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Biomarkers in Cancer Therapy, Hideaki Shimada


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Автор: Hideaki Shimada
Название:  Biomarkers in Cancer Therapy
ISBN: 9789811372971
Издательство: Springer
Классификация:
ISBN-10: 9811372977
Обложка/Формат: Soft cover
Страницы: 157
Вес: 0.32 кг.
Дата издания: 2019
Язык: English
Издание: 1st ed. 2019
Иллюстрации: 30 tables, color; 17 illustrations, color; 5 illustrations, black and white; viii, 157 p. 22 illus., 17 illus. in color.; 30 tables, color; 17 illustrations, color; 5 illustrations, black and white; viii, 157 p. 22 illus., 17 illus. in color.
Размер: 235 x 155
Читательская аудитория: Professional & vocational
Основная тема: Oncology
Подзаголовок: Liquid Biopsy Comes of Age
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This book sheds new light on research into liquid biopsy biomarkers for cancer screening. The chapters in the first half address exosomes, circulating cell-free DNA and autoantibodies, and main solid cancers, along with companion biomarkers – all of which serve as the basis for exploring key research questions for future clinical trials in the book’s second half. The study of biomarkers has evolved rapidly thanks to advances in precision medicine. While conventional cancer biomarker research is focused on proteomics or gene analysis of resected tissue, diagnostic markers have since become significant in terms of gauging the effectiveness of molecularly targeted drugs or the likelihood of a favorable prognosis. In addition, conventional treatment strategy, which draws on archives of resected tissue samples, is now gradually being replaced by monitoring with the use of liquid biopsy, which is poised to become the new mainstream in molecular targeting therapy. The contributing authors discuss in detail biomarkers, molecular targets for treatment, monitoring markers to evaluate treatment responses, prognostic markers, and screening and early diagnosis. Accordingly, this excellent collection of texts will benefit not only oncologists, but also medical and biological researchers and pharmaceutical scientists involved in the latest cancer research.
Дополнительное описание: I. General Statement.- 1.Exosomes.- 2.Cell Free DNA.- 3.Autoantibody.- 4.Serum Protein.- Part II. Application to Each Cancer.- 5.Head and Neck Cancer / Esophageal Cancer.- 6.Gastric Cancer.- 7.Colorectal Cancer.- 8.Liver Cancer.- 9.Pancreas Cancer.- 10.Lu


Novel biomarkers in the continuum of breast cancer

Название: Novel biomarkers in the continuum of breast cancer
ISBN: 3319229087 ISBN-13(EAN): 9783319229089
Издательство: Springer
Рейтинг:
Цена: 130610.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides a comprehensive review of established and novel biomarkers across the continuum of breast cancer.

Biomarkers for Immunotherapy of Cancer

Автор: Magdalena Thurin; Alessandra Cesano; Francesco M.
Название: Biomarkers for Immunotherapy of Cancer
ISBN: 1493997750 ISBN-13(EAN): 9781493997756
Издательство: Springer
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Цена: 144410.00 T
Наличие на складе: Поставка под заказ.
Описание: This book provides the immune oncology (IO) community with a deeper understanding of the scope of the biomarker methods to potentially improve the outcome from immunotherapy.

Biomarkers of Kidney Disease

Автор: Edelstein, Charles L.
Название: Biomarkers of Kidney Disease
ISBN: 0128030143 ISBN-13(EAN): 9780128030141
Издательство: Elsevier Science
Рейтинг:
Цена: 97690.00 T
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Описание:

Biomarkers of Kidney Disease, Second Edition, focuses on the basic and clinical research of biomarkers in common kidney diseases, detailing the characteristics of an ideal biomarker. The latest techniques for biomarker detection, including metabolomics and proteomics are covered in the book.

This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical analysis, transplantation, and preeclampsia. New chapters include biomarkers of cardiovascular disease in patients with CKD, biomarkers of Polycystic Kidney Disease, and biomarkers and the role of nanomedicine.


Biomarkers in Cancer Therapy

Автор: Shimada
Название: Biomarkers in Cancer Therapy
ISBN: 9811372942 ISBN-13(EAN): 9789811372940
Издательство: Springer
Рейтинг:
Цена: 83850.00 T
Наличие на складе: Поставка под заказ.

Biomarkers in neoplastic neuropathology

Автор: Rodriguez, Fausto J. Ho, Cheng-ying
Название: Biomarkers in neoplastic neuropathology
ISBN: 3319209302 ISBN-13(EAN): 9783319209302
Издательство: Springer
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Цена: 83850.00 T
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Описание: This book is a rich source of information on biomarkers applicable to the pathology of neoplastic disorders of the brain. Thorough descriptions are provided of the techniques currently available for clinical and experimental evaluation of biomarkers in brain neoplasms, including in situ hybridization, array-based methods, methylation profiling, next-generation sequencing, and practical gene panels. Incorporation of multiple biomarkers in the development of molecular subgroups with biologic and therapeutic relevance is also discussed. A section on biobanking covers the equally important topic of optimal preservation of tissue and includes consideration of ethical considerations raised by the use of tissue obtained in clinical settings. The closing section discusses the major categories of neoplastic disorders involving the nervous system, with emphasis on diagnostic, prognostic, and predictive biomarkers used in the pathologic evaluation of different types of brain tumor.

