De-Sequencing: Identity Work with Genes, Mahr Dana, Von Arx Martina
Автор: Joseph P Damon Название: Whole Genome Sequencing: Privacy & Security in an Era of Genomic Advancements ISBN: 1631171577 ISBN-13(EAN): 9781631171574 Издательство: Nova Science Рейтинг: Цена: 168950.00 T Наличие на складе: Невозможна поставка. Описание: Over the course of less than a decade, whole genome sequencing has progressed from being one of our nations boldest scientific aspirations to becoming a readily available technique for determining the complete sequence of an individuals deoxyribonucleic acid (DNA) -- that persons unique genetic blueprint. This book focuses on the privacy and progress in whole genome sequencing; and provides a scientific background for policymakers in genetic testing.
Автор: El Bairi Khalid Название: Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing: A Big Chapter in the Tale ISBN: 3030538206 ISBN-13(EAN): 9783030538200 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book reviews the potential of next-generation sequencing (NGS) in research on and management of colorectal cancer (CRC), a leading cause of death worldwide and one of the most biologically and clinically heterogeneous cancers.
Автор: Kappelmann-Fenzl Melanie Название: Next Generation Sequencing and Data Analysis ISBN: 3030624897 ISBN-13(EAN): 9783030624897 Издательство: Springer Рейтинг: Цена: 79190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This textbook provides step-by-step protocols and detailed explanations for RNA Sequencing, ChIP-Sequencing and Epigenetic Sequencing applications.
Автор: Terry Speed; Michael Waterman Название: Genetic Mapping and DNA Sequencing ISBN: 0387948031 ISBN-13(EAN): 9780387948034 Издательство: Springer Рейтинг: Цена: 167700.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Statistics, mathematics and computing all play important roles in genetics mapping, physical mapping and DNA sequencing, the three key components of the human and other genome projects. This volume reviews recent progress in the area, with emphasis on the theory and application of genetic mapping.
Автор: Steven R. Head; Phillip Ordoukhanian; Daniel R. Sa Название: Next Generation Sequencing ISBN: 1493975129 ISBN-13(EAN): 9781493975129 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This volume covers a wide range of various fields of research, with the common thread being Next Generation Sequencing (NGS) related methods and applications, as well as analysis and interpretation of the data obtained. Chapters guide readers through the highly dynamic processes of translational and transcriptional profiling of a cell, method to detect copy number alterations (CNAs), targeted sequencing applications, method called "Hi-Plex" to characterize known polymorphic loci, single-cell of DNA or RNA, identify and characterize rare circulating CD4 T cells, and computational pipeline for RNAseq analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Next Generation Sequencing: Methods and Protocols aims to be useful and informative for further study into this vital field.
Автор: Serghei Mangul; Harry Taegyun Yang; Eleazar Eskin; Название: Hidden Treasures in Contemporary RNA Sequencing ISBN: 3030139727 ISBN-13(EAN): 9783030139728 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Нет в наличии. Описание:
Advances in RNA-sequencing (RNA-seq) technologies have provided an unprecedented opportunity to explore the gene expression landscape across individuals, tissues, and environments by efficiently profiling the RNA sequences present in the samples. When a reference genome sequence or a transcriptome of the sample is available, mapping-based RNA-seq analysis protocols align the RNA-seq reads to the reference sequences, identify novel transcripts, and quantify the abundance of expressed transcripts.
The reads that fail to map to the human reference, known as unmapped reads, are a large and often overlooked output of standard RNA-seq analyses. Even in carefully executed experiments, the unmapped reads can comprise a considerable fraction of the complete set of reads produced, and can arise due to technical sequencing produced by low-quality and error-prone copies of the nascent RNA sequence being sampled. Reads can also remain unmapped due to unknown transcripts, recombined B and T cell receptor sequences, A-to-G mismatches from A-to-I RNA editing, trans-splicing, gene fusion, circular RNAs, and the presence of non-host RNA sequences (e.g. bacterial, fungal, and viral organisms). Unmapped reads represent a rich resource for the study of B and T cell receptor repertoires and the human microbiome system—without incurring the expense of additional targeted sequencing.
This book introduces and describes the Read Origin Protocol (ROP), a tool that identifies the origin of both mapped and unmapped reads. The protocol first identifies human reads using a standard high-throughput algorithm to map them onto a reference genome and transcriptome. After alignment, reads are grouped into genomic (e.g. CDS, UTRs, introns) and repetitive (e.g. SINEs, LINEs, LTRs) categories. The rest of the ROP protocol characterizes the remaining unmapped reads, which failed to map to the human reference sequences.
