Signaling Mechanisms Regulating T Cell Diversity and Function, Soboloff, Jonathan
Автор: Ralph A. Bradshaw Название: Regulation of Organelle and Cell Compartment Signaling, ISBN: 0123822130 ISBN-13(EAN): 9780123822130 Издательство: Elsevier Science Рейтинг: Цена: 65110.00 T Наличие на складе: Поставка под заказ. Описание: Suitable for researchers across molecular biology, biochemistry, cell biology and genetics, this title includes articles that emphasize signaling to and from intracellular compartments including transcriptional responses to cytoplasmic and nuclear signaling events, chromatin remodeling and stress responses, and more.
Автор: Avia Rosenhouse-Dantsker; Anna N. Bukiya Название: Cholesterol Modulation of Protein Function ISBN: 3030042774 ISBN-13(EAN): 9783030042776 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In this book, renowned scientists describe the role of steroid chirality and modification of lipid membrane physical properties in the modulation of G protein-coupled receptors and ion channels. The application of commonly-used technical approaches such as mass spectrometry and nucleic magnetic resonance transfer spectroscopy for studies on cholesterol distribution and alteration of lipid bilayer characteristics is also discussed. This book offers comprehensive insights into the current understanding of cholesterol-driven modulation of protein function via mechanisms that extend beyond lipid-protein direct interactions. In the first part, the chapters introduce the reader to the use of the chemical derivatives of cholesterol as a valuable laboratory tool in the studies of cholesterol-driven modulation of protein function. In the second part, examples of cholesterol-induced changes in membrane physical characteristics are presented and discussed in light of their multifaceted contribution to the effect of cholesterol on protein function. The book will be of interest to undergraduate and graduate students as well as basic science and medical researchers with a keen interest in the biophysical properties of cholesterol and physiological consequences of cholesterol presence in biological systems.
Название: Apoptosis, Cell Signaling & Human Diseases. Vol1. 2007 ISBN: 1588296776 ISBN-13(EAN): 9781588296771 Издательство: Springer Рейтинг: Цена: 191560.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Aims to provide developments in cell survival and apoptotic pathways and their involvement in various human diseases. This book contains 31 chapters which have been divided into four sections: Malignant Transformation and Metastasis; Kinases and Phosphatases; Molecular Basis of Cell Death; and Molecular Basis of Disease Therapy.
Автор: Alfred Wittinghofer Название: Ras Superfamily Small G Proteins: Biology and Mechanisms 1 ISBN: 3709118050 ISBN-13(EAN): 9783709118054 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This first of two volumes provides a general overview of the genetics, structure, mechanism and regulation of the Ras superfamily proteins and describes in detail the signaling pathways and processes regulated by specific members of this family. The focus of this first volume is on the Rho and Ras subfamily of small G proteins. Renowned scientists provide insights into the biochemistry of the classical and non-classical small G-protein family members, their spatio-temporal regulation, their effectors and their roles in health and disease. Together with Volume 2, this book provides a comprehensive and state-of-the-art work on small G-proteins (GTPases). It is intended for graduates and professors in biochemistry and cell biology already working on small G-proteins (small GTPases), but also offers an extremely valuable resource for those readers who are new to the field.
Автор: Rakesh Srivastava Название: Apoptosis, Cell Signaling, and Human Diseases ISBN: 1617377139 ISBN-13(EAN): 9781617377136 Издательство: Springer Рейтинг: Цена: 148010.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: These volumes present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways.
This invaluable book provides the first description of the diverse and fascinating functions of heme in life processes for a broad audience. It begins with an introduction of the intricate chemical properties of heme and the history of early observations of human diseases associated with heme. It then proceeds to describe the versatile roles of heme in controlling diverse molecular and cellular processes germane to human life and disease processes. In the second edition, a new chapter is devoted to describe findings about heme uptake, transport, and trafficking of heme synthesis intermediates in mammals. Additionally, a chapter about the newly discovered roles of elevated heme biosynthesis and uptake in lung tumorigenesis is included.
Heme Biology is unified and logical in presentation. It is well suited for students and professionals in life sciences who wish to know about the fascinating biology of heme and its usefulness in health and diseases. It may also be used as a reference book for advanced readers and researchers who are interested in heme biology. The explanations in the book are detailed enough to capture the interest of the curious reader, and complete enough to provide the necessary information for researchers to have an in-depth molecular understanding of heme biology and further their studies in this fascinating realm.
Автор: Bradshaw, Ralph A. Название: Functioning Of Transmembrane Receptors In Signaling Mechanisms ISBN: 0123822114 ISBN-13(EAN): 9780123822116 Издательство: Elsevier Science Рейтинг: Цена: 65110.00 T Наличие на складе: Поставка под заказ. Описание: A primary component of cell signaling research, this title covers the principal membrane-bound receptor families, including their structural organization. It provides research on transmembrane signaling entities and their initiating responses following extracellular stimulation.
Автор: Dennis, Edward A. Название: Transduction Mechanisms In Cellular Signaling ISBN: 0123838622 ISBN-13(EAN): 9780123838629 Издательство: Elsevier Science Рейтинг: Цена: 65110.00 T Наличие на складе: Поставка под заказ. Описание: Cytosol, the liquid found inside cells, is the site for multiple cell processes, including signaling from the cell membrane to sites within the cell. This title includes articles and features research on signaling systems and mutations in transcription factors that provide targets for treating disease.
Автор: Gerard Pasterkamp Название: Semaphorins: Receptor and Intracellular Signaling Mechanisms ISBN: 1441924272 ISBN-13(EAN): 9781441924278 Издательство: Springer Рейтинг: Цена: 213360.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book details our progress in understanding the receptor and intracellular signaling mechanisms utilized by semaphorins. The comprehensive overview of semaphorin biology and signaling presented in this book allows one to compare semaphorin functions between different biological systems.
Автор: David M. Pollock; Robert F. Highsmith Название: Endothelin Receptors and Signaling Mechanisms ISBN: 366211674X ISBN-13(EAN): 9783662116746 Издательство: Springer Рейтинг: Цена: 95770.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Kumar Название: Salinity Responses and Tolerance in Plants, Volume 1 ISBN: 3319756702 ISBN-13(EAN): 9783319756707 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Nevertheless, the biotechnological advents in last decade coupled with the availability of genomic sequences of major crops and model plants have opened new vistas for understanding salinity-responses and improving salinity tolerance in important glycophytic crops.
Автор: Vinay Kumar; Shabir Hussain Wani; Penna Suprasanna Название: Salinity Responses and Tolerance in Plants, Volume 1 ISBN: 3030092941 ISBN-13(EAN): 9783030092948 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Soil salinity is a key abiotic-stress and poses serious threats to crop yields and quality of produce. Owing to the underlying complexity, conventional breeding programs have met with limited success. Even genetic engineering approaches, via transferring/overexpressing a single ‘direct action gene’ per event did not yield optimal results. Nevertheless, the biotechnological advents in last decade coupled with the availability of genomic sequences of major crops and model plants have opened new vistas for understanding salinity-responses and improving salinity tolerance in important glycophytic crops. Our goal is to summarize these findings for those who wish to understand and target the molecular mechanisms for producing salt-tolerant and high-yielding crops. Through this 2-volume book series, we critically assess the potential venues for imparting salt stress tolerance to major crops in the post-genomic era. Accordingly, perspectives on improving crop salinity tolerance by targeting the sensory, ion-transport and signaling mechanisms are presented here in volume 1. Volume 2 will focus on the potency of post-genomic era tools that include RNAi, genomic intervention, genome editing and systems biology approaches for producing salt tolerant crops.
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