Cell Reprogramming for Immunotherapy, Samuel G. Katz; Peter M. Rabinovich
Автор: Donnadieu Название: Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy ISBN: 3319422219 ISBN-13(EAN): 9783319422213 Издательство: Springer Рейтинг: Цена: 139310.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.
The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.
Автор: Donnadieu Emmanuel Название: Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy ISBN: 3319825283 ISBN-13(EAN): 9783319825281 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers.
Автор: Samuel G. Katz; Peter M. Rabinovich Название: Cell Reprogramming for Immunotherapy ISBN: 1071602020 ISBN-13(EAN): 9781071602027 Издательство: Springer Рейтинг: Цена: 144410.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume details key protocols for developing strategies in immunotherapy. Chapters guide the readers through protocols related to various DNA, RNA and protein methods to reprogram the immune system, immune cells, analyzing the effect of the reprogrammed cells, and key methods to consider and analyze patients enrolled in clinical trials with novel immunotherapy regimens. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cell Reprogramming for Immunotherapy: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Автор: Butterfield Lisa H., Kaufman Howard L., Marincola Francesco M. Название: Cancer Immunotherapy Principles and Practice ISBN: 1620700972 ISBN-13(EAN): 9781620700976 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 238260.00 T Наличие на складе: Нет в наличии. Описание: Cancer Immunotherapy Principles and Practice, from the Society of Immunotherapy of Cancer (SITC), is the authoritative reference on cancer immunobiology and the immunotherapy treatments that harness the immune system to combat malignant disease.Featuring five sections and over 50 chapters covering the Basic Principles of Tumor Immunology, Cancer Immunotherapy Targets and Classes, Immune Function in Cancer Patients, Disease Specific Treatments and Outcomes, and Regulatory Aspects of Cancer Immunotherapy, this book covers all major topics that have shaped the development of immunotherapy and propelled it to its current place at the forefront of cancer treatment innovation. This volume is a comprehensive resource for oncologists and fellows, immunologists, cancer researchers, and related practitioners seeking understanding of the basic science and clinical applications of cancer immunotherapy. As well as presenting the evidence for immune-based cancer treatment, it positions immunotherapy in the context of other available cancer treatments and provides data on response rates, risks, and toxicities across a variety of diseases. Filled with detailed tables, and instructive illustrations, as well as key points for quick reference, Cancer Immunotherapy Principles and Practice simplifies a challenging and dynamic subject.Key Features:Clearly summarizes the basic principles and research supporting cancer immunotherapy clinical translationContains expert guidance and treatment strategies for all immunotherapy classes and agents, including cell-based therapies, monoclonal antibodies, cytokine therapies, checkpoint inhibitors, oncolytic viruses, adjuvant approaches, and treatment combinationsIncludes expert perspectives from leading authorities in the fieldProvides information on all FDA-approved immunotherapies, including clinical management and outcome dataDiscusses clinical aspects of immunotherapy for individual cancer types, including melanoma and other skin cancers, lung cancers, gynecologic cancers, gastrointestinal cancers, hematologic cancers, genitourinary cancers, head and neck cancers, sarcomas, brain and other CNS cancers, breast cancer, and pediatric malignancies.Explains regulatory aspects behind the development and approval of immunotherapy drugs Includes Online Access to the Digital Book
Автор: Rees Robert C. Название: Tumor Immunology and Immunotherapy ISBN: 0199676860 ISBN-13(EAN): 9780199676866 Издательство: Oxford Academ Рейтинг: Цена: 240240.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Tumor immunology and immunotherapy provides a comprehensive account of cancer immunity and immunotherapy. Examining recent results, current areas of interest and the specific issues that are affecting the research and development of vaccines, this book provides insight into how these problems may be overcome as viewed by leaders in the field.
Автор: Marc S. Ernstoff, Igor Puzanov, Caroline Robert, Adi M. Diab, Peter M. Hersey Название: SITC`s Guide to Immunotherapy Toxicity: Best Practices for Managing Side Effects of Cancer Treatment ISBN: 0826172148 ISBN-13(EAN): 9780826172143 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 45270.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A practical reference to managing side effects associated with FDA-approved cancer immunotherapy drugs. Part One contains chapter-based overviews of immune checkpoint inhibitors in the clinic. Part Two is structured by common and uncommon toxicities that affect major organ sites throughout the body.
