Mitochondrial Function, Part A,456, Allison, William S.

Автор: Justin C. St. John
Название: Mitochondrial DNA, Mitochondria, Disease and Stem Cells
ISBN: 1627038671 ISBN-13(EAN): 9781627038676
Издательство: Springer
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Цена: 148010.00 T
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Описание: The reader is then introduced to how mtDNA is transmitted through the oocyte and how stem cells can be used to study mitochondrial biogenesis and mtDNA replication and transcription in undifferentiated pluripotent and differentiating cells and how mitochondria adapt during this process.

Автор: Orrenius
Название: Mitochondrial Signaling in Health and Disease
ISBN: 1439880026 ISBN-13(EAN): 9781439880029
Издательство: Taylor&Francis
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Цена: 193950.00 T
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Описание:

Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.

Автор: Allison, William S.
Название: Mitochondrial Function, Part B,457
ISBN: 0123746221 ISBN-13(EAN): 9780123746221
Издательство: Elsevier Science
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Цена: 175170.00 T
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Описание: Presents methods that have been developed to assess the number and function of nuclear-encoded proteins in the mitochndrion. This work focuses on regulation of mitochondrial function and mitochondrial diseases. It includes a section emphasizing the mitochondrial defects associated with type-2 diabetes.

Автор: J.J. Lemasters; C.R. Hackenbrock; R.G. Thurman; H.
Название: Integration of Mitochondrial Function
ISBN: 1489925538 ISBN-13(EAN): 9781489925534
Издательство: Springer
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Цена: 200260.00 T
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Автор: Volkmar Weissig; Marvin Edeas
Название: Mitochondrial Medicine
ISBN: 1493922874 ISBN-13(EAN): 9781493922871
Издательство: Springer
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Цена: 139750.00 T
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Описание: This expert volume covers an interdisciplinary and rapidly growing area of biomedical research comprising genetic, biochemical, pathological, and clinical studies aimed at the diagnosis and therapy of human diseases which are either caused by or associated with mitochondrial dysfunction.

Автор: J.J. Lemasters; C.R. Hackenbrock; R.G. Thurman; H.
Название: Integration of Mitochondrial Function
ISBN: 0306429993 ISBN-13(EAN): 9780306429996
Издательство: Springer
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Цена: 243800.00 T
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Описание: In aerobic tissues such as heart, brain, kidney, liver and brown fat, mitochon- dria account for more than 20% of cell protein and play an essential role in res- piration, ATP formation, ketogenesis, gluconeogenesis, amino acid metabolism, ureagenesis, thermogenesis and a variety of other metabolic activities. The mecha- nisms by which these activities are integrated and regulated within the overall context of cellular physiology is of much current research interest. In order to bring together scientists examining the various diverse aspects of this overall pro- blem, an International Conference on INTEGRATION OF MITOCHONDRIAL FUNC- TION was held June 4-7, 1987 at the Hanes Art Center on the campus of the Uni- versity of North Carolina at Chapel Hill. The chapters of this volume derive from presentations made at this conference. The focus of INTEGRATION OF MITOCHONDRIAL FUNCTION is on signifi- cant new experimental and theoretical advances concerning integration of mito- chondrial function at the organelle, cell, tissue and whole organism levels of organization.

Автор: Hong Kyu Lee; Salvatore DiMauro; Masashi Tanaka; Y
Название: Mitochondrial Pathogenesis
ISBN: 1573314919 ISBN-13(EAN): 9781573314916
Издательство: Springer
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Цена: 113190.00 T
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Название: Mitochondrial biology and experimental therapeutics.
ISBN: 3319733435 ISBN-13(EAN): 9783319733432
Издательство: Springer
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Цена: 167700.00 T
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Описание: This book addresses the therapeutic strategies to target mitochondrial metabolism in diseases where the function of that organelle is compromised, and it discusses the effective strategies used to create mitochondrial-targeted agents that can become commercially available drug delivery platforms. The consistent growth of research focused in understanding the multifaceted role of mitochondria in cellular metabolism, controlling pathways related with cell death, and ionic/redox regulation has extended the research of mitochondrial chemical-biological interactions to include various pharmacological and toxicological applications. Not only does the book extensively cover basic mitochondrial physiology, but it also links the molecular interactions within these pathways to a variety of diseases. It is one of the first books to combine state-of-the-art reviews regarding basic mitochondrial biology, the role of mitochondrial alterations in different diseases, and the importance of that organelle as a target for pharmacological and non-pharmacological interventions to improve human health. The different chapters highlight the chemical-biological linkages of the mitochondria in context with drug development and clinical applications.

Автор: Michael Forte; Marco Colombini
Название: Molecular Biology of Mitochondrial Transport Systems
ISBN: 3642789382 ISBN-13(EAN): 9783642789380
Издательство: Springer
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Цена: 121110.00 T
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Описание: Proceedings of the NATO Advanced Research Workshop on Molecular Biology of Mitochondrial Transport Systems, held at Il Ciocco, Italy, September 17 - 21, 1992

Автор: Angelo Azzi; Katarzyna A. Nalecz; Maciej J. Nalecz
Название: Anion Carriers of Mitochondrial Membranes
ISBN: 3642745415 ISBN-13(EAN): 9783642745416
Издательство: Springer
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Цена: 102480.00 T
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Описание: All relevant structural and functional aspects of the Anion Carriers of Mitochondrial Membranes as well as isolation procedures, reconstitution experiments and biogenesis of the carriers, kinetics of transport as well as the metabolic regulation mechanisms are treated in this volume.

Автор: Tatiana K. Rostovtseva
Название: Molecular Basis for Mitochondrial Signaling
ISBN: 3319555375 ISBN-13(EAN): 9783319555379
Издательство: Springer
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Цена: 149060.00 T
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Описание: At last, the molecular identity of two important channels in the mitochondrial inner membrane, the mitochondrial calcium uniporter and the mitochondrial permeability transition pore have been established.

Автор: Gaetano Santulli
Название: Mitochondrial Dynamics in Cardiovascular Medicine
ISBN: 3319553291 ISBN-13(EAN): 9783319553290
Издательство: Springer
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Цена: 214280.00 T
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Описание: Organized in sections focusing on: basic science, mitochondrial dysfunction in cardiac disorders, in vascular disorders, in metabolic disorders, in kidney disease, therapeutic challenges and options, this essential volume fills imperative gaps in understanding and potentially treating several cardiovascular disorders.