Lung Cancer, Part I, An Issue Of Clinics In Chest Medicine,41-1, Rivera, M. Patricia
Автор: Niederman, Michael S. Название: Pneumonia, An Issue of Clinics in Chest Medicine,39-4 ISBN: 0323643205 ISBN-13(EAN): 9780323643207 Издательство: Elsevier Science Рейтинг: Цена: 107090.00 T Наличие на складе: Невозможна поставка. Описание: Ce Guide de Poche se base sur TOGAF(R) Version 9.2 Entreprise Edition et il fait autorite en la matiere car il en reprend des elements de documentation.En introduisant de maniere concise TOGAF(R), sa lecture ne necessite pas d`avoir des connaissances prealables sur l`architecture d`entreprise.Ce livre vous est principalement destine si vous etes un professionnel concerne par l`architecture: architecte d`entreprise, architecte metiers, architecte des systemes d`information, architecte des donnees, architecte systemes, architecte solutions ou dirigeant cherchant une premiere introduction a TOGAF(R).Ce guide de Poche fournit les elements suivants:¢ une presentation generale de TOGAF(R);¢ une introduction a la Methode de Developpement d`Architecture;¢ une introduction aux notions de Cadre de Contenu d`Architecture et de Continuum d`Entreprise;¢ une introduction au Cadre de Capacite d`Architecture, permettant de creer et de mettre en oeuvre une fonction d`architecture au sein d`une entreprise.Avec plus de 30.000 praticiens certifies dans le monde, TOGAF(R) est le cadre d`Architecture d`Entreprise le plus repandu dans les entreprises. Il s`appuie sur une approche iterative de transformation de l`entreprise qui couvre:¢ le cycle de vie complet des architectures produites, de la vision a la maintenance, en s`attachant a livrer aux acteurs concernes la valeur metier et les qualites attendues;¢ et le developpement continu de la capacite a faire de l`Architecture d`Entreprise.TOGAF(R) a pour objectifs d`ameliorer l`agilite et la performance de l`entreprise, de permettre l`innovation et l`emergence de nouveaux business models, de maitriser la transformation de l`entreprise.TOGAF(R) est un standard de The Open Group et il a beneficie de la mise en commun et de la coordination des bonnes pratiques de plusieurs centaines d`entreprises des domaines IT et industriels.
Автор: Erzurum, Serpil Название: Asthma, An Issue of Clinics in Chest Medicine,40-1 ISBN: 032365536X ISBN-13(EAN): 9780323655361 Издательство: Elsevier Science Рейтинг: Цена: 107090.00 T Наличие на складе: Невозможна поставка. Описание: This issue of Clinics in Chest Medicine, edited by Dr. Serpil Erzurum and Dr. Sumita Khatri, ?is devoted to several key areas of interest related to understanding Asthma and its treatments. Topics covered in this issue include: ?Epidemiology of the Asthma Epidemic in the 21st Century; Classification of Asthma; Genetics and Epigenetics of Asthma; Pro-Inflammatory Pathways in the Pathogenesis of Asthma; Dysfunction of Bronchomotor Tone Pathways in Asthmatic Airway Smooth Muscle; Systematic Approach to Asthma of Varying Severity;?Comorbidities and Non-allergic Triggers in Asthma Exacerbations and Severity; Microbiome in Mechanisms of Asthma; Diet and Metabolism in the Evolution of Asthma and Obesity; The Exposome of Asthma; Life Cycle of Childhood Asthma; Asthma over the Adult Lifecourse, considering Gender and Hormonal Influences;?Asthma and Corticosteroid Responses in Childhood and Adult Asthma; Immunomodulators and Biologics; Bronchial Thermoplasty; Population Health Models for Asthma; and The Future of Asthma Care: Personalized Asthma Treatmen
Автор: Spencer, Jamison Название: Dental Sleep Medicine, An Issue of Sleep Medicine Clinics,13-4 ISBN: 0323643345 ISBN-13(EAN): 9780323643344 Издательство: Elsevier Science Рейтинг: Цена: 56970.00 T Наличие на складе: Невозможна поставка. Описание: A two-act play based on the legendary Battle of Talikota in 1565 and the circumstances leading up to it. Central to the narrative is the story of the power-hungry `Aliya` Rama Raya, the successful son-in-law of the Vijayanagar emperor Krishna Deva Raya, his overarching ways, and his twisted attempts at political alliances and administrative strategies.
