Автор: Helms, Volkhard Название: Principles of Computational Cell Biology ISBN: 3527333584 ISBN-13(EAN): 9783527333585 Издательство: Wiley Рейтинг: Цена: 79200.00 T Наличие на складе: Поставка под заказ. Описание: This successful text, now in its 2nd ed. , provides an ideal introduction into the possibilities of modeling on a cell biology level. It extends the strengths of the first edition even further while keeping faithful to the trusted hands-on concept and keeping math to the minimum.
Автор: Greg Conradi Smith Название: Cellular Biophysics and Modeling: A Primer on the Computational Biology of Excitable Cells ISBN: 1107005361 ISBN-13(EAN): 9781107005365 Издательство: Cambridge Academ Рейтинг: Цена: 100310.00 T Наличие на складе: Поставка под заказ. Описание: What every neuroscientist should know about the mathematical modeling of excitable cells. Combining empirical physiology and nonlinear dynamics, this text provides an introduction to the simulation and modeling of dynamic phenomena in cell biology and neuroscience. It introduces mathematical modeling techniques alongside cellular electrophysiology. Topics include membrane transport and diffusion, the biophysics of excitable membranes, the gating of voltage and ligand-gated ion channels, intracellular calcium signalling, and electrical bursting in neurons and other excitable cell types. It introduces mathematical modeling techniques such as ordinary differential equations, phase plane, and bifurcation analysis of single-compartment neuron models. With analytical and computational problem sets, this book is suitable for life sciences majors, in biology to neuroscience, with one year of calculus, as well as graduate students looking for a primer on membrane excitability and calcium signalling.
Автор: Carl-Fredrik Mandenius; James A. Ross Название: Cell-Based Assays Using iPSCs for Drug Development and Testing ISBN: 1493994794 ISBN-13(EAN): 9781493994793 Издательство: Springer Рейтинг: Цена: 107130.00 T Наличие на складе: Нет в наличии. Описание: The volume presents a variety of protocols that will be useful to researchers working in the field of disease modeling, drug discovery, and the cell biology of various tissues. Chapters in this book cover topics such as requirements and preconditions for using human induced pluripotent cell lines in assay development; the culture of iPSCs and iPSC-derived cardiomyocytes by bioreactor technologies; distinctions between hepatocytes, vascular endothelial cells, cardiomyocytes, renal podocytes, and neurons; and high content assays of mitochondrial function and autophagy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cell-Based Assay using iPSCs for Drug Development and Testing: Methods and Protocols is a valuable resource for researchers working in this important and developing field of study.
Автор: Carl-Fredrik Mandenius; James A. Ross Название: Cell-Based Assays Using iPSCs for Drug Development and Testing ISBN: 149399476X ISBN-13(EAN): 9781493994762 Издательство: Springer Рейтинг: Цена: 107130.00 T Наличие на складе: Нет в наличии. Описание:
The volume presents a variety of protocols that will be useful to researchers working in the field of disease modeling, drug discovery, and the cell biology of various tissues. Chapters in this book cover topics such as requirements and preconditions for using human induced pluripotent cell lines in assay development; the culture of iPSCs and iPSC-derived cardiomyocytes by bioreactor technologies; distinctions between hepatocytes, vascular endothelial cells, cardiomyocytes, renal podocytes, and neurons; and high content assays of mitochondrial function and autophagy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Cell-Based Assay using iPSCs for Drug Development and Testing: Methods and Protocols is a valuable resource for researchers working in this important and developing field of study.
Автор: Birbrair, Alexander Название: Recent Advances In Ipscs For Therapy ,9 ISBN: 0128238828 ISBN-13(EAN): 9780128238820 Издательство: Elsevier Science Рейтинг: Цена: 153830.00 T Наличие на складе: Нет в наличии. Описание:
The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.
iPSCs - Novel Concepts, Volume 15 addresses how important induced pluripotent stems cells are and how can they can help treat certain diseases.
Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells are being used for treatment of different disorders, such as liver disease, type-1 diabetes, Parkinson's disease, macular degeneration of the retina and much more.
The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field.
Автор: Birbrair, Alexander Название: Current Topics In Ipscs Technology,17 ISBN: 0323998925 ISBN-13(EAN): 9780323998925 Издательство: Elsevier Science Рейтинг: Цена: 151590.00 T Наличие на складе: Нет в наличии. Описание: Luckily, the parking lot only deleted footage every three months because of the relatively heavy flow of tourism that took place at Cramond Ghost Island during the summer months. The old man in charge of the parking lot security cameras asked us why we needed the footage. Ethan told him that I met someone there at noon on a Saturday in July and that the police needed to verify that this meeting took place on that date. The old man had to review footage of the four Saturdays in July. He grumbled as he escorted us to a small viewing room at the rear end of the parking lot. Ethan and I sat down next to the old man as he began his search. He
Автор: Birbrair, Alexander Название: Ipscs - State Of The Science ISBN: 0323857671 ISBN-13(EAN): 9780323857673 Издательство: Elsevier Science Рейтинг: Цена: 153830.00 T Наличие на складе: Нет в наличии. Описание: Luckily, the parking lot only deleted footage every three months because of the relatively heavy flow of tourism that took place at Cramond Ghost Island during the summer months. The old man in charge of the parking lot security cameras asked us why we needed the footage. Ethan told him that I met someone there at noon on a Saturday in July and that the police needed to verify that this meeting took place on that date. The old man had to review footage of the four Saturdays in July. He grumbled as he escorted us to a small viewing room at the rear end of the parking lot. Ethan and I sat down next to the old man as he began his search. He
Автор: Turksen Название: Induced Pluripotent Stem Cells and Human Disease ISBN: 1071625845 ISBN-13(EAN): 9781071625842 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This detailed volume presents a series of protocols that are representative of recent developments and improvements in induced pluripotent stem cells (iPS cells) and corresponding human disease models.
