Aptamers, Gulab Singh Yadav; Vikas Kumar; Neeraj K. Aggarwal

Автор: Weihong Tan; Xiaohong Fang
Название: Aptamers Selected by Cell-SELEX for Theranostics
ISBN: 3662462257 ISBN-13(EAN): 9783662462256
Издательство: Springer
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Цена: 121110.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This edited volume describes cell-SELEX as the fundamental tool used to generate aptamer molecules for a wide range of applications in molecular medicine, bioanalysis and chemical biology. Easily integrated into the natural heterogeneous cell matrix, aptamers can be effectively used in theranostics, bioanalysis, environment detection and biomedical studies. The book gathers reviews that reflect the latest advances in the field of aptamers and consists in fourteen chapters demonstrating essential examples of these aptamers and aptamer-nanomaterial assemblies, depending on the types of applications and biological systems. It also includes a separate chapter on the utilization of aptamers in real clinics and what will be required to achieve this significant goal. The book will be both appealing and useful to a broad audience, including biologists, bioscientists, and clinicians whose interests range from chemistry and biomedical engineering to cell and molecular biology and biotechnology. Weihong Tan is a Distinguished Professor of Chemistry and Biomedical Engineering at Hunan University, China and also a University of Florida Distinguished Professor and V.T. and Louis Jackson Professor of Chemistry at the University of Florida, USA. Xiaohong Fang is a Professor at the Institute of Chemistry, Chinese Academy of Sciences, China.

Автор: G?nter Mayer
Название: Nucleic Acid Aptamers
ISBN: 1493931962 ISBN-13(EAN): 9781493931965
Издательство: Springer
Рейтинг:
Цена: 130430.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

Part I: Selection

1. Selection of Aptamers for Metabolite Sensing and Construction of Optical Nanosensors

Yi Long, Franziska Pfeiffer, Gьnter Mayer, Tine Daa Schr der, Veli Cengiz Цzalp, and Lars Folke Olsen

2. SELEX of Cell-Specific RNA Aptamers

Katharina Berg, Eileen Magbanua, and Ulrich Hahn

3. Developing Aptamers by Cell-Based SELEX

Silvia Catuogno, Carla Lucia Esposito, and Vittorio de Franciscis

4. DNA Aptamer Generation by Genetic Alphabet Expansion SELEX (ExSELEX) Using an Unnatural Base Pair System

Michiko Kimoto, Ken-Ichiro Matsunaga, and Ichiro Hirao

5. Capillary Electrophoresis for the Selection of DNA Aptamers Recognizing Activated Protein C

Nasim Shahidi Hamedani and Jens Mьller

6. Preparation of SELEX Samples for Next-Generation Sequencing

Fabian Tolle and Gьnter Mayer

7. Next Generation Analysis of Deep Sequencing Data: Bringing Light into the Black Box of SELEX Experiments

Michael Blank

Part II: Characterization

8. Aptamer Binding Studies Using MicroScale Thermophoresis

Dennis Breitsprecher, Nina Schlinck, David Witte, Stefan Duhr, Philipp Baaske, and Thomas Schubert

9. Label-Free Determination of the Dissociation Constant of Small Molecule-Aptamer Interaction by Isothermal Titration Calorimetry

Marc Vogel and Beatrix Suess

10. Applications of Aptamers in Flow and Imaging Cytometry

Isis C. Nascimento, Arthur A. Nery, Vinicius Bassaneze, Josй E. Krieger, and Henning Ulrich

11. In Vitro and In Vivo Imaging of Fluorescent Aptamers

Ioanna Thйodorou, Nam Nguyen Quang, Karine Gombert, Benoit Thйzй, Benoit Lelandais, and Frйdйric Ducongй

12. Crystallographic Pursuit of a Protein-RNA Aptamer Complex

John J.G. Tesmer

Part III: Application

13. Voltammetric Aptasensor Based on Magnetic Beads Assay for Detection of Human Activated Protein C

Arzum Erdem, Gulsah Congur, and Ece Eksin

14. Apta-PCR

Alessandro Pinto, Pedro Nadal Polo, Marketa Svobodova, Teresa Mairal Lerga, and Ciara K. O'Sullivan

15. Aptamer-Based Enzyme-Capture-Assay for Measurement of Plasma Thrombin Levels

Jens Mьller, Tobias Becher, Gьnter Mayer, and Bernd Pцtzsch

16. Application of Aptamers in Histopathology

Sarah Shigdar, Li Lv, Lifen Wang, and Wei Duan

17. Aptamer Stainings for Super-Resolution Microscopy

Maria Angela Gomes de Castro, Burkhard Rammner, and Felipe Opazo

18. Synthesis and Characterization of Aptamer Targeted SNALPs for the Delivery of siRNA

Samantha E. Wilner and Matthew Levy

19. Screening of Genetic Switches Based on the Twister Ribozyme Motif

Michele Felletti, Benedikt Klauser, and Jцrg S. Hartig

Автор: Man Bock Gu
Название: Biosensors Based on Aptamers and Enzymes
ISBN: 3662522454 ISBN-13(EAN): 9783662522455
Издательство: Springer
Рейтинг:
Цена: 260870.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.

