 9781498735995
Издательство: Taylor&Francis
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Цена: 107190.00 T
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Автор: Turksen
Название: Bioreactors in Stem Cell Biology
ISBN: 1071620207 ISBN-13(EAN): 9781071620205
Издательство: Springer
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Цена: 121110.00 T
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Описание: This new edition brings together some of the latest developments and protocols reflecting the rapidity with which bioreactor technologies are advancing and being applied. Given that the use of bioreactors in cell biology is becoming more commonplace as attempts are made to scale-up production of various types of cells for regenerative medicine and pharmaceutical purposes, this volume provides practical guidance for navigating research projects. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Bioreactors in Stem Cell Biology: Methods and Protocols, Second Edition will benefit both established investigators and newcomers to this dynamic area of study.

Автор: Cabral, Joaquim M.S.
Название: Bioreactors for Stem Cell Expansion and Differentiation
ISBN: 0367732939 ISBN-13(EAN): 9780367732936
Издательство: Taylor&Francis
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Цена: 51030.00 T
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