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Drug Delivery to the Brain, de Lange


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Цена: 158380.00T
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Автор: de Lange
Название:  Drug Delivery to the Brain
ISBN: 9783030887728
Издательство: Springer
Классификация:



ISBN-10: 3030887723
Обложка/Формат: Hardback
Страницы: 806
Вес: 1.40 кг.
Дата издания: 08.06.2022
Серия: AAPS Advances in the Pharmaceutical Sciences Series
Язык: English
Издание: 2nd ed. 2022
Иллюстрации: 179 illustrations, color; 20 illustrations, black and white; xxi, 806 p. 199 illus., 179 illus. in color.
Размер: 235 x 155
Читательская аудитория: Professional & vocational
Основная тема: Chemistry
Подзаголовок: Physiological Concepts, Methodologies and Approaches
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood–brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma. Knowledge of all these factors and their interplay in different conditions is of utmost importance for proper CNS drug development and disease treatment. In recent years much information has become available for a better understanding of the many factors important for CNS drug delivery and how they interact to affect drug action. This book describes small and large drug delivery to the brain with an emphasis on the physiology of the BBB and the principles and concepts for drug delivery across the BBB and distribution within the brain. It contains methods descriptions for studying drug delivery, routes and approaches of administering drugs into the brain, the influence of disease, drug industry perspectives, and a primer on neuroanatomy and physiological considerations written specifically for drug delivery scientists. Therewith, it contributes to an in-depth understanding of the interplay between brain (patho)-physiology and drug characteristics. Furthermore, the content is designed to be both cutting-edge and educational, so that the book can be used in high-level training of academic and industry scientists with full references to original publications.
Дополнительное описание: Part I-Physiology and Basic Principles of Drug Handling for the CNS.- Anatomy and Physiology of the Blood Brain Barriers.- Drug Delivery to the Brain: Integrating Neuroscience, Physiology, and Brain Barriers Science.- Brain Delivery of Therapeutics via Tr


Incognito

Автор: Eagleman David
Название: Incognito
ISBN: 1782112464 ISBN-13(EAN): 9781782112464
Издательство: Canongate
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Цена: 10880.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: David Eagleman`s bestselling, sparkling and provocative book on neuroscience now part of the Canongate Canons series

Drug Delivery

Автор: Anya Hillery
Название: Drug Delivery
ISBN: 1138407364 ISBN-13(EAN): 9781138407367
Издательство: Taylor&Francis
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Цена: 193950.00 T
Наличие на складе: Невозможна поставка.
Описание: This book provides a comprehensive introduction to advanced drug delivery and targeting, covering their principles, current applications, and potential future developments

Nanomedicine for Drug Delivery and Therapeutics

Автор: Mishra
Название: Nanomedicine for Drug Delivery and Therapeutics
ISBN: 1118414098 ISBN-13(EAN): 9781118414095
Издательство: Wiley
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Цена: 136710.00 T
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Описание: This book describes a broad area of nanomedicine which involves mainly applications, diseases, and diagnostics. The comprehensive coverage provides researchers, academics, and health specialists with a great tool, that includes techniques applicable to various uses.

Nucleic Acids As Gene Anticancer Drug Delivery Therapy

Автор: Madkour, Loutfy H.
Название: Nucleic Acids As Gene Anticancer Drug Delivery Therapy
ISBN: 0128197773 ISBN-13(EAN): 9780128197776
Издательство: Elsevier Science
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Цена: 174050.00 T
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Описание:

Nucleic Acids as Gene Anticancer Drug Delivery Therapy highlights the most recent developments in cancer treatment using nucleic acids, nanoparticles and polymer nanoparticles for genomic nanocarriers as drug delivery, including promising opportunities for targeted and combination therapy. The development of a wide spectrum of nanoscale technologies is beginning to change the scientific landscape in terms of disease diagnosis, treatment, and prevention. This book presents the use of nanotechnology for medical applications, focusing on its use for anticancer drug delivery. Various intelligent drug delivery systems such as inorganic nanoparticles and polymer-based drug delivery are discussed. The use of smart drug delivery systems seems to be a promising approach for developing intelligent therapeutic systems for cancer immunotherapies and is discussed in detail along with nucleic acid-targeted drug delivery combination therapy for cancer. Nucleic Acids as Gene Anticancer Drug Delivery Therapy will be a useful reference for pharmaceutical scientists, pharmacologiests, and those involved in nanotechnology and cancer research.


Excipient Applications in Formulation Design and Drug Delivery

Автор: Ajit S Narang, Bristol-Myers Squibb
Название: Excipient Applications in Formulation Design and Drug Delivery
ISBN: 3319202057 ISBN-13(EAN): 9783319202051
Издательство: Springer
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Цена: 174150.00 T
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Описание: In recent years, emerging trends in the design and development of drug products have indicated ever greater need for integrated characterization of excipients and in-depth understanding of their roles in drug delivery applications.

