Gabab Receptor Pharmacology: A Tribute To Norman Bowery,58, Blackburn, Thomas

Автор: Bowery Norman G
Название: Allosteric Receptor Modulation In Drug Targeting
ISBN: 0824727916 ISBN-13(EAN): 9780824727918
Издательство: Taylor&Francis
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Цена: 193950.00 T
Наличие на складе: Невозможна поставка.
Описание: Allosteric Receptor Modulation in Drug Targeting

Автор: Colombo Giancarlo
Название: Gabab Receptor
ISBN: 3319834282 ISBN-13(EAN): 9783319834283
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: An up-to-date comprehensive overview of the GABA B receptor system with a particular focus on the most recent therapeutic applications and potential. This receptor system has recently been implicated in several diseases and disorders including gastroesophageal reflux disease, epilepsy, mood disorders, depression, and alcohol and substance use disorder. The authors, leading researchers in the field, explore a number of approaches, including medicinal chemistry, molecular biology, physiology, and preclinical and clinical pharmacology. This overview provides a translational perspective on the potential of the GABA B receptor pharmacology.

Автор: Chikako Tanaka; Norman G. Bowery
Название: GABA: Receptors, Transporters and Metabolism
ISBN: 3034898584 ISBN-13(EAN): 9783034898584
Издательство: Springer
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Цена: 97820.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.

Автор: T. Kenakin; J. A. Angus
Название: The Pharmacology of Functional, Biochemical, and Recombinant Receptor Systems
ISBN: 3642630286 ISBN-13(EAN): 9783642630286
Издательство: Springer
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Цена: 121890.00 T
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Описание: With contributions by numerous experts

Автор: Foreman J.
Название: Textbook of Receptor Pharmacology
ISBN: 0849310296 ISBN-13(EAN): 9780849310294
Издательство: Taylor&Francis
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Цена: 87790.00 T
Наличие на складе: Нет в наличии.
Описание: The bestselling first edition of Textbook of Receptor Pharmacology originated from a renowned course in receptor pharmacology taught at the University College of London for the past three decades. Its innovative format united four major approaches to the study of receptors: molecular biology, quantitative functional studies of agonists and antagonists, ligand binding, and signal transduction systems. The second edition builds on this foundation.This edition streamlines the material and focuses on cell membrane receptors along with their immediate signal transducers. The section on the molecular structure of receptors reflects the advances in this area. This edition also includes two restructured new chapters, one on G-proteins and one on tyrosine kinases, as signal transductors. Several chapters also contain problems for students to solve as well as worked-out solutions.The book contains over one hundred useful diagrams and tables to aid illustration of concepts and a helpful appendix explaining the simple mathematics used in the text. A time-saving resource and comprehensive textbook, Textbook of Receptor Pharmacology, Second Edition provides in-depth, up-to-date coverage of this

Автор: Emily M. Jutkiewicz
Название: Delta Opioid Receptor Pharmacology and Therapeutic Applications
ISBN: 303006980X ISBN-13(EAN): 9783030069803
Издательство: Springer
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Цена: 107130.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds and therapies used to modulate the DOR system. Part 2 describes new insights into the localization and trafficking of the DOR and how ligand-directed signaling alters the fate of the receptor. Part 3 concentrates on the potential role of the DOR system in disease states, such as pain, mood, addiction, and Parkinson’s disease. Throughout the book, the DOR system as a target for drug development will be discussed.

Автор: Jutkiewicz
Название: Delta Opioid Receptor Pharmacology and Therapeutic Applications
ISBN: 3319951319 ISBN-13(EAN): 9783319951317
Издательство: Springer
Рейтинг:
Цена: 107130.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds and therapies used to modulate the DOR system. Part 2 describes new insights into the localization and trafficking of the DOR and how ligand-directed signaling alters the fate of the receptor. Part 3 concentrates on the potential role of the DOR system in disease states, such as pain, mood, addiction, and Parkinson’s disease. Throughout the book, the DOR system as a target for drug development will be discussed.

Автор: Ehlert Frederick J
Название: Affinity And Efficacy: The Components Of Drug-Receptor Interactions
ISBN: 9814322563 ISBN-13(EAN): 9789814322560
Издательство: World Scientific Publishing
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Цена: 253440.00 T
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Описание: The interaction of a drug with a receptor encodes a vector of information having components of affinity and efficacy. This book describes how to analyze various responses to estimate the affinity and efficacy components of the initial drug-receptor interaction.

Автор: Xia Ying
Название: Neural Functions of the Delta-Opioid Receptor
ISBN: 3319798014 ISBN-13(EAN): 9783319798011
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is the first to summarize the progress of research on neural functions of the the delta opioid receptor (DOR) to date. This receptor, a member of the opioid receptor family, was traditionally thought to be primarily involved in pain modulation. Recent new findings have shown its unique role in neuroprotection and many other functions. Many scientists from a number of independent laboratories have now confirmed that DOR can provide neuroprotection against hypoxic/ischemic injuries. They have also found that it plays a role in a variety of physiological and pathophysiological events such as hypoxic encephalopathy, epilepsy, acupuncture, Parkinson's disease, etc. by regulating ionic homeostasis, glutamate transportation and signaling, and balancing intracellular survival/death signals. The book will provide a comprehensive overview of the current state of DOR research and provide a blueprint for future directions.

Автор: Bernd Nilius; Veit Flockerzi
Название: Mammalian Transient Receptor Potential (TRP) Cation Channels
ISBN: 3662512238 ISBN-13(EAN): 9783662512234
Издательство: Springer
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Цена: 330870.00 T
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Описание: This book offers up-to-date information on the molecular and functional properties and pharmacology of mammalian Transient Receptor Potential channels, from close-up views of single protein/channels to broader principles of function and important pathologies.

Автор: Robert B. Raffa
Название: Drug-Receptor Thermodynamics: Introduction and Applications
ISBN: 0471720429 ISBN-13(EAN): 9780471720423
Издательство: Wiley
Рейтинг:
Цена: 507880.00 T
Наличие на складе: Поставка под заказ.
Описание: "Drug-Receptor Thermodynamics" covers the general principles of thermodynamics and its use and utility in pharmacology; provides a review of actual applications arranged according to receptor categories; and discusses the potential for thermodynamics to some day predict drug action.

Автор: Mario Tiberi
Название: Dopamine Receptor Technologies
ISBN: 149394889X ISBN-13(EAN): 9781493948895
Издательство: Springer
Рейтинг:
Цена: 102480.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: To foster a better understanding of dopamine receptor functionality, this detailed volume creates an interface between updated classical methods and new emerging technologies heretofore not available to new or seasoned researchers.