Exploration of Host Genetic Factors associated with Malaria, Qidwai
Автор: Zach N. Adelman Название: Genetic Control of Malaria and Dengue ISBN: 0128002468 ISBN-13(EAN): 9780128002469 Издательство: Elsevier Science Рейтинг: Цена: 74100.00 T Наличие на складе: Поставка под заказ. Описание:
Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development; various strategies for altering the genome of mosquitoes in beneficial ways; and the regulatory, ethical and social environment concerning these strategies.
For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This book is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown.
Автор: Qidwai Tabish Название: Exploration of Host Genetic Factors Associated with Malaria ISBN: 9813347600 ISBN-13(EAN): 9789813347601 Издательство: Springer Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book is aimed to cover the role of genetic polymorphisms in human genes related to RBC disorders, metabolic enzymes, immune response, and cytoadherence in the susceptibility/resistance to malaria caused by Plasmodium falciparum.
Автор: Maria M.Mota; Ana Rodriguez Название: Malaria ISBN: 3319832395 ISBN-13(EAN): 9783319832395 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Currently, malaria kills more than 300,000 people per year, making it a top priority of world leaders and international organizations, who are working towards implementing and coordinating efforts to eradicate this disease. An effective malaria vaccine is recognized as the key element that will decide between success and failure in this fight. At present, despite intensive research efforts, such a vaccine is not yet available for use.
However, there are a number of advanced candidate vaccines with high chances of success in the short term. Malaria: Immune Response to Infection and Vaccination provides a comprehensive view on the immune response to malaria and to the different vaccines under development. The book offers the following:- Contributions by top research leaders in the field,- Comparisons of the immune responses to both malaria infection and malaria vaccines, which are traditionally treated separately, - Coverage of the immune responses to the different stages of malaria, which are frequently treated as separate fields of research.
Автор: Mary M. Stevenson Название: Revival: Malaria (1989): Host Responses to Infection ISBN: 113856060X ISBN-13(EAN): 9781138560604 Издательство: Taylor&Francis Рейтинг: Цена: 40820.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The purpose of this book is to analyze and determine how a host responds to a blood stage malaria infection. It focuses on strategies for anti-malarial vaccination, genetic control of host resistance to malaria, and the contribution of the host genetic background to resistance or susceptibility to
Автор: Watson Gianna Название: Malaria: Clinical Aspects ISBN: 1632418061 ISBN-13(EAN): 9781632418067 Издательство: Неизвестно Рейтинг: Цена: 155570.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Santiago-Alarcon Diego, Marzal Alfonso Название: Avian Malaria and Related Parasites in the Tropics: Ecology, Evolution and Systematics ISBN: 3030516350 ISBN-13(EAN): 9783030516352 Издательство: Springer Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The Tropics are home to the greatest biodiversity in the world, but tropical species are at risk due to anthropogenic activities, mainly land use change, habitat loss, invasive species, and pathogens.
Автор: Jacques Derek Charlwood Название: The Ecology of Malaria Vectors ISBN: 0367248484 ISBN-13(EAN): 9780367248482 Издательство: Taylor&Francis Рейтинг: Цена: 76550.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This practical book covers all aspects of the biology of malaria vectors, with notes on the vectors of dengue. It is designed to fill the gap between very specialised texts and undergraduate books on general disease vectors, and is ideal as a textbook for postgraduate courses in entomology and mosquito vectors of disease.
Автор: David Sullivan; Sanjeev Krishna Название: Malaria: Drugs, Disease and Post-genomic Biology ISBN: 364206471X ISBN-13(EAN): 9783642064715 Издательство: Springer Рейтинг: Цена: 191550.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Despite rapid increases in knowledge, malaria continues to kill more than a million people each year and causes symptomatic disease in a further 300 million individuals. This volume brings some of the world`s best investigators to describe recent advances in both the scientific and clinical aspects of malaria, and bridges between the two.
Автор: Sherman Irwin W Название: Malaria Vaccines: The Continuing Quest ISBN: 1786340046 ISBN-13(EAN): 9781786340047 Издательство: World Scientific Publishing Рейтинг: Цена: 116160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
In 2013, 200 million people were infected with malaria, resulting in over 584,000 deaths, with the potential to affect over half the world's population. Such is the widespread nature of malaria that it is increasingly believed only a vaccine will lead to its eradication.
Although the first attempt at a vaccine was made a century ago, it is only in the last 30 years that real progress in testing has been made, in the hope of discovering a molecule that can provide long-lasting protection against the disease. In July 2015, GlaxoSmithKline (GSK) announced that after 30 years of research it had received the green light from the European Medicines Agency for the world's first malaria vaccine, RTS, S, for use in African children aged 6 weeks to 17 months.
This book chronicles the development of RTS, S -- done in collaboration with the Walter Reed Army Institute for Research, the PATH Malaria Vaccine Initiative (MVI) and funded in part by the Bill and Melinda Gates Foundation -- as well as previous candidate vaccines. It also focusses on the continuing quest to find more effective vaccines against this continuing health crisis. Finally, it provides an easily understood background on recombinant DNA and monoclonal antibodies and places them in perspective to their contributions to malaria vaccine development.
This book serves as a convenient and easily accessible source of information for students, teachers, microbiologists, parasitologists, physicians, clinicians and research funders.
Автор: Stevenson Название: Malaria (1989) ISBN: 1138106062 ISBN-13(EAN): 9781138106062 Издательство: Taylor&Francis Рейтинг: Цена: 153120.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The purpose of this book is to analyze and determine how a host responds to a blood stage malaria infection. It focuses on strategies for anti-malarial vaccination, genetic control of host resistance to malaria, and the contribution of the host genetic background to resistance or susceptibility to
Автор: Stoute Название: Complement Activation in Malaria Immunity and Pathogenesis ISBN: 3319772570 ISBN-13(EAN): 9783319772578 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Plasmodium falciparum malaria is responsible for the deaths of nearly 500,000 people each year. Much attention has been paid to antibody and cellular mechanisms of immunity against this pathogen. By contrast, the role that the complement system plays in immunity and pathogenesis in this infection is not very well recognized or understood. Based on the work of a number of research groups, we know that complement plays an important role in these processes. In this book, some of the leading scientists in the field discuss the mechanisms of complement activation during malaria infection as well as the role of complement in the pathogenesis of key syndromes such as severe malarial anemia, cerebral malaria, and placental malaria. In addition, they review recently-identified complement evasion strategies of P. falciparum merozoites, and how these mechanisms may translate into paradoxical enhancement of infection rather than protection. Finally, they also discuss the role of the mosquito complement system on immunity against the parasite.
Автор: Sekalala Название: Soft Law and Global Health Problems: Lessons from Responses to HIV/AIDS, Malaria and Tuberculosis ISBN: 1107049520 ISBN-13(EAN): 9781107049529 Издательство: Cambridge Academ Рейтинг: Цена: 105600.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book is for legal, development, policy and health scholars who are interested in global health law. It examines key global health governance questions on how the international community can create access to essential medicines for the millions of people who are suffering from AIDS, tuberculosis and malaria.
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