Автор: Ilmoniemi Risto, Sarvas Jukka Название: Brain Signals: Physics and Mathematics of Meg and Eeg ISBN: 0262039826 ISBN-13(EAN): 9780262039826 Издательство: MIT Press Рейтинг: Цена: 73360.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A unified treatment of the generation and analysis of brain-generated electromagnetic fields.
Автор: H?l?ne Girouard Название: Hypertension and the Brain as an End-Organ Target ISBN: 3319256149 ISBN-13(EAN): 9783319256146 Издательство: Springer Рейтинг: Цена: 130610.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The first comprehensive overview of the effects of hypertension on the brain. The book discusses not only the relationship between hypertension and stroke, but also the much less studied relationship between hypertension and cognitive decline and neurodegenerative diseases such as Alzheimer`s.
Автор: Mark von Itzstein Название: Influenza Virus Sialidase - A Drug Discovery Target ISBN: 3034807791 ISBN-13(EAN): 9783034807791 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Following an overview of the influenza virus, the haemagglutinin, the interactions with the cell receptors and the enzymology of virus sialidase, recent results in drug design are presented.
Автор: Li Di,Edward H. Kerns Название: Blood-Brain Barrier in Drug Discovery: Optimizing Brain Exposure of CNS Drugs and Minimizing Brain Side Effects for Peripheral Drugs ISBN: 1118788354 ISBN-13(EAN): 9781118788356 Издательство: Wiley Рейтинг: Цена: 136170.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant and most challenging areas of drug discovery.
Автор: David Kobiler; Shlomo Lustig; Shlomo Shapira Название: Blood-Brain Barrier ISBN: 1461351413 ISBN-13(EAN): 9781461351412 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of the 44th OHOLO Conference on Blood-Brain Barrier: Drug Delivery and Brain Pathology, held September 10-14, 2000, Dead Sea, Israel
Автор: Marco F. Schmidt Название: Drug Target miRNA ISBN: 1493982362 ISBN-13(EAN): 9781493982363 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Поставка под заказ. Описание: "Published In: United States, 07 December 2016"--Distributor`s website.
Автор: Jurgen Moll; Riccardo Colombo Название: Target Identification and Validation in Drug Discovery ISBN: 1493962787 ISBN-13(EAN): 9781493962785 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The major reason for the elevated costs of drug development in the pharmaceutical industry is the high attrition rate. In Target Identification and Validation in Drug Discovery: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to identify and validate new target. These include methods and approaches covering biochemical, cell based, in vivo models and translational methods. Chapters also include selected case reports that demonstrate the integration of these technologies to real life experiences and to demonstrate the multiple use of more than one technology to increase knowledge on a specific target. These Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Target Identification and Validation in Drug Discovery: Methods and Protocols contains a comprehensive list of essential methods and clear protocols to follow.
Автор: J?rgen Moll; Sebastian Carotta Название: Target Identification and Validation in Drug Discovery ISBN: 1493991442 ISBN-13(EAN): 9781493991440 Издательство: Springer Рейтинг: Цена: 158380.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This second edition book explores breakthrough technologies in the field of drug target identification and validation. The volume emphasizes particularly revolutionary technologies, such as CRISPR-related screening, “big data,” and in silico approaches, as well as in vivo applications of CRISPR and best uses of animal models in drug development. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Fully updated and authoritative, Target Identification and Validation in Drug Discovery: Methods and Protocols, Second Edition is an ideal guide for molecular and cellular biologists, pharmacologists, pathologists, bioinformaticians, clinical researchers, or investigators, as well as experts in other fields that need a quick overview of these state-of-the-art technologies.
Название: Nanoparticles for brain drug delivery ISBN: 981487731X ISBN-13(EAN): 9789814877312 Издательство: Taylor&Francis Рейтинг: Цена: 141890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book gathers contributions from experts in different, complementary fields, having in common their interest in developing new strategies for brain delivery based on nanotechnologies. It encompasses general aspects pertaining to fundamental development, as well as a diversity of nanomedicines applied in treatment and/or diagnosis.
Автор: Lennart Domell?f Название: Drug Delivery in Cancer Treatment III ISBN: 3642759408 ISBN-13(EAN): 9783642759406 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The European School of Oncology came into existence to respond to a need for informa- tion, education and training in the field of the diagnosis and treatment of cancer. There are two main reasons why such an initiative was considered necessary. Firstly, the teaching of oncology requires a rigorously multidisciplinary approach wh ich is difficult for the Univer- sities to put into practice since their system is mainly disciplinary orientated. Secondly, the rate of technological development that impinges on the diagnosis and treatment of cancer has been so rapid that it is not an easy task for medical faculties to adapt their curricula flexibly. With its residential courses for organ pathologies and the seminars on new techniques (laser, monocional antibodies, imaging techniques etc.) or on the principal therapeutic controversies (conservative or mutilating surgery, primary or adjuvant chemotherapy, radiotherapy alone or integrated), it is the ambition of the European School of Oncology to fill a cultural and scientific gap and, thereby, create a bridge between the University and Industry and between these two and daily medical practice. One of the more recent initiatives of ESO has been the institution of permanent study groups, also called task forces, where a limited number of leading experts are invited to meet once a year with the aim of defining the state of the art and possibly reaching a consensus on future developments in specific fields of oncology.
Автор: Morales Javier O., Gaillard Pieter J. Название: Nanomedicines for Brain Drug Delivery ISBN: 1071608371 ISBN-13(EAN): 9781071608371 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume explores the latest research in central nervous system (CNS) targeted nanocarriers, methods for their synthesis, and its characterization process. Chapters in this book cover topics such as polymeric nanoparticles and liposomes; self-assembled peptide-based scaffolds for lesions of the nervous system; use of peptides as CNS drugs and as potential carriers to optimize brain-targeted delivery; ways to model and assess blood brain barrier absorption of drugs; and the role of neurodegeneration progress of nanomaterials and their potential toxicity concerns. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Thorough and cutting-edge, Nanomedicines for Brain Drug Delivery is a valuable resource that will help researchers guide and advance the field of nanomedicines for the brain and nervous system.
Автор: Girouard Hйlиne Название: Hypertension and the Brain as an End-Organ Target ISBN: 3319798154 ISBN-13(EAN): 9783319798158 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The first comprehensive overview of the effects of hypertension on the brain. The book discusses not only the relationship between hypertension and stroke, but also the much less studied relationship between hypertension and cognitive decline and neurodegenerative diseases such as Alzheimer's. It seeks to answer two important questions. First, what are the conditions under which hypertension is associated with stroke, cognitive decline, and neurodegenerative disease? And second, what are the biological mechanisms by which hypertension alters brain homeostasis? By looking at the biological mechanisms of these relationships, this book provides insight to neuroscientists and neurologists regarding why anti-hypertension treatments make a big difference in the case of stroke, but have very little impact on cognitive decline and brain aging.
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