Aptamers in Biotechnology, Urmann Katharina, Walter Johanna-Gabriela
Автор: Molly Fitzgerald-Hayes Название: DNA and Biotechnology, ISBN: 0120489309 ISBN-13(EAN): 9780120489305 Издательство: Elsevier Science Рейтинг: Цена: 79730.00 T Наличие на складе: Поставка под заказ. Описание: Suitable for a wide range of disciplines, from biology to non-biology, law and nursing majors, this title offers the educated layperson a survey of DNA by presenting a brief history of genetics, an outline of techniques that are in use, and highlights of breakthroughs in scientific discoveries.
Автор: Lundblad Название: Biotechnology of Plasma Proteins ISBN: 1439850267 ISBN-13(EAN): 9781439850268 Издательство: Taylor&Francis Рейтинг: Цена: 193950.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
The fractionation of human blood plasma can be considered to be a mature industry, with the basic technology, alcohol fractionation, dating back at least to the 1940s. Many of the products described in the current work have been approved biologics since the 1950s. The information gathered from the development of plasma proteins has proved vital to the development of recombinant therapeutic proteins.
Discussing the role of plasma proteins in current biotechnology, Biotechnology of Plasma Proteins describes the protein composition of human plasma, the fractionation of plasma to obtain therapeutic proteins, and the analysis of these products. It delineates the path from plasma products to recombinant products, and highlights products from albumin, intravenous immunoglobins, and coagulation. It offers a comprehensive review of current techniques for the analysis of proteins including electrophoresis, chromatography, spectrophotometry, mass spectrometry, and updates not published since 1975.
Key Topics
Protein Composition of Plasma
Proteomic methods for plasma protein analysis
Plasma protein biomarkers
Validation of biomarkers
Assays for plasma biomarkers
Methods for the Analysis of Protein Products
Assay development and validation
Electrophoresis
Chromatography
Immunoassay
Mass spectrometry
Raman spectroscopy
Plasma Fractionation: Historical and Modern Methods
An Introduction to Ethical, Safety and Intellectual Property Rights Issues in Biotechnology provides a comprehensive look at the biggest technologies that have revolutionized biology since the early 20th century, also discussing their impact on society.
The book focuses on issues related to bioethics, biosafety and intellectual property rights, and is written in an easy-to-understand manner for graduate students and early career researchers interested in the opportunities and challenges associated with advances in biotechnology.
Important topics covered include the Human Genome Project, human cloning, rDNA technology, the 3Rs and animal welfare, bioterrorism, human rights and genetic discrimination, good laboratory practices, good manufacturing practices, the protection of biological material and much more.
Full of relevant case studies, practical examples, weblinks and resources for further reading, this book offers an essential and holistic look at the ways in which biotechnology has affected our global society.
Автор: Man Bock Gu; Hak-Sung Kim Название: Biosensors Based on Aptamers and Enzymes ISBN: 3642541429 ISBN-13(EAN): 9783642541421 Издательство: Springer Рейтинг: Цена: 260870.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification.
Автор: Gulab Singh Yadav; Vikas Kumar; Neeraj K. Aggarwal Название: Aptamers ISBN: 9811388385 ISBN-13(EAN): 9789811388385 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Поставка под заказ. Описание: The book discusses the basics of aptamers and the advent of aptamer-based technology in recent times.
