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G Protein-Coupled Receptor Signaling, Mario Tiberi


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Цена: 167700.00T
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Ориентировочная дата поставки: Август-начало Сентября
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Автор: Mario Tiberi
Название:  G Protein-Coupled Receptor Signaling
ISBN: 9781493991204
Издательство: Springer
Классификация:





ISBN-10: 1493991205
Обложка/Формат: Hardcover
Страницы: 406
Вес: 1.01 кг.
Дата издания: 2019
Серия: Methods in Molecular Biology
Язык: English
Издание: 1st ed. 2019
Иллюстрации: 71 illustrations, color; 16 illustrations, black and white; xv, 406 p. 87 illus., 71 illus. in color.
Размер: 254 x 178 x 24
Читательская аудитория: Professional & vocational
Основная тема: Life Sciences
Подзаголовок: Methods and Protocols
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This detailed volume assembles comprehensive protocols to assist with the study of structural, molecular, cell biological, and in vivo facets of GPCRs, and to enable the development of experimental tools for screening novel GPCR drugs. Sections explore the tweaking of ligands, bioluminescence and FRET approaches, specific GPCR signaling properties, as well as visualization of subcellular compartmentalization. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, G Protein-Coupled Receptor Signaling: Methods and Protocols serves as an ideal reference for life scientists working in a variety of research fields including molecular pharmacology, cell and developmental biology, brain behavior and physiology, drug development and screening.
Chapter 4 is available open access under a CC BY 4.0 license via link.springer.com.

Дополнительное описание: Assessment of Conformational State Transitions of Class B GPCRs Using Molecular Dynamics.- Molecular Dynamic Simulations to Probe Water Permeation Pathways of GPCRs.- Expression and Purification of a Functional E. coli 13CH3-Methionine-Labeled Thermostabl


Functional Selectivity of G Protein-Coupled Receptor Ligands

Автор: Kim Neve
Название: Functional Selectivity of G Protein-Coupled Receptor Ligands
ISBN: 1493961160 ISBN-13(EAN): 9781493961160
Издательство: Springer
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Цена: 174130.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In Functional Selectivity of G Protein-Coupled Receptors, experts review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon.

G Protein-Coupled Receptors: Signaling, Trafficking and Regulatio

Автор: Arun K. Shukla
Название: G Protein-Coupled Receptors: Signaling, Trafficking and Regulatio
ISBN: 0128035951 ISBN-13(EAN): 9780128035955
Издательство: Elsevier Science
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Цена: 141480.00 T
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Описание:

"G-Protein-Coupled Receptors: Signaling, Trafficking, and Regulation," a new volume in the "Methods in Cell Biology" series continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in G-Protein-Coupled Receptors, and includes sections on such topics signaling, trafficking and regulation.
Covers the increasingly appreciated cell biology field of G-protein-coupled receptorsIncludes both established and new technologiesContributed by experts in the fieldCovers topics such as signaling, trafficking, and regulation

G Protein-Coupled Receptors: From Structure to Function

Название: G Protein-Coupled Receptors: From Structure to Function
ISBN: 1849731837 ISBN-13(EAN): 9781849731836
Издательство: Royal Society of Chemistry
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Цена: 239350.00 T
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Описание: This book considers the relationship between structure and function in G protein-coupled receptors (GPCRs) and the implications for drug design.

Nuclear G-Protein Coupled Receptors

Автор: Bruce G. Allen; Terence E. H?bert
Название: Nuclear G-Protein Coupled Receptors
ISBN: 1493955462 ISBN-13(EAN): 9781493955466
Издательство: Springer
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Цена: 88500.00 T
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Описание: Nuclear G-Protein Coupled Receptors: Methods and Protocols is a compilation of a number of conceptual and methodological aspects important for the validation and characterization of intacrine signaling systems.

From Structure To Clinical Development: Allosteric Modulation Of G Protein-Coupled Receptors,88

Автор: Langmead, Christopher J.
Название: From Structure To Clinical Development: Allosteric Modulation Of G Protein-Coupled Receptors,88
ISBN: 0128201878 ISBN-13(EAN): 9780128201879
Издательство: Elsevier Science
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Цена: 213350.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo‐switchable allosteric ligands, Computational approaches for the design of mGlu receptor allosteric modulators, Allosteric modulation of GLP‐1 receptor in metabolic disorders, Group II mGluR roles in the nervous system and their roles in addiction, RAMPs as allosteric modulators of Class B GPCRs, Structure‐based discovery and development of mGlu5 NAMs, and much more.

