De-Sequencing: Identity Work with Genes, Mahr Dana, Von Arx Martina
Автор: Mahr Dana, Von Arx Martina Название: De-Sequencing: Identity Work with Genes ISBN: 9811577277 ISBN-13(EAN): 9789811577277 Издательство: Springer Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The book unpacks this type of `sequence-speech` in engaging detail, adopting a personal, social, cultural, and bio-political approach to examine the transformation of human identity and reflexivity in the era of genetic citizenship.
Автор: Urszula Demkow Название: Clinical Applications for Next Generation Sequencing ISBN: 0128017392 ISBN-13(EAN): 9780128017395 Издательство: Elsevier Science Рейтинг: Цена: 83080.00 T Наличие на складе: Нет в наличии. Описание:
Clinical Applications for Next Generation Sequencing provides readers with an outstanding postgraduate resource to learn about the translational use of NGS in clinical environments.
Rooted in both medical genetics and clinical medicine, the book fills the gap between state-of-the-art technology and evidence-based practice, providing an educational opportunity for users to advance patient care by transferring NGS to the needs of real-world patients.
The book builds an interface between genetic laboratory staff and clinical health workers to not only improve communication, but also strengthen cooperation. Users will find valuable tactics they can use to build a systematic framework for understanding the role of NGS testing in both common and rare diseases and conditions, from prenatal care, like chromosomal abnormalities, up to advanced age problems like dementia.
Автор: Shomron Noam Название: Deep Sequencing Data Analysis ISBN: 107161102X ISBN-13(EAN): 9781071611029 Издательство: Springer Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This second edition provides new and updated chapters from expert researchers in the field detailing methods used to study the multi-facet deep sequencing data field.
Автор: Elkins Kelly M., Zeller Cynthia B. Название: Next Generation Sequencing in Forensic Science: A Primer ISBN: 1032072040 ISBN-13(EAN): 9781032072043 Издательство: Taylor&Francis Рейтинг: Цена: 58170.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Next Generation Sequencing in Forensic Science prepares practitioners and students to utilize and implement this new technology into their lab casework for forensic investigations, highlighting early applications of how NGS results have been used in court.
Автор: Volйry Ingrid, Julien Marie-Pierre Название: From Measuring Rods to DNA Sequencing: Assessing the Human ISBN: 9811575843 ISBN-13(EAN): 9789811575846 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book provides a solid basis to understand two centuries of bodily measurement practices and their scientific and political scope throughout the Western world.
Автор: Steven R. Head; Phillip Ordoukhanian; Daniel R. Sa Название: Next Generation Sequencing ISBN: 1493975129 ISBN-13(EAN): 9781493975129 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This volume covers a wide range of various fields of research, with the common thread being Next Generation Sequencing (NGS) related methods and applications, as well as analysis and interpretation of the data obtained. Chapters guide readers through the highly dynamic processes of translational and transcriptional profiling of a cell, method to detect copy number alterations (CNAs), targeted sequencing applications, method called "Hi-Plex" to characterize known polymorphic loci, single-cell of DNA or RNA, identify and characterize rare circulating CD4 T cells, and computational pipeline for RNAseq analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Next Generation Sequencing: Methods and Protocols aims to be useful and informative for further study into this vital field.
Автор: Joseph P Damon Название: Whole Genome Sequencing: Privacy & Security in an Era of Genomic Advancements ISBN: 1631171577 ISBN-13(EAN): 9781631171574 Издательство: Nova Science Рейтинг: Цена: 168950.00 T Наличие на складе: Невозможна поставка. Описание: Over the course of less than a decade, whole genome sequencing has progressed from being one of our nations boldest scientific aspirations to becoming a readily available technique for determining the complete sequence of an individuals deoxyribonucleic acid (DNA) -- that persons unique genetic blueprint. This book focuses on the privacy and progress in whole genome sequencing; and provides a scientific background for policymakers in genetic testing.
Автор: Terry Speed; Michael Waterman Название: Genetic Mapping and DNA Sequencing ISBN: 0387948031 ISBN-13(EAN): 9780387948034 Издательство: Springer Рейтинг: Цена: 167700.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Statistics, mathematics and computing all play important roles in genetics mapping, physical mapping and DNA sequencing, the three key components of the human and other genome projects. This volume reviews recent progress in the area, with emphasis on the theory and application of genetic mapping.
Автор: Kappelmann-Fenzl Melanie Название: Next Generation Sequencing and Data Analysis ISBN: 3030624897 ISBN-13(EAN): 9783030624897 Издательство: Springer Рейтинг: Цена: 79190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This textbook provides step-by-step protocols and detailed explanations for RNA Sequencing, ChIP-Sequencing and Epigenetic Sequencing applications.
Автор: El Bairi Khalid Название: Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing: A Big Chapter in the Tale ISBN: 3030538206 ISBN-13(EAN): 9783030538200 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book reviews the potential of next-generation sequencing (NGS) in research on and management of colorectal cancer (CRC), a leading cause of death worldwide and one of the most biologically and clinically heterogeneous cancers.
Автор: El Bairi Khalid Название: Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing: A Big Chapter in the Tale ISBN: 3030538230 ISBN-13(EAN): 9783030538231 Издательство: Springer Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book reviews the potential of next-generation sequencing (NGS) in research on and management of colorectal cancer (CRC), a leading cause of death worldwide and one of the most biologically and clinically heterogeneous cancers.
Автор: Serghei Mangul; Harry Taegyun Yang; Eleazar Eskin; Название: Hidden Treasures in Contemporary RNA Sequencing ISBN: 3030139727 ISBN-13(EAN): 9783030139728 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Нет в наличии. Описание:
Advances in RNA-sequencing (RNA-seq) technologies have provided an unprecedented opportunity to explore the gene expression landscape across individuals, tissues, and environments by efficiently profiling the RNA sequences present in the samples. When a reference genome sequence or a transcriptome of the sample is available, mapping-based RNA-seq analysis protocols align the RNA-seq reads to the reference sequences, identify novel transcripts, and quantify the abundance of expressed transcripts.
The reads that fail to map to the human reference, known as unmapped reads, are a large and often overlooked output of standard RNA-seq analyses. Even in carefully executed experiments, the unmapped reads can comprise a considerable fraction of the complete set of reads produced, and can arise due to technical sequencing produced by low-quality and error-prone copies of the nascent RNA sequence being sampled. Reads can also remain unmapped due to unknown transcripts, recombined B and T cell receptor sequences, A-to-G mismatches from A-to-I RNA editing, trans-splicing, gene fusion, circular RNAs, and the presence of non-host RNA sequences (e.g. bacterial, fungal, and viral organisms). Unmapped reads represent a rich resource for the study of B and T cell receptor repertoires and the human microbiome system—without incurring the expense of additional targeted sequencing.
This book introduces and describes the Read Origin Protocol (ROP), a tool that identifies the origin of both mapped and unmapped reads. The protocol first identifies human reads using a standard high-throughput algorithm to map them onto a reference genome and transcriptome. After alignment, reads are grouped into genomic (e.g. CDS, UTRs, introns) and repetitive (e.g. SINEs, LINEs, LTRs) categories. The rest of the ROP protocol characterizes the remaining unmapped reads, which failed to map to the human reference sequences.
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