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Bioreactors: Animal Cell Culture Control for Bioprocess Engineering, Luigi Salvay


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Автор: Luigi Salvay
Название:  Bioreactors: Animal Cell Culture Control for Bioprocess Engineering
ISBN: 9781681176956
Издательство: Gazelle Book Services
Классификация:

ISBN-10: 1681176955
Обложка/Формат: Hardback
Страницы: 304
Вес: 0.00 кг.
Дата издания: 01.01.2018
Серия: Engineering
Язык: English
Размер: 230 x 155
Читательская аудитория: Professional & vocational
Ключевые слова: Pharmaceutical technology
Подзаголовок: Animal cell culture control for bioprocess engineering
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Поставляется из: Англии
Описание: Bioreactor is a key device during in vitro animal cell culture. There are several types of bioreactors, including stirred-tank, airlift, hollow-fibre, and Rotary Cell Culture System (RCCS) designs. The stirred-tank bioreactor is one of the most commonly used types, and is used both for industrial applications and laboratory research. The RCCS, invented by NASA, is increasingly used in the area of tissue engineering for medical purposes. Important improvements have been made in the design of traditional bioreactors, and new types of bioreactor are also being developed such as Couette-Taylor bioreactor, multifunctional-membrane bioreactor, and shaking bioreactor. It provides an appropriate growth environment for the cells, enabling them to proliferate and become the final bio-product. Since animal cells are different from microbial cells in morphology, culture skill needed, and mechanical stimulation needed, the traditional microbial bioreactors are not suitable for the large-scale animal cell culture any more, and many new bioreactors are developed. Bioreactors play a key role in the field of biologics, where they are used for the production of recombinant therapeutic proteins by large-scale cultivation of animal cells. Work is also progressing on techniques to improve the performance of bioreactors, including perfusion culture, the use of microcarriers, and methods of suppressing apoptosis and of monitoring cell growth in real time. Given the demand for the production by animal cells for use in the growing number of clinical applications, further advances in bioreactor technology can be expected during the next few years. Bioreactors: Animal Cell Culture Control for Bioprocess Engineering presents the design, fabrication, and control of a new type of bioreactor meant especially for animal cell line culture. It reviews the bioreactors particularly designed for the animal cell culture, and addresses the mechanical loads on the cultured cells. Animal cell processes are primarily used for the production of proteins and viral vaccines of relatively high value. Recent advancements in animal cell bioreactor are reviewed. Most previous concerns about the potential difficulties in scaling-up animal cell processes have been alleviated by the developments in bioreactors.

Bioprocess Parameter Control

Автор: P. Agrarwal; A. Fiechter; C. Kleinstreuer; H.C. Li
Название: Bioprocess Parameter Control
ISBN: 3662152835 ISBN-13(EAN): 9783662152836
Издательство: Springer
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Цена: 113190.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.

Bioprocess Architecture: Design of Biopharmaceutic al and Vaccine Manufacturing Facilities

Автор: Flickinger
Название: Bioprocess Architecture: Design of Biopharmaceutic al and Vaccine Manufacturing Facilities
ISBN: 1118833678 ISBN-13(EAN): 9781118833674
Издательство: Wiley
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Цена: 145730.00 T
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Описание:

Essential information for architects, designers, engineers, equipment suppliers, and other professionals who are working in or entering the biopharmaceutical manufacturing field

Biomanufacturing facilities that are designed and built today are radically different than in the past. The vital information and knowledge needed to design and construct these increasingly sophisticated biopharmaceutical manufacturing facilities is difficult to find in published literature--and it's rarely taught in architecture or design schools. This is the first book for architects and designers that fills this void. Process Architecture in Biomanufacturing Facility Design provides information on design principles of biopharmaceutical manufacturing facilities that support emerging innovative processes and technologies, use state-of-the-art equipment, are energy efficient and sustainable, and meet regulatory requirements.

