Membrane Protein Crystallization,63, DeLucas, Larry
Автор: Hunte, Carola Название: Membrane Protein Purification and Crystallization ISBN: 0123617766 ISBN-13(EAN): 9780123617767 Издательство: Elsevier Science Рейтинг: Цена: 98810.00 T Наличие на складе: Поставка под заказ.
Автор: Marc L. Pusey; Ramazan Sava? Ayg?n Название: Data Analytics for Protein Crystallization ISBN: 3319589369 ISBN-13(EAN): 9783319589367 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This unique text/reference presents an overview of the computational aspects of protein crystallization, describing how to build robotic high-throughput and crystallization analysis systems. The coverage encompasses the complete data analysis cycle, including the set-up of screens by analyzing prior crystallization trials, the classification of crystallization trial images by effective feature extraction, the analysis of crystal growth in time series images, the segmentation of crystal regions in images, the application of focal stacking methods for crystallization images, and the visualization of trials.
Topics and features: describes the fundamentals of protein crystallization, and the scoring and categorization of crystallization image trials; introduces a selection of computational methods for protein crystallization screening, and the hardware and software architecture for a basic high-throughput system; presents an overview of the image features used in protein crystallization classification, and a spatio-temporal analysis of protein crystal growth; examines focal stacking techniques to avoid blurred crystallization images, and different thresholding methods for binarization or segmentation; discusses visualization methods and software for protein crystallization analysis, and reviews alternative methods to X-ray diffraction for obtaining structural information; provides an overview of the current challenges and potential future trends in protein crystallization.
This interdisciplinary work serves as an essential reference on the computational and data analytics components of protein crystallization for the structural biology community, in addition to computer scientists wishing to enter the field of protein crystallization.
Автор: Gunton Название: Protein Condensation ISBN: 1107424275 ISBN-13(EAN): 9781107424272 Издательство: Cambridge Academ Рейтинг: Цена: 53850.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: For an interdisciplinary graduate and academic audience, this book describes protein crystallization from solution. The first part explains the production of high quality protein crystals, which is necessary to understand protein structure and function. The second part concerns the aggregation of proteins in undesirable ways, which can cause disease.
Автор: Michel Fleck; Aram M. Petrosyan Название: Salts of Amino Acids ISBN: 3319062980 ISBN-13(EAN): 9783319062983 Издательство: Springer Рейтинг: Цена: 174150.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Over the last decades, amino acids have been found to be of importance in many fields of science. Additional data on structural properties, crystal growth and the relation of structure and physical properties of amino acid salts is discussed.
Автор: Lacapere Jean-Jacques Название: Membrane Protein Structure and Function Characterization: Methods and Protocols ISBN: 1493983997 ISBN-13(EAN): 9781493983995 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In this present volume, different approaches are detailed to produce membrane proteins, purify them, study their function, determine their structure, and model them in membrane.
Автор: Moraes Isabel Название: The Next Generation in Membrane Protein Structure Determination ISBN: 3319817159 ISBN-13(EAN): 9783319817156 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
1. Expression Screening of Integral Membrane Proteins by Fusion to Fluorescent Reporters;Louise E. Bird, Joanne E. Nettleship, Valtteri Jдrvinen, Heather Rada, Anil Verma and Raymond J Owens
2. Detergents in Membrane Protein Purification and Crystallisation;Anandhi Anandan and Alice Vrielink
3. NMR of Membrane Proteins: Beyond Crystals;Sundaresan Rajesh, Michael Overduin and Boyan B. Bonev
4. Characterisation of Conformational and Ligand Binding Properties of Membrane Proteins Using Synchrotron Radiation Circular Dichroism (SRCD); Rohanah Hussain and Giuliano Siligardi
5. Membrane Protein Crystallization: Current Trends and Future Perspectives;Joanne L. Parker and Simon Newstead
6. Crystal Dehydration in Membrane Protein Crystallography;Juan Sбnchez-Weatherby and Isabel Moraes
7. Nonlinear Optical Characterization of Membrane Protein Microcrystals and Nanocrystals; Justin A. Newman and Garth J. Simpson
8. Exploiting Microbeams for Membrane Protein Structure Determination;Anna J. Warren, Danny Axford, Neil G. Paterson and Robin L. Owen
9. Applications of the BLEND Software to Crystallographic Data from Membrane Proteins;Pierre Aller, Tian Geng, Gwyndaf Evans and James Foadi
10. Serial Millisecond Crystallography of Membrane Proteins;Kathrin Jaeger, Florian Dworkowski, Przemyslaw Nogly, Christopher Milne, Meitian Wang and Joerg Standfuss
11. Serial Femtosecond Crystallography of Membrane Proteins;Lan Zhu, Uwe Weierstall, Vadim Cherezov and Wei Liu
12. Beyond Membrane Protein Structure: Drug Discovery, Dynamics and Difficulties;Philip C. Biggin, Matteo Aldeghi, Michael J. Bodkin and Alexander Heifetz
INDEX
Автор: Sara Bobone Название: Peptide and Protein Interaction with Membrane Systems ISBN: 3319064339 ISBN-13(EAN): 9783319064338 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In her thesis, Sara Bobone outlines spectroscopic studies of antimicrobial peptides (AMPs) which are promising lead compounds for drugs used to fight multidrug resistant bacteria.
