Lung Cancer, Part I, An Issue Of Clinics In Chest Medicine,41-1, Rivera, M. Patricia
Автор: O`donnell, Denis Neder, Alberto Название: Exercise physiology, an issue of clinics in chest medicine ISBN: 0323678378 ISBN-13(EAN): 9780323678377 Издательство: Elsevier Science Рейтинг: Цена: 107090.00 T Наличие на складе: Невозможна поставка. Описание: This issue of Clinics in Chest Medicine, edited by Dr. Denis O'Donnell and Dr. Alberto Neder, focuses on Clinical Respiratory Physiology. Articles include: The Pathophysiology of Obstructive Sleep Apnea; The Physiology of Mechanical Ventilation; Exercise Pathophysiology in Congestive Heart Failure; Control of Breathing; Breathing at Extremes; Exercise Pathophysiology in Interstitial Lung Disease; Importance of Physiology in Clinical Decision-Making in the ICU; Pulmonary Hypertension and Exercise; Physiologic Effects of Oxygen Supplementation During Exercise in COPD; Benefits and Pitfalls of DLCO measurements in Clinical Practice; Cardio-pulmonary Interactions in COPD-CHF; Exercise Physiology in COPD; Dyspnea of Unknown Origin: The Role of Exercise Testing; Assessment of Ventilatory Limitation During Exercise; Respiratory Muscle Assessment in Clinical Practice; Exertional Periodic Breathing in Heart Failure; and Strategies to Increase Physical Activity in Chronic Respiratory Diseases.
Название: Tuberculosis, An Issue Of Clinics In Chest Medicine,40-4 ISBN: 0323682154 ISBN-13(EAN): 9780323682152 Издательство: Elsevier Science Рейтинг: Цена: 107090.00 T Наличие на складе: Нет в наличии. Описание: Barry Eichengreen presents a new analysis of the Depression by exploring the link between global economic crisis and the the gold standard (the framework for international monetary affairs until 1931). The events described had a profound effect upon twentieth-century history: the Depression abetted the rise of Hitler and the demise of the gold standard is a historical cause of inflation.
Автор: Lee-Chiong, Teofilo Название: Essentials Of Sleep Medicine For The Primary Care Provider, An Issue Of Sleep Medicine Clinics,15-2 ISBN: 0323777066 ISBN-13(EAN): 9780323777063 Издательство: Elsevier Science Рейтинг: Цена: 56970.00 T Наличие на складе: Нет в наличии. Описание: This issue of Sleep Medicine Clinics has been compiled by esteemed Consulting Editor, Teofilo Lee-Chiong, and brings together recent sleep medicine articles that will be useful for Primary Care Providers. Topics include: Internet-Delivered Cognitive Behavioral Therapy for Insomnia Tailoring Cognitive Behavioral Therapy for Insomnia for Patients with Chronic Insomnia; Prescription Drugs Used in Insomnia; Hypnotic Discontinuation in Chronic Insomnia; Evaluation of the Sleepy Patient Differential Diagnosis; Subjective and Objective Assessment of Hypersomnolence; Pharmacologic Management of Excessive Daytime Sleepiness; Nonpharmacologic Management of Excessive Daytime Sleepiness; Treatment of Obstructive Sleep Apnea Choosing the Best Positive Airway Pressure Device; Treatment of Obstructive Sleep Apnea Choosing the Best Interface; Treatment of Obstructive Sleep Apnea Achieving Adherence to Positive Airway Pressure Treatment and Dealing with Complications; Oral Appliances in the Management of Obstructive Sleep Apnea; Avoiding and Managing Oral Appliance Therapy Side Effects; Positional Therapy for Positional Obstructive Sleep Apnea; Pharmacologic and Nonpharmacologic Treatment of Restless Legs Syndrome; Drugs Used in Parasomnia; Drugs Used in Circadian Sleep-Wake Rhythm Disturbances; Sleep in the Aging Population; and Sleep, Health, and Society.
