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Diagnosis of Human Viruses by Polymerase Chain Reaction Technology, Yechiel Becker; Gholamreza Darai


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Автор: Yechiel Becker; Gholamreza Darai
Название:  Diagnosis of Human Viruses by Polymerase Chain Reaction Technology
ISBN: 9783642847684
Издательство: Springer
Классификация:




ISBN-10: 3642847684
Обложка/Формат: Paperback
Страницы: 426
Вес: 0.62 кг.
Дата издания: 09.02.2012
Серия: Frontiers of Virology
Язык: English
Размер: 234 x 156 x 23
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Viruses which integrate into the cellular DNA (such as human immunodeficiency virus, HIV -1, or hepatitis B virus) are difficult to identify by molecular techniques, while viruses which exist in the clinical material in low concentrations are even more formidable to identify.

Poly(ADP-Ribose) Polymerase

Автор: Alexei V. Tulin
Название: Poly(ADP-Ribose) Polymerase
ISBN: 1493969927 ISBN-13(EAN): 9781493969920
Издательство: Springer
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Цена: 116450.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

Part I: Detection and Quantification of pADPr

1. Quantitation of Poly(ADP-ribose) by Isotope Dilution Mass Spectrometry

Tabea Zubel, Rita Martello, Alexander Bьrkle, and Aswin Mangerich

2. Quantification of PARP Activity in Human Tissues: Ex Vivo Assays in Blood Cells and Immunohistochemistry in Human Biopsies

Eszter M. Horvath, Zsuzsanna K. Zsengellйr, and Csaba Szabo

3. Detecting and Quantifying pADPr In Vivo

Yi-Chen Lai, Rajesh K. Aneja, Margaret A. Satchell, and Robert S.B. Clark

4. Compartment-Specific Poly-ADP-Ribose Formation as a Biosensor for Subcellular NAD Pools

Magali R. VanLinden, Marc Niere, Andrey A. Nikiforov, Mathias Ziegler, and Christian Dцlle

5. Cell Cycle Resolved Measurements of Poly(ADP-ribose) Formation and DNA Damage Signaling by Quantitative Image-Based Cytometry

Jone Michelena and Matthias Altmeyer

Part II: Identification of Protein Targets

6. Detecting Protein ADP-Ribosylation Using a Clickable Aminooxy Probe

Rory K. Morgan and Michael S. Cohen

7. ADP-Ribosylated Peptide Enrichment and Site Identification: The Phosphodiesterase-Based Method

Casey M. Daniels, Shao-En Ong, and Anthony K.L. Leung

8. Using Clickable NAD+ Analogues to Label Substrate Proteins of PARPs

Lu Zhang and Hening Lin

9. Identification of Protein Substrates of Specific PARP Enzymes Using Analog-Sensitive PARP Mutants and a 'Clickable' NAD+ Analog

Bryan A. Gibson and W. Lee Kraus

10. Identification of ADP-Ribose Acceptor Sites on In Vitro Modified Proteins by Liquid Chromatography - Tandem Mass Spectrometry

Mario Leutert, Vera Bilan, Peter Gehrig, and Michael O. Hottiger

11. Proteome-Wide Identification of In Vivo ADP-Ribose Acceptor Sites by Liquid Chromatography -Tandem Mass Spectrometry

Sara C. Larsen, Mario Leutert, Vera Bilan, Rita Martello, Stephanie Jungmichel, Clifford Young, Michael O. Hottiger, and Michael L. Nielsen

Part III: Functional Analysis

12. Poly(ADP-Ribose)-Dependent Chromatin Remodeling in DNA Repair

Thйo Lebeaupin, Rebecca Smith, Sйbastien Huet, and Gyula Timinszky

13. Methods to Assess the Role of Poly(ADP-Ribose) Polymerases in Regulating Mitochondrial Oxidative Function

Edit Mikу, Tьnde Kovбcs, Tamбs Fodor, and Pйter Bai

14. Approaches for Investigating Translational Regulation Controlled by PARP1: Biotin-Based UV-Crosslinking and Luciferase Reporter Assay

Yingbiao Ji

15. Methodology to Identify Poly-ADP-Ribose Polymerase 1 (PARP1)

Viruses: A Very Short Introduction

Автор: Crawford, Dorothy H.
Название: Viruses: A Very Short Introduction
ISBN: 0199574855 ISBN-13(EAN): 9780199574858
Издательство: Oxford Academ
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Цена: 8440.00 T
Наличие на складе: Поставка под заказ.
Описание: From modern pandemics such as HIV, swine flu and SARS, to stories of vaccination and antiviral drugs, this Very Short Introduction charts man`s struggle against viruses. Outlining their origins, structure, and method of infection, Dorothy Crawford explores the vast variety of viruses, asking if we can live in harmony with them in the future.

Quantitation of mRNA by Polymerase Chain Reaction

Автор: Thomas K?hler; Dirk La?ner; Anne-Katrin Rost; Barb
Название: Quantitation of mRNA by Polymerase Chain Reaction
ISBN: 3642797148 ISBN-13(EAN): 9783642797149
Издательство: Springer
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Цена: 113190.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this laboratory "cook-book", the authors provide a concise guide to PCR-based techniques to quantify nucleic acids in biological and clinical samples using exclusively nonradioactive detection methods, e.g.

Poly(ADP-ribose) Polymerase

Автор: Alexei V Tulin
Название: Poly(ADP-ribose) Polymerase
ISBN: 1493962159 ISBN-13(EAN): 9781493962150
Издательство: Springer
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Цена: 153720.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology (TM) book shows how PARP proteins act in normal and pathogenic development of organisms, advances knowledge of developmental pathways regulation, and furthers development of new drugs and methods to target PARP-dependent processes.