Автор: Lee-Chiong, Teofilo Название: Essentials Of Sleep Medicine For The Primary Care Provider, An Issue Of Sleep Medicine Clinics,15-2 ISBN: 0323777066 ISBN-13(EAN): 9780323777063 Издательство: Elsevier Science Рейтинг: Цена: 56970.00 T Наличие на складе: Поставка под заказ. Описание: This issue of Sleep Medicine Clinics has been compiled by esteemed Consulting Editor, Teofilo Lee-Chiong, and brings together recent sleep medicine articles that will be useful for Primary Care Providers. Topics include: Internet-Delivered Cognitive Behavioral Therapy for Insomnia Tailoring Cognitive Behavioral Therapy for Insomnia for Patients with Chronic Insomnia; Prescription Drugs Used in Insomnia; Hypnotic Discontinuation in Chronic Insomnia; Evaluation of the Sleepy Patient Differential Diagnosis; Subjective and Objective Assessment of Hypersomnolence; Pharmacologic Management of Excessive Daytime Sleepiness; Nonpharmacologic Management of Excessive Daytime Sleepiness; Treatment of Obstructive Sleep Apnea Choosing the Best Positive Airway Pressure Device; Treatment of Obstructive Sleep Apnea Choosing the Best Interface; Treatment of Obstructive Sleep Apnea Achieving Adherence to Positive Airway Pressure Treatment and Dealing with Complications; Oral Appliances in the Management of Obstructive Sleep Apnea; Avoiding and Managing Oral Appliance Therapy Side Effects; Positional Therapy for Positional Obstructive Sleep Apnea; Pharmacologic and Nonpharmacologic Treatment of Restless Legs Syndrome; Drugs Used in Parasomnia; Drugs Used in Circadian Sleep-Wake Rhythm Disturbances; Sleep in the Aging Population; and Sleep, Health, and Society.
Автор: Athanassios Argiris Название: Lung Cancer ISBN: 1936287528 ISBN-13(EAN): 9781936287529 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 130290.00 T Наличие на складе: Невозможна поставка. Описание: Collects over 90 of the most memorable and challenging movement disorder cases from the world`s leading authorities in this specialty. Compelling vignettes covering the entire phenomenology of movement disorders are presented succinctly but descriptively to walk the reader through the diagnostic process-much like being in the examining room with a master clinician.
Автор: Aamir Ahmad; Shirish Gadgeel Название: Lung Cancer and Personalized Medicine ISBN: 3319242210 ISBN-13(EAN): 9783319242217 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This, the first of two volumes on personalized medicine in lung cancer, touches on the core issues related to the understanding of lung cancer—statistics and epidemiology of lung cancer—along with the incidence of lung cancer in non-smokers. A major focus of this volume is the state of current therapies against lung cancer—immune, targeted therapies against EGFR TKIs, KRAS, ALK, angiogenesis; the associated challenges, especially resistance mechanisms; and recent progress in targeted drug development based on metal chemistry. Chapters are written by some of the leading experts in the field, who provide a better understanding of lung cancer, the factors that make it lethal, and current research focused on developing personalized treatment plans. With a unique mix of topics, this volume summarizes the current state-of-knowledge on lung cancer and the available therapies.
1 Lung Cancer Genomics in the Era of Accelerated Targeted Drug Development.-2 Emerging Biomarkers in Personalized Therapy of Lung Cancer.-3 Epithelial mesenchymal transition in aggressive lung cancers.-4 The Role of Cancer Stem Cells in Recurrent and Drug-Resistant Lung Cancer.-5 The microenvironment of lung cancer and therapeutic implications.-6 Epigenetics in Personalized Management of Lung Cancers.-7 Next-Generation Sequencing and Applications to the Diagnosis and Treatment of Lung Cancer.-8 Nanomedicine for Treatment of Lung Cancer.-9 Personalized Therapy of Small Cell Lung Cancer.-10 Personalized Radiation Therapy for Lung Cancer.-11 Current Clinical Management in the era of personalized therapy.-11 Personalized Therapy of Non-Small Cell Lung Cancer.
