Cell Reprogramming for Immunotherapy, Samuel G. Katz; Peter M. Rabinovich
Автор: Rong-Fu Wang Название: Innate Immune Regulation and Cancer Immunotherapy ISBN: 1489985905 ISBN-13(EAN): 9781489985903 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Innate and adaptive immunity play important roles in immunosurveillance and tumor destruction. This book discusses recent progress in innate immunity and Treg cells, and the regulation of innate immunity through Toll-like receptor (TLR) signalling.
Автор: Marc S. Ernstoff, Igor Puzanov, Caroline Robert, Adi M. Diab, Peter M. Hersey Название: SITC`s Guide to Immunotherapy Toxicity: Best Practices for Managing Side Effects of Cancer Treatment ISBN: 0826172148 ISBN-13(EAN): 9780826172143 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 45270.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A practical reference to managing side effects associated with FDA-approved cancer immunotherapy drugs. Part One contains chapter-based overviews of immune checkpoint inhibitors in the clinic. Part Two is structured by common and uncommon toxicities that affect major organ sites throughout the body.
Автор: Kaplan Название: Immunotherapy in Transplantation: Principles and Practice ISBN: 1405182717 ISBN-13(EAN): 9781405182713 Издательство: Wiley Рейтинг: Цена: 211150.00 T Наличие на складе: Поставка под заказ. Описание: This comprehensive reference source will benefit all transplant specialists working with pharmacologic and biologic agents that modulate the immune system.
Название: Allergens and Allergen Immunotherapy ISBN: 0815382219 ISBN-13(EAN): 9780815382218 Издательство: Taylor&Francis Рейтинг: Цена: 183750.00 T Наличие на складе: Невозможна поставка. Описание: The Sixth edition of Lockey and Ledford`s Allergens and Allergen Immunotherapy continues to provide comprehensive coverage of all types of allergens and allergen vaccines, providing clinicians the essential information they need to accurately diagnose and manage all allergic conditions.
Автор: R.J.A. van Moorselaar; Frans M.J. Debruyne; Ronald Название: Immunotherapy of Renal Cell Carcinoma ISBN: 3540528350 ISBN-13(EAN): 9783540528357 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: With contributions by numerous experts
Автор: Donnadieu Название: Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy ISBN: 3319422219 ISBN-13(EAN): 9783319422213 Издательство: Springer Рейтинг: Цена: 139310.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.
The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.
Автор: Howard L. Kaufman; Jedd D. Wolchok Название: General Principles of Tumor Immunotherapy ISBN: 9400787146 ISBN-13(EAN): 9789400787148 Издательство: Springer Рейтинг: Цена: 156720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book brings together the world`s leading authorities on tumor immunology. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated.
Автор: Dranoff Название: Cancer Immunology and Immunotherapy ISBN: 3642141358 ISBN-13(EAN): 9783642141355 Издательство: Springer Рейтинг: Цена: 191560.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.
Developing Costimulatory Molecules for Immunotherapy of Diseases highlights the novel concept of reverse costimulation and how it can be effectively exploited to develop immunotherapy using either humanized antibodies against CD80, CD86, and other costimulatory molecules or CD28 fusinogenic proteins in the treatment of diseases, including allergies, asthma, rheumatoid arthritis, multiple sclerosis, lupus nephritis, severe psoriasis, vulgaris tuberculosis, thopoid, transplantation therapeutic, cancer, and inflammation.
The text aims to provide the latest information on the complex roles and interactions within the CD28 and B7 costimulatory families, with the hope that targeting these families will yield new therapies for the treatment of inflammation, autoimmunity, transplantation, cancer, and other infectious diseases.
Автор: William E. Schiesser Название: Spatiotemporal Modeling of Cancer Immunotherapy ISBN: 3030176355 ISBN-13(EAN): 9783030176358 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The focus of this book is a detailed discussion of a dual cancer vaccine (CV)-immune checkpoint inhibitor (ICI) mathematical model formulated as a system of partial differential equations (PDEs) defining the spatiotemporal distribution of cells and biochemicals during tumor growth.A computer implementation of the model is discussed in detail for the quantitative evaluation of CV-ICI therapy. The coding (programming) consists of a series of routines in R, a quality, open-source scientific computing system that is readily available from the internet. The routines are based on the method of lines (MOL), a general PDE algorithm that can be executed on modest computers within the basic R system. The reader can download and use the routines to confirm the model solutions reported in the book, then experiment with the model by varying the parameters and modifying/extending the equations, and even studying alternative models with the PDE methodology demonstrated by the CV-ICI model.Spatiotemporal Modeling of Cancer Immunotherapy: Partial Differential Equation Analysis in R facilitates the use of the model, and more generally, computer- based analysis of cancer immunotherapy mathematical models, as a step toward the development and quantitative evaluation of the immunotherapy approach to the treatment of cancer.To download the R routines, please visit: http://www.lehigh.edu/~wes1/ci_download
Автор: Lockey / Ledford Название: Allergens and Allergen Immunotherapy, Fourth Edition ISBN: 1420061976 ISBN-13(EAN): 9781420061970 Издательство: Informa Рейтинг: Цена: 139800.00 T Наличие на складе: Нет в наличии. Описание: Compiling the research of an influential team of investigators and scientists, Allergens and Allergen Immunotherapy is filled with quick reference charts, tables and indexes. Allergists, immunologists, and otolaryngologists will find this new streamlined fourth edition a great practical reference for on-the-go diagnosis, treatment, and management of allergies.
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