Автор: Urszula Demkow Название: Clinical Applications for Next Generation Sequencing ISBN: 0128017392 ISBN-13(EAN): 9780128017395 Издательство: Elsevier Science Рейтинг: Цена: 83080.00 T Наличие на складе: Нет в наличии. Описание:
Clinical Applications for Next Generation Sequencing provides readers with an outstanding postgraduate resource to learn about the translational use of NGS in clinical environments.
Rooted in both medical genetics and clinical medicine, the book fills the gap between state-of-the-art technology and evidence-based practice, providing an educational opportunity for users to advance patient care by transferring NGS to the needs of real-world patients.
The book builds an interface between genetic laboratory staff and clinical health workers to not only improve communication, but also strengthen cooperation. Users will find valuable tactics they can use to build a systematic framework for understanding the role of NGS testing in both common and rare diseases and conditions, from prenatal care, like chromosomal abnormalities, up to advanced age problems like dementia.
Автор: Preethi Kartan Название: Next Generation Sequencing & Applications ISBN: 1773611100 ISBN-13(EAN): 9781773611105 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 137940.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Billions of spots of tiny genetic code comprise the human genome. It was DNA sequencing technology that had revolutionized genomic research by decoding the valuable genetic information by giving the picture of an exact order of occurrence of nucleotides in a DNA. The inception of first-generation sequencing method, also called Sanger sequencing took place in 1975. The first major breakthrough of first-generation sequencing comes, when the 13 year log Human Genome Project (HGP) was completed in 2003 at a cost $3 million. With ever increasing demands of researchers and clinicians, complex genomic research require a depth of information which is however beyond the capacity of traditional DNA sequencing technologies. These research questions gaps are very well addressed by Next-generation sequencing (NGS) has filled that gap of cheaper as well as faster sequencing technology.It is just a decade old technology, but it has popularize the next-generation sequencing to high-throughput sequencing hat allow millions to trillions of observations to be made in parallel during a single instrument run. Since the introduction of these technologies, the number of applications and methods that influence the power of genome-scale sequencing has increased exponentially. Although in genome research NGS has mostly superseded conventional Sanger sequencing, it has not yet translated into routine clinical practice.The following chapter will highlight the concepts, technologies, and methods of next-generation sequencing to illustrate the breadth and depth of the applications and research areas that are driving progress in genomics.
Автор: Volйry Ingrid, Julien Marie-Pierre Название: From Measuring Rods to DNA Sequencing: Assessing the Human ISBN: 9811575819 ISBN-13(EAN): 9789811575815 Издательство: Springer Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book provides a solid basis to understand two centuries of bodily measurement practices and their scientific and political scope throughout the Western world.
Автор: Brauner/Boos/Kolbe Название: The Cambridge handbook of group interaction analysis / ISBN: 1107113334 ISBN-13(EAN): 9781107113336 Издательство: Cambridge Academ Рейтинг: Цена: 193250.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This is an essential reference for studying communication in teams and groups. Combining the expertise of 76 leading scholars and practitioners, and applicable across different fields, including psychology, management studies, and education, this Handbook presents the complete methodology for coding and analyzing verbal and nonverbal interaction.
Автор: Jessica Mozersky Название: Risky Genes: Genetics, Breast Cancer and Jewish Identity ISBN: 0415502284 ISBN-13(EAN): 9780415502283 Издательство: Taylor&Francis Рейтинг: Цена: 153120.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Ashkenazi Jews have the highest known population risk of carrying specific mutations in the high-risk breast cancer genes, BRCA1 and BRCA2. This book provides first-hand intimate descriptions of women`s experiences of being Jewish and of being at increased risk of genetic breast cancer.
Название: Cultural policy, work and identity ISBN: 0815399383 ISBN-13(EAN): 9780815399384 Издательство: Taylor&Francis Рейтинг: Цена: 39800.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: How have cultural policies created new occupations and shaped professions? This book explores an often unacknowledged dimension of cultural policy analysis: the professional identity of cultural agents. It analyses the relationship between cultural policy, identity and professionalism and draws from a variety of cultural policies around the world to provide insights on the identity construction processes that are at play in cultural institutions. This book reappraises the important question of professional identities in cultural policy studies, museum studies and heritage studies. The authors address the relationship between cultural policy, work and identity by focusing on three levels of analysis. The first considers the state, the creativity of the power relationship established in cultural policies and the power which structures the symbolic order of cultural work. The second presents community in the cultural policy process, society and collective action, whether it is through the creation of institutions for arts and heritage profession or through resistance to state cultural policies. The third examines the experience of cultural policy by the professional. It illustrates how cultural policy is both a set of contingencies that shape possibilities for professionals, as much as it is a basis for identification and identity construction. The eleven authors in this unique book draw on their experience as artists and researchers from a range of countries, including France, Canada, United Kingdom, United States, and Sweden.
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