G Protein-Coupled Receptors - Modeling and Simulation

Автор: Marta Filizola
Название: G Protein-Coupled Receptors - Modeling and Simulation
ISBN: 9400774222 ISBN-13(EAN): 9789400774223
Издательство: Springer
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Цена: 148020.00 T
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Описание: G protein-coupled receptors (GPCRs) are heptahelical transmembrane receptors that convert extra-cellular stimuli into intra-cellular signaling, and ultimately into biological responses.

G Protein-Coupled Receptors

Название: G Protein-Coupled Receptors
ISBN: 0367392372 ISBN-13(EAN): 9780367392376
Издательство: Taylor&Francis
Рейтинг:
Цена: 65320.00 T
Наличие на складе: Невозможна поставка.
Описание: With contributions from international experts in the fields of pharmacology, neuroscience, and biochemistry, this text provides an in-depth exploration of GPCRs. Coverage includes the screening of ligands for GPCRs, physiological and molecular characterizations of GPCRs, and structures of GPCRs and their ligands. The book explores current research issues in the post-genome era, particularly the identification of endogenous ligands that may lead to finding new hormones or neurotransmitters. It also discusses the determination of the tertiary structure of GPCRs, useful for understanding GPCR interactions and for the theoretical modeling of drugs.

Oligomerization In Health And Disease: From Enzymes To G Protein-Coupled Receptors,169

Автор: Giraldo, Jesus
Название: Oligomerization In Health And Disease: From Enzymes To G Protein-Coupled Receptors,169
ISBN: 0128179295 ISBN-13(EAN): 9780128179291
Издательство: Elsevier Science
Рейтинг:
Цена: 140360.00 T
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Описание:

Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors, Volume 169 in the Progress in Molecular Biology and Translational Science series, provides in-depth reviews on topics of exceptional scientific importance. Topics of note in this new release include Computational prediction and re-design of aberrant oligomerization, Oligomerization of G protein-coupled receptors: an historical overview, Prediction and targeting of GPCR oligomer interfaces, GPCR Oligomerization dynamics: Functional consequences, GPCR heteromerization in neuropsychiatric disorders, Structural basis of regulation and oligomerization of human cystathionine β-synthase, and Oligomerization of Porphobilinogen Synthase.

G-Protein-Coupled Receptor Dimers

Автор: Katharine Herrick-Davis; Graeme Milligan; Giuseppe
Название: G-Protein-Coupled Receptor Dimers
ISBN: 3319601725 ISBN-13(EAN): 9783319601724
Издательство: Springer
Рейтинг:
Цена: 186330.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: G-protein-coupled receptors (GPCRs) are believed to be the largest family of membrane proteins involved in signal transduction and cellular responses.

G Protein-Coupled Receptor Genetics

Автор: Craig W. Stevens
Название: G Protein-Coupled Receptor Genetics
ISBN: 1493963325 ISBN-13(EAN): 9781493963324
Издательство: Springer
Рейтинг:
Цена: 111790.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: G Protein-Coupled Receptor Genetics: Research and Methods in the Post-Genomic Era features practical techniques inspired by the fast moving GPCR field.

G Protein-Coupled Receptor Signaling in Plants

Автор: Mark P. Running
Название: G Protein-Coupled Receptor Signaling in Plants
ISBN: 1493962167 ISBN-13(EAN): 9781493962167
Издательство: Springer
Рейтинг:
Цена: 97820.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology book describes techniques used in the study of small GTPases and related proteins. Includes a chapter on bioinformatics approaches, plus reproducible protocols, materials lists, practical tips and troubleshooting advice.

G Protein-Coupled Receptor Genetics

Автор: Craig W. Stevens
Название: G Protein-Coupled Receptor Genetics
ISBN: 1627037780 ISBN-13(EAN): 9781627037785
Издательство: Springer
Рейтинг:
Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: G Protein-Coupled Receptor Genetics: Research and Methods in the Post-Genomic Era features practical techniques inspired by the fast moving GPCR field.


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