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Formulating Poorly Water Soluble Drugs, Williams III


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Автор: Williams III
Название:  Formulating Poorly Water Soluble Drugs
ISBN: 9783030887186
Издательство: Springer
Классификация:


ISBN-10: 3030887189
Обложка/Формат: Hardback
Страницы: 693
Вес: 1.51 кг.
Дата издания: 03.06.2022
Серия: AAPS Advances in the Pharmaceutical Sciences Series
Язык: English
Издание: 3rd ed. 2022
Иллюстрации: 138 illustrations, color; 142 illustrations, black and white; xii, 693 p. 280 illus., 138 illus. in color.
Размер: 254 x 178
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.
Дополнительное описание: Route-Specific Challenges in the Delivery of Poorly Water-Soluble Drugs.- Optimizing the Formulation of Poorly Water-Soluble Drugs.- Solid-State Techniques for Improving Solubility.- Mechanical Particle-Size Reduction Techniques.- Co-solvent and Complexat


Formulating Poorly Water Soluble Drugs

Автор: Williams III
Название: Formulating Poorly Water Soluble Drugs
ISBN: 3030887219 ISBN-13(EAN): 9783030887216
Издательство: Springer
Рейтинг:
Цена: 214280.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.

Water Soluble Vitamins

Автор: Olaf Stanger
Название: Water Soluble Vitamins
ISBN: 940079441X ISBN-13(EAN): 9789400794412
Издательство: Springer
Рейтинг:
Цена: 191550.00 T
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Описание: With contributions from distinguished chemists, biochemists, biologists and clinicians, this volume presents recent research results and fascinating new knowledge on the role and effects of water soluble vitamins in man, including their clinical potential.

Oral Lipid-Based Formulations

Автор: Hauss, David J.
Название: Oral Lipid-Based Formulations
ISBN: 0824729455 ISBN-13(EAN): 9780824729455
Издательство: Taylor&Francis
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Цена: 183750.00 T
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Drug Delivery Strategies for Poorly Water-Soluble Drugs

Автор: Douroumis
Название: Drug Delivery Strategies for Poorly Water-Soluble Drugs
ISBN: 0470711973 ISBN-13(EAN): 9780470711972
Издательство: Wiley
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Цена: 148840.00 T
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Plant-Plant Allelopathic Interactions II

Автор: Udo Blum
Название: Plant-Plant Allelopathic Interactions II
ISBN: 3319047310 ISBN-13(EAN): 9783319047317
Издательство: Springer
Рейтинг:
Цена: 113190.00 T
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Описание: This volume explores laboratory bioassays used to study the roles of water-soluble compounds in plant-plant allelopathic interactions. It provides blue prints for designing more field-relevant screening and cause and effect laboratory bioassays.

Modern Analytical Methodologies in Fat- and Water- Soluble Vitamines

Название: Modern Analytical Methodologies in Fat- and Water- Soluble Vitamines
ISBN: 0471179426 ISBN-13(EAN): 9780471179429
Издательство: Wiley
Рейтинг:
Цена: 226990.00 T
Наличие на складе: Поставка под заказ.
Описание: This volume provides modern and practical analytical methodologies for the assays in foods, pharmaceuticals and clinical samples. Each chapter is written by experts in the particular area and includes original methods and the normal values which would be expected.

Electron Crystallography of Soluble and Membrane Proteins

Автор: Ingeborg Schmidt-Krey; Yifan Cheng
Название: Electron Crystallography of Soluble and Membrane Proteins
ISBN: 1493958763 ISBN-13(EAN): 9781493958764
Издательство: Springer
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Цена: 153720.00 T
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Описание: This Methods in Molecular Biology (TM) book covers techniques used in electron crystallography, including protein sample preparation, 2D crystallization and more. Offers the detailed descriptions and implementation advice needed to ensure successful results.

Fat-Soluble Vitamins

Автор: Peter J. Quinn; Valerian E. Kagan
Название: Fat-Soluble Vitamins
ISBN: 0306458462 ISBN-13(EAN): 9780306458460
Издательство: Springer
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Цена: 287890.00 T
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Описание: The subject for a volume on the fat-soluble vitamins needs no justification considering the importance of this group of nutrients and the rate of expan- sion of our knowledge of its role in cell biology, genetics, and disease.

The Fat-Soluble Vitamins

Автор: H. DeLuca
Название: The Fat-Soluble Vitamins
ISBN: 1461588723 ISBN-13(EAN): 9781461588726
Издательство: Springer
Рейтинг:
Цена: 46570.00 T
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Описание: We can, therefore, state that vitamin A was certainly one of the first known vitamins, yet its function and the function of the other fat-soluble vitamins had remained largely unknown until recent years.

Fat-Soluble Vitamins

Автор: Peter J. Quinn; Valerian E. Kagan
Название: Fat-Soluble Vitamins
ISBN: 1489917918 ISBN-13(EAN): 9781489917911
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The subject for a volume on the fat-soluble vitamins needs no justification considering the importance of this group of nutrients and the rate of expan- sion of our knowledge of its role in cell biology, genetics, and disease.

Water Insoluble Drug Formulation, 3

Название: Water Insoluble Drug Formulation, 3
ISBN: 149872941X ISBN-13(EAN): 9781498729413
Издательство: Taylor&Francis
Рейтинг:
Цена: 265410.00 T
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Описание: Water-Insoluble Drug Formulation, Third Edition serves as a comprehensive reference for pharmaceutical scientists in the handling of formulation issues related to water-insoluble drugs.

Photostability of Drugs and Drug Formulations

Название: Photostability of Drugs and Drug Formulations
ISBN: 0367394103 ISBN-13(EAN): 9780367394103
Издательство: Taylor&Francis
Рейтинг:
Цена: 65320.00 T
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Описание:

Providing the guidance needed for formulation, handling, and quality control of photolabile drugs, Photostability of Drugs and Drug Formulations, Second Edition explores the significance of new information on drug photoreactivity in a pharmaceutical context. Completely revised and updated, with chapter authors drawn from an international panel of experts, the book supplies the background necessary for planning standardized photochemical stability studies as a part of drug development and formulation work. It contains comprehensive coverage of the physical and chemical aspects of drug photoreactivity, formulation, stability testing, and drug design/discovery in one resource.

The contents have been reorganized to focus on the standardization of photostability testing of drug substances and products, in vitro photoreactivity screening of drugs, and various aspects of the formulation of photoreactive substances. The information on in vitro screening of drug photoreactivity is of great relevance for scientists who are developing and validating a set of testing protocols to address photosafety. Discussing kinetic and chemical aspects of drug photodecomposition as well as the practical problems frequently encountered in photochemical stability testing, this book helps you design a test protocol and interpret the results.

Features

  • Assists non-experts in this field design a test protocol and interpret the results
  • Covers in vitro and in vivo aspects of interactions between drugs and light
  • Explores the kinetic and chemical aspects of drug photodecomposition
  • Discusses the problems frequently encountered in photochemical stability testing
  • Provides guidance on how to address photosafety assessments and labeling requirements of potentially photoreactive drugs
  • Highlights the practical implications of drug photodecomposition from a pharmaceutical viewpoint
  • Offers specific guidance in photos


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