Автор: G?nter Mayer Название: Nucleic Acid Aptamers ISBN: 1493931962 ISBN-13(EAN): 9781493931965 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Part I: Selection
1. Selection of Aptamers for Metabolite Sensing and Construction of Optical Nanosensors
Yi Long, Franziska Pfeiffer, Gьnter Mayer, Tine Daa Schr der, Veli Cengiz Цzalp, and Lars Folke Olsen
2. SELEX of Cell-Specific RNA Aptamers
Katharina Berg, Eileen Magbanua, and Ulrich Hahn
3. Developing Aptamers by Cell-Based SELEX
Silvia Catuogno, Carla Lucia Esposito, and Vittorio de Franciscis
4. DNA Aptamer Generation by Genetic Alphabet Expansion SELEX (ExSELEX) Using an Unnatural Base Pair System
Michiko Kimoto, Ken-Ichiro Matsunaga, and Ichiro Hirao
5. Capillary Electrophoresis for the Selection of DNA Aptamers Recognizing Activated Protein C
Nasim Shahidi Hamedani and Jens Mьller
6. Preparation of SELEX Samples for Next-Generation Sequencing
Fabian Tolle and Gьnter Mayer
7. Next Generation Analysis of Deep Sequencing Data: Bringing Light into the Black Box of SELEX Experiments
Michael Blank
Part II: Characterization
8. Aptamer Binding Studies Using MicroScale Thermophoresis
Dennis Breitsprecher, Nina Schlinck, David Witte, Stefan Duhr, Philipp Baaske, and Thomas Schubert
9. Label-Free Determination of the Dissociation Constant of Small Molecule-Aptamer Interaction by Isothermal Titration Calorimetry
Marc Vogel and Beatrix Suess
10. Applications of Aptamers in Flow and Imaging Cytometry
Isis C. Nascimento, Arthur A. Nery, Vinicius Bassaneze, Josй E. Krieger, and Henning Ulrich
11. In Vitro and In Vivo Imaging of Fluorescent Aptamers
Ioanna Thйodorou, Nam Nguyen Quang, Karine Gombert, Benoit Thйzй, Benoit Lelandais, and Frйdйric Ducongй
12. Crystallographic Pursuit of a Protein-RNA Aptamer Complex
John J.G. Tesmer
Part III: Application
13. Voltammetric Aptasensor Based on Magnetic Beads Assay for Detection of Human Activated Protein C
Arzum Erdem, Gulsah Congur, and Ece Eksin
14. Apta-PCR
Alessandro Pinto, Pedro Nadal Polo, Marketa Svobodova, Teresa Mairal Lerga, and Ciara K. O'Sullivan
15. Aptamer-Based Enzyme-Capture-Assay for Measurement of Plasma Thrombin Levels
Jens Mьller, Tobias Becher, Gьnter Mayer, and Bernd Pцtzsch
16. Application of Aptamers in Histopathology
Sarah Shigdar, Li Lv, Lifen Wang, and Wei Duan
17. Aptamer Stainings for Super-Resolution Microscopy
Maria Angela Gomes de Castro, Burkhard Rammner, and Felipe Opazo
18. Synthesis and Characterization of Aptamer Targeted SNALPs for the Delivery of siRNA
Samantha E. Wilner and Matthew Levy
19. Screening of Genetic Switches Based on the Twister Ribozyme Motif
Michele Felletti, Benedikt Klauser, and Jцrg S. Hartig
Автор: Ajar Nath Yadav, Shashank Mishra Название: Recent advancement in white biotechnology through fungi : ISBN: 3030104796 ISBN-13(EAN): 9783030104795 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: White biotechnology, or industrial biotechnology as it is also known, refers to the use of living cells and/or their enzymes to create industrial products that are more easily degradable, require less energy, create less waste during production and sometimes perform better than products created using traditional chemical processes.
Название: Medical applications of artificial intelligence ISBN: 1138072273 ISBN-13(EAN): 9781138072275 Издательство: Taylor&Francis Рейтинг: Цена: 78590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Enhanced, more reliable, and better understood than in the past, artificial intelligence (AI) systems can make providing healthcare more accurate, affordable, accessible, consistent, and efficient. However, AI technologies have not been as well integrated into medicine as predicted. In order to succeed, medical and computational scientists must develop hybrid systems that can effectively and efficiently integrate the experience of medical care professionals with capabilities of AI systems.
After providing a general overview of artificial intelligence concepts, tools, and techniques, Medical Applications of Artificial Intelligence reviews the research, focusing on state-of-the-art projects in the field. The book captures the breadth and depth of the medical applications of artificial intelligence, exploring new developments and persistent challenges.
Автор: Weihong Tan; Xiaohong Fang Название: Aptamers Selected by Cell-SELEX for Theranostics ISBN: 3662462257 ISBN-13(EAN): 9783662462256 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This edited volume describes cell-SELEX as the fundamental tool used to generate aptamer molecules for a wide range of applications in molecular medicine, bioanalysis and chemical biology. Easily integrated into the natural heterogeneous cell matrix, aptamers can be effectively used in theranostics, bioanalysis, environment detection and biomedical studies. The book gathers reviews that reflect the latest advances in the field of aptamers and consists in fourteen chapters demonstrating essential examples of these aptamers and aptamer-nanomaterial assemblies, depending on the types of applications and biological systems. It also includes a separate chapter on the utilization of aptamers in real clinics and what will be required to achieve this significant goal. The book will be both appealing and useful to a broad audience, including biologists, bioscientists, and clinicians whose interests range from chemistry and biomedical engineering to cell and molecular biology and biotechnology. Weihong Tan is a Distinguished Professor of Chemistry and Biomedical Engineering at Hunan University, China and also a University of Florida Distinguished Professor and V.T. and Louis Jackson Professor of Chemistry at the University of Florida, USA. Xiaohong Fang is a Professor at the Institute of Chemistry, Chinese Academy of Sciences, China.
