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RNA Polymerases as Molecular Motors: On the Road, 


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Название:  RNA Polymerases as Molecular Motors: On the Road
ISBN: 9781788013659
Издательство: Royal Society of Chemistry
Издательство: Royal Society of Chemistry
Классификация:



ISBN-10: 1788013654
Обложка/Формат: Hardback
Страницы: 294
Вес: 0.55 кг.
Дата издания: 15.12.2021
Серия: Chemical biology
Язык: English
Издание: 2 new edition
Иллюстрации: No
Размер: 236 x 158 x 23
Читательская аудитория: Professional & vocational
Подзаголовок: On the road
Рейтинг:
Поставляется из: США
Описание: This book, written by expert scientists in the field, analyses how these diverse fields of research interact on a specific example - RNA polymerase.

Human dna polymerases: biology, medicine and biotechnology

Автор: Hubscher, Ulrich (univ Of Zurich-irchel, Switzerland) Maga, Giovanni (inst Of Molecular Genetics Igm-cnr, Italy) Villani, Giuseppe (cnrs-paul Sabatier
Название: Human dna polymerases: biology, medicine and biotechnology
ISBN: 9813226404 ISBN-13(EAN): 9789813226401
Издательство: World Scientific Publishing
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Цена: 146790.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex processes that maintain genetic integrity. Besides their tasks in vivo, DNA polymerases are the workhorses in numerous biotechnology applications such as the polymerase chain reaction (PCR), cDNA cloning, next generation sequencing, nucleic acids based diagnostics and in techniques to analyze ancient and otherwise damaged DNA (e.g. for forensic applications). Moreover, some diseases are related to DNA polymerase defects and chemotherapy through inhibition of DNA polymerases is used to fight HIV, Herpes and Hepatitis B and C infections. This book focuses on (i) biology of DNA polymerases, (ii) medical aspects of DNA polymerases and (iii) biotechnological applications of DNA polymerases. It is intended for a wide audience from basic scientists, to diagnostic laboratories, to companies and to clinicians, who seek a better understanding and the practical use of these fascinating enzymes.


Nucleic Acid Polymerases

Автор: Katsuhiko S. Murakami; Michael A. Trakselis
Название: Nucleic Acid Polymerases
ISBN: 3642397956 ISBN-13(EAN): 9783642397950
Издательство: Springer
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Цена: 156720.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a review of the multitude of nucleic acid polymerases, including DNA and RNA polymerases from Archea, Bacteria and Eukaryota, mitochondrial and viral polymerases, and other specialized polymerases.

Nucleic Acid Polymerases

Автор: Katsuhiko S. Murakami; Michael A. Trakselis
Название: Nucleic Acid Polymerases
ISBN: 3662509989 ISBN-13(EAN): 9783662509982
Издательство: Springer
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Цена: 130590.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a review of the multitude of nucleic acid polymerases, including DNA and RNA polymerases from Archea, Bacteria and Eukaryota, mitochondrial and viral polymerases, and other specialized polymerases.

Applications of Polymerase Chain Reaction

Автор: Sarika Garg
Название: Applications of Polymerase Chain Reaction
ISBN: 1773611232 ISBN-13(EAN): 9781773611235
Издательство: Mare Nostrum (Eurospan)
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Цена: 160770.00 T
Наличие на складе: Невозможна поставка.
Описание: Integrates the latest studies related to PCR and its applications. Exploring an introduction to polymerase chain reaction, the application of reverse transcriptase-polymerase chain reaction (RT-PCR) in the rapid detection of pathogen in water samples and PCR methods for accurate and rapid screening of the genetically modified organisms in foods are presented.

Poly(ADP-ribose) Polymerase

Автор: Alexei V Tulin
Название: Poly(ADP-ribose) Polymerase
ISBN: 1493962159 ISBN-13(EAN): 9781493962150
Издательство: Springer
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Цена: 153720.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology (TM) book shows how PARP proteins act in normal and pathogenic development of organisms, advances knowledge of developmental pathways regulation, and furthers development of new drugs and methods to target PARP-dependent processes.

