G Protein-Coupled Receptor Screening Assays: Methods and Protocols, Martins Sofia Aires M., Prazeres Duarte Miguel F.

Автор: Duarte Miguel F. Prazeres; Sofia Aires M. Martins
Название: G Protein-Coupled Receptor Screening Assays
ISBN: 1493923358 ISBN-13(EAN): 9781493923359
Издательство: Springer
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Цена: 130430.00 T
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Описание: This volume explores the considerable efforts that have been directed towards the development of G Protein-Coupled Receptors (GPCR) screening assays in order to disclose GPCR acting compounds, elucidate signaling mechanisms or evaluate compound`s efficacy.

Автор: Lieberman Benjamin A.
Название: Steroid Receptor Methods / Protocols and Assays
ISBN: 0896037541 ISBN-13(EAN): 9780896037540
Издательство: Springer
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Цена: 144410.00 T
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Описание: A distinguished team of principal investigators and their associates describe in step-by-step detail a cross-section of the latest research techniques available for studying the endocrine system. As a basis for sophisticated biochemical analysis of receptor properties, the contributors provide methods for the production and purification of a variety of receptors, including progesterone, glucocorticoid, and androgen. Other protocols allow the reader to experiment with DNA binding characteristics, hormone binding assays, and the use of combinatorial chemistry for drug discovery. A series of novel methods utilizing the latest advances in immunochemistry, yeast two-hybrid screening, and fluorescence are included for the detection and analysis of a variety of cellular proteins that influence steroid receptor effectiveness.

Автор: Gurevich Vsevolod V., Gurevich Eugenia V., Tesmer John J. G.
Название: G Protein-Coupled Receptor Kinases
ISBN: 1493981420 ISBN-13(EAN): 9781493981427
Издательство: Springer
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Цена: 93160.00 T
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Описание: This collection explores up-to-date descriptions of known G protein-coupled receptor kinase (GRK)-dependent mechanisms, both associated with G protein-coupled receptor (GPCR) functions and the receptor-independent. The chapters cover a wide range of studies from invertebrates to humans, with sections of the volume covering GRK structure, mechanisms of activation, and interaction with GPCRs, GRKs in cell signaling, as well as physiological and pathophysiological mechanisms regulated by GRKs. Written for the Methods in Pharmacology and Toxicology series, this book features the kind of practical detail necessary for success in the laboratory. Authoritative and timely, G Protein-Coupled Receptor Kinases features the kind of comprehensive mechanistic elucidation of GRK functions and their regulation in cells necessary for a better understanding of cell biology as well as for devising novel research approaches and therapeutic strategies.

Автор: Mark P. Running
Название: G Protein-Coupled Receptor Signaling in Plants
ISBN: 1627035311 ISBN-13(EAN): 9781627035316
Издательство: Springer
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Цена: 97820.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology book describes techniques used in the study of small GTPases and related proteins. Includes a chapter on bioinformatics approaches, plus reproducible protocols, materials lists, practical tips and troubleshooting advice.

Автор: Mario Tiberi
Название: G Protein-Coupled Receptor Signaling
ISBN: 1493991205 ISBN-13(EAN): 9781493991204
Издательство: Springer
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Цена: 167700.00 T
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Описание: This detailed volume assembles comprehensive protocols to assist with the study of structural, molecular, cell biological, and in vivo facets of GPCRs, and to enable the development of experimental tools for screening novel GPCR drugs. Sections explore the tweaking of ligands, bioluminescence and FRET approaches, specific GPCR signaling properties, as well as visualization of subcellular compartmentalization. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Автор: Kim Neve
Название: Functional Selectivity of G Protein-Coupled Receptor Ligands
ISBN: 1493961160 ISBN-13(EAN): 9781493961160
Издательство: Springer
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Цена: 174130.00 T
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Описание: In Functional Selectivity of G Protein-Coupled Receptors, experts review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon.

Автор: Katharine Herrick-Davis; Graeme Milligan; Giuseppe
Название: G-Protein-Coupled Receptor Dimers
ISBN: 3319867954 ISBN-13(EAN): 9783319867953
Издательство: Springer
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Цена: 139750.00 T
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Описание: G-protein-coupled receptors (GPCRs) are believed to be the largest family of membrane proteins involved in signal transduction and cellular responses.

Автор: Craig W. Stevens
Название: G Protein-Coupled Receptor Genetics
ISBN: 1627037780 ISBN-13(EAN): 9781627037785
Издательство: Springer
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Цена: 158380.00 T
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Описание: G Protein-Coupled Receptor Genetics: Research and Methods in the Post-Genomic Era features practical techniques inspired by the fast moving GPCR field.

Автор: Mark P. Running
Название: G Protein-Coupled Receptor Signaling in Plants
ISBN: 1493962167 ISBN-13(EAN): 9781493962167
Издательство: Springer
Рейтинг:
Цена: 97820.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology book describes techniques used in the study of small GTPases and related proteins. Includes a chapter on bioinformatics approaches, plus reproducible protocols, materials lists, practical tips and troubleshooting advice.

Автор: Katharine Herrick-Davis; Graeme Milligan; Giuseppe
Название: G-Protein-Coupled Receptor Dimers
ISBN: 3319601725 ISBN-13(EAN): 9783319601724
Издательство: Springer
Рейтинг:
Цена: 186330.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: G-protein-coupled receptors (GPCRs) are believed to be the largest family of membrane proteins involved in signal transduction and cellular responses.

Автор: Gurevich
Название: G Protein-Coupled Receptor Kinases
ISBN: 1493937960 ISBN-13(EAN): 9781493937967
Издательство: Springer
Рейтинг:
Цена: 130430.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This collection explores up-to-date descriptions of known G protein-coupled receptor kinase (GRK)-dependent mechanisms, both associated with G protein-coupled receptor (GPCR) functions and the receptor-independent. The chapters cover a wide range of studies from invertebrates to humans, with sections of the volume covering GRK structure, mechanisms of activation, and interaction with GPCRs, GRKs in cell signaling, as well as physiological and pathophysiological mechanisms regulated by GRKs. Written for the Methods in Pharmacology and Toxicology series, this book features the kind of practical detail necessary for success in the laboratory.

Автор: Craig W. Stevens
Название: G Protein-Coupled Receptor Genetics
ISBN: 1493963325 ISBN-13(EAN): 9781493963324
Издательство: Springer
Рейтинг:
Цена: 111790.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: G Protein-Coupled Receptor Genetics: Research and Methods in the Post-Genomic Era features practical techniques inspired by the fast moving GPCR field.