Resistance to Targeted Therapies Against Adult Brain Cancers, Tivnan Amanda

Автор: Schulz
Название: Molecular Biology of Human Cancers
ISBN: 3031162854 ISBN-13(EAN): 9783031162855
Издательство: Springer
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Цена: 149060.00 T
Наличие на складе: Поставка под заказ.
Описание: This textbook describes the most relevant molecular and biological processes in cancer, how they contribute to the development and progression of individual cancer types in humans, and how insights from molecular cancer research can be applied to improve cancer prevention, diagnostics and treatment. Part I of the textbook summarizes the current fundamental knowledge on the general properties of cancers, the causes of cancer, cancer genetics, genomics and epigenetics. Individual chapters address the functions of DNA damage and repair, oncogenes and tumor suppressors in carcinogenesis and discuss crucial mechanisms in cancer pathogenesis, such as apoptosis and replicative senescence, as well as the most relevant signal transduction pathways and regulatory networks. Part I concludes with a chapter on tumor invasion and metastasis and tumor immunology. In Part II, the most relevant mechanisms acting in individual human cancers (and subtypes) are described in more detail. This central part of the book contains individual sections on the most common human cancers highlighting the diversity in their genetic, molecular and cellular pathogenic mechanisms. How insights from molecular cancer research are translated into improvements in prevention, diagnosis, and treatment is outlined in Part III. This new edition has been extensively revised and includes in particular updated information on cancer genomics, epigenetics, viral carcinogenesis, cancer diagnostics and cancer therapy and a new chapter on lung cancers. Now more than ever, cancer research is an interdisciplinary endeavor that requires a basic knowledge of commonly used terms, facts and concepts. The aim of this book is to provide advanced students and practitioners in various disciplines with this foundation, bridging the gap between standard textbooks of molecular biology, pathology and oncology on the one hand and the specialized cancer literature on the other.

Автор: Reed
Название: Rare and uncommon gynecological cancers
ISBN: 3642134912 ISBN-13(EAN): 9783642134913
Издательство: Springer
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Цена: 71730.00 T
Наличие на складе: Есть
Описание: This book is intended as a reference manual that will provide the busy clinician with up-to-date information on the diagnosis and treatment of uncommon and rare gynecological cancers. While standard textbooks briefly cover these tumors, this is intended as a more comprehensive yet easy-to-use guide. After opening chapters on epidemiology, pathology, and diagnostic imaging, the full range of infrequently encountered gynecological cancers (ovarian, uterine, cervical, vaginal, and vulval) is presented and discussed with the aid of high-quality illustrations. In each case, detailed attention is paid to both differential diagnosis and current treatment options. The book has been written by an international panel of experts and is the first to gather all the uncommon and rare gynecological cancers together within one volume.

Автор: G.P. Talwar
Название: Treatment of advanced stage cancers
ISBN: 8173199329 ISBN-13(EAN): 9788173199325
Издательство: Alpha Science
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Цена: 40000.00 T
Наличие на складе: Есть
Описание: Treatment of Advanced Stage Cancers describes newer options for treatment of advanced liver cancers; targeting of pancreatic cancers by silencing' RNA selective killing of tumour cells expressing hCG by a high affinity, high specificity antibody linked to curcumin.

Reviewed also are the next generation of recombinant immunotoxins; herbal formulations eliminating Human Papilloma Virus (HPV) in cervical cancer cells besides immune targeting of oncogenic proteins of HPV to achieve a therapeutic vaccine for carcinoma of cervix. The book discusses optimisation of antigens for anti-cancer vaccines and optimization of Dendritic cells and viral vectors for immunotherapy. Clinical and experimental results are reported on therapeutic benefits of cancers by Mycobacterium indicus pranii. (DCGI approved vaccine for leprosy marketed as Immuvac).

Other topics covered include treatment of Chronic Myeloid Leukemia, Radiation-Enhanced Immunotherapy of Advanced cancers, Neem leaf glycoproteins regulating immune response in cancer and biology of metastasis of Head and Neck cancers. A new blood test for early diagnosis of Epithelial Ovarian Cancers is also described. The opening chapter by the Nobel Laureate David Baltimore presents elegantly the role of Micro RNAs in chronic inflammatory response and cancers.

Автор: Jianguo Tao; Eduardo Sotomayor
Название: Hematologic Cancers: From Molecular Pathobiology to Targeted Therapeutics
ISBN: 9400795815 ISBN-13(EAN): 9789400795815
Издательство: Springer
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Цена: 156720.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book encompasses a decade of explosive growth in knowledge of the pathobiology of hematologic cancer, and offers the insight of experts from around the world on current treatment approaches and on future progress in malignant hematologic diseases.

Автор: Amanda Tivnan
Название: Resistance to Targeted Therapies Against Adult Brain Cancers
ISBN: 331946504X ISBN-13(EAN): 9783319465043
Издательство: Springer
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Цена: 156720.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume will bring together a review of research being carried out by international experts in this field, detailing treatment and research approaches in several forms of malignant brain tumors. These include glioblastoma (GBM), a highly aggressive and fatal form of astrocytoma which accounts for 80% of newly diagnosed brain tumor patients per year, and meningioma, of which 10% are malignant and extremely resistant to targeted therapies. The volume will also include a discussion of methods to overcome blood-brain barrier exclusion for more efficient targeted drug delivery in all forms of brain cancer treatment. The volume will include information on the repurposing of drugs in an attempt to circumvent drug resistance, use of small molecule inhibitors in GBM treatment, mechanisms of secondary brain metastasis, drug resistance, and state-of-the-art imaging of targeted therapies.