Relying on their many years of hands-on design and operations experience, the authors emphasize concepts and practical approaches toward design, construction, and operation of biomanufacturing facilities, including product-process-facility relationships, closed systems and single use equipment, aseptic manufacturing considerations, design of biocontainment facility and process based laboratory, and sustainability considerations, as well as an outlook on the facility of the future.

  • Provides guidelines for meeting licensing and regulatory requirements for biomanufacturing facilities in the U.S.A and WHO--especially in emerging global markets in India, China, Latin America, and the Asia/Pacific regions
  • Focuses on innovative design and equipment, to speed construction and time to market, increase energy efficiency, and reduce footprint, construction and operational costs, as well as the financial risks associated with construction of a new facility prior to the approval of the manufactured products by regulatory agencies
  • Includes many diagrams that clarify the design approach

Process Architecture in Biomanufacturing Facility Design is an ideal text for professionals involved in the design of facilities for manufacturing of biopharmaceuticals and vaccines, biotechnology, and life-science industry, including architects and designers of industrial facilities, construction, equipment vendors, and mechanical engineers. It is also recommended for university instructors, advanced undergraduates, and graduate students in architecture, industrial engineering, mechanical engineering, industrial design, and industrial interior design.


Chemical and Bioprocess Engineering

Автор: Simpson Ricardo
Название: Chemical and Bioprocess Engineering
ISBN: 1461491258 ISBN-13(EAN): 9781461491255
Издательство: Springer
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Цена: 56590.00 T
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Описание: This introductory textbook covers all aspects chemical and bioprocess engineering, and provides a thorough grounding in the fundamentals. It features more than 400 proposed and solved exercises each classified by level of difficulty.

Bioprocess Technology

Автор: Philip Manor; Anton Moser
Название: Bioprocess Technology
ISBN: 1461387507 ISBN-13(EAN): 9781461387503
Издательство: Springer
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Цена: 95770.00 T
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Описание: This book is based on a 1981 German language edition published by Springer- Verlag, Vienna, under the title Bioprozesstechnik. It stems from lectures that I began in 1970 at the Technical University of Graz, Austria, and continued at the University of Western Ontario in London, Canada, 1980;

Bioreactors

Автор: Saha
Название: Bioreactors
ISBN: 1138749680 ISBN-13(EAN): 9781138749689
Издательство: Taylor&Francis
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Цена: 67360.00 T
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Описание:

Bioreactors: Animal Cell Culture Control for Bioprocess Engineering presents the design, fabrication, and control of a new type of bioreactor meant especially for animal cell line culture. The new bioreactor, called the see-saw bioreactor, is ideal for the growth of cells with a sensitive membrane. The see-saw bioreactor derives its name from its principle of operation in which liquid columns in either limb of the reactor alternately go up and down. The working volume of the reactor is small, to within 15 L. However, it can easily be scaled up for large production in volume of cell mass in the drug and pharmaceutical industries.

The authors describe the principle of operation of the see-saw bioreactor and how to automatically control the bioprocess. They discuss different control strategies as well as the thorough experimental research they conducted on this prototype bioreactor in which they applied a time delay control for yield maximization.

To give you a complete understanding of the design and development of the see-saw bioreactor, the authors cover the mathematical model they use to describe the kinetics of fermentation, the genetic algorithms used for deriving the optimal time trajectories of the bioprocess variables, and the corresponding control inputs for maximizing the product yield. One chapter is devoted to the application of time delay control. Following a description of the bioreactor's working setup in the laboratory, the authors sum up their investigation and define the future scope of work in terms of design, control, and software sensors.


Advances and Applications of Partitioning Bioreactors

Автор: Huerta-Ochoa, Sergio
Название: Advances and Applications of Partitioning Bioreactors
ISBN: 0128149965 ISBN-13(EAN): 9780128149966
Издательство: Elsevier Science
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Цена: 185270.00 T
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Описание:

Advances and Applications of Partitioning Bioreactors, Volume 54, presents an updated reference in the field of partitioning bioreactors, addressing the relevance of kinetic determination, cell deactivation and transport phenomena from an engineering point-of-view. Topics covered in this new release include Mass transport phenomena in partitioning bioreactors, Modelling and design of partitioning bioreactors, Population balances for partitioning bioreactors, Solid-liquid partitioning bioreactors for industrial wastewater treatment, Multiphase bioreactors in the Food Industry, Multiphase bioreactors in the pharmaceutical industry, Biological treatment of gas pollutants in partitioning bioreactors, Hydrocarbon biodegradation using airlift bioreactors, and more.

