Genedis 2018: Genetics and Neurodegeneration, Vlamos Panayiotis

Автор: Vlamos Panayiotis
Название: Genedis 2018: Genetics and Neurodegeneration
ISBN: 3030326322 ISBN-13(EAN): 9783030326326
Издательство: Springer
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Цена: 186330.00 T
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Описание: The 3rd World Congress on Genetics, Geriatrics, and Neurodegenerative Disease Research (GeNeDis 2018), focuses on recent advances in genetics, geriatrics, and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments.

Автор: Y. Mizuno; M.B.H. Youdim; D.B. Calne; R. Horowski;
Название: Advances in Research on Neurodegeneration
ISBN: 3211829342 ISBN-13(EAN): 9783211829349
Издательство: Springer
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Цена: 81050.00 T
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Описание: Alzheimer`s disease is the leading cause of dementia in the elderly people and Parkinson`s disease is one of the major neurologic disorders with the prevalence between 1 and 2/1 000 population in advanced countries. even in Parkinson`s disease, still it is impossible to slow down the disease process with the currently available treatment.

Автор: Kumar, Vijay
Название: Tdp-43 And Neurodegeneration
ISBN: 0128200669 ISBN-13(EAN): 9780128200667
Издательство: Elsevier Science
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Цена: 132500.00 T
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Описание: Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43’s structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics. It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture-based models, systems biology for precision medicine, development of stem cells and mechanism-based therapies that can target ALS and other related neurodegenerative diseases. This book is written for neuroscientists, neurologists, clinicians, advanced graduate students, drug discovery researchers, as well as cellular and molecular biologists involved in ALS, motor neuron disease (MND) and other neurodegenerative disorders.

Название: Neuroinflammation and Neurodegeneration
ISBN: 1493910701 ISBN-13(EAN): 9781493910700
Издательство: Springer
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Цена: 186330.00 T
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Описание: State of the art reviews by experts in the fields of neuroscience, immunology, microbiology/infectious diseases and pharmacology addressing the convergence of the immune system (neuroinflammation) and the loss of neurons (neurodegeneration). Many of the diseases that are discussed in the book are of epidemic proportion, e.g., Alzheimer’s disease, Parkinson’s disease, stroke, viral encephalitides and substance abuse. In addition to discussions of the involvement of neuroinflammation and neurodegeneration in these disorders, scientific reviews are presented on the cells and mediators that participate in defense of and damage to the nervous system. With rare exception, no or inadequate treatment exists for the diseases discussed in this book. An underlying premise of the book is that understanding of their shared pathogenic mechanisms will lead to improved therapies. Given the rapid evolution of the field of Neuroimmune Pharmacology, readers will find this book to be the most timely and authoritative reference on the subject of each of its chapters.

Автор: Thomas Curran; Yves Christen
Название: Two Faces of Evil: Cancer and Neurodegeneration
ISBN: 3642267718 ISBN-13(EAN): 9783642267710
Издательство: Springer
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Цена: 213360.00 T
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Описание: Recent findings suggest that some of the same molecules and biochemical processes underlying cancer may also participate in neurodegeneration. This book brings together experts from both fields with the aim to stimulate transdisciplinary interactions.

Автор: Mousumi Mutsuddi; Ashim Mukherjee
Название: Insights into Human Neurodegeneration: Lessons Learnt from Drosophila
ISBN: 9811322171 ISBN-13(EAN): 9789811322174
Издательство: Springer
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Цена: 139750.00 T
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Описание: This book is aimed at generating an updated reservoir of scientific endeavors undertaken to unravel the complicated yet intriguing topic of neurodegeneration. Scientists from Europe, USA and India who are experts in the field of neurodegenerative diseases have contributed to this book. This book will help readers gain insight into the recent knowledge obtained from Drosophila model, in understanding the molecular mechanisms underlying neurodegenerative disorders and also unravel novel scopes for therapeutic interventions. Different methodologies available to create humanized fly models that faithfully reflects the pathogenicities associated with particular disorders have been described here. It also includes information on the exciting area of neural stem cells. A brief discussion on neurofibrillary tangles, precedes the elaborate description of lessons learnt from Drosophila about Alzheimer's, Parkinson’s, Spinomuscular Atrophy, Huntington’s diseases, RNA expansion disorders and Hereditary Spastic Paraplegia. We have concluded the book with the use of Drosophila for identifying pharmacological therapies for neurodegenerative disorders. The wide range of topics covered here will not only be relevant for beginners who are new to the concept of the extensive utility of Drosophila as a model to study human disorders; but will also be an important contribution to the scientific community, with an insight into the paradigm shift in our understanding of neurodegenerative disorders. Completed with informative tables and communicative illustrations this book will keep the readers glued and intrigued. We have comprehensively anthologized the lessons learnt on neurodegeneration from Drosophila and have thus provided an insight into the multidimensional aspects of pathogenicities of majority of the neurodegenerative disorders.

