Автор: Tamanoi, Fuyuhiko Название: Dna Damage And Double Strand Breaks Part B,52 ISBN: 0323993982 ISBN-13(EAN): 9780323993982 Издательство: Elsevier Science Рейтинг: Цена: 123520.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: My experience as a State Correction Officer inside New Yorks Prisons. As you read Paul Harringtons day-to-day and month-to-month experiences within the states prison system, you will see a broken system one that is full of loopholes, lies, cover-ups and corruption. This system is full of daily violence and numerous officers are injured by violent inmates. Each officer has their unique view of the prison system. Here, Harrington wishes to share his perspective of how different administrations created changes in the daily operations at Fishkill Correctional Facility, where he was stationed after a 15-month stint at Sing Sing. Not every day was
Автор: G.P. Pfeifer Название: Technologies for Detection of DNA Damage and Mutations ISBN: 0306452375 ISBN-13(EAN): 9780306452376 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Reviews a wide range of techniques used in mutagenesis research based on the polymerase chain reaction. This work features techniques such as: DNA damage analysis, DNA repair assays, and mutation detection are a few of the techniques featured. It includes chapters that present detailed experimental protocols benefiting researchers and students.
Автор: Kevin D. Mills Название: Silencing, Heterochromatin and DNA Double Strand Break Repair ISBN: 0792379829 ISBN-13(EAN): 9780792379829 Издательство: Springer Рейтинг: Цена: 153720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The field of DNA repair is vast and advancing rapidly. Although I have no doubt that many breakthroughs in our understanding of chromatin, chromatin regulation, and DNA repair lie in our future, presently this is a new line in inquiry.
Автор: W.E.G. M?ller; H.C. Schr?der Название: Biological Response Modifiers — Interferons, Double-Stranded RNA and 2?,5?-Oligoadenylates ISBN: 3642785514 ISBN-13(EAN): 9783642785511 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Biological response modifiers are increasingly used in viral and cancer therapy. Since alterations of the immune system are the primary symptoms of HIV infection, especially therapies directed towards the modulation of the immune response have been under intense evaluation.
Автор: James L. Keck Название: Single-Stranded DNA Binding Proteins ISBN: 1493962515 ISBN-13(EAN): 9781493962518 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This Methods in Molecular Biology (TM) book offers techniques for examining fundamental properties of SSBs and for exploiting the biochemical functions of SSBs as in vitro and in vivo reagents. Includes materials lists, protocols, troubleshooting tips and more.
Автор: Pumpens, Paul (university Of Latvia) Название: Single-stranded rna phages ISBN: 0367028581 ISBN-13(EAN): 9780367028589 Издательство: Taylor&Francis Рейтинг: Цена: 193950.00 T Наличие на складе: Невозможна поставка. Описание: This is a comprehensive guide to single-stranded RNA phages (family Leviviridae), first discovered in 1961. Special attention will be devoted to modern applications of the RNA phages and their products in nanotechnology, vaccinology, gene discovery, evolutionary and environmental studies.
Автор: Pumpens, Paul Название: Single-stranded RNA phages ISBN: 1032175036 ISBN-13(EAN): 9781032175034 Издательство: Taylor&Francis Рейтинг: Цена: 46950.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Название: DNA Damage Recognition ISBN: 0367392135 ISBN-13(EAN): 9780367392130 Издательство: Taylor&Francis Рейтинг: Цена: 65320.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Stands as the most comprehensive guide to the subject--covering every essential topic related to DNA damage identification and repair.
Covering a wide array of topics from bacteria to human cells, this book summarizes recent developments in DNA damage repair and recognition while providing timely reviews on the molecular mechanisms employed by cells to distinguish between damaged and undamaged sites and stimulate the appropriate repair pathways.
about the editors...
WOLFRAM SIEDE is Associate Professor, Department of Cell Biology and Genetics, University of North Texas Health Science Center, Fort Worth. He received the Ph.D. degree (1986) from Johann Wolfgang Goethe University, Frankfurt Germany.
YOKE WAH KOW is Professor, Department of Radiation Oncology, Emory University School of Medicine, Atlanta, Georgia. He received the Ph.D. degree (1981) from Brandeis University, Waltham, Massachusetts.
PAUL W. DOETSCH is Professor, Departments of Biochemistry, Radiation Oncology, and Hematology and Oncology, and Associate Director for Basic Research, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia. He received the Ph.D. degree (1982) from Temple University School of Medicine, Philadelphia, Pennsylvania.
The stability of the DNA double helix is contingent on fine-tuning a number of physicochemical control parameters. Varying any one of them leads to separation of the two strands, in what constitutes a rare physical example of a thermodynamic phase transition in a one-dimensional system. The present book aims at providing a self-contained account of the statistical physics of cooperative processes in DNA, e.g. thermal and mechanical dissociation, force-induced melting, equilibria of hairpin-like secondary structures. In addition, the book presents some fundamental aspects of DNA elasticity, as observed in key experiments, old and new. The latter include some recently published scattering data on apparently soft, short DNA chains and their interpretation in terms of local structural defects (permanent bends, "kinky DNA", after the original Crick-Klug hypothesis).
The development of mathematical models used (Kratky-Porod polymer chain, Poland-Scheraga and Peyrard-Bishop-Dauxois models of DNA melting) emphasizes the use of realistic parameters and the relevance of practical numerical methods for comparing with experimental data. Accordingly, a large number of specially produced figures has been included.
The presentation is at the level of an advanced undergraduate or introductory graduate course. An extra chapter provides the necessary mathematical background on elasticity of model polymer chains.
Автор: Michael J. Manfredo; Jerry J. Vaske; Andreas Rechk Название: Understanding Society and Natural Resources ISBN: 9401789584 ISBN-13(EAN): 9789401789585 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In this edited open access book leading scholars from different disciplinary backgrounds wrestle with social science integration opportunities and challenges.
Автор: Abhijit Saha Название: Molecular Recognition of DNA Double Helix ISBN: 9811342288 ISBN-13(EAN): 9789811342288 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In this book, the molecular recognition of DNA using small molecules is discussed, with a study of the photochemistry of BrU-labeled DNA. The purposes of the study were to develop small molecules for regenerative medicine, to develop a method to detect the recognition site of small molecules, and to detect the most important biological phenomena using the photochemistry of BrU-labeled DNA. The study began with the design and development of small molecules that can induce pluripotency genes. To deal with the important issue of cell permeability of the original compound, a new analogue of the original with improved gene expression was designed and synthesized. Using the photochemistry of BrU-labeled DNA, crucial biological phenomena such as cooperativity between transcription factors were detected. For the first time, the cooperativity was examined by excess electron transfer assay. DNA was also studied very carefully in order to understand the mechanism of the double-strand break in the UVA micro-irradiation technique. The mechanism of the double strand remained untouched. Nevertheless, the double-strand break mechanism was clearly demonstrated by Hoechst dye, as shown in this book.
Автор: Saha Название: Molecular Recognition of DNA Double Helix ISBN: 9811087458 ISBN-13(EAN): 9789811087455 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In this book, the molecular recognition of DNA using small molecules is discussed, with a study of the photochemistry of BrU-labeled DNA.
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