Kidney Research: Experimental Protocols, Hewitson Tim D., Smith Edward R., Holt Stephen G.

Автор: Siemionow Maria Z.
Название: Plastic and Reconstructive Surgery: Experimental Models and Research Designs
ISBN: 1447163346 ISBN-13(EAN): 9781447163343
Издательство: Springer
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Цена: 167700.00 T
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Описание: There is a paradigm shift in plastic and reconstructive surgery from the interest of developing new surgical techniques into the application of new technologies via research based studies on stem cells, tissue engineering and new field of reconstructive transplantation such as e.g.

Автор: Felix Mircea Brehar, Mircea R Gorgan
Название: Experimental Models in Glioblastoma Research
ISBN: 1633219240 ISBN-13(EAN): 9781633219243
Издательство: Nova Science
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Цена: 168950.00 T
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Описание: This book covers the basic experimental models in glioblastoma research. It starts with a description in the first two chapters of general clinical, neuroimaging and genetic data about glioblastoma (WHO grade IV glioma), which is the most frequent and the most malignant primary tumour in adults. Despite the complex treatment which includes neurosurgery, radiotherapy and chemotherapy, survival of the patients usually is between 9 and 12 months. Moreover, the surgery is not able to cure the disease due to the specific infiltrative growth pattern of glioblastoma. Therefore, laboratory research is essential in order to find new molecular and cellular therapies for this lethal disease. After shortly reviewing the modern hypothesis regarding the origin of glioblastoma in the third chapter, namely the cancer stem cells hypothesis, the author describes step-by-step in the following chapters (Chapters 4-8) the most important in vitro and in vivo models of research in glioblastoma. Chapter 4 is dedicated to the first and the essential step in any research project on glioblastoma: how to obtain good quality glioblastoma samples, how to prepare the samples and how to store the samples long-term for subsequent research. Open surgery and the image-guided stereotactic technique are also described in this chapter. After obtaining the tumour samples, the next step is to initiate the primary cells cultures. These in vitro techniques (either serum conditioning cell cultures and tumour stem cells cultures) will be discussed in detail in Chapters 5 and 6. Usually the new molecules with antitumor activity are tested in vitro on both primary glioblastoma cells cultures but also on glioblastoma cells lines in order to obtain a better standardised results. The next chapter, Chapter 7 is dedicated to in vivo techniques, which are required for testing the anti-tumoural effect of the new molecules before starting with the clinical trials. The author describes in detail the techniques of stereotactic intracranial inoculation of glioblastoma cells (either glioblastoma cell lines or glioblastoma-derived tumour stem cells) and the main growth patterns of the intracranial glioblastoma xenografts obtained using these techniques. Another technique very useful for exploring in real time the migratory glioblastoma cells is the organotypic brain slice cultures which is described in the last chapter of the book.

Автор: Dwek
Название: Metastasis Research Protocols
ISBN: 1461482437 ISBN-13(EAN): 9781461482437
Издательство: Springer
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Цена: 139750.00 T
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Описание: This new edition offers updates and important new techniques for illuminating the processes underlying research on metastasis. Presents techniques applicable to living cells and tissues, to cell behavior in vitro, to animal models and mathematical constructs.

Автор: Idris
Название: Bone Research Protocols
ISBN: 1493989960 ISBN-13(EAN): 9781493989966
Издательство: Springer
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Цена: 204970.00 T
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Описание:

