Автор: Blackburn, Thomas Название: Gabab Receptor Pharmacology: A Tribute To Norman Bowery,58 ISBN: 0123786479 ISBN-13(EAN): 9780123786470 Издательство: Elsevier Science Рейтинг: Цена: 185270.00 T Наличие на складе: Поставка под заказ. Описание: A monograph that provides a perspective of current research, both basic and translational in the discovery of drugs acting at the GABAB receptor. It includes articles written by investigators in the field. It informs on the various developments.
Автор: Kim Neve Название: Functional Selectivity of G Protein-Coupled Receptor Ligands ISBN: 1493961160 ISBN-13(EAN): 9781493961160 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In Functional Selectivity of G Protein-Coupled Receptors, experts review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon.
Автор: Jutkiewicz Название: Delta Opioid Receptor Pharmacology and Therapeutic Applications ISBN: 3319951319 ISBN-13(EAN): 9783319951317 Издательство: Springer Рейтинг: Цена: 107130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds and therapies used to modulate the DOR system. Part 2 describes new insights into the localization and trafficking of the DOR and how ligand-directed signaling alters the fate of the receptor. Part 3 concentrates on the potential role of the DOR system in disease states, such as pain, mood, addiction, and Parkinson’s disease. Throughout the book, the DOR system as a target for drug development will be discussed.
Автор: Gabriela K. Popescu Название: Ionotropic Glutamate Receptor Technologies ISBN: 1493948954 ISBN-13(EAN): 9781493948956 Издательство: Springer Рейтинг: Цена: 88500.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This detailed volume explores key technologies that are used currently to investigate iGluR structure, function and physiology.
Автор: Gerard Pasterkamp Название: Semaphorins: Receptor and Intracellular Signaling Mechanisms ISBN: 1441924272 ISBN-13(EAN): 9781441924278 Издательство: Springer Рейтинг: Цена: 213360.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book details our progress in understanding the receptor and intracellular signaling mechanisms utilized by semaphorins. The comprehensive overview of semaphorin biology and signaling presented in this book allows one to compare semaphorin functions between different biological systems.
Автор: Wang Yizheng Название: Transient Receptor Potential Canonical Channels and Brain Diseases ISBN: 940241486X ISBN-13(EAN): 9789402414868 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Поставка под заказ. Описание: This book discusses the latest findings on the physiological and pathological functions of transient receptor potential canonical/classical (TRPC) proteins in the brain. In addition to reviewing the functions of TRPCs in brain development and neuron transmission, it mainly covers the potential roles of TRPCs in brain disorders.
Автор: Eva Sykova Название: Ionic and Volume Changes in the Microenvironment of Nerve and Receptor Cells ISBN: 364276939X ISBN-13(EAN): 9783642769399 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The close proximity of the neuronal elements in the CNS and the narrowness of the intercellular spaces provides a basis not only for interaction between the elements themselves, but also between the elements and their microenvironment.
Автор: Katharine Herrick-Davis; Graeme Milligan; Giuseppe Название: G-Protein-Coupled Receptor Dimers ISBN: 3319867954 ISBN-13(EAN): 9783319867953 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Поставка под заказ. Описание: G-protein-coupled receptors (GPCRs) are believed to be the largest family of membrane proteins involved in signal transduction and cellular responses.
Автор: Curtis A. Machida Название: Adrenergic Receptor Protocols ISBN: 1489941568 ISBN-13(EAN): 9781489941565 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Adrenergic Receptor Protocols consists of 35 chapters dealing with va- ous aspects of adrenergic receptor analyses, including the use of genetic, RNA, protein expression, transactivator, second messenger, immunocytochemical, electrophysiological, transgenic, and in situ hybridization approaches.
Автор: Li Название: Nicotinic Acetylcholine Receptor Technologies ISBN: 1493937669 ISBN-13(EAN): 9781493937660 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume provides properties, biological function, methods,and approaches for manipulating nAChRs in different organisms. NicotinicAcetylcholine Receptor Technologies guides readers through moleculartechniques and behavioral tests used to investigate nicotinic drugs,chronoamperometry, emerging technologies and methods for the analysis ofnAChRs, single nucleotide polymorphism (SNP), fluorescence techniques, spectralconfocal, allosteric modulators of a7-nAChRs, and a comprehensive evolutionalrelation for most nAChR subunits, in both vertebrate and invertebrate species.Written for the popular Neuromethods series, chapters include thekind of detail and key implementation advice that ensures successful results inthe laboratory. Authoritative and practical, Nicotinic AcetylcholineReceptor Technologies aims to ensure successful results in thefurther study of this vital field.
Автор: Alfred Maelicke Название: Nicotinic Acetylcholine Receptor ISBN: 3642716512 ISBN-13(EAN): 9783642716515 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of the NATO Advanced Research Workshop on Mechanism of Action of the Nicotinic Acetylcholine Receptors held on the Island of Santorini, Greece, May 19-23, 1986
Автор: Jeanelle Portelli; Ilse Smolders Название: Central Functions of the Ghrelin Receptor ISBN: 1493955349 ISBN-13(EAN): 9781493955343 Издательство: Springer Рейтинг: Цена: 130590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The Ghrelin receptor was identified before its natural ligand ghrelin.
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