Автор: Manzoor-khan, Suhaiymah Название: Postcolonial banter ISBN: 1912565242 ISBN-13(EAN): 9781912565245 Издательство: Неизвестно Рейтинг: Цена: 12660.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: What happens when we leave the places we`re from? What do we lose, who do we become, and what parts of our pasts are unshakeable? Mannheim`s second story collection focuses on twelve people who have relocated - both voluntarily and involuntarily. Opening with the Miami-set thriller `Noir`, these exquisitely rendered stories will leave you reeling.
Автор: Manzoor Ahmad Mir Название: Immunoglobulins, Magic Bullets and Therapeutic Antibodies ISBN: 153616903X ISBN-13(EAN): 9781536169034 Издательство: Nova Science Рейтинг: Цена: 182680.00 T Наличие на складе: Невозможна поставка. Описание: The book "Immunoglobulins, Magic Bullets and Therapeutic Antibodies" comprises of ten chapters and it describes the origin, history, timeline, production and scope of immunoglobulins which are the central molecules of the immune system around which the field of immunology revolves. This book describes how the immune system responds to injuries and insults by foreign antigens (bacteria, viruses etc) and produces immunoglobulins, which then through various immune response mechanisms protect the body against pathogenic invasions. Further, it discusses how these antigens are involved in the differentiation and maturation of immune cells, how lymph nodes are involved in concentrating the antigens, how immunogenicity of an antigen is affected and how antigenicity of immunogens is related to the immune response. Classification of immunoglobulins and the organization and expression of immunoglobulin genes is described separately. The antigen antibody interactions and antibody dependent cell mediated cytotoxicity are also discussed in separate chapters. The magic bullets or monoclonal antibodies, which have revolutionized the field of immunology, are described in greater detail, their production by hybridoma technology and the important role played by these antibodies in research, diagnostics and therapeutics is also discussed in the book. Lastly the immunodiagnostic techniques like radioimmunoassay (RIA), Enzyme Linked Immunosorbent Assay (ELISA), flowcytometry and their importance in the detection of various kinds of diseases like cancer, HIV-AIDS, tuberculosis, malaria, etc. are discussed in detail as well in the book. The book contains a large number of flow charts, diagrams, depictions and tables highlighting the properties, characteristic features, functions and roles played by these immunoglobulins in various fields of biosciences.
Автор: Manzoor, Sarfraz Название: Greetings from bury park ISBN: 1528867475 ISBN-13(EAN): 9781528867474 Издательство: Неизвестно Рейтинг: Цена: 21550.00 T Наличие на складе: Невозможна поставка.
Автор: Manzoor, Sarfraz Название: They ISBN: 1472266838 ISBN-13(EAN): 9781472266835 Издательство: Hodder Рейтинг: Цена: 20240.00 T Наличие на складе: Нет в наличии. Описание: A powerful and deeply personal exploration of a divided country - and a hopeful vision for change
Автор: Mir Shabir Ahmad, Shah Manzoor Ahmad, Hamdani Afshan Mumtaz Название: Gluten-Free Bread Technology ISBN: 3030738973 ISBN-13(EAN): 9783030738976 Издательство: Springer Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: However, developing gluten-free bread remains a technological challenge due to the key role of gluten in the breadmaking process.Gluten-Free Bread Technology provides an overview of all fundamental issues and key factors associated with gluten-free bread technology, with the emphasis on the most recent findings on the subject.
Автор: Moghal Manzoor Название: IDI Amin: Lion of Africa ISBN: 144903974X ISBN-13(EAN): 9781449039745 Издательство: Неизвестно Цена: 20830.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Manzoor Ahmad Mir Название: Basics and Fundamentals of Immunology ISBN: 1536166391 ISBN-13(EAN): 9781536166392 Издательство: Nova Science Рейтинг: Цена: 149940.00 T Наличие на складе: Невозможна поставка. Описание: Immunology is a distinctive subject that rose in the mid-20th century. The subject developed as scientists started to unravel the mysteries about the defense system against pathogens. Researchers started to understand the mechanisms employed by the innate and the adaptive immune system in defense against pathogens. During the last decade, the subject of immunology has been in sharp focus as the immunotherapies against diseases like cancer and AIDS seems last hope. Employing the bodys own defense system against diseases like cancer and AIDS by activating specific cells of the immune system looks promising, and therapies like CAR-T cell therapy have been approved. In the first edition of the book "The Fundamentals of Immunology" we have explained the basics of the defense system of our body. The book is organised into four volumes. The first volume comprises of ten chapters and it describes the rise, history and scope of immunology and the building blocks of the immune system viz., cells, molecules and organs of the immune system. The second chapter describes the cells of the innate and the adaptive immune system and how the granulocytes and macrophages employ defense mechanisms to protect the body against pathogenic invasions. In the third chapter of this book, we have described the organs of the immune systems and how different organs are involved in the differentiation and maturation of immune cells. The chapter also focused on the structure of lymph nodes and their function in concentrating the antigens. In chapter four of this book, we have described the terms like antigens, immunogens, antigenicity, immunogenicity and how immunogenicity of an antigen is affected and how antigenicity of an immunogens is related to the immune response. The innate and adaptive immune systems and the different types of cells and molecules employed by the two branches of immunity have been described in a separate chapter. The structure and biology of immunoglobulins, their types and function in antigen binding and antibody dependent cellular cytotoxicity (ADCC) have been described well in chapter six. Focus has been laid on the distinction between an antibody and an immunoglobulin. The structure and function and major histocompatibility complex (MHC) has been described. The education of cells about self and non-self during their maturation and the processing and presentation of antigens by MHC bearing cells and how MHC coordinates both humoral and cell-mediated immune responses has been explained well throughout the book. The book has explained the complement system and its components, mechanisms and functions in a separate chapter. At the end of the book, we have given an insight about the vaccines, their history, development and how they are useful and helpful in the defense against diseases. The book also discusses the immune disfunction and diseases associated with the dysregulation of immune responses.