Автор: Ahmad, Sarfraz
Название: Overcoming Drug Resistance In Gynecologic Cancers,20
ISBN: 012824299X ISBN-13(EAN): 9780128242995
Издательство: Elsevier Science
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Цена: 153830.00 T
Наличие на складе: Поставка под заказ.
Описание: Digital Information Design (DID) is primarily a business information management (BIM) model. As with any model it is used to help you to describe problems and test potential solutions. DID is not like any other method or framework model; it is independent of any other existing model or framework and does not claim to manage the entirety of the design of business information services. DID identifies useful and widely used best practices that are designed specifically for use in any phase of business information service development from idea, conception, specification, design, test, handover, service management and operation, or managing architectural issues or hardware and software installation. Primarily, DID was developed to manage the quality of information, and how to put it to good use. The DID model has been designed for you to identify what you need and when you need it when designing business information services and as a broad guide, identifies key points in existing frameworks that are particularly useful. The model is wholly independent of all other frameworks (including BiSL and BiSL Next in which the basic design is rooted). You can choose and use whatever you wish, the model will help you to assess the validity of your choice(s) and identify strengths and weaknesses in your approach.The DID model focuses on the common languages to describe key elements of design (need and value, mission and capability), key business information perspectives (business, information/data, services and technology) and the high-level domains (governance, strategy, improvement and operation) that must be managed in order to effectively run any business.DID helps you to identify only what you need to ensure that business information design reflects what is needed by your enterprise. The model can be used entirely separately from the framework level guidance discussed and it can be used at any level in the organization. The essentials of DID are explained in two books: this book, Foundation and the Practitioner book that will be published later.

Автор: Tanios Bekaii-Saab, Bassel F. El-Rayes, Timothy M.
Название: Handbook of Gastrointestinal Cancers: Evidence-Based Treatment and Multidisciplinary Patient Care
ISBN: 0826138128 ISBN-13(EAN): 9780826138125
Издательство: Mare Nostrum (Eurospan)
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Цена: 79420.00 T
Наличие на складе: Нет в наличии.
Описание: A practical guide to the management of colorectal, pancreatic, hepatocellular, gastric, and esophageal cancers as well as other cancers of the upper and lower GI tract. The handbook focuses on treatment strategies and approaches to cancerous GI tumors that are transforming the recent oncological landscape.

Автор: Dawson Isabella
Название: Identification and Treatment of Gynecological Cancers
ISBN: 1632427419 ISBN-13(EAN): 9781632427410
Издательство: Неизвестно
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Цена: 155570.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.

Автор: Timothy Wang; James Fox; Andy Giraud
Название: The Biology of Gastric Cancers
ISBN: 1441924051 ISBN-13(EAN): 9781441924056
Издательство: Springer
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Цена: 144410.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is the first ever devoted to the basic biology of gastric cancer. Not only does it fully cover the history of clinical gastric cancer research, it also discusses cutting edge concepts in cancer stem cells, tumor microenvironment, chronic inflammation and genetic susceptibility.

Автор: Solange Peters; Benjamin Besse
Название: New Therapeutic Strategies in Lung Cancers
ISBN: 3319354094 ISBN-13(EAN): 9783319354095
Издательство: Springer
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Цена: 74530.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book offers an up-to-date review of current management of Non Small Cell Lung Cancer. It addresses all the modern issues that have been raised by the discovery of oncogenic drivers and the improvement of diagnosis and therapeutic methods.

Автор: Florian Otto; Manfred P. Lutz
Название: Early Gastrointestinal Cancers II: Rectal Cancer
ISBN: 331937866X ISBN-13(EAN): 9783319378664
Издательство: Springer
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Цена: 53100.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Recent Results in Cancer Research volume provides an up-to-date overview of the multidisciplinary management of locally confined rectal cancer as well as colorectal cancer with synchronous resectable liver metastases. The contents comprise the majority of the invited contributions from the Second St. Gallen EORTC Gastrointestinal Cancer Conference, held on 6-8 March 2014 in St. Gallen, Switzerland. Written by some of the world’s leading experts in the imaging, endoscopy, pathology, molecular biology, surgery, radiotherapy and medical oncology of rectal cancer and liver metastases, the chapters offer a comprehensive view on the latest recommendations in diagnosis and multidisciplinary treatment. Every clinician involved in the care of patients with rectal cancer will find this book interesting and helpful.

Автор: Abraham Haim; Boris A. Portnov
Название: Light Pollution as a New Risk Factor for Human Breast and Prostate Cancers
ISBN: 9401783152 ISBN-13(EAN): 9789401783156
Издательство: Springer
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Цена: 121890.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines the link between light pollution and breast and prostate cancers (BC&PC) in humans. It illustrates research hypotheses about the health effects of light pollution using the results of animal models and population-based studies.