Автор: Rahman, Shafiqur Название: The Brain As A Drug Target,98 ISBN: 0123855063 ISBN-13(EAN): 9780123855060 Издательство: Elsevier Science Рейтинг: Цена: 140360.00 T Наличие на складе: Поставка под заказ. Описание: The brain is protected by the blood-brain barrier and this barrier prevents many drugs from entering the brain. This title discusses various drug delivery and targeting strategies that are being developed to enhance the transport and distribution of drugs into the brain. It discusses discoveries, approaches, and ideas.
Автор: Mark von Itzstein Название: Influenza Virus Sialidase - A Drug Discovery Target ISBN: 3034807791 ISBN-13(EAN): 9783034807791 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Following an overview of the influenza virus, the haemagglutinin, the interactions with the cell receptors and the enzymology of virus sialidase, recent results in drug design are presented.
Автор: Jurgen Moll; Riccardo Colombo Название: Target Identification and Validation in Drug Discovery ISBN: 1493962787 ISBN-13(EAN): 9781493962785 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The major reason for the elevated costs of drug development in the pharmaceutical industry is the high attrition rate. In Target Identification and Validation in Drug Discovery: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to identify and validate new target. These include methods and approaches covering biochemical, cell based, in vivo models and translational methods. Chapters also include selected case reports that demonstrate the integration of these technologies to real life experiences and to demonstrate the multiple use of more than one technology to increase knowledge on a specific target. These Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Target Identification and Validation in Drug Discovery: Methods and Protocols contains a comprehensive list of essential methods and clear protocols to follow.
Автор: Jurgen Moll; Riccardo Colombo Название: Target Identification and Validation in Drug Discovery ISBN: 1627033106 ISBN-13(EAN): 9781627033107 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This Methods in Molecular Biology (TM) book details current procedures for identifying and validating new drug targets. Includes methods and approaches covering biochemical, cell based, in vivo models and translational methods, as well as relevant case reports.
Название: Multi-target drug design using chem-bioinformatic approaches ISBN: 1493987321 ISBN-13(EAN): 9781493987320 Издательство: Springer Рейтинг: Цена: 204970.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This detailed book showcases recent advances in computational design of multi-target drug candidates involving various ligand and structure-based strategies.
Автор: Scotti Название: Drug Target Selection and Validation ISBN: 3030958949 ISBN-13(EAN): 9783030958947 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The first book in the newly created book series, Computer-Aided Drug Discovery and Design, focuses on the computational aspects of early drug discovery, drug target identification, and validation.
Автор: J?rgen Moll; Sebastian Carotta Название: Target Identification and Validation in Drug Discovery ISBN: 1493991442 ISBN-13(EAN): 9781493991440 Издательство: Springer Рейтинг: Цена: 158380.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This second edition book explores breakthrough technologies in the field of drug target identification and validation. The volume emphasizes particularly revolutionary technologies, such as CRISPR-related screening, “big data,” and in silico approaches, as well as in vivo applications of CRISPR and best uses of animal models in drug development. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Fully updated and authoritative, Target Identification and Validation in Drug Discovery: Methods and Protocols, Second Edition is an ideal guide for molecular and cellular biologists, pharmacologists, pathologists, bioinformaticians, clinical researchers, or investigators, as well as experts in other fields that need a quick overview of these state-of-the-art technologies.