Автор: Manzoor Ahmad Mir Название: Cytokines and their Therapeutic Potential ISBN: 1536170178 ISBN-13(EAN): 9781536170177 Издательство: Nova Science Рейтинг: Цена: 77080.00 T Наличие на складе: Невозможна поставка. Описание: The book "Cytokines and Their Therapeutic Potential" comprises of five chapters and describes the origin, production and scope of cytokines, which are the most important molecules of immune system around which the field of functional immunology revolves. This book describes how the immune system responds to injuries and insults by foreign antigens (bacteria, viruses etc.) and produces cytokines, which then, through various immune response mechanisms, protect the body against pathogenic invasions, how these glycoproteins are involved in the differentiation and maturation of immune cells, how lymph nodes are involved in concentrating the different forms of cytokines, how immunogenicity of a cytokine is affected and how a cytokine is related to the immune response. Various types of cytokines and the organization and expression of cytokine receptors are described separately. The properties, mechanistic function and therapeutic cytokines are also discussed in separate chapters. The characteristics, production and important roles played by different cytokines in research, diagnostics and therapeutics is described separately. Lastly the role of cytokines and chemokines in infectious diseases and their importance in the detection of various kinds of diseases like cancer, HIV-AIDS, tuberculosis, malaria etc. are discussed in detail separately. The book contains a reasonable number of diagrams, flowcharts and tables. Besides this, various interesting and self-explanatory illustrations are incorporated to make the book useful to the students for whom it is written. The question bank, which includes long answer type, short answer type and multiple choice questions with their answers at the very end of each chapter, is developed to get a full grasp of the topic.
Автор: Manzoor, Sarfraz Название: They ISBN: 1472266846 ISBN-13(EAN): 9781472266842 Издательство: Hodder Рейтинг: Цена: 13150.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A powerful and deeply personal exploration of a divided country - and a radical vision for change
Автор: Manzoor, Sarfraz Название: Greetings from bury park ISBN: 1526612089 ISBN-13(EAN): 9781526612083 Издательство: Bloomsbury Рейтинг: Цена: 8900.00 T Наличие на складе: Поставка под заказ. Описание: Across 40 chapters, learners, learning and work are situated within educational, organisational, social, economic and political contexts. Taken together, these contributions paint a picture of evolving perspectives of how scholars from around the world view developments in both theory and practice, and map the shifts in learning and work over the past two decades.
Автор: Manzoor Ahmad Mir Название: Combination Therapies and their Effectiveness in Breast Cancer Treatment ISBN: 1685071953 ISBN-13(EAN): 9781685071950 Издательство: Nova Science Рейтинг: Цена: 215410.00 T Наличие на складе: Невозможна поставка. Описание: This book highlights up-to-date and novel information with clinical aspects regarding breast cancer. It covers aspects ranging from epidemiology, biology, and molecular classification to currently available and potentially new therapeutic options for breast cancer. It highlights insights into breast cancer at the molecular level with a holistic approach to use combinational strategies involving various therapies for targeting different pathways involved in this particular malignancy. This book contains a range of latest resources, including schematic illustrations, recent reviews, and information for patients with breast cancer. Various novel biomarkers that are under clinical investigation will also be discussed in this book. Furthermore, the relapse and recurrence after treatment with various therapies presents a great problem, as it develops resistance to which combinational strategy may prove to be a promising approach, and in this book, we have discussed all the aspects of combination therapy in breast cancer. People including students, research scholars, educators, pharmaceutical professionals, clinicians, researchers, practitioners and patients as well as their family members will find this book very much useful.
Автор: Manzoor Ahmad Mir Название: Reverse Costimulation in the Treatment of Infectious Diseases ISBN: 1628085193 ISBN-13(EAN): 9781628085198 Издательство: Nova Science Рейтинг: Цена: 151000.00 T Наличие на складе: Невозможна поставка. Описание: Cancer is one of the most prominent causes of mortality in children and adults causing about 9 million deaths annually, is a major health problem world-wide. The transformation of normal cells to cancer cells may arise due to dysregulation of oncogenes, tumour suppressers and/or stability genes. These transformed cells are sensed by the cells of the immune system, especially T cells, through specific receptors for an effective immune response. But unfortunately even after the interaction with T cells, an effective immune response is not generated. Considering the importance of costimulation in the regulation of immune responses against relapsed cancer, the manipulation of this pathway to increase immunity, regress the growth, augment the expression of pro-apoptotic molecules and induce the apoptosis of lymphomas represents a potential therapeutic approach. This novel strategy of costimuilation activation/inhibition can be effectively exploited to develop immunotherapy either using humanised antibodies against CD80, CD86 and CD40 or CD28 fusogenic proteins for the treatment of intracellular pathogens like M. tuberculosis, HIV, L donovani, T cruzi, etc. This strategy can also be used as an alternative strategy or in combination with the drugs. Since this approach is based on modulating the immune system of the hosts rather than targeting the pathogen; hence it significantly diminishes chance of emergence of drug resistant strains of pathogens and if applied properly, may overcome the rising menace of infectious diseases. The potent role of costimulatory molecules is aptly established in the optimum activation of T cells and APCs; the cells that play a cardinal role in curbing the infections. Hence, immunotherapy involving costimulatory molecules can be a breakthrough strategy to treat various diseases, minimising side effects inflicted by drug therapies and in restricting the emergence of drug resistance.
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