Автор: Diego Marquez Medina Название: Fighting Lung Cancer Through the HER Family of Surface Receptors ISBN: 1633210928 ISBN-13(EAN): 9781633210929 Издательство: Nova Science Рейтинг: Цена: 211190.00 T Наличие на складе: Невозможна поставка. Описание: Lung cancer is the most common and most lethal malignancy world-wide, causing 1.4 million diseases every year. Half of non-small cell lung cancers (NSCLC) are diagnosed at such an advanced stage that a cure cannot be considered a realistic aim, and over 75% of cases selected for a curative treatment eventually relapse within five years. The 5-year overall survival rates are less than 20% for NSCLC patients. As a disease, NSCLC demands our maximum abilities as researchers, physicians, and care-givers, and a continuous updating of our knowledge. Conventional chemotherapy for advanced NSCLC does not provide a great long-term benefit in terms of survival. Accordingly, a different therapeutic approach has to be explored. The human epidermal growth factor family of surface receptors (HER) became a critical target to be investigated. The epidermal growth factor receptor (EGFR) is over-expressed in over 80% of non-small cell lung cancer. The presence of sensitising conformational mutations in the EGFR increases the efficacy of modern tyrosine kinase inhibitors against its inner portion (EGFR-TKI). The EGFR-TKIs greatly prolong disease-free survival of those patients harbouring sensitising EGFR mutations, and have been suggested as an essential tool in the therapeutic repertoire. This volume aims to serve as an updated compendium of biology and applications of anti-EGFR therapies, and offers a look at the future of anti-HER therapy in lung cancer. This volume exhaustively reviews and discusses: 1) the nature and significance of activating EGFR mutations, and those clinical and pathological phenomena related to HER alterations; 2) the most common laboratory methodologies to study EGFR, and the future of HER analysis; 3) the right time to analyse EGFR mutations and evolutionary changes in the HER; 4) EGFR-TKI application in unselected and selected NSCLC patients; 5) upcoming anti-HER therapies; 6) the eventual role of anti-HER therapies in early NSCLC; 7) mechanisms of acquired resistance to anti-HER therapies, and experimental and conventional strategies to bypass them; 8) the application of anti-HER therapies in other malignancies. This book is an indispensable handbook for all those specialists devoted to the diagnosis and management of lung cancer.
Автор: Athanassios Argiris Название: Lung Cancer ISBN: 1936287528 ISBN-13(EAN): 9781936287529 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 130290.00 T Наличие на складе: Невозможна поставка. Описание: Collects over 90 of the most memorable and challenging movement disorder cases from the world`s leading authorities in this specialty. Compelling vignettes covering the entire phenomenology of movement disorders are presented succinctly but descriptively to walk the reader through the diagnostic process-much like being in the examining room with a master clinician.
Автор: Aamir Ahmad; Shirish Gadgeel Название: Lung Cancer and Personalized Medicine ISBN: 3319242210 ISBN-13(EAN): 9783319242217 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This, the first of two volumes on personalized medicine in lung cancer, touches on the core issues related to the understanding of lung cancer—statistics and epidemiology of lung cancer—along with the incidence of lung cancer in non-smokers. A major focus of this volume is the state of current therapies against lung cancer—immune, targeted therapies against EGFR TKIs, KRAS, ALK, angiogenesis; the associated challenges, especially resistance mechanisms; and recent progress in targeted drug development based on metal chemistry. Chapters are written by some of the leading experts in the field, who provide a better understanding of lung cancer, the factors that make it lethal, and current research focused on developing personalized treatment plans. With a unique mix of topics, this volume summarizes the current state-of-knowledge on lung cancer and the available therapies.
1 Lung Cancer Genomics in the Era of Accelerated Targeted Drug Development.-2 Emerging Biomarkers in Personalized Therapy of Lung Cancer.-3 Epithelial mesenchymal transition in aggressive lung cancers.-4 The Role of Cancer Stem Cells in Recurrent and Drug-Resistant Lung Cancer.-5 The microenvironment of lung cancer and therapeutic implications.-6 Epigenetics in Personalized Management of Lung Cancers.-7 Next-Generation Sequencing and Applications to the Diagnosis and Treatment of Lung Cancer.-8 Nanomedicine for Treatment of Lung Cancer.-9 Personalized Therapy of Small Cell Lung Cancer.-10 Personalized Radiation Therapy for Lung Cancer.-11 Current Clinical Management in the era of personalized therapy.-11 Personalized Therapy of Non-Small Cell Lung Cancer.
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