Автор: Hulley Название: Designing clinical research ISBN: 1608318044 ISBN-13(EAN): 9781608318049 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 82370.00 T Наличие на складе: Нет в наличии. Описание: Designing Clinical Research has been extensively revised and continues to set the standard as a practical guide for doctors, nurses, pharmacists, and other health professionals involved in all forms of clinical, translational, and public health research. It presents advanced epidemiologic concepts in a reader-friendly way, and suggests common sense approaches to the challenging judgments involved in designing, funding, and implementing. New to this edition: Expanded and updated content in every chapter, with new material on: • non-inferiority trials for comparative effectiveness research • incidence-density case-control studies • confounding and effect modification • diagnostic test studies to inform prediction rules • ethical aspects of whole genome sequencing • automated data management approaches • new NIH grant-writing requirements Color format, and Electronic access, powered by Inkling™ as a free companion to the text • viewable through your browser or as a download to tablet or smartphone • the complete text with optimized navigation • note-sharing, highlighting and bookmarking capability • cross-linking of references and content • rapid search options linked to the new glossary
Автор: Tim D. Hewitson; Gavin J. Becker (Eds.) Название: Kidney Research ISBN: 1588299457 ISBN-13(EAN): 9781588299451 Издательство: Springer Рейтинг: Цена: 144410.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: As the expense of treating a growing number of end-stage kidney disease patients increases, greater attention has been paid to prevention and early treatment. This book aids researchers by providing a number of specialized techniques developed to examine this intricate system.
Автор: Tim D. Hewitson; Edward R. Smith; Stephen G. Holt Название: Kidney Research ISBN: 1493933515 ISBN-13(EAN): 9781493933518 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This second edition expands upon the previous volume with additional emphasis on recent innovation in basic renal research and has a more holistic approach on associated disorders such as complications associated with peritoneal dialysis, ischemic acute kidney injury, the sympathetic nervous system, and vascular calcification.
Автор: Robert J. Nordstrom (Editor) Название: Translational Research In Biophotonics ISBN: 162841068X ISBN-13(EAN): 9781628410686 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 75770.00 T Наличие на складе: Невозможна поставка. Описание: Translational research transforms scientific discoveries arising from laboratory, clinical, or population studies into clinical applications to reduce cancer incidence, morbidity, and mortality. Optical imaging in medicine is a rapidly growing field, showing promise for delivering new low-cost, point-of-care capabilities with dramatic increases in measurement sensitivity. Unfortunately, despite all of the promises offered by optical imaging, few concepts are making it through the translational pipeline from laboratory demonstration to commercialization for clinical use.The National Cancer Institute of the National Institutes of Health focused a research program on the study of optical imaging for translational advancement into clinical applications for reduction of cancer morbidity and mortality. This book highlights the translational activities of four research groups created for this program, called the Network for Translational Research (NTR). The research leads were Lihong Wang, Eva Sevick-Muraca, Thomas D. Wang, and Christopher Contag. While detailed insight into the nature of the research accomplished at each of these centers is provided, the purpose of this text is to demonstrate that the NTR centers with their industrial partners created significant pathways along the direction of translational research, and that these pathways can now be followed by other researchers seeking to bring these ideas closer to commercial reality. This book will be useful for academic researchers interested in taking concepts and devices beyond the usual ""proof-of-principle"" barrier into areas concerned with good laboratory practices and good manufacturing practices in order to prepare for the translation to FDA discussions.
Автор: Shneiderman Ben Название: The New ABCs of Research ISBN: 0198758839 ISBN-13(EAN): 9780198758839 Издательство: Oxford Academ Рейтинг: Цена: 38530.00 T Наличие на складе: Нет в наличии. Описание: This book is a guide for junior researchers, and a manifesto for senior researchers and policy makers about how to update policies to respond to the immense challenges of our times. The guiding principles are to combine applied and basic research in ways that use the methods of science, engineering, and design.
Автор: Curtis, Michael Название: Research in the Biomedical Sciences ISBN: 0128047259 ISBN-13(EAN): 9780128047255 Издательство: Elsevier Science Рейтинг: Цена: 62830.00 T Наличие на складе: Нет в наличии. Описание:
Research in the Biomedical Sciences: Transparent and Reproducible documents the widespread concerns related to reproducibility in biomedical research and provides a best practices guide to effective and transparent hypothesis generation, experimental design, reagent standardization (including validation and authentication), statistical analysis, and data reporting.