Автор: Lopci, Egesta, Fanti, Stefano Название: Atlas of Response to Immunotherapy ISBN: 3030311120 ISBN-13(EAN): 9783030311124 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Поставка под заказ. Описание: This atlas is a concise but comprehensive guide to the diverse patterns of response to immunotherapy as observed on Positron Emission Tomography/Computed Tomography (PET/CT) and other conventional imaging modalities, including CT and Magnetic Resonance Imaging (MRI).
Автор: R.J.A. van Moorselaar; Frans M.J. Debruyne; Ronald Название: Immunotherapy of Renal Cell Carcinoma ISBN: 3540528350 ISBN-13(EAN): 9783540528357 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: With contributions by numerous experts
Автор: Balkhi Mumtaz Название: Basics of Chimeric Antigen Receptor (CAR) Immunotherapy ISBN: 0128195738 ISBN-13(EAN): 9780128195734 Издательство: Elsevier Science Рейтинг: Цена: 88690.00 T Наличие на складе: Поставка под заказ. Описание: Besides the ITIL(R) 4 Foundation Courseware - English (ISBN: 9789401803939) publication you are advised to obtain the publication ITIL(R) 4 - A Pocket Guide (ISBN: 978 94 018 0439 4).The course is designed as an introduction to ITIL 4 and enables you to understand a new way to look at IT Service Management through a Service Value System (SVS). ITIL 4 provides an end-to-end picture of what means to contribute to business value, and also integrates concepts from models such as Lean IT, Agile and DevOps.This course is for those who are involved in the delivery of IT services and need an understanding of best practice in IT Service Management. Student must pass a 60 minute, 40 question closed book multiple choice, examination with a passing score of 65% in order to receive this certification. You can write the exam at any time and at any place after the course. The test is done via your own computer proctored via webcam.Candidates wishing to be trained and pass the exam for this qualification would be recommended to have a general awareness of IT and appreciation of their own business environment.You`ll learn:¢ Understand the key concepts of service management¢ Understand how the ITIL guiding principles can help an organization adopt and adapt service management¢ Understand the four dimensions of service management¢ Understand the purpose and components of the ITIL service value system¢ Understand the activities of the service value chain, and how they interconnect¢ Know the purpose and key terms of 18 ITIL practices¢ Understand 7 ITIL practices
Автор: Aung Naing; Joud Hajjar Название: Immunotherapy ISBN: 3030025047 ISBN-13(EAN): 9783030025045 Издательство: Springer Рейтинг: Цена: 74530.00 T Наличие на складе: Поставка под заказ. Описание: The second edition of Immunotherapy is an updated overview of immuno-oncology in acute myleloid leukemia, non-small cell lung cancer and melanoma, showcasing advances in the management of cancer broadly classified as hematological malignancies and solid tumors. Though the spectrum of clinical activity and duration of response seen with these agents is promising, objective response is limited to a subset of patients and is often associated with distinct side effects that are potentially life-threatening. With increasing use of checkpoint inhibitors as standard of care and in clinical trials, the burden of immune-related adverse events will undoubtedly increase. Given these limitations and increase in health care costs associated with such therapies, it is essential to identify patients who are likely to respond to immunotherapy and those who are at a risk for developing treatment-related side effects. This new edition will inform readers on the latest in biomarker development to identify patients who are more likely to respond, and strategies to overcome the challenges of immune-related adverse events. In addition, the authors recognize that including the missing patient voice in clinical trials and longitudinal assessment of symptom reports may help to identify early indicators of response or toxicity. Thus, the book includes a chapter on patient-reported outcomes in patients treated with immunotherapies. The authors believe that acquiring this knowledge will help health care professionals make informed treatment decisions.Edited by two renowned experts in the field, the book’s chapters are written by a diverse cast of experts conducting cutting-edge research, providing the reader with the most up-to-date science.
Автор: Hironori Nakagami Название: Therapeutic Vaccines as Novel Immunotherapy ISBN: 9813296305 ISBN-13(EAN): 9789813296305 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Поставка под заказ. Описание: This book offers an excellent introduction to the use of novel therapeutic vaccines for common diseases based on their ability to induce antibody production.
Автор: Naing Aung, Hajjar Joud Название: Immunotherapy ISBN: 3030793079 ISBN-13(EAN): 9783030793074 Издательство: Springer Рейтинг: Цена: 204970.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: As more immunotherapeutic agents are used in the clinic, it is important to provide updates about current and ongoing developments in the field to further research efforts and inform treatment decisions. The fourth edition will have a new focus on strategies to overcome the challenges associated with immunotherapy.
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