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Molecular Biology of Human Cancers, Schulz


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Автор: Schulz   (Шульц)
Название:  Molecular Biology of Human Cancers
Перевод названия: Шульц: Молекулярная биология рака человека
ISBN: 9783031162855
Издательство: Springer
Классификация:

ISBN-10: 3031162854
Обложка/Формат: Hardback
Страницы: 542
Вес: 1.44 кг.
Дата издания: 01.03.2023
Язык: English
Издание: 2nd ed. 2023
Иллюстрации: 221 illustrations, color; 8 illustrations, black and white; xxi, 542 p. 229 illus., 221 illus. in color.
Размер: 254 x 178
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This textbook describes the most relevant molecular and biological processes in cancer, how they contribute to the development and progression of individual cancer types in humans, and how insights from molecular cancer research can be applied to improve cancer prevention, diagnostics and treatment. Part I of the textbook summarizes the current fundamental knowledge on the general properties of cancers, the causes of cancer, cancer genetics, genomics and epigenetics. Individual chapters address the functions of DNA damage and repair, oncogenes and tumor suppressors in carcinogenesis and discuss crucial mechanisms in cancer pathogenesis, such as apoptosis and replicative senescence, as well as the most relevant signal transduction pathways and regulatory networks. Part I concludes with a chapter on tumor invasion and metastasis and tumor immunology. In Part II, the most relevant mechanisms acting in individual human cancers (and subtypes) are described in more detail. This central part of the book contains individual sections on the most common human cancers highlighting the diversity in their genetic, molecular and cellular pathogenic mechanisms. How insights from molecular cancer research are translated into improvements in prevention, diagnosis, and treatment is outlined in Part III. This new edition has been extensively revised and includes in particular updated information on cancer genomics, epigenetics, viral carcinogenesis, cancer diagnostics and cancer therapy and a new chapter on lung cancers. Now more than ever, cancer research is an interdisciplinary endeavor that requires a basic knowledge of commonly used terms, facts and concepts. The aim of this book is to provide advanced students and practitioners in various disciplines with this foundation, bridging the gap between standard textbooks of molecular biology, pathology and oncology on the one hand and the specialized cancer literature on the other.
Дополнительное описание: Part I: Molecules, Genes, Cells and Mechanisms.- Chapter 1: An Introduction to Human Cancers.- Chapter 2: Cancer Genetics.- Chapter 3: DNA Damage and DNA Repair.- Chapter 4: Oncogenes.- Chapter 5: Tumor Suppressor Genes.- Chapter 6: Cancer Pathways.- Chap


Rare and uncommon gynecological cancers

Автор: Reed
Название: Rare and uncommon gynecological cancers
ISBN: 3642134912 ISBN-13(EAN): 9783642134913
Издательство: Springer
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Цена: 71730.00 T
Наличие на складе: Есть
Описание: This book is intended as a reference manual that will provide the busy clinician with up-to-date information on the diagnosis and treatment of uncommon and rare gynecological cancers. While standard textbooks briefly cover these tumors, this is intended as a more comprehensive yet easy-to-use guide. After opening chapters on epidemiology, pathology, and diagnostic imaging, the full range of infrequently encountered gynecological cancers (ovarian, uterine, cervical, vaginal, and vulval) is presented and discussed with the aid of high-quality illustrations. In each case, detailed attention is paid to both differential diagnosis and current treatment options. The book has been written by an international panel of experts and is the first to gather all the uncommon and rare gynecological cancers together within one volume.

Treatment of advanced stage cancers

Автор: G.P. Talwar
Название: Treatment of advanced stage cancers
ISBN: 8173199329 ISBN-13(EAN): 9788173199325
Издательство: Alpha Science
Рейтинг:
Цена: 40000.00 T
Наличие на складе: Есть
Описание: Treatment of Advanced Stage Cancers describes newer options for treatment of advanced liver cancers; targeting of pancreatic cancers by silencing' RNA selective killing of tumour cells expressing hCG by a high affinity, high specificity antibody linked to curcumin.

Reviewed also are the next generation of recombinant immunotoxins; herbal formulations eliminating Human Papilloma Virus (HPV) in cervical cancer cells besides immune targeting of oncogenic proteins of HPV to achieve a therapeutic vaccine for carcinoma of cervix. The book discusses optimisation of antigens for anti-cancer vaccines and optimization of Dendritic cells and viral vectors for immunotherapy. Clinical and experimental results are reported on therapeutic benefits of cancers by Mycobacterium indicus pranii. (DCGI approved vaccine for leprosy marketed as Immuvac).

Other topics covered include treatment of Chronic Myeloid Leukemia, Radiation-Enhanced Immunotherapy of Advanced cancers, Neem leaf glycoproteins regulating immune response in cancer and biology of metastasis of Head and Neck cancers. A new blood test for early diagnosis of Epithelial Ovarian Cancers is also described. The opening chapter by the Nobel Laureate David Baltimore presents elegantly the role of Micro RNAs in chronic inflammatory response and cancers.

Infectious Agents Associated Cancers: Epidemiology and Molecular Biology

Автор: Cai
Название: Infectious Agents Associated Cancers: Epidemiology and Molecular Biology
ISBN: 9811354847 ISBN-13(EAN): 9789811354847
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Поставка под заказ.
Описание: This book offers a state-of-the-art report on recent discoveries concerning viral, bacterial, and parasite infectious cancers. As such this book stimulates further research in the new area between cancers and chronic infection, and discusses the epidemiology and molecular biology of infectious causes of cancers.