Автор: O`donnell, Denis Neder, Alberto Название: Exercise physiology, an issue of clinics in chest medicine ISBN: 0323678378 ISBN-13(EAN): 9780323678377 Издательство: Elsevier Science Рейтинг: Цена: 107090.00 T Наличие на складе: Поставка под заказ. Описание: This issue of Clinics in Chest Medicine, edited by Dr. Denis O'Donnell and Dr. Alberto Neder, focuses on Clinical Respiratory Physiology. Articles include: The Pathophysiology of Obstructive Sleep Apnea; The Physiology of Mechanical Ventilation; Exercise Pathophysiology in Congestive Heart Failure; Control of Breathing; Breathing at Extremes; Exercise Pathophysiology in Interstitial Lung Disease; Importance of Physiology in Clinical Decision-Making in the ICU; Pulmonary Hypertension and Exercise; Physiologic Effects of Oxygen Supplementation During Exercise in COPD; Benefits and Pitfalls of DLCO measurements in Clinical Practice; Cardio-pulmonary Interactions in COPD-CHF; Exercise Physiology in COPD; Dyspnea of Unknown Origin: The Role of Exercise Testing; Assessment of Ventilatory Limitation During Exercise; Respiratory Muscle Assessment in Clinical Practice; Exertional Periodic Breathing in Heart Failure; and Strategies to Increase Physical Activity in Chronic Respiratory Diseases.
Автор: Diego Marquez Medina Название: Fighting Lung Cancer Through the HER Family of Surface Receptors ISBN: 1633210928 ISBN-13(EAN): 9781633210929 Издательство: Nova Science Рейтинг: Цена: 211190.00 T Наличие на складе: Невозможна поставка. Описание: Lung cancer is the most common and most lethal malignancy world-wide, causing 1.4 million diseases every year. Half of non-small cell lung cancers (NSCLC) are diagnosed at such an advanced stage that a cure cannot be considered a realistic aim, and over 75% of cases selected for a curative treatment eventually relapse within five years. The 5-year overall survival rates are less than 20% for NSCLC patients. As a disease, NSCLC demands our maximum abilities as researchers, physicians, and care-givers, and a continuous updating of our knowledge. Conventional chemotherapy for advanced NSCLC does not provide a great long-term benefit in terms of survival. Accordingly, a different therapeutic approach has to be explored. The human epidermal growth factor family of surface receptors (HER) became a critical target to be investigated. The epidermal growth factor receptor (EGFR) is over-expressed in over 80% of non-small cell lung cancer. The presence of sensitising conformational mutations in the EGFR increases the efficacy of modern tyrosine kinase inhibitors against its inner portion (EGFR-TKI). The EGFR-TKIs greatly prolong disease-free survival of those patients harbouring sensitising EGFR mutations, and have been suggested as an essential tool in the therapeutic repertoire. This volume aims to serve as an updated compendium of biology and applications of anti-EGFR therapies, and offers a look at the future of anti-HER therapy in lung cancer. This volume exhaustively reviews and discusses: 1) the nature and significance of activating EGFR mutations, and those clinical and pathological phenomena related to HER alterations; 2) the most common laboratory methodologies to study EGFR, and the future of HER analysis; 3) the right time to analyse EGFR mutations and evolutionary changes in the HER; 4) EGFR-TKI application in unselected and selected NSCLC patients; 5) upcoming anti-HER therapies; 6) the eventual role of anti-HER therapies in early NSCLC; 7) mechanisms of acquired resistance to anti-HER therapies, and experimental and conventional strategies to bypass them; 8) the application of anti-HER therapies in other malignancies. This book is an indispensable handbook for all those specialists devoted to the diagnosis and management of lung cancer.
Название: Tuberculosis, An Issue Of Clinics In Chest Medicine,40-4 ISBN: 0323682154 ISBN-13(EAN): 9780323682152 Издательство: Elsevier Science Рейтинг: Цена: 107090.00 T Наличие на складе: Поставка под заказ. Описание: Barry Eichengreen presents a new analysis of the Depression by exploring the link between global economic crisis and the the gold standard (the framework for international monetary affairs until 1931). The events described had a profound effect upon twentieth-century history: the Depression abetted the rise of Hitler and the demise of the gold standard is a historical cause of inflation.
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