Role of tumor microenvironment in breast cancer and targeted therapies, Mir, Manzoor Ahmad (department Of Bioresources, School Of Biological Sciences, University Of Kashmir, Srinagar, India)

Автор: Ursini-Siegel
Название: The Tumor Microenvironment
ISBN: 1493937995 ISBN-13(EAN): 9781493937998
Издательство: Springer
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Цена: 130430.00 T
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Описание: This book covers core and emerging in vitro and in vivo protocols used to study how various components of the tumor microenvironment are established and subsequently interact with tumor cells to facilitate carcinogenesis. In addition, the book examines research topics including cellular and molecular biology approaches, in vivo genetic approaches, various “omics”-based strategies, therapeutic strategies to target the microenvironment, and, finally, advanced techniques in the fields of tissue engineering and nanotechnology. Written and validated in the laboratories of a number of trusted collaborating authors for the highly successful Methods in Molecular Biology series, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Автор: Lekin Sandra
Название: Breast Cancer: Tumor Microenvironment and Biology
ISBN: 1632410680 ISBN-13(EAN): 9781632410689
Издательство: Неизвестно
Цена: 134050.00 T
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Описание: The causes of cancer are diversified. Cancer is the principal reason of death in the majority of countries and it results in enormous financial, societal and mental burden. Breast cancer is the most diagnosed kind of cancer and the foremost reason of deat

Автор: Andrei Thomas-Tikhonenko
Название: Cancer Genome and Tumor Microenvironment
ISBN: 1461425247 ISBN-13(EAN): 9781461425243
Издательство: Springer
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Цена: 243800.00 T
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Описание: There exists a large body of evidence suggesting that well-known mutations in cancer genes profoundly affect tumor milieu. The reviews in this book explore in detail how tumor microenvironment and progression are "hard-wired" at the genetic level.

Автор: Pawel Kalinski
Название: Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy
ISBN: 3319884506 ISBN-13(EAN): 9783319884509
Издательство: Springer
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Цена: 121110.00 T
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Описание: Recent studies have demonstrated that in addition to promoting tumor progression and protecting tumor cells from the spontaneous immune-mediated rejection and different forms of cancer therapeutics, tumor microenvironment can also be a target and mediator of both standard and newly-emerging forms of cancer therapeutics.

Автор: Matsumura Yasuhiro, Tarin David
Название: Cancer Drug Delivery Systems Based on the Tumor Microenvironment
ISBN: 4431568786 ISBN-13(EAN): 9784431568780
Издательство: Springer
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Цена: 139750.00 T
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Описание: This book proposes the importance of new systems of drug design and delivery based on cancer pathophysiology in addition to cancer molecular and cellular biology.

Автор: Kalinski
Название: Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy
ISBN: 3319675753 ISBN-13(EAN): 9783319675756
Издательство: Springer
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Цена: 167700.00 T
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Описание: The tumor microenvironment has become a very important and hot topic in cancer research within the past few years. The tumor microenvironment is defined as the normal cells, molecules, and blood vessels that surround and feed a tumor cell. As many scientists have realized, studying the tumor microenvironment has become critical to moving the field forward, since there are many players in a tumor’s localized and surrounding area, which can significantly change cancer cell behavior. There is a dual relationship wherein the tumor can change its microenvironment and the microenvironment can affect how a tumor grows and spreads. Tumor Microenvironment in Cancer Progression and Cancer Therapy aims to shed light on the mechanisms, factors, and mediators that are involved in the cancer cell environment. Recent studies have demonstrated that in addition to promoting tumor progression and protecting tumor cells from the spontaneous immune-mediated rejection and different forms of cancer therapeutics, tumor microenvironment can also be a target and mediator of both standard and newly-emerging forms of cancer therapeutics. Thus, the dual role of the tumor microenvironment is the integral focus of the volume.  The volume highlights the bi-directional interactions between tumor cells and non-malignant tumor component during tumor progression and treatment. It also focuses on the three groups of the reactive tumor component: stromal cells, blood vessels and the infiltrating immune cells. These three groups are discussed under the lens of their role in promoting tumor growth, shielding the tumor from rejection and from standard forms of cancer therapies. They are emerging as targets and mediators of standard and new forms of potential therapy.

Автор: Domenico Ribatti
Название: The Role of Microenvironment in the Control of Tumor Angiogenesis
ISBN: 3319278185 ISBN-13(EAN): 9783319278186
Издательство: Springer
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Цена: 121890.00 T
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Описание:

Prelims

1. Tumor microenvironment

1.1. Metastatic cascade

1.2. Epithelial-mesenchymal transition

1.3. The extracellular matrix

2. Tumor blood vessels and tumor endothelial cells

2.1. Tumor basement membrane

Автор: Birbrair Alexander
Название: Tumor Microenvironment: The Role of Chemokines - Part B
ISBN: 3030626571 ISBN-13(EAN): 9783030626570
Издательство: Springer
Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of chemokines in the tumor microenvironment.

Автор: Ribatti Domenico
Название: The Role of Microenvironment in the Control of Tumor Angiogenesis
ISBN: 3319802224 ISBN-13(EAN): 9783319802220
Издательство: Springer
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Цена: 93160.00 T
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Описание: This work describes the importance of tumor microenvironment in favouring tumor progression and angiogenesis. Under physiological conditions, angiogenesis is dependent on the balance of positive and negative angiogenic modulators within the vascular microenvironment and requires the functional activities of a number of molecules, including angiogenic factors, extracellular matrix proteins, adhesion molecules and proteolytic enzymes. In normal tissues, vascular quiescence is maintained by the dominant influence of endogenous angiogenesis inhibitors over angiogenic stimuli. Tumor angiogenesis is linked to a switch in the balance between positive and negative regulators, and mainly depends on the release by inflammatory or neoplastic cells of specific growth factors for endothelial cells, that stimulate the growth of the blood vessels of the host or the down-regulation of natural angiogenesis inhibitors. In particular, the inflammatory infiltrate may contribute to tumor angiogenesis, and there are many reports of associations between tumor inflammatory infiltrate, vascularity and prognosis. New therapeutic approaches have been developed with the aim to control tumor angiogenesis through targeting of different components of tumor microenvironment.

Автор: Birbrair Alexander
Название: Tumor Microenvironment: The Role of Interleukins - Part a
ISBN: 3030383148 ISBN-13(EAN): 9783030383145
Издательство: Springer
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Цена: 93160.00 T
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Описание: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of interleukins in the tumor microenvironment.

Автор: Birbrair Alexander
Название: Tumor Microenvironment: The Role of Interleukins - Part B
ISBN: 3030556166 ISBN-13(EAN): 9783030556167
Издательство: Springer
Цена: 46570.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of interleukins in the tumor microenvironment.

Автор: Birbrair Alexander
Название: Tumor Microenvironment: The Role of Chemokines - Part a
ISBN: 3030366693 ISBN-13(EAN): 9783030366698
Издательство: Springer
Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of chemokines in the tumor microenvironment.