Part I: In Vitro Culture of Bone Cells

Автор: Jacobsen, Kathryn H.
Название: Introduction to Health Research Methods: A Practical Guide [With Access Code]
ISBN: 1284094383 ISBN-13(EAN): 9781284094381
Издательство: NBN International
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Цена: 66160.00 T
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Описание: Demystify The Research Process And Empowers Your Students To Conduct Their Own Original Research Projects With This Clear, Practical, And Straightforward Text. In Five Sections, Introduction To Health Research Methods Describes The Entire Research Process Beginning With The Identification Of A Research Question And The Selection Of A Study Approach, Proceeding Through The Collection And Analysis Of Data And The Preparation Of A Formal Scientific Report, And Ending With Academic And Professional Presentations And Publishing. By Breaking The Research Process Down Into Manageable Steps, Introduction To Health Research Methods Communicates The Excitement And Importance Of Health Research—And Encourages Readers To Make Their Own Contribution To Improving The Health Of Individuals And Communities Through Research. The Second Edition Is A Thorough Update That Offers: •NEW Chapter On Research Funding That Explains How To Find Grant Opportunities, Write Proposals, And Manage Grants •Many New Examples Of Research Types Such As Monitoring And Evaluation (M&E) And Health Services Research •Coverage Of New Topics Including Professional Organizations And Professional Development Opportunities, Qualitative Studies, Big Data, And Health Informatics •Expanded Coverage Of Research Ethics And Laws •A Comprehensive Walk Through Of Key Writing Strategies That Includes Timelines For Abstract Submission, Conference Presentations, And Article Submissions •Improved And Expanded Coverage Of Tertiary Analyses To Include Examples Of Eligibility Criteria, Quality Assessment, And Qualitative And Quantitative Analysis Methods

Автор: Herzog, Michael H. Francis, Gregory Clarke, Aaron
Название: Understanding statistics and experimental design
ISBN: 3030034984 ISBN-13(EAN): 9783030034986
Издательство: Springer
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Цена: 46570.00 T
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Описание: This open access textbook provides the background needed to correctly use, interpret and understand statistics and statistical data in diverse settings. Part III provides insight into meta-statistics (statistics of statistics) and demonstrates why experiments often do not replicate.

Автор: Tim D. Hewitson; Gavin J. Becker (Eds.)
Название: Kidney Research
ISBN: 1588299457 ISBN-13(EAN): 9781588299451
Издательство: Springer
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Цена: 144410.00 T
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Описание: As the expense of treating a growing number of end-stage kidney disease patients increases, greater attention has been paid to prevention and early treatment. This book aids researchers by providing a number of specialized techniques developed to examine this intricate system.

Автор: Tim D. Hewitson; Edward R. Smith; Stephen G. Holt
Название: Kidney Research
ISBN: 1493933515 ISBN-13(EAN): 9781493933518
Издательство: Springer
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Цена: 130430.00 T
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Описание: This second edition expands upon the previous volume with additional emphasis on recent innovation in basic renal research and has a more holistic approach on associated disorders such as complications associated with peritoneal dialysis, ischemic acute kidney injury, the sympathetic nervous system, and vascular calcification.

Автор: Tim D. Hewitson; Gavin J. Becker
Название: Kidney Research
ISBN: 149395640X ISBN-13(EAN): 9781493956401
Издательство: Springer
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Цена: 130430.00 T
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Описание: As the expense of treating a growing number of end-stage kidney disease patients increases, greater attention has been paid to prevention and early treatment. The study of renal disease, however, suffers due to the complex nature of renal anatomy and physiology and the plethora of different cell types found in the kidney. In Kidney Research: Experimental Protocols, top experts in the field seek to aid researchers by providing a number of specialized techniques developed to examine this intricate system. Through both well-established and novel methods, this volume explores the preparation and culture of the main cell types used to study renal disease mechanisms, the common animal models used to mimic the various forms of human renal disease, and specific applications and techniques used in vivo and in vitro. Written in the highly successful Methods in Molecular Biology™ series format, the chapters contain step-by-step, readily reproducible laboratory protocols, lists of the necessary materials and reagents, and tips on troubleshooting and avoiding known pitfalls. Essential and cutting-edge, Kidney Research: Experimental Protocols delivers invaluable guidance to new and experienced laboratory researchers delving into the sophisticated study of the kidney.

Автор: Beckett Dakota
Название: New Frontiers in Chronic Kidney Disease Research
ISBN: 1632416611 ISBN-13(EAN): 9781632416612
Издательство: Неизвестно
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Цена: 160930.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.