  • Contains contributions from experts in their respective areas
  • Updated, state-of-the-art work on partitioning bioreactors

Bioreactors for Waste Gas Treatment

Автор: C. Kennes; M.C. Veiga
Название: Bioreactors for Waste Gas Treatment
ISBN: 9048157722 ISBN-13(EAN): 9789048157723
Издательство: Springer
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Цена: 204040.00 T
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Описание: The resulting text is a high quality, valuable reference tool for a variety of readers, including graduate and postgraduate students, researchers, professors, engineers, and those professionals who are interested in environmental engineering and, more specifically, in innovative air pollution control technologies.

Bioprocess Design and Control

Автор: R. Aarts; M. Aynsley; J.E. Bailey; P.M. Doran; I.J
Название: Bioprocess Design and Control
ISBN: 3662149591 ISBN-13(EAN): 9783662149591
Издательство: Springer
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Цена: 113190.00 T
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Chemical and Bioprocess Engineering

Автор: Ricardo Simpson; Sudhir K. Sastry
Название: Chemical and Bioprocess Engineering
ISBN: 1493944924 ISBN-13(EAN): 9781493944927
Издательство: Springer
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Цена: 52230.00 T
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Описание: This introductory textbook covers all aspects chemical and bioprocess engineering, and provides a thorough grounding in the fundamentals. It features more than 400 proposed and solved exercises each classified by level of difficulty.

Bioprocess Engineering:

Автор: Liu, Shijie
Название: Bioprocess Engineering:
ISBN: 0444637834 ISBN-13(EAN): 9780444637833
Издательство: Elsevier Science
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Цена: 142470.00 T
Наличие на складе: Поставка под заказ.
Описание: Bioprocess Engineering: Kinetics, Sustainability, and Reactor Design, Second Edition, provides a comprehensive resource on bioprocess kinetics, bioprocess systems, sustainability, and reaction engineering. Author Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics, batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, and bioprocess systems engineering, also introducing key principles that enable bioprocess engineers to engage in analysis, optimization, and design with consistent control over biological and chemical transformations. . The quantitative treatment of bioprocesses is the central theme in this book, with more advanced techniques and applications being covered in depth. This updated edition reflects advances that are transforming the field, ranging from genetic sequencing, to new techniques for producing proteins from recombinant DNA, and from green chemistry, to process stability and sustainability. The book introduces techniques with broad applications, including the conversion of renewable biomass, the production of chemicals, materials, pharmaceuticals, biologics, and commodities, medical applications, such as tissue engineering and gene therapy, and solving critical environmental problems.

Computer and Information Science Applications in Bioprocess Engineering

Автор: A.R. Moreira; Kimberlee K. Wallace
Название: Computer and Information Science Applications in Bioprocess Engineering
ISBN: 9401065640 ISBN-13(EAN): 9789401065641
Издательство: Springer
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Цена: 121110.00 T
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Описание: Proceedings of the NATO Advanced Study Institute on `Use of Computer and Informatic Systems in Bioprocess Engineering`, Ofir, Portugal, May 18-29, 1992

Solid-State Fermentation Bioreactors

Автор: David A. Mitchell; Nadia Krieger; Marin Berovic
Название: Solid-State Fermentation Bioreactors
ISBN: 3642068391 ISBN-13(EAN): 9783642068393
Издательство: Springer
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Цена: 174130.00 T
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Описание: This concise professional reference provides a fundamental framework for the design and operation of solid-state fermentation bioreactors, enabling researchers currently working at laboratory scale to scale up their processes.


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