Автор: Gulab Singh Yadav; Vikas Kumar; Neeraj K. Aggarwal
Название: Aptamers
ISBN: 9811388350 ISBN-13(EAN): 9789811388354
Издательство: Springer
Рейтинг:
Цена: 121110.00 T
Наличие на складе: Поставка под заказ.
Описание:

Автор: Mayer Gunter
Название: Nucleic Acid Aptamers: Selection, Characterization, and Application
ISBN: 1493949349 ISBN-13(EAN): 9781493949342
Издательство: Springer
Рейтинг:
Цена: 93160.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

Part I: Selection

1. Selection of Aptamers for Metabolite Sensing and Construction of Optical Nanosensors

Yi Long, Franziska Pfeiffer, Gьnter Mayer, Tine Daa Schr der, Veli Cengiz Цzalp, and Lars Folke Olsen

2. SELEX of Cell-Specific RNA Aptamers

Katharina Berg, Eileen Magbanua, and Ulrich Hahn

3. Developing Aptamers by Cell-Based SELEX

Silvia Catuogno, Carla Lucia Esposito, and Vittorio de Franciscis

4. DNA Aptamer Generation by Genetic Alphabet Expansion SELEX (ExSELEX) Using an Unnatural Base Pair System

Michiko Kimoto, Ken-Ichiro Matsunaga, and Ichiro Hirao

5. Capillary Electrophoresis for the Selection of DNA Aptamers Recognizing Activated Protein C

Nasim Shahidi Hamedani and Jens Mьller

6. Preparation of SELEX Samples for Next-Generation Sequencing

Fabian Tolle and Gьnter Mayer

7. Next Generation Analysis of Deep Sequencing Data: Bringing Light into the Black Box of SELEX Experiments

Michael Blank

Part II: Characterization

8. Aptamer Binding Studies Using MicroScale Thermophoresis

Dennis Breitsprecher, Nina Schlinck, David Witte, Stefan Duhr, Philipp Baaske, and Thomas Schubert

9. Label-Free Determination of the Dissociation Constant of Small Molecule-Aptamer Interaction by Isothermal Titration Calorimetry

Marc Vogel and Beatrix Suess

10. Applications of Aptamers in Flow and Imaging Cytometry

Isis C. Nascimento, Arthur A. Nery, Vinicius Bassaneze, Josй E. Krieger, and Henning Ulrich

11. In Vitro and In Vivo Imaging of Fluorescent Aptamers

Ioanna Thйodorou, Nam Nguyen Quang, Karine Gombert, Benoit Thйzй, Benoit Lelandais, and Frйdйric Ducongй

12. Crystallographic Pursuit of a Protein-RNA Aptamer Complex

John J.G. Tesmer

Part III: Application

13. Voltammetric Aptasensor Based on Magnetic Beads Assay for Detection of Human Activated Protein C

Arzum Erdem, Gulsah Congur, and Ece Eksin

14. Apta-PCR

Alessandro Pinto, Pedro Nadal Polo, Marketa Svobodova, Teresa Mairal Lerga, and Ciara K. O'Sullivan

15. Aptamer-Based Enzyme-Capture-Assay for Measurement of Plasma Thrombin Levels

Jens Mьller, Tobias Becher, Gьnter Mayer, and Bernd Pцtzsch

16. Application of Aptamers in Histopathology

Sarah Shigdar, Li Lv, Lifen Wang, and Wei Duan

17. Aptamer Stainings for Super-Resolution Microscopy

Maria Angela Gomes de Castro, Burkhard Rammner, and Felipe Opazo

18. Synthesis and Characterization of Aptamer Targeted SNALPs for the Delivery of siRNA

Samantha E. Wilner and Matthew Levy

19. Screening of Genetic Switches Based on the Twister Ribozyme Motif

Michele Felletti, Benedikt Klauser, and Jцrg S. Hartig

Автор: Man Bock Gu; Hak-Sung Kim
Название: Biosensors Based on Aptamers and Enzymes
ISBN: 3642541429 ISBN-13(EAN): 9783642541421
Издательство: Springer
Рейтинг:
Цена: 260870.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification.

Автор: Urmann Katharina, Walter Johanna-Gabriela
Название: Aptamers in Biotechnology
ISBN: 303054060X ISBN-13(EAN): 9783030540609
Издательство: Springer
Рейтинг:
Цена: 354040.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book reviews the development, characterization and applications of aptamers in different areas of biotechnology ranging from therapeutics to diagnostics and protein purification. Hailed as chemical antibodies, these single-stranded nucleic acid receptors were predicted to supersede antibodies in traditional assays, such as ELISA, within a short time. While this has yet to happen, readers will find in this book a deep insight into the progress of aptamer technology and a critical discussion about the limitations that need to be overcome in order to find wider acceptance and use outside of the still relatively small aptamer-community. This book covers all aspects of aptamer generation and application for the aptamer-experienced reader and curious novice alike, with the addition of an industry perspective on the future of aptamer-use in biotechnology.