Plants produce secondary metabolites that humans harness for their own benefit. About half of drugs currently in clinical use are based on these chemicals found in nature. Chemistry of Natural Products covers secondary metabolites present in medicinal plants and their biosynthesis, biological activities, and isolation and separation techniques. This book is ideal for researchers in the areas of biochemistry, medicine, and pharmacology.
Автор: Patric Название: An Introduction to Medicinal Chemistry.2ed IE ISBN: 0198505337 ISBN-13(EAN): 9780198505334 Издательство: Oxford Academ Цена: 17950.00 T Наличие на складе: Поставка под заказ. Описание: This lively, highly illustrated text provides undergraduate and postgraduate students with an accessible introduction to medicinal chemistry. It covers basic principles and background, and then describes the general tactics and strategies involved in developing an effective drug. Through the use of numerous examples it highlights both the difficulties faced by the medicinal chemist and the great potential of rational drug design. The second edition has five new chapters and is updated to include recent advances in the field. Updated throughout with the latest descoveries Five new chapters covering the molecular structure of receptors and the mechanisms of signal transduction combinatorial synthesis the role of computers in drug design adrenergics drug discovery and drug development
Автор: Patrick, Graham L. Название: An Introduction to Medicinal Chemistry ISBN: 0199234477 ISBN-13(EAN): 9780199234479 Издательство: Oxford Academ Рейтинг: Цена: 29560.00 T Наличие на складе: Поставка под заказ. Описание: Assuming minimum background knowledge, the book develops an understanding of the molecular function of drugs and how they interact with the body, before exploring drug discovery and development. It goes on to examine topical issues in applications of medicinal chemistry to novel drug design, to give a contemporary view of the field.
Название: Instant Notes in Medicinal Chemistry ISBN: 1859962076 ISBN-13(EAN): 9781859962077 Издательство: Taylor&Francis Рейтинг: Цена: 29590.00 T Наличие на складе: Поставка под заказ. Описание: Instant Notes in Medicinal Chemistry provides concise coverage for undergraduates studying medicinal chemistry as part of a science, pharmacy or medical course.
Автор: Katja Strohfeldt-Venables Название: Essentials of Inorganic Chemistry: For Students of Pharmacy, Pharmaceutical Sciences and Medicinal Chemistry.- Wiley, 2015 ISBN: 0470665580 ISBN-13(EAN): 9780470665589 Издательство: Wiley Рейтинг: Цена: 49580.00 T Наличие на складе: Поставка под заказ. Описание: A comprehensive introduction to inorganic chemistry and, specifically, the science of metal-based drugs, Essentials of Inorganic Chemistry describes the basics of inorganic chemistry, including organometallic chemistry and radiochemistry, from a pharmaceutical perspective.
Автор: Watson, David G. (Senior Lecturer in Pharmaceutical Sciences, Strathclyde Institute of Pharmaceutical and Biomedical Sciences, University of Strathcly Название: Pharmaceutical and Medicinal Chemistry. Elsevier,2011 ISBN: 9780443072321\Давид Уотсон:Фармацевтическая и лекарственная химия, Элзивир,2011 ISBN: 0443072329 ISBN-13(EAN): 9780443072321 Издательство: Elsevier Science Рейтинг: Цена: 49390.00 T Наличие на складе: Нет в наличии. Описание: Intends to define the area of pharmaceutical chemistry as distinct from medicinal chemistry. This book emphasizes on the physicochemical properties of drug molecules and, in so far as they are known, the way that these properties govern the interaction of the drug with its target.
Автор: Goodnow, Robert Название: Platform Technologies in Drug Discovery and Validation ISBN: 0128130695 ISBN-13(EAN): 9780128130698 Издательство: Elsevier Science Рейтинг: Цена: 154960.00 T Наличие на складе: Нет в наличии. Описание:
Platform Technologies in Drug Discovery and Validation, Volume 50, the latest release in the Annual Reports in Medicinal Chemistry series, provides timely and critical reviews of important topics in medicinal chemistry, with an emphasis on emerging topics in the biological sciences. Topics covered in this new volume include DELT, Oligos: ASO, siRNA, CRISPR, Micro-fluidic chemistry, High throughput screening, Kinase-centric computational drug development, Virtual Screening, Phenotypic screening, PROTACS, Chemical Biology, Fragment-based lead generation, Antibody-Drug Conjugates, Antibody-recruiting small molecules, Deuteration, and Peptides.
Автор: Sarker, Satyajit Dey Название: Medicinal Natural Products: A Disease-Focused Approach,55 ISBN: 0128210192 ISBN-13(EAN): 9780128210192 Издательство: Elsevier Science Рейтинг: Цена: 153830.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Medicinal Natural Products: A Disease-Focused Approach, Volume 55 of the Annual Reports in Medicinal Chemistry series, highlights the applications of natural products as medicines or prospective medicinal leads for the treatment of various human ailments. Each chapter covers a particular disease area or medical condition - for example, the chapter on anticancer natural products will look into the contributions of natural products in cancer chemotherapy, including the discovery and development of taxol, vincristine and vinblastine as cancer chemotherapeutic agents, and also explore the recent developments in anticancer drug discovery and development from various natural products. All 16 chapters will cover the history, current status and future opportunities of natural products in the treatment and prevention of any particular ailment or medical conditions. Whist the primary focus will be on the medicinal chemistry aspects of these natural products with therapeutic applications, structural modifications and in silico approaches will also be covered. Additionally all chapters will review recent literature of last ten years or so, and present an overview on the developments in respective areas.
Автор: Neidle, Stephen Название: Annual Reports In Medicinal Chemistry,54 ISBN: 0128210176 ISBN-13(EAN): 9780128210178 Издательство: Elsevier Science Рейтинг: Цена: 153830.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
The realisation that human, animal, viral and bacterial genomes all contain over-representation of higher-order quadruplex structures in regulatory and other pharmacologically-useful regions, has led to a large number of studies aimed at exploiting this findings for therapeutic and diagnostic purposes. Quadruplex-binding small molecules are starting to be evaluated in human clinical trials.
Some of the more recent efforts in tuberculosis (TB) and trypanosomiasis drug discovery from both Product Development Partnerships (PDPs) and academia are highlighted in this this volume. Drug discovery approaches include both target- and phenotypic whole cell screening- approaches. Regarding the latter, mechanism of action studies through target identification are also illustrated.
Medicinal Chemistry Approaches to Malaria and Other Tropical Disease, Volume 53 in the Annual Reports in Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
Автор: Caballero, Julio Название: Virtual Screening And Drug Docking,59 ISBN: 0323985955 ISBN-13(EAN): 9780323985956 Издательство: Elsevier Science Рейтинг: Цена: 154960.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: My experience as a State Correction Officer inside New Yorks Prisons. As you read Paul Harringtons day-to-day and month-to-month experiences within the states prison system, you will see a broken system one that is full of loopholes, lies, cover-ups and corruption. This system is full of daily violence and numerous officers are injured by violent inmates. Each officer has their unique view of the prison system. Here, Harrington wishes to share his perspective of how different administrations created changes in the daily operations at Fishkill Correctional Facility, where he was stationed after a 15-month stint at Sing Sing. Not every day was
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