Gene Therapy of Solid Cancers

Автор: Wolfgang Walther; Ulrike Stein
Название: Gene Therapy of Solid Cancers
ISBN: 1493927264 ISBN-13(EAN): 9781493927265
Издательство: Springer
Рейтинг:
Цена: 102480.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.

Molecular Basis for Therapy of AIDS-Defining Cancers

Автор: Dirk P. Dittmer; Susan E. Krown
Название: Molecular Basis for Therapy of AIDS-Defining Cancers
ISBN: 1489982000 ISBN-13(EAN): 9781489982001
Издательство: Springer
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Цена: 186330.00 T
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Описание: Cancer incidences increase in people living with HIV/AIDS. Over 2 million people currently live with HIV/AIDS in the US. This number will increase as HAART prolongs the average lifespan and as (at least in some states) the number of new HIV infections increase again. As this population ages their incidence rates for cancer will increase, as well. Recently, new rational targets for cancer therapy have emerged. But their application to the care of HIV+ patients is slow, because of concerns about the weakened immune status of the patients, because of possible drug interactions with HAART and because some of the AIDS defining cancer are rare.

Therapeutic Targeting of RAS Mutant Cancers

Автор: Edward C. Stites, Kendra Paskvan, Shumei Kato
Название: Therapeutic Targeting of RAS Mutant Cancers
ISBN: 1009073648 ISBN-13(EAN): 9781009073646
Издательство: Cambridge Academ
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Цена: 19010.00 T
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Описание: The KRAS oncogene is believed to be the most common single nucleotide variant oncogene in human cancer. Historically, efforts to target KRAS and the other RAS GTPases have struggled. More recently, efforts have focused on identifying and exploiting features unique to specific oncogenic mutations.

Hematologic Cancers: From Molecular Pathobiology to Targeted Therapeutics

Автор: Jianguo Tao; Eduardo Sotomayor
Название: Hematologic Cancers: From Molecular Pathobiology to Targeted Therapeutics
ISBN: 9400795815 ISBN-13(EAN): 9789400795815
Издательство: Springer
Рейтинг:
Цена: 156720.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book encompasses a decade of explosive growth in knowledge of the pathobiology of hematologic cancer, and offers the insight of experts from around the world on current treatment approaches and on future progress in malignant hematologic diseases.

The Biology and Prevention of Aerodigestive Tract Cancers

Автор: Guy R. Newell; Waun Ki Hong
Название: The Biology and Prevention of Aerodigestive Tract Cancers
ISBN: 1461365368 ISBN-13(EAN): 9781461365365
Издательство: Springer
Рейтинг:
Цена: 46570.00 T
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Описание: The papers contained in this volume were presented ati the Golden Jubilee Cancer Prevention Conference, "The Biology and Prevention of Aerodigestive Tract Cancers," sponsored by The University of Texas M. Aerodigestive tract cancers account for about 20% of newly diagnosed invasive cancers.

The Biology of Gastric Cancers

Автор: Timothy Wang; James Fox; Andy Giraud
Название: The Biology of Gastric Cancers
ISBN: 1441924051 ISBN-13(EAN): 9781441924056
Издательство: Springer
Рейтинг:
Цена: 144410.00 T
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Описание: This book is the first ever devoted to the basic biology of gastric cancer. Not only does it fully cover the history of clinical gastric cancer research, it also discusses cutting edge concepts in cancer stem cells, tumor microenvironment, chronic inflammation and genetic susceptibility.

Apoptosis in Hormone-Dependent Cancers

Автор: Martin Tenniswood; Horst Michna
Название: Apoptosis in Hormone-Dependent Cancers
ISBN: 3662031248 ISBN-13(EAN): 9783662031247
Издательство: Springer
Рейтинг:
Цена: 46570.00 T
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Описание: It is now widely accepted that cells have the ability to initiate a program of gene-directed death, a process called "apoptosis" which may also be used as an innovative strategy for therapeutic intervention in cancer therapy.

Early Gastrointestinal Cancers

Автор: Florian Otto; Manfred P. Lutz
Название: Early Gastrointestinal Cancers
ISBN: 3642441610 ISBN-13(EAN): 9783642441615
Издательство: Springer
Рейтинг:
Цена: 158380.00 T
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Описание: This Recent Results in Cancer Research volume contains the majority of the invited expert contributions from the First St. Gallen EORTC Gastrointestinal Cancer Conference, held on 22-24 March 2012 in St. Gallen, Switzerland. Written by some of the world’s leading experts in the field, the volume constitutes a comprehensive update on recent developments in the imaging, molecular biology, pathology, and multidisciplinary management of early cancer of the gastrointestinal tract. The latest recommendations regarding diagnosis and treatment are provided, and areas of consensus and controversy, identified. While the principal focus is on esophageal and gastric cancer, advances in the treatment of colorectal and pancreatic cancer are also discussed in some detail. This book will be of interest to every clinician involved in the care of patients with gastrointestinal malignancies.

The Genetic Basis of Haematological Cancers

Автор: Tosi
Название: The Genetic Basis of Haematological Cancers
ISBN: 0470979380 ISBN-13(EAN): 9780470979389
Издательство: Wiley
Рейтинг:
Цена: 127720.00 T
Наличие на складе: Поставка под заказ.


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