Автор: Sara Bobone Название: Peptide and Protein Interaction with Membrane Systems ISBN: 331938273X ISBN-13(EAN): 9783319382739 Издательство: Springer Рейтинг: Цена: 87060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In her thesis, Sara Bobone outlines spectroscopic studies of antimicrobial peptides (AMPs) which are promising lead compounds for drugs used to fight multidrug resistant bacteria.
Автор: Jordi H. Borrell; ?scar Dom?nech; Kevin M.W. Keoug Название: Membrane Protein – Lipid Interactions: Physics and Chemistry in the Bilayer ISBN: 3319302752 ISBN-13(EAN): 9783319302751 Издательство: Springer Рейтинг: Цена: 60940.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book has been conceives as a brief introduction to biomembranes physical chemistry for undergraduate students of sciences, and it is particularly dedicated to the lipid-protein membrane interactions.
Автор: Jean-Jacques Lacapere Название: Membrane Protein Structure and Function Characterization ISBN: 1493971492 ISBN-13(EAN): 9781493971497 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In this present volume, different approaches are detailed to produce membrane proteins, purify them, study their function, determine their structure, and model them in membrane.
Автор: Sajal Chakraborti; Naranjan S Dhalla Название: Regulation of Membrane Na+-K+ ATPase ISBN: 3319247484 ISBN-13(EAN): 9783319247489 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Na+-K+ ATPase or Na-pump ATPase, a member of “P”-type ATPase superfamily, is characterized by association of multiple isoforms mainly of it’s ?- and ?- subunits. At present four different ?- (?-1,?-2,?-3 and ?-4) and three ?- (?-1, ?-2, and ?-3) isoforms have been identified in mammalian cells and their differential expressions are tissue specific. Regulation of Na+-K+ ATPase activity is an important but a complex process, which involves short-term and long-term mechanisms. Short-term regulation of Na+-K+ ATPase is either mediated by changes in intracellular Na+ concentrations that directly affect the Na+-pump activity or by phosphorylation/dephosphorylation-mediated by some stimulants leading to changes in its expression and transport properties. On the other hand, long-term regulation of Na+-K+ ATPase is mediated by hormones, such as mineralocorticoids and thyroid hormones, which cause changes in the transcription of genes of ?- and ?- subunits leading to an increased expression in the level of Na+-pump. Several studies have revealed a relatively new type of regulation that involves the association of small, single span membrane proteins with this enzyme. These proteins belong to the FXYD family, the members of which share a common signature sequence encompassing the transmembra ne domain adjacent to the isoform(s) of ?-? subunits of Na+-K+ ATPase. Considering the extraordinary importance of Na+-K+ ATPase in cellular function, several internationally established investigators have contributed their articles in the monograph entitled “Regulation of Membrane Na+-K+ ATPase” for inspiring young scientists and graduate students to enrich their knowledge on the enzyme, and we are sure that this book will soon be considered as a comprehensive scientific literature in the area of Na+-K+ ATPase regulation in health and disease.
Автор: J. Robin Harris; Egbert J. Boekema Название: Membrane Protein Complexes: Structure and Function ISBN: 9811339945 ISBN-13(EAN): 9789811339943 Издательство: Springer Рейтинг: Цена: 326090.00 T Наличие на складе: Поставка под заказ. Описание: This edited book contains a compilation of 14 advanced academic chapters dealing with the structure and function of membrane protein complexes. This rapidly advancing important field of study closely parallels those on soluble protein complexes, and viral protein and nucleoprotein complexes. Diverse topics are included in this book, ranging from membrane–bound enzymes to ion channels, proton pumps and photosystems. Data from X-ray crystallography, cryo-electron microscopy and other biophysical and biochemical techniques are presented throughout the book. There is extensive use of colour figures of protein structures. Throughout the book structure and function are closely correlated. The two editors, Egbert Boekema and J. Robin Harris, have worked on aspects of membrane and soluble proteins throughout their scientific careers and also have much publishing experience. The Subcellular Biochemistry series has expanded considerably in recent years, including several related volumes. The theme of protein complexes will be continued within several future volumes, thereby creating encyclopaedic coverage. The chapter topics within this book are particularly relevant to those involved in the biological and biomedical sciences. It is aimed at the advanced undergraduates, postgraduates and established researchers within this broad field. It is hoped that the book will be of interest and use to those involved with the study of cellular membranes and their associated proteins.
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