Автор: Yahaya Badrul Hisham Название: Organoid Technology for Disease Modelling and Personalized Treatment ISBN: 3030930556 ISBN-13(EAN): 9783030930554 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Organoid Technology for Disease Modelling and Personalised Treatment provides a comprehensive overview of current knowledge of the organoid as a human-organ-in-a-dish, a powerful new technology for studying fundamental aspects of human organ development and disease progression in the search for drugs for personalised treatment.
Anacйlia Matos, Silvia M M Magalhгes, Michael J Rauh - Immune dysregulation and recurring mutations in myelodysplastic syndromes pathogenesis.
Debojyoti De, Parimal Karmakar, Debalina Bhattacharya - Stem Cell Aging and Regenerative Medicine.
Drashti Desai, R. S. Gaud, Pravin Shende - Potential of Chimeric Antigen Receptor T-cells in cancer therapy.
Ekene Nweke, Deepak B. Thimiri Govindaraj - Drug sensitivity and drug repurposing platform for cancer precision medicine.
Fernando Faunes -Role and regulation of Lin28 in progenitor cells during central nervous system development.
Leila Taghiyar, Shahrbano Jahangir, Mojtaba Khozaei Ravari, Mohammad Amin Shamekhi, Mohamadreza Baghaban Eslaminejad -Cartilage Repair by Mesenchymal Stem Cell-Derived Exosomes: Preclinicaland Clinical Trial Update and Perspectives.
Mabel Catalбn; Catalina Rodrнguez; Ivonne Olmedo; Javiera Carrasco-Rojas; DiegoRojas, Alfredo Molina-Berrнos; Mario Dнaz-Dosque Josй A. Jara - Kaempferol induce cell death and sensitizes human head and neck squamous cell carcinoma cell lines to cisplatin.
Marco Folci, Giacomo Ramponi, Enrico Brunetta - A comprehensive approach to Urticaria: from clinical presentation to modern biological treatments through pathogenesis.
Mrinal K Das, Taral R Lunavat, Hrvoje Miletic, Jubayer A Hossain -The potentials and pitfalls of using adult stem cells in cancer treatment.
Peyvand Parhizkar Roudsari, Sepideh Alavi-Moghadam, Mostafa Rezaei-Tavirani, Parisa Goodarzi, Akram Tayanloo-Beik, Forough Azam Sayahpour; Bagher Larijani, Babak Arjmand - The Outcome of Stem Cell-Based Therapies on the Immune Responses in Rheumatoid Arthritis.
Автор: Davey Smith George, Richmond Rebecca, Pingault Jean-Baptiste Название: Combining Human Genetics and Causal Inference to Understand Human Disease and Development ISBN: 1621823814 ISBN-13(EAN): 9781621823810 Издательство: Неизвестно Рейтинг: Цена: 196570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In human genetics, causal inference methods leverage large omics data sets and phenotypic information to decipher various cause-and-effect relationships in human health and disease (e.g., smoking and lung cancer). The focus of such work is typically on modifiable variables (e.g., behavior or environmental exposure) that impact disease onset, progression, and outcome. A better understanding of these variables can lead to interventions and therapeutics that have a desirable impact on public health. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines advances in causal inference approaches in human genetics and how they are being used to enhance our understanding of human development and disease. The contributors discuss family-based study designs for causal inference, including twin designs, adoption designs, and in vitro fertilization designs, that separate inherited factors from perinatal environmental exposures. They also review various types of Mendelian randomization--a population-based approach that is growing in utility and popularity--as well as their integration with family-based designs. The use of these approaches to investigate causal mechanisms in specific scenarios (e.g., maternal smoking during pregnancy and ADHD in offspring) is also covered. This volume is therefore an essential read for geneticists, epidemiologists, and all biomedical scientists and public health professionals dedicated to using genetic information to improve human health.
Автор: Deric L. Wheeler; Yosef Yarden Название: Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease ISBN: 1493920529 ISBN-13(EAN): 9781493920525 Издательство: Springer Рейтинг: Цена: 148020.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Receptor Tyrosine Kinase: Structure, Functions and Role in Human Disease, for the first time, systematically covers the shared structural and functional features of the RTK family.
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