Автор: Mishra Название: Nanomedicine for Drug Delivery and Therapeutics ISBN: 1118414098 ISBN-13(EAN): 9781118414095 Издательство: Wiley Рейтинг: Цена: 136710.00 T Наличие на складе: Поставка под заказ. Описание: This book describes a broad area of nanomedicine which involves mainly applications, diseases, and diagnostics. The comprehensive coverage provides researchers, academics, and health specialists with a great tool, that includes techniques applicable to various uses.
Автор: Gao, Huile Название: Brain Targeted Drug Delivery Systems ISBN: 0128140011 ISBN-13(EAN): 9780128140017 Издательство: Elsevier Science Рейтинг: Цена: 151590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat to human life, this book highlights advances and new research in drug delivery methods to the brain.
Provides an overview of brain targeting drug delivery that is useful to both academic and industry-based researchers
Discusses key points in developing brain targeting drug delivery systems
Summarizes and presents currently available strategies for brain targeting drug delivery
Covers not only current studies and their strengths, but also gives insight into the pitfalls of current research
Автор: Shegokar Название: Exploring Drug Delivery to the Peritoneum ISBN: 3031316932 ISBN-13(EAN): 9783031316937 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The Peritoneal cavity (PC) is the key metastatic site for intra-abdominal malignancies (e.g., GI tract and rectal cancer). PC sites can be used to target several other diseases where lymphatic drug delivery is desired without dumping large amounts of the drug. Till recently, it was thought that treatment with curative intent was impossible but that was challenged by the introduction of cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy (HIPEC), and PIPAC (pressurized intraperitoneal aerosol chemotherapy). Recently, a growing number of preclinical and clinical studies advocate intraperitoneal (IP) chemotherapy as an alternative post-operative therapy for cancer. Although their effectiveness has been proven both experimentally and clinically, there is still little understanding of the role of drug delivery systems (DDS) in targeting drugs in the intraperitoneal (IP) cavity. There are two main challenges one posed by IP cavity where the residence time of a small molecular weight drug (<20 kDa) is not sufficiently long to maintain therapeutic effect. This leads to frequent or continuous dosing. Another challenge is device-related or catheter-related problems, such as catheter obstruction, increased risk of infection, and bowel complications. Overall literature shows that the IP site is satisfactorily explored by clinicians but in terms of drug delivery not that much. One can see a clear-cut gap of expertise exchange between the two fields and guidelines from regulatory lawmakers on new medications. In summary, challenges like delivery to IP cavity, tumor or organ-specific targeting, efficient tissue penetration, optimal cellular uptake and intracellular residence of a drug, biocompatibility, toxicity, etc can be easily solved by smartly designing functional drug delivery systems (both nano and micro). Nanotechnologies have always fascinated humans for several decades and are now widely explored in the biomedical field. Diverse types of nanoparticles are being explored around the world, some examples include biodegradable nanoparticles, green nanoparticles, polymeric nanoparticles, lipid nanoparticles, metal nanoparticles, graphene, carbon nanotubes, and several others. Now a day's nanoparticles are gaining interest for drug targeting of chemotherapeutic drugs, immunotherapy, and gene delivery. Whereas microparticles can be explored for delayed drug delivery to the peritoneal cavity due to relatively slow removal from IP fluid. Hydrogels or other adhesive drug delivery may help to enhance peritoneal adhesions; thereby maintaining the balance between benefit and risk. Overall, drug delivery systems are key in IP targeting. That means drug delivery specialist and clinician needs to be connected to get the best out of this route of drug administration. The present book is a link between pharmaceutical scientists (drug formulators), clinicians, toxicologists, and regulatory experts. This book also provides a new perspective to researchers to divert or guide their research in an optimal way. Exploring Drug Delivery to the Peritoneum serves as a platform for upcoming technologies especially in the medical devices sector to face up and show potential in delivering drugs. It is a chance for commercial partners like insurance companies and the pharma industry to explore this direction.
Автор: Kreuter, Jorg Название: Colloidal Drug Delivery Systems ISBN: 0367402017 ISBN-13(EAN): 9780367402013 Издательство: Taylor&Francis Рейтинг: Цена: 65320.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume provides a single-source of reviews for all the important colloidal drug delivery systems, including nanoparticles, liposomes, niosomes, microemulsions and ointments. Over 1000 bibliographic citations, as well as tables, drawings, equations and photographs, are provided. Arranged in order of increasing physical complexity, this work analyzes developments in the field.
Автор: Braddock Martin Название: Nanomedicines: Design, Delivery and Detection ISBN: 1849739471 ISBN-13(EAN): 9781849739474 Издательство: Royal Society of Chemistry Рейтинг: Цена: 252030.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book will provide an overview of the chemistry of nanocarrier design and the considerations that need to be made when developing a nanomedicine.