Poly(ADP-Ribose) Polymerase

Автор: Alexei V. Tulin
Название: Poly(ADP-Ribose) Polymerase
ISBN: 1493969927 ISBN-13(EAN): 9781493969920
Издательство: Springer
Рейтинг:
Цена: 116450.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

Part I: Detection and Quantification of pADPr

1. Quantitation of Poly(ADP-ribose) by Isotope Dilution Mass Spectrometry

Tabea Zubel, Rita Martello, Alexander Bьrkle, and Aswin Mangerich

2. Quantification of PARP Activity in Human Tissues: Ex Vivo Assays in Blood Cells and Immunohistochemistry in Human Biopsies

Eszter M. Horvath, Zsuzsanna K. Zsengellйr, and Csaba Szabo

3. Detecting and Quantifying pADPr In Vivo

Yi-Chen Lai, Rajesh K. Aneja, Margaret A. Satchell, and Robert S.B. Clark

4. Compartment-Specific Poly-ADP-Ribose Formation as a Biosensor for Subcellular NAD Pools

Magali R. VanLinden, Marc Niere, Andrey A. Nikiforov, Mathias Ziegler, and Christian Dцlle

5. Cell Cycle Resolved Measurements of Poly(ADP-ribose) Formation and DNA Damage Signaling by Quantitative Image-Based Cytometry

Jone Michelena and Matthias Altmeyer

Part II: Identification of Protein Targets

6. Detecting Protein ADP-Ribosylation Using a Clickable Aminooxy Probe

Rory K. Morgan and Michael S. Cohen

7. ADP-Ribosylated Peptide Enrichment and Site Identification: The Phosphodiesterase-Based Method

Casey M. Daniels, Shao-En Ong, and Anthony K.L. Leung

8. Using Clickable NAD+ Analogues to Label Substrate Proteins of PARPs

Lu Zhang and Hening Lin

9. Identification of Protein Substrates of Specific PARP Enzymes Using Analog-Sensitive PARP Mutants and a 'Clickable' NAD+ Analog

Bryan A. Gibson and W. Lee Kraus

10. Identification of ADP-Ribose Acceptor Sites on In Vitro Modified Proteins by Liquid Chromatography - Tandem Mass Spectrometry

Mario Leutert, Vera Bilan, Peter Gehrig, and Michael O. Hottiger

11. Proteome-Wide Identification of In Vivo ADP-Ribose Acceptor Sites by Liquid Chromatography -Tandem Mass Spectrometry

Sara C. Larsen, Mario Leutert, Vera Bilan, Rita Martello, Stephanie Jungmichel, Clifford Young, Michael O. Hottiger, and Michael L. Nielsen

Part III: Functional Analysis

12. Poly(ADP-Ribose)-Dependent Chromatin Remodeling in DNA Repair

Thйo Lebeaupin, Rebecca Smith, Sйbastien Huet, and Gyula Timinszky

13. Methods to Assess the Role of Poly(ADP-Ribose) Polymerases in Regulating Mitochondrial Oxidative Function

Edit Mikу, Tьnde Kovбcs, Tamбs Fodor, and Pйter Bai

14. Approaches for Investigating Translational Regulation Controlled by PARP1: Biotin-Based UV-Crosslinking and Luciferase Reporter Assay

Yingbiao Ji

15. Methodology to Identify Poly-ADP-Ribose Polymerase 1 (PARP1)

RNA Polymerase III Transcription

Автор: Robert J. White
Название: RNA Polymerase III Transcription
ISBN: 3662035200 ISBN-13(EAN): 9783662035207
Издательство: Springer
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Цена: 93160.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This monograph reviews and summarizes the substantial body of work that has been published on the transcription by polymerase III over the past 5 years.

