Novel Biomarkers in the Continuum of Breast Cancer, Stearns Vered
Название: Cancer Biomarkers ISBN: 1578087619 ISBN-13(EAN): 9781578087617 Издательство: Taylor&Francis Рейтинг: Цена: 153120.00 T Наличие на складе: Невозможна поставка. Описание: This unique synthesis of chapters from top experts in their fields targets the essential area of cancer biomarkers and the need for better and more rigorous design and clinical trials.
Автор: Edelstein, Charles L. Название: Biomarkers of Kidney Disease ISBN: 0128030143 ISBN-13(EAN): 9780128030141 Издательство: Elsevier Science Рейтинг: Цена: 97690.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Biomarkers of Kidney Disease, Second Edition, focuses on the basic and clinical research of biomarkers in common kidney diseases, detailing the characteristics of an ideal biomarker. The latest techniques for biomarker detection, including metabolomics and proteomics are covered in the book.
This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical analysis, transplantation, and preeclampsia. New chapters include biomarkers of cardiovascular disease in patients with CKD, biomarkers of Polycystic Kidney Disease, and biomarkers and the role of nanomedicine.
Название: Novel biomarkers in the continuum of breast cancer ISBN: 3319229087 ISBN-13(EAN): 9783319229089 Издательство: Springer Рейтинг: Цена: 130610.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume provides a comprehensive review of established and novel biomarkers across the continuum of breast cancer.
Endocrine Biomarkers: Clinical Aspects and Laboratory Determination covers all the pre-analytical variables that can affect test results, both in the clinic and laboratory. Biomarkers of endocrine and bone diseases are discussed from both clinical and laboratory perspectives, and the authors elaborate on the teamwork-based app+roach between the clinician and the laboratory professional in the diagnosis and management of endocrine and bone disorders.
Discussions include test utilization, laboratory measurement methods, harmonization and standardization, interpretation of results, and reference intervals. Each chapter ends with a discussion of one or two relevant cases with shared opinions from both a clinician and a clinical chemist. Each chapter also includes a summary box outlining key points and common pitfalls in the use of specific disease biomarkers and tests.
Автор: Giampietro Gasparini; Daniel F. Hayes Название: Biomarkers in Breast Cancer ISBN: 1617374369 ISBN-13(EAN): 9781617374364 Издательство: Springer Рейтинг: Цена: 231990.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators.
Автор: Rodriguez, Fausto J. Ho, Cheng-ying Название: Biomarkers in neoplastic neuropathology ISBN: 3319209302 ISBN-13(EAN): 9783319209302 Издательство: Springer Рейтинг: Цена: 83850.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book is a rich source of information on biomarkers applicable to the pathology of neoplastic disorders of the brain. Thorough descriptions are provided of the techniques currently available for clinical and experimental evaluation of biomarkers in brain neoplasms, including in situ hybridization, array-based methods, methylation profiling, next-generation sequencing, and practical gene panels. Incorporation of multiple biomarkers in the development of molecular subgroups with biologic and therapeutic relevance is also discussed. A section on biobanking covers the equally important topic of optimal preservation of tissue and includes consideration of ethical considerations raised by the use of tissue obtained in clinical settings. The closing section discusses the major categories of neoplastic disorders involving the nervous system, with emphasis on diagnostic, prognostic, and predictive biomarkers used in the pathologic evaluation of different types of brain tumor.
Автор: Dakubo Название: Cancer Biomarkers in Body Fluids ISBN: 3319015796 ISBN-13(EAN): 9783319015798 Издательство: Springer Рейтинг: Цена: 167700.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The molecular and genetic signatures of cancer are represented in the peripheral circulation and other body fluids, giving rise to the “liquid biopsy” concept. This new paradigm of molecular profiling of cancer cells offers several advantages over traditional tissue biopsy. It is convenient, noninvasive, conforms to current clinical practice, enables real time disease monitoring and the study of tumor evolution, can easily be sampled multiple times, and this sample is more representative of the heterogeneous cancer cells than biopsy sampling. Indeed, all aspects of cancer molecular genetic information, stemming from DNA (both nuclear and mitochondria), RNA (coding and noncoding), peptides and proteins, metabolites and lipids are present in body fluids as free, cell surface bound or enclosed in membrane vesicles, and are being harnessed for disease management. Additionally, circulating tumor, and tumor stem cells provide prognostic information, and also enable the study of the intricate molecular processes associated with metastasis and drug resistance. This treatise deals with the general principles of the molecular pathology of cancer, and its associated imprints in circulation. The transitional process from discovery, prototype development, translational research, to product development can be complex and costly. The critical path to biomarker development and qualification for successful use in drug development is detailed herein as well.This book is of interest to Cancer Researchers, Oncologists, Clinicians, Surgeons, Medical Students, Nurses, Diagnostic Laboratories, and Pharmaceutical Industries.??