Автор: Rosania Название: Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery ISBN: 1071612522 ISBN-13(EAN): 9781071612521 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This thorough book explores some of the most important methods and concepts affecting the quantitative analysis of the transport, targeting, and disposition of chemicals within cells, which in turn impact the macroscopic pharmacokinetics of chemical agents in the whole organism. The first half of the volume focuses on small organic molecules with drug-like characteristics, while the second half delves into the cellular pharmacokinetics of biologics and other macromolecules, including peptide therapeutics, cyclotides, antibodies, as well as nanoparticles, thus creating a comprehensive treatise that approaches cellular pharmacokinetics from the different perspectives of pharmaceutical scientists, chemical biologists, medicinal chemists, and protein engineers dealing with very different chemical agents spanning a wide range of sizes, physicochemical properties, and targeting mechanisms. Written for the Methods in Pharmacology and Toxicology series, chapters provide the kind of key detail and expert implementation advice that leads to excellent results in the lab. Synthetic biologists, biophysicists, and bioengineers are amongst the long list of scientists who could benefit from reading this book or from using it as a textbook. Authoritative and practical, Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery builds on a long history of drug development and the adding of quantitative methods at the cellular scale in order to inspire new approaches to drug development that are better able to take advantage of phenomena such as soluble-to-insoluble phase transitions or bispecific targeting, which could ultimately be exploited for the development of more effective drug delivery systems and therapeutic agents.
Автор: Benson Heather A. E. Название: Fundamentals of Drug Delivery ISBN: 1119769604 ISBN-13(EAN): 9781119769606 Издательство: Wiley Рейтинг: Цена: 198470.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Das Werk vermittelt einen Гœberblick Г1/4ber die Grundlagen der Medikamentenverabreichung und die wichtigsten Prozesse bei der Entwicklung von Systemen zur kontrollierten Medikamentenverabreichung. Im ersten Teil wird das Konzept der Medikamentenverabreichung erlдutert, und es werden die Herausforderungen, Chancen und grundlegenden Prozesse bei der Entwicklung von Systemen zur kontrollierten Verabreichung vorgestellt. Im zweiten Teil geht es um eine umfassende Auseinandersetzung mit den Г1/4blichen Verabreichungswegen bei der kontrollierten Medikamentenverabreichung. Dabei wird in jedem Kapitel die fГ1/4r den jeweiligen Verabreichungsweg relevante Physiologie erlдutert, und es werden insbesondere die Grenzen der Verabreichung aufgezeigt. Im letzten Teil liegt der Schwerpunkt auf den besonderen Herausforderungen bei der kontrollierten Medikamentenverabreichung und fortschrittlichen Verabreichungstechnologien ? auch bei Verabreichungssystemen fГ1/4r biologische Wirkstoffe mit ihren ganz eigenen gewaltigen Herausforderungen.
Автор: Yadav, Awesh K. Название: Nano Drug Delivery Strategies For The Treatment Of Cancers ISBN: 0128197935 ISBN-13(EAN): 9780128197936 Издательство: Elsevier Science Рейтинг: Цена: 153830.00 T Наличие на складе: Поставка под заказ. Описание:
Nano Drug Delivery Strategies for the Treatment of Cancers discusses several current and promising approaches for the diagnosis and treatment of cancer by using the most recent developments in nanomedical technologies. The book presents introductory information about the biology of different types of cancer in order to provide the reader with knowledge on their specificities. In addition, it discusses various novel drug delivery systems, detailing their functionalities, expected outcomes and future developments in the field, focusing on brain, mouth and throat, breast, lung, liver, pancreas, stomach, colon, bool, skin and prostate cancers.
The book is a valuable source for cancer researchers, oncologists, pharmacologists and nanotechnologists who are interested in novel drug delivery systems and devices for treatment of various types of cancer that take advantage of recent advances in this exciting field.
Название: Advances in Pulmonary Drug Delivery ISBN: 1498758045 ISBN-13(EAN): 9781498758048 Издательство: Taylor&Francis Рейтинг: Цена: 183750.00 T Наличие на складе: Поставка под заказ.
Название: Nanobiomaterials ISBN: 1771885912 ISBN-13(EAN): 9781771885911 Издательство: Taylor&Francis Рейтинг: Цена: 148010.00 T Наличие на складе: Поставка под заказ.
Автор: Sebastian, Mathew Название: Nanomedicine and Drug Delivery ISBN: 1926895177 ISBN-13(EAN): 9781926895178 Издательство: Taylor&Francis Рейтинг: Цена: 137810.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
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