Quantitation of mRNA by Polymerase Chain Reaction

Автор: Thomas K?hler; Dirk La?ner; Anne-Katrin Rost; Barb
Название: Quantitation of mRNA by Polymerase Chain Reaction
ISBN: 3642797148 ISBN-13(EAN): 9783642797149
Издательство: Springer
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Цена: 113190.00 T
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Описание: In this laboratory "cook-book", the authors provide a concise guide to PCR-based techniques to quantify nucleic acids in biological and clinical samples using exclusively nonradioactive detection methods, e.g.

Diagnosis of Human Viruses by Polymerase Chain Reaction Technology

Автор: Yechiel Becker; Gholamreza Darai
Название: Diagnosis of Human Viruses by Polymerase Chain Reaction Technology
ISBN: 3642847684 ISBN-13(EAN): 9783642847684
Издательство: Springer
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Цена: 121110.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Viruses which integrate into the cellular DNA (such as human immunodeficiency virus, HIV -1, or hepatitis B virus) are difficult to identify by molecular techniques, while viruses which exist in the clinical material in low concentrations are even more formidable to identify.

PCR Topics

Автор: Arndt Rolfs; Hermann C. Schumacher; Peter Marx
Название: PCR Topics
ISBN: 3540529349 ISBN-13(EAN): 9783540529347
Издательство: Springer
Рейтинг:
Цена: 102480.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The Polymerase Chain Reaction (PCR), a simple method for amplifying nucleic acids in vitro, has revolutionized the technical development of molecular biology and immunology. This study surveys the present usage and future significance of PCR, and its potential for disease identification.

PCR - Polymerase-Kettenreaktion

Автор: Hans-Joachim M?ller; Daniel Ruben Prange
Название: PCR - Polymerase-Kettenreaktion
ISBN: 3662482355 ISBN-13(EAN): 9783662482353
Издательство: Springer
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Цена: 60940.00 T
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Описание:

Einleitung.- Allgemeine PCR-Parameter.- PCR als Detektionsmethode.- PCR als Klonierungsmethode.- PCR fьr die Standard-Klonierung.- T/A-Cloning.- Ligase-unabhдngige-Klonierung (LIC).- UNG-Klonierung.- Surf-Klonierung.- Megaprime-PCR.- RT-PCR.- RACE-PCR.- Quantitative PCR.- Real-Time-PCR.- Colony-PCR.- PCR zur Mutationsanalyse.- Nested-PCR.- DOP-PCR.- Alu- (IRS) PCR.- PCR-Optimierung.- 1-Sekunden-PCR.- Long Distance-PCR.- Genomtypisierung mit der PCR.- Differential Display PCR Firmenverzeichnis Internet-Adressen rund um die PCR Sachregister.


Polymerase Chain Reaction: Theory and Technology

Автор: Behlke Mark a., Berghof-Jager Kornelia, Et Al
Название: Polymerase Chain Reaction: Theory and Technology
ISBN: 1912530244 ISBN-13(EAN): 9781912530243
Издательство: Неизвестно
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Цена: 306530.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

The polymerase chain reaction (PCR) is a powerful research tool used in many scientific disciplines. It is also used for detection and testing in areas such as food microbiology, environmental microbiology, biotechnology, industrial microbiology, veterinary and medical diagnostics. This indispensable manual is a compilation of review articles written by experts in the field of PCR technology. Topics covered include: principles of PCR, fluorescent chemistries, instrumentation, quantification strategies, extraction and purification of nucleic acids, sample preparation, controls for validation, primers and probes, standardization of methods, MIQE guidelines, mRNA expression and PCR arrays. This book provides a comprehensive overview of PCR theory, instrumentation and methods. The book represents an excellent, detailed guide for anyone interested in the development and use of PCR technology. It is a recommended purchase for all microbiology and molecular biology laboratories and university libraries.



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