Biomarkers in Breast Cancer

Автор: Giampietro Gasparini; Daniel F. Hayes
Название: Biomarkers in Breast Cancer
ISBN: 1617374369 ISBN-13(EAN): 9781617374364
Издательство: Springer
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Цена: 231990.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators.

Cancer Biomarkers: Developments, Applications and Therapies

Автор: Miles Karen
Название: Cancer Biomarkers: Developments, Applications and Therapies
ISBN: 1632413949 ISBN-13(EAN): 9781632413949
Издательство: Неизвестно
Цена: 166240.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.

Cancer Biomarkers in Body Fluids

Автор: Dakubo
Название: Cancer Biomarkers in Body Fluids
ISBN: 3319015796 ISBN-13(EAN): 9783319015798
Издательство: Springer
Рейтинг:
Цена: 167700.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The molecular and genetic signatures of cancer are represented in the peripheral circulation and other body fluids, giving rise to the “liquid biopsy” concept. This new paradigm of molecular profiling of cancer cells offers several advantages over traditional tissue biopsy. It is convenient, noninvasive, conforms to current clinical practice, enables real time disease monitoring and the study of tumor evolution, can easily be sampled multiple times, and this sample is more representative of the heterogeneous cancer cells than biopsy sampling. Indeed, all aspects of cancer molecular genetic information, stemming from DNA (both nuclear and mitochondria), RNA (coding and noncoding), peptides and proteins, metabolites and lipids are present in body fluids as free, cell surface bound or enclosed in membrane vesicles, and are being harnessed for disease management. Additionally, circulating tumor, and tumor stem cells provide prognostic information, and also enable the study of the intricate molecular processes associated with metastasis and drug resistance. This treatise deals with the general principles of the molecular pathology of cancer, and its associated imprints in circulation. The transitional process from discovery, prototype development, translational research, to product development can be complex and costly. The critical path to biomarker development and qualification for successful use in drug development is detailed herein as well.This book is of interest to Cancer Researchers, Oncologists, Clinicians, Surgeons, Medical Students, Nurses, Diagnostic Laboratories, and Pharmaceutical Industries.??

Advances in Cancer Biomarkers

Автор: Roberto Scatena
Название: Advances in Cancer Biomarkers
ISBN: 9402404201 ISBN-13(EAN): 9789402404203
Издательство: Springer
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Цена: 156720.00 T
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Описание:

Prelims.- I Generality.- II Tumor markers-a critical revision.- Enzymes.- Hormones.- Oncofetal proteins.- Cytokeratins.- Carbohydrate markers.- Blood group antigens.- Genetic markers.- Various protein markers.- III Perspectives.- The role of Circulating tumor Cells as tumor markers.- Index.


Cancer Biomarkers in Body Fluids: Principles

Автор: Dakubo Gabriel D.
Название: Cancer Biomarkers in Body Fluids: Principles
ISBN: 331979129X ISBN-13(EAN): 9783319791296
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The molecular and genetic signatures of cancer are represented in the peripheral circulation and other body fluids, giving rise to the “liquid biopsy” concept. This new paradigm of molecular profiling of cancer cells offers several advantages over traditional tissue biopsy. It is convenient, noninvasive, conforms to current clinical practice, enables real time disease monitoring and the study of tumor evolution, can easily be sampled multiple times, and this sample is more representative of the heterogeneous cancer cells than biopsy sampling. Indeed, all aspects of cancer molecular genetic information, stemming from DNA (both nuclear and mitochondria), RNA (coding and noncoding), peptides and proteins, metabolites and lipids are present in body fluids as free, cell surface bound or enclosed in membrane vesicles, and are being harnessed for disease management. Additionally, circulating tumor, and tumor stem cells provide prognostic information, and also enable the study of the intricate molecular processes associated with metastasis and drug resistance. This treatise deals with the general principles of the molecular pathology of cancer, and its associated imprints in circulation. The transitional process from discovery, prototype development, translational research, to product development can be complex and costly. The critical path to biomarker development and qualification for successful use in drug development is detailed herein as well. This book is of interest to Cancer Researchers, Oncologists, Clinicians, Surgeons, Medical Students, Nurses, Diagnostic Laboratories, and Pharmaceutical Industries.

Novel Biomarkers in the Continuum of Breast Cancer

Автор: Stearns Vered
Название: Novel Biomarkers in the Continuum of Breast Cancer
ISBN: 3319794345 ISBN-13(EAN): 9783319794341
Издательство: Springer
Рейтинг:
Цена: 93160.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides a comprehensive review of established and novel biomarkers across the continuum of breast cancer.

Cancer Biomarkers

Название: Cancer Biomarkers
ISBN: 1578087619 ISBN-13(EAN): 9781578087617
Издательство: Taylor&Francis
Рейтинг:
Цена: 153120.00 T
Наличие на складе: Невозможна поставка.
Описание: This unique synthesis of chapters from top experts in their fields targets the essential area of cancer biomarkers and the need for better and more rigorous design and clinical trials.


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