Автор: A. Israel; B. de Strooper; F. Checler; Y. Christen
Название: Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate
ISBN: 3642627676 ISBN-13(EAN): 9783642627675
Издательство: Springer
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Цена: 139750.00 T
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Описание: Can molecular mechanisms involved in neural development help us to understand, prevent and perhaps reverse the course of brain ageing and neurodegenerative disorders?

Автор: Martin Beckerman
Название: Fundamentals of Neurodegeneration and Protein Misfolding Disorders
ISBN: 3319342843 ISBN-13(EAN): 9783319342849
Издательство: Springer
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Цена: 104480.00 T
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Описание: Starting with protein folding and protein quality control basics, the reader will learn how misfolded proteins can cause diseases ranging from prion diseases to Alzheimer`s disease and Parkinson`s disease to Huntington`s disease, amyotrophic lateral sclerosis and frontotemporal lobar degeneration.

Автор: Farooqui, Akhlaq A. (research Scientist, Department Of Molecular And Cellular Biochemistry, The Ohio State University, Columbus, Oh, Usa)
Название: Molecular aspects of neurodegeneration, neuroprotection, and regeneration in neurological disorders
ISBN: 0128217111 ISBN-13(EAN): 9780128217115
Издательство: Elsevier Science
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Цена: 132500.00 T
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Описание: Letter Jam is a 2-6 player cooperative word game where players assist each other in composing meaningful words from letters around the table. The trick is holding the letter card so that it`s only visible to other players and not to you.At the start of the game, each player receives a set of face-down letter cards that can be arranged to form an existing word. The setup can be prepared by using a special card scanning app, or by players selecting words for each other. Each player then puts their first card in their stand facing the other players without looking at it, and the game begins.The game is played in turns. Each turn, players simultaneously search other players` letters to see what words they can spell out (telling the others the length of the word they can make up). The player who offers the longest word can then be chosen as the clue giver.The clue giver spells out their clue by putting numbered tokens in front of the other players. Number one goes to the player whose letter comes first in the clue, number two to the second letter etc. They can always use a wild card which can be any letter, but they cannot tell others which letter it represents.Each player with a numbered token (or tokens) in front of them then tries to figure out what their letter is. If they do, they place the card face down before revealing the next letter. At the end of the game, players can then rearrange the cards to try to form an existing word. All players then reveal their cards to see if they were successful or not. The more players who have an existing word in front of them, the bigger their common success.

Автор: Milardi Danilo
Название: Neurodegeneration: Metallostasis and Proteostasis
ISBN: 1849730504 ISBN-13(EAN): 9781849730501
Издательство: Royal Society of Chemistry
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Цена: 171760.00 T
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Описание: This exemplary book gives an up-to-date perspective on the role of metal ions in neurodegeneration.

Автор: Giovanni Manfredi; Hibiki Kawamata
Название: Neurodegeneration
ISBN: 1493962205 ISBN-13(EAN): 9781493962204
Издательство: Springer
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Цена: 135090.00 T
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Описание: Neurodegeneration tackles the challenges involved with neurodegenerative disorders, such as Alzheimer`s and Parkinson`s disease. The text presents cutting-edge analytical and technological approaches to study the mechanisms underlying neurodegenerative processes.

Автор: Leonidas Stefanis; J. N. Keller
Название: The Proteasome in Neurodegeneration
ISBN: 1489973451 ISBN-13(EAN): 9781489973450
Издательство: Springer
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Цена: 163040.00 T
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Описание: One major factor that has been relatively obscure until recently has been the contribution of protein degradation to the regulation of the steady state level of protein expression and protein function.