1. Selection of Aptamers for Metabolite Sensing and Construction of Optical Nanosensors
Yi Long, Franziska Pfeiffer, Gьnter Mayer, Tine Daa Schr der, Veli Cengiz Цzalp, and Lars Folke Olsen
2. SELEX of Cell-Specific RNA Aptamers
Katharina Berg, Eileen Magbanua, and Ulrich Hahn
3. Developing Aptamers by Cell-Based SELEX
Silvia Catuogno, Carla Lucia Esposito, and Vittorio de Franciscis
4. DNA Aptamer Generation by Genetic Alphabet Expansion SELEX (ExSELEX) Using an Unnatural Base Pair System
Michiko Kimoto, Ken-Ichiro Matsunaga, and Ichiro Hirao
5. Capillary Electrophoresis for the Selection of DNA Aptamers Recognizing Activated Protein C
Nasim Shahidi Hamedani and Jens Mьller
6. Preparation of SELEX Samples for Next-Generation Sequencing
Fabian Tolle and Gьnter Mayer
7. Next Generation Analysis of Deep Sequencing Data: Bringing Light into the Black Box of SELEX Experiments
Michael Blank
Part II: Characterization
8. Aptamer Binding Studies Using MicroScale Thermophoresis
Dennis Breitsprecher, Nina Schlinck, David Witte, Stefan Duhr, Philipp Baaske, and Thomas Schubert
9. Label-Free Determination of the Dissociation Constant of Small Molecule-Aptamer Interaction by Isothermal Titration Calorimetry
Marc Vogel and Beatrix Suess
10. Applications of Aptamers in Flow and Imaging Cytometry
Isis C. Nascimento, Arthur A. Nery, Vinicius Bassaneze, Josй E. Krieger, and Henning Ulrich
11. In Vitro and In Vivo Imaging of Fluorescent Aptamers
Ioanna Thйodorou, Nam Nguyen Quang, Karine Gombert, Benoit Thйzй, Benoit Lelandais, and Frйdйric Ducongй
12. Crystallographic Pursuit of a Protein-RNA Aptamer Complex
John J.G. Tesmer
Part III: Application
13. Voltammetric Aptasensor Based on Magnetic Beads Assay for Detection of Human Activated Protein C
Arzum Erdem, Gulsah Congur, and Ece Eksin
14. Apta-PCR
Alessandro Pinto, Pedro Nadal Polo, Marketa Svobodova, Teresa Mairal Lerga, and Ciara K. O'Sullivan
15. Aptamer-Based Enzyme-Capture-Assay for Measurement of Plasma Thrombin Levels
Jens Mьller, Tobias Becher, Gьnter Mayer, and Bernd Pцtzsch
16. Application of Aptamers in Histopathology
Sarah Shigdar, Li Lv, Lifen Wang, and Wei Duan
17. Aptamer Stainings for Super-Resolution Microscopy
Maria Angela Gomes de Castro, Burkhard Rammner, and Felipe Opazo
18. Synthesis and Characterization of Aptamer Targeted SNALPs for the Delivery of siRNA
Samantha E. Wilner and Matthew Levy
19. Screening of Genetic Switches Based on the Twister Ribozyme Motif
Michele Felletti, Benedikt Klauser, and Jцrg S. Hartig
Автор: Man Bock Gu Название: Biosensors Based on Aptamers and Enzymes ISBN: 3662522454 ISBN-13(EAN): 9783662522455 Издательство: Springer Рейтинг: Цена: 260870.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.
Автор: Freshney R Ian Название: Culture of Animal Cells - A Manual of Basic Technique and Sp ISBN: 1118873653 ISBN-13(EAN): 9781118873656 Издательство: Wiley Рейтинг: Цена: 83370.00 T Наличие на складе: Поставка под заказ. Описание: Since the publication of the sixth edition of this benchmark text, numerous advances in the field have been made particularly in stem cells, 3D culture, scale-up, STR profiling, and culture of specialized cells. Culture of Animal Cells: A Manual of
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