Автор: Dakubo Gabriel D. Название: Cancer Biomarkers in Body Fluids: Biomarkers in Circulation ISBN: 3319839217 ISBN-13(EAN): 9783319839219 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: 1. Melanoma Biomarkers in Circulation. - 2. Head and Neck Cancer Biomarkers in Circulation. - 3. Lung Cancer Biomarkers in Circulation. - 4. Breast Cancer Biomarkers in Circulation. - 5. Esophageal Cancer Biomarkers in Circulation. - 6. Gastric Cancer Biomarkers in Circulation. - 7. Colorectal Cancer Biomarkers in Circulation. - 8. Hepatocellular Carcinoma Biomarkers in Circulation. - 9. Pancreatic Cancer Biomarkers in Circulation. - 10. Renal Cell Carcinoma Biomarkers in Circulation. - 11. Urothelial Bladder Cancer Biomarkers in Circulation. - 12. Prostate Cancer Biomarkers in Circulation. - 13. Ovarian Cancer Biomarkers in Circulation. - 14. Endometriosis Biomarkers in Body Fluids. - 15. Endometrial Cancer Biomarkers in Circulation. - 16. Cervical Cancer Biomarkers in Circulation. - 17. Endocrine Cancer Biomarkers in Circulation. - 18. Brain Tumor Biomarkers in Circulation.
Автор: Shimada Название: Biomarkers in Cancer Therapy ISBN: 9811372942 ISBN-13(EAN): 9789811372940 Издательство: Springer Рейтинг: Цена: 83850.00 T Наличие на складе: Поставка под заказ.
Автор: Dakubo Gabriel D. Название: Cancer Biomarkers in Body Fluids: Principles ISBN: 331979129X ISBN-13(EAN): 9783319791296 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The molecular and genetic signatures of cancer are represented in the peripheral circulation and other body fluids, giving rise to the “liquid biopsy” concept. This new paradigm of molecular profiling of cancer cells offers several advantages over traditional tissue biopsy. It is convenient, noninvasive, conforms to current clinical practice, enables real time disease monitoring and the study of tumor evolution, can easily be sampled multiple times, and this sample is more representative of the heterogeneous cancer cells than biopsy sampling. Indeed, all aspects of cancer molecular genetic information, stemming from DNA (both nuclear and mitochondria), RNA (coding and noncoding), peptides and proteins, metabolites and lipids are present in body fluids as free, cell surface bound or enclosed in membrane vesicles, and are being harnessed for disease management. Additionally, circulating tumor, and tumor stem cells provide prognostic information, and also enable the study of the intricate molecular processes associated with metastasis and drug resistance. This treatise deals with the general principles of the molecular pathology of cancer, and its associated imprints in circulation. The transitional process from discovery, prototype development, translational research, to product development can be complex and costly. The critical path to biomarker development and qualification for successful use in drug development is detailed herein as well. This book is of interest to Cancer Researchers, Oncologists, Clinicians, Surgeons, Medical Students, Nurses, Diagnostic Laboratories, and Pharmaceutical Industries.
Автор: Dakubo Название: Cancer Biomarkers in Body Fluids ISBN: 3030247236 ISBN-13(EAN): 9783030247232 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Поставка под заказ. Описание: The ability to measure and monitor cancer biomarkers in "body fluid biopsy" should greatly impact oncologic practice. "Biomarkers in Proximal Fluids", the third of the "Cancer Biomarkers in Body Fluids" series details cancer signatures in none or minimally circulating body fluids including saliva, sputum, bronchoalveolar lavage fluid, exhaled breath condensate, nipple aspirate fluid, gastric and pancreatic juice, stool, urine, and prostatic, peritoneal and cerebrospinal fluid. These fluids are enriched with biomarkers, especially those emanating from cells of the proximal tissue.
Chapter 1 examines the global burden of cancer and the need for regional efforts at primary prevention, early detection and patient care. Chapters 2-12 address tissue-specific biomarkers in associated body fluids. The tumor interstitial fluid as a microenvironment rich in cancer biomarkers is detailed in chapter 13, while chapter 14 looks at the human body fluid microbiome and its evolving role in cancer.
Commercially available assays using proximal fluids are examined at the end of the respective chapters. This book complements its predecessors and is equally useful to oncologists, cancer researchers, clinicians, medical students, nurses, diagnostic laboratory and pharmaceutical industry personnel.
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