The book addresses issues in the perceived value of the existing peer review process and calls for the need for improved transparency in data reporting. It reflects new guidelines for publication that include manuscript checklists, replication/reproducibility initiatives, and the potential consequences for the biomedical research community and societal health and well-being if training, mentoring, and funding of new generations of researchers and incentives for publications are not improved.
This book offers real world examples, insights, and solutions to provide a thought-provoking and timely resource for all those learning about, or engaged in, performing and supervising research across the biomedical sciences.
Provides a "big picture" perspective that includes the scope of the replicability issue and covers initiatives that have the potential to act as effective solutions
Offers real world research context for transparent, replicable experimental design and execution and reporting of biomedical research with the potential to address aspects of the translational gap in drug discovery
Highlights the importance of reproducibility and the necessary changes in biomedical and pharmaceutical research training and incentives to ensure sustainability
Автор: Rutkove, S. B. Название: Biomedical Research ISBN: 1493936530 ISBN-13(EAN): 9781493936533 Издательство: Springer Рейтинг: Цена: 69870.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This comprehensive yet concise book introduces people at all levels of training—undergraduate, graduate, and medical students, residents, fellows, and junior faculty—to the basic joys and challenges of biomedical research. By discussing many key research issues, would-be and early-stage academics will not only be better informed about the world of biomedical research, but will learn a basic set of instructions to help jumpstart their careers. Biomedical Research: An Insider’s Guide is divided into five sections. The first focuses on decision points regarding whether or not to enter research and if so what type: basic, clinical, or translational. The second section focuses on the practicalities of pursuing medical research, including institutional review boards and animal care committees as well general suggestions regarding idea generation and collaboration. The third section covers a core aspect of research: writing—detailing the evolution of both grants and papers. The fourth section addresses a range of issues, including conferencing to patents to working with industry to obtaining philanthropic support. The final section deals with all-important broader life issues from job choices to being a mentor to thoughts on how to keep the big picture front and center. An invaluable resource that offers insightful, practical advice, Biomedical Research: An Insider’s Guide reveals how biomedical research can be both challenging and truly rewarding.
Автор: L.A. Osterman Название: Methods of Protein and Nucleic Acid Research ISBN: 3642874878 ISBN-13(EAN): 9783642874871 Издательство: Springer Рейтинг: Цена: 113190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This method enables separation of macromolecules according to characteristic features such as size (or molecular weight), shape, secondary structure and electric charge and these parameters can in- fluence electrophoretic properties either separately or jointly.
Автор: Edelstein, Charles L. Название: Biomarkers of Kidney Disease ISBN: 0128030143 ISBN-13(EAN): 9780128030141 Издательство: Elsevier Science Рейтинг: Цена: 97690.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Biomarkers of Kidney Disease, Second Edition, focuses on the basic and clinical research of biomarkers in common kidney diseases, detailing the characteristics of an ideal biomarker. The latest techniques for biomarker detection, including metabolomics and proteomics are covered in the book.
This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical analysis, transplantation, and preeclampsia. New chapters include biomarkers of cardiovascular disease in patients with CKD, biomarkers of Polycystic Kidney Disease, and biomarkers and the role of nanomedicine.
Автор: Hickson Название: Research Handbook for Health Care Professionals ISBN: 1405177373 ISBN-13(EAN): 9781405177375 Издательство: Wiley Рейтинг: Цена: 43240.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The Research Handbook for Health Care Professionals is the essential guide to the entire research process for students and practitioners alike.
Автор: Wilkins Название: Proteome Research 1997 ISBN: 3540627537 ISBN-13(EAN): 9783540627531 Издательство: Springer Цена: 10260.00 T Наличие на складе: Нет в наличии. Описание: Recent advances in two-dimensional electrophoresis, protein microanalysis and bioinformatics have made the large-scale, systematic analysis of proteins and their post-translational modifications from any tissue or organism possible. This approach has acquired the name "Proteome Research", and can be considered as the core of functional genomics. The results of proteome analysis show which genes are expressed, how the protein products are modified, and how they interact, making proteome research of fundamental importance for the biologist, clinician, and pharmaceutical industry.
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