Gene silencing: approaches, applications and updates, Shiv Sanjeevi Sripathi

Автор: Shiv Sanjeevi Sripathi
Название: Gene Silencing: Approaches, Applications and Updates
ISBN: 1774076969 ISBN-13(EAN): 9781774076965
Издательство: Mare Nostrum (Eurospan)
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Цена: 151530.00 T
Наличие на складе: Нет в наличии.
Описание: Researchers are using the property of RNA interference to silence several genes that have opened up the use of siRNAs in the analysis of the various genes that are involved or implicated in diseases. This book is a concise presentation of RNA silencing: the mechanisms involved have been discussed along with figures.

Автор: Kang, Mo K.
Название: Endodontics: Clinical and Scientific Updates, An Issue of Dental Clinics of North America,61-1. -Elsevier Science
ISBN: 0323482589 ISBN-13(EAN): 9780323482585
Издательство: Elsevier Science
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Цена: 90380.00 T
Наличие на складе: Нет в наличии.
Описание: This issue of Dental Clinics of North America focuses on Endodontics, and is edited by Dr. Mo Kang. Articles will include: Endodontic Microbiology and Pathobiology: Current State of Knowledge; Conventional Endodontic Therapies: Innovation in Biomechanics; Endodontic Retreatments: Non-surgical and Surgical Approaches; Pain Management in Endodontics: Opportunity for New Therapeutics; Pulpal Management of Immature Teeth: Use of New Biomaterials for Conservative Therapies; Innovation in Bioactive Restorative Materials; Topic in Regenerative Endodontics; Biological Molecules for the Regeneration of the Pulp-dentin Complex; Cell Homing Approach in Endodontic Regeneration; Stem Cell Therapies for Oral and Systemic Diseases; Endodontic Treatment Outcomes, and more!

Автор: Nimesh, Surendra Ramesh, Chandra
Название: Theory, techniques and applications of nanotechnology in gene silencing
ISBN: 8792329837 ISBN-13(EAN): 9788792329837
Издательство: Taylor&Francis
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Цена: 107190.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Gene silencing mediated through short interfering RNAs (siRNAs) is rapidly emerging as a new class of therapeutics for the treatment of inherited and acquired diseases. However, poor cellular uptake and instability in physiological conditions limits its therapeutic potential, hence there arises a need to develop a delivery system which can protect and efficiently transport siRNA to the target cells. Nanotechnology based non-viral vectors have been proposed as a potential alternate. Various polymeric nanoparticles have been shown as suitable delivery candidates with high cellular uptake efficiencies and advantage of reduced cytotoxicity. These delivery vectors form condensed complexes with siRNA which in turn provides protection to siRNA from enzymatic degradation and further leads to enhanced tissue and cellular targeting. Nanoparticles prepared from various polymers like polyethylenimine, chitosan have been largely exploited, as they bear several advantages such as, easy manipulatibility, high stability, low cost and high payload. Though numerous publications have appeared in the literature, there was still need to get more information under one roof, as book compilation which could provide a systematic account of all the aspects of nanotechnology mediated gene silencing right from the preparation of nanoparticles to in vitro and in vivo characterization followed by various applications in vitro and in vivo models. This book focuses on various aspects of nanotechnology based gene silencing. The initial chapters detail the techniques available for in vitro and in vivo characterization of nanoparticles. In the later chapters, exhaustive details about various polymeric systems employed for gene silencing has been accounted.The important topics discussed in the book include: Introduction to NanotechnologyPhysicochemical Characterization of NanoparticlesIn Vitro and In Vivo Characterization of NanoparticlesConcept and Barriers to Gene SilencingNanoparticles Mediated Targeted siRNA deliveryPolymers for siRNA DeliveryChitosanPolyethyleniminePoly-L-lysineAtelocollagenProtamineDendrimersCyclodextrinPoly (D, L-lactide-co-glycolide)Nanomaterials for siRNA delivery.

Название: Sirna and mirna gene silencing
ISBN: 1617379085 ISBN-13(EAN): 9781617379086
Издательство: Springer
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Цена: 135090.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this easy-to-use and up-to-date volume, expert researchers explore the most recent advances in siRNA design, expression, delivery, in vivo imaging, and methods. The aim is to minimize siRNA`s unwanted effects and promote successful use in patients.

Автор: Vincent Courdavault; S?bastien Besseau
Название: Virus-Induced Gene Silencing in Plants
ISBN: 1071607502 ISBN-13(EAN): 9781071607503
Издательство: Springer
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Цена: 102480.00 T
Наличие на складе: Нет в наличии.
Описание: This volume aims at providing a complete and updated overview of gene downregulation in plants performed through virus-induced gene silencing (VIGS).

Автор: Peter Meyer
Название: Gene Silencing in Higher Plants and Related Phenomena in Other Eukaryotes
ISBN: 3642791476 ISBN-13(EAN): 9783642791475
Издательство: Springer
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Цена: 121110.00 T
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Описание: In recent years several different gene silencing phenomena have been discovered in plants. By providing a comparative update on gene silencing effects in different eukaryotes, this book should stimulate communication among scientists working in diverse areas of eukaryotic gene regulation.

Автор: J. Paszkowski
Название: Homologous Recombination and Gene Silencing in Plants
ISBN: 9401044783 ISBN-13(EAN): 9789401044783
Издательство: Springer
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Цена: 186330.00 T
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Автор: Annette Becker
Название: Virus-Induced Gene Silencing
ISBN: 1493959425 ISBN-13(EAN): 9781493959426
Издательство: Springer
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Цена: 111790.00 T
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Описание: Maintaining the high standards and detailed practical guidance of Springer`s Methods in Molecular Biology series, this book has comprehensive, step-by-step protocols on the fast and reliable use of viruses to induce down-regulation of target gene expression.

Автор: Kirankumar S. Mysore; Muthappa Senthil-Kumar
Название: Plant Gene Silencing
ISBN: 1493924524 ISBN-13(EAN): 9781493924523
Издательство: Springer
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Цена: 139750.00 T
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Описание: In addition to these review chapters, this book includes methodology for virus-induced gene silencing (VIGS) in various different plant species, understanding plant stress responses using VIGS, miRNA identification, DNA interference, host-induced gene silencing, use of artificial miRNAs for gene silencing, high throughput RNAi, and more.

Автор: J. Paszkowski
Название: Homologous Recombination and Gene Silencing in Plants
ISBN: 0792327047 ISBN-13(EAN): 9780792327042
Издательство: Springer
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Цена: 231990.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This text summarizes current knowledge and hypotheses about the frequencies and mechanisms of mitochondrial, plastid, nuclear and viral recombination and the inactivation of repeated genes in plants. It is addressed to scientists working in plant biology and recombination, and biology students.