Nano-Biomaterials For Ophthalmic Drug Delivery

Автор: Yashwant Pathak; Vijaykumar Sutariya; Anjali A. Hi
Название: Nano-Biomaterials For Ophthalmic Drug Delivery
ISBN: 3319293443 ISBN-13(EAN): 9783319293448
Издательство: Springer
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Цена: 186330.00 T
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Описание: This consolidated reference book addresses the various aspects of nano biomaterials used in ophthalmic drug delivery, including their characterization, interactions with ophthalmic system and applications in treatments of the ophthalmic diseases and disorders. In the last decade, a significant growth in polymer sciences, nanotechnology and biotechnology has resulted in the development of new nano- and bioengineered nano-bio-materials. These are extensively explored as drug delivery carriers as well as for implantable devices and scaffolds. At the interface between nanomaterials and biological systems, the organic and synthetic worlds merge into a new science concerned with the safe use of nanotechnology and nano­ material design for biological applications. For this field to evolve, there is a need to understand the dynamic forces and molecular components that shape these interactions. While it is impossible to describe with certainty all the bio­ physicochemical interactions at play at the interface, we are at a point where the pockets of assembled knowledge are providing a conceptual framework to guide this exploration, and review the impact on future product development. The book is intended as a valuable resource for academics and pharmaceutical scientists working in the field of polymers, polymers materials for drug delivery, drug delivery systems and ophthalmic drug delivery systems, in addition to medical and health care professionals in these areas.

Nanomaterial-Based Drug Delivery Carriers for Cancer Therapy

Автор: Feng
Название: Nanomaterial-Based Drug Delivery Carriers for Cancer Therapy
ISBN: 9811032971 ISBN-13(EAN): 9789811032974
Издательство: Springer
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Цена: 51230.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This brief summarizes different types of organic and inorganic nanomaterials for drug delivery in cancer therapy. It highlights that precisely designed nanomaterials will be the next-generation therapeutic agents for cancer treatment.

Natural Polymer Drug Delivery Systems

Автор: Bhatia
Название: Natural Polymer Drug Delivery Systems
ISBN: 3319411284 ISBN-13(EAN): 9783319411286
Издательство: Springer
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Цена: 121890.00 T
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Описание: This book describes 200 bio-polymers, including the most recent and advanced nanotechnology applications. The applications of various bio-medical and other future potential uses are covered and examined in depth. Systematic discussion of current leading natural polymers is also included.

Drug Delivery to the Brain

Автор: Margareta Hammarlund-Udenaes; Elizabeth C.M. de La
Название: Drug Delivery to the Brain
ISBN: 1493943669 ISBN-13(EAN): 9781493943661
Издательство: Springer
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Цена: 156720.00 T
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Описание: In this book, experts in the field describe the different approaches for drug delivery to the brain with an emphasis on the physiology of the blood-brain barrier (BBB) and the governing principles and concepts for drug delivery across the BBB.

Blood-Brain Barrier

Автор: David Kobiler; Shlomo Lustig; Shlomo Shapira
Название: Blood-Brain Barrier
ISBN: 1461351413 ISBN-13(EAN): 9781461351412
Издательство: Springer
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Цена: 46570.00 T
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Описание: Proceedings of the 44th OHOLO Conference on Blood-Brain Barrier: Drug Delivery and Brain Pathology, held September 10-14, 2000, Dead Sea, Israel

Brain Targeted Drug Delivery Systems

Автор: Gao, Huile
Название: Brain Targeted Drug Delivery Systems
ISBN: 0128140011 ISBN-13(EAN): 9780128140017
Издательство: Elsevier Science
Рейтинг:
Цена: 151590.00 T
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Описание:

Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat to human life, this book highlights advances and new research in drug delivery methods to the brain.

  • Provides an overview of brain targeting drug delivery that is useful to both academic and industry-based researchers
  • Discusses key points in developing brain targeting drug delivery systems
  • Summarizes and presents currently available strategies for brain targeting drug delivery
  • Covers not only current studies and their strengths, but also gives insight into the pitfalls of current research

Nanomedicines for Brain Drug Delivery

Автор: Morales Javier O., Gaillard Pieter J.
Название: Nanomedicines for Brain Drug Delivery
ISBN: 1071608371 ISBN-13(EAN): 9781071608371
Издательство: Springer
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Цена: 121110.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume explores the latest research in central nervous system (CNS) targeted nanocarriers, methods for their synthesis, and its characterization process. Chapters in this book cover topics such as polymeric nanoparticles and liposomes; self-assembled peptide-based scaffolds for lesions of the nervous system; use of peptides as CNS drugs and as potential carriers to optimize brain-targeted delivery; ways to model and assess blood brain barrier absorption of drugs; and the role of neurodegeneration progress of nanomaterials and their potential toxicity concerns. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Thorough and cutting-edge, Nanomedicines for Brain Drug Delivery is a valuable resource that will help researchers guide and advance the field of nanomedicines for the brain and nervous system.


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