RNA Polymerase III Transcription

Автор: Robert J. White
Название: RNA Polymerase III Transcription
ISBN: 3662035200 ISBN-13(EAN): 9783662035207
Издательство: Springer
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Цена: 93160.00 T
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Описание: This monograph reviews and summarizes the substantial body of work that has been published on the transcription by polymerase III over the past 5 years.

Lecture Notes On Emerging Viruses And Human Health: A Guide To Zoonotic Viruses And Their Impact

Автор: Howard Colin R
Название: Lecture Notes On Emerging Viruses And Human Health: A Guide To Zoonotic Viruses And Their Impact
ISBN: 9814366900 ISBN-13(EAN): 9789814366908
Издательство: World Scientific Publishing
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Цена: 84480.00 T
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Описание: Emerging diseases are a major threat to modern societies, impacting individual welfare as well as economic development. This book provides an overview of how best to prepare for disease emergence as it intends to increase awareness of how vulnerable modern society is in preparedness for such events.

Viruses and Human Cancer

Автор: Mei Hwei Chang; Kuan-Teh Jeang
Название: Viruses and Human Cancer
ISBN: 366250829X ISBN-13(EAN): 9783662508299
Издательство: Springer
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Цена: 130430.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Research on oncogenic viruses and related human cancers has advanced rapidly in the past decade. Most articles, however, focus on a specific oncogenic virus and cancer. There is consequently a need for a comprehensive, up-to-date monograph that offers broad and integrated knowledge. Viruses and Human Cancer – From Basic Science to Clinical Prevention is designed to meet this need by providing an advanced overview on the basic and clinical aspects of oncogenic viruses and the human cancers that they cause. Virology, virus-induced inflammation and tissue injuries, oncogenic mechanisms, epidemiology, and current and emerging preventive and therapeutic strategies are all discussed in detail. In addition, the book covers the individual aspects of seven oncogenic viruses, i.e., hepatitis B virus, hepatitis C virus, human papilloma virus, Epstein-Barr virus, human T-cell lymphotropic virus, Kaposi sarcoma-associated herpes virus, and Merkel cell polyomavirus, and the related human cancers.

Structure-Function Relationships of Human Pathogenic Viruses

Автор: Andreas Holzenburg; Elke Bogner
Название: Structure-Function Relationships of Human Pathogenic Viruses
ISBN: 1475782268 ISBN-13(EAN): 9781475782264
Издательство: Springer
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Цена: 167700.00 T
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Описание: Structure-Function Relationships of Human Pathogenic Viruses provides information on the mechanisms by which viruses enter the cell, replicate, package their DNA into capsids and mature into new virions.

Maternal Fetal Transmission of Human Viruses and their Influence on Tumorigenesis

Автор: Gy?rgy Berencsi III
Название: Maternal Fetal Transmission of Human Viruses and their Influence on Tumorigenesis
ISBN: 9401782490 ISBN-13(EAN): 9789401782494
Издательство: Springer
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Цена: 156720.00 T
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Описание: Covering a host of topics related to the processes involved in transmitting viral infections between pregnant women and their unborn babies, this volume discusses the links between bidirectional maternal-fetal cell transport and fetal and neonatal tumors.

Structure-Function Relationships of Human Pathogenic Viruses

Автор: Andreas Holzenburg; Elke Bogner
Название: Structure-Function Relationships of Human Pathogenic Viruses
ISBN: 0306467682 ISBN-13(EAN): 9780306467684
Издательство: Springer
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Цена: 204970.00 T
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Описание: Provides information on the mechanisms by which viruses enter the cell, replicate, package their DNA into capsids and mature into new virions. This volume illustrates the fundamental processes involved in viral life cycles using information from research laboratories around the world.

Human oncogenic viruses

Автор: Ou, Jing-hsuing
Название: Human oncogenic viruses
ISBN: 9812833463 ISBN-13(EAN): 9789812833464
Издательство: World Scientific Publishing
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Цена: 121270.00 T
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Описание: Viruses are the causes of approximately 25 per cent of human cancers. This book provides a comprehensive review of the molecular biology of oncogenic viruses and the cancers they cause. It discusses viruses such as hepatitis B virus, hepatitis C virus, human papilloma viruses, Epstein-Barr virus, and human T-cell leukemia virus type 1.

Insight into Influenza Viruses of Animals and Humans

Автор: Sanjay Kapoor; Kuldeep Dhama
Название: Insight into Influenza Viruses of Animals and Humans
ISBN: 3319357611 ISBN-13(EAN): 9783319357614
Издательство: Springer
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Цена: 121110.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides salient information on all aspects of influenza/flu viruses affecting animals and humans. It specifically reviews the properties and replication of influenza viruses; their evolution and emergence; epidemiology; role of migratory birds in disease transmission; clinical signs in humans, animals and poultry; pathogenesis and pathogenicity; public health importance and potential threats; diagnosis; prevention and control measures; and pandemic preparedness. Influenza/flu viruses evolve continuously and jump species causing epidemics as well as pandemics in both human and animals. During the past 150 years, various strains of influenza virus like the Spanish flu, Asian flu, Hong Kong flu, bird flu and swine flu were responsible for high mortality in humans as well as birds. High mutation rates, antigenic shifts, drifts, reassortment phenomena, and the development of antiviral drug resistance all contribute to ineffective chemotherapy and vaccines against influenza viruses. Due to their devastating nature, high zoonotic implications and high mortality in humans and poultry, they have a severe impact on the socioeconomic status of countries. Disease awareness, rapid and accurate diagnosis, surveillance, strict biosecurity, timely adoption of appropriate preventive and control measures and pandemic preparedness are crucial to help reduce virus transmission, thus reducing clinical cases, deaths and pandemic threats.


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