Lung Cancer and Personalized Medicine: Novel Therapies and Clinical Management, Aamir Ahmad; Shirish M. Gadgeel
Автор: Tan, Dongfeng Название: Principles of Molecular Diagnostics and Personalized Cancer Medicine ISBN: 1451131976 ISBN-13(EAN): 9781451131970 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 250530.00 T Наличие на складе: Поставка под заказ. Описание: Principles of Molecular Diagnostics and Personalized Cancer Medicine" The role of molecular genetics in the treatment of malignancy continues to grow at an astonishing rate. Today’s subspecialized multidisciplinary approach to oncology has incorporated advances in targeted molecular therapy, prognosis, risk assessment, and prevention—all based at least in part on molecular diagnostics and imaging. Inside this cutting-edge resource, readers will explore broad, comprehensive perspectives on the current trends in molecular diagnosis of cancer and personalized cancer medicine. Authoritative discussions share insights from noted experts in cancer research, clinical trials, molecular diagnostics, personalized therapy, bioinformatics, and federal regulations. From the basic mechanisms of carcinogenesis to the most advanced molecular screening, staging, and treatment technologies, readers will discover clear and straightforward discussions directly relevant to patient diagnosis and care. Improve your understanding of… • The basic mechanisms of carcinogenesis— including material on cell proliferation, signal transduction pathways, cancer stem cells, and the interaction between genetics and environmental factors. • The most current molecular techniques —including polymerase chain reaction (PCR) technique, single nucleotide polymorphisms, cancer cytogenomics and epigenetics, whole-genome assessments, and next- generation sequencing. • Molecular tests —including molecular screening, minimal residual disease detection, circulating tumor cell tests, molecular tumor staging, and molecular cancer prognosis assessment. • Imaging and screening technologies —including molecular imaging, genetic tests, biostatistics, and bioinformatics. • The molecular basis of therapy —including critical molecules as special treatment targets, particularly genes/DNA, RNA, micro RNAs, proteins/antibodies, and nanoparticles. • Molecular diagnostics – including updated molecular diagnostic approaches to common malignancies and role of pathology in targeted cancer management. • Targeted treatment – including personalized medicine and targeted therapy for commonly occurring malignancies— plus insights on new approaches to targeted drug discovery and the future of molecular oncology!
Название: Cancer Genetics and Genomics for Personalized Medicine ISBN: 9814669873 ISBN-13(EAN): 9789814669870 Издательство: Taylor&Francis Рейтинг: Цена: 110250.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This book covers almost all fields of cancer genetics and genomics for personalized medicine. Targeted therapy, or precision medicine, or personalized medicine is becoming a standard treatment for many diseases, including cancer. However, how much do we know about the personalized medicine approach? This lucid book helps undergraduate and graduate students, professional researchers, and clinicians to better understand the key concept of personalized medicine.
The most up-to-date topics on personalized medicine in this book cover the recent trends in and updates on lung, gastric, liver, breast, and other types of cancers. Circulating tumor cell, cell-free circulating DNA, and microRNAs are discussed as new diagnostic and prognostic markers for cancer. The avatar mouse model is also discussed for maximizing treatment efficacy and prognosis prediction, and so is microenvironment as a drug resistance mechanism. With classical and new pathological approaches, the book provides a systemic overview of personalized immunotherapies and hyperthermic intraperitoneal chemotherapy, followed by new emerging fields of hereditary cancer, thereby equipping readers to eventually contribute in developing more advanced tools and therapies for curing cancer.
Автор: D. Hunter Best; Jeffrey J. Swensen Название: Molecular Genetics and Personalized Medicine ISBN: 1627039236 ISBN-13(EAN): 9781627039239 Издательство: Springer Рейтинг: Цена: 186340.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book reviews developments in molecular genetics, showing how they have been adopted in clinical practice. The authors simplify complex genetic concepts and focus on patient related issues. The aim is to help shorten the time from lab bench to bedside.
Автор: Hong Hai Et Al Название: Cancer Management With Chinese Medicine ISBN: 9814374741 ISBN-13(EAN): 9789814374743 Издательство: World Scientific Publishing Рейтинг: Цена: 50690.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Documents significant advances made by Western medicine in the treatment of cancer. This book explains the basic principles of Chinese medicine, and the role it plays as complementary treatment for cancer patients undergoing Western treatments comprising surgery, chemotherapy, or radiotherapy, or a combination of these.
Автор: Piccart Название: Breast Cancer Management and Molecular Medicine ISBN: 3540282653 ISBN-13(EAN): 9783540282655 Издательство: Springer Рейтинг: Цена: 326090.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Provides an overview of the techniques, agents and approaches for breast cancer and its treatment. This book presents organ-specific approaches and their impact on the re-classification of breast cancer. It also addresses the integration of biological markers, technologies, diagnostic and therapeutic approaches into clinical trials and practice.
Автор: Aamir Ahmad; Shirish Gadgeel Название: Lung Cancer and Personalized Medicine ISBN: 3319242210 ISBN-13(EAN): 9783319242217 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This, the first of two volumes on personalized medicine in lung cancer, touches on the core issues related to the understanding of lung cancer—statistics and epidemiology of lung cancer—along with the incidence of lung cancer in non-smokers. A major focus of this volume is the state of current therapies against lung cancer—immune, targeted therapies against EGFR TKIs, KRAS, ALK, angiogenesis; the associated challenges, especially resistance mechanisms; and recent progress in targeted drug development based on metal chemistry. Chapters are written by some of the leading experts in the field, who provide a better understanding of lung cancer, the factors that make it lethal, and current research focused on developing personalized treatment plans. With a unique mix of topics, this volume summarizes the current state-of-knowledge on lung cancer and the available therapies.
Название: Towards Personalized Medicine for Cancer ISBN: 1573318159 ISBN-13(EAN): 9781573318150 Издательство: Wiley Рейтинг: Цена: 35640.00 T Наличие на складе: Поставка под заказ. Описание: This volume explores cancer as an individualized problem and addresses the impact of recent advances in cancer biology, genetics, tumor profiling, and medical technology in the personalization of cancer predisposition, diagnosis, prognosis, treatment, and therapy development.
Автор: Da Yong Lu Название: Personalized Cancer Chemotherapy ISBN: 0081003463 ISBN-13(EAN): 9780081003466 Издательство: Elsevier Science Рейтинг: Цена: 154960.00 T Наличие на складе: Невозможна поставка. Описание:
Personalized Cancer Chemotherapy separately describes and addresses "individualized cancer chemotherapy" (ICC) strategies new and old, to provide readers with new insights into their characteristics and techniques, as well as key debates and future trends in this area. The book devotes chapters to drug sensitivity testing, cancer biomarkers and bioinformatics detection, pharmacogenetics, individualized antimetastatic therapy, drug combinations, assistant chemotherapy, and cost-effectiveness considerations.
A major obstacle to controlling cancer growth and metastases in patients is the inappropriate use of anticancer and antimetastatic drugs. Researchers and clinicians are now beginning to focus on ICC also called "personalized cancer chemotherapy" (PCC), to improve therapeutic quality and outcomes by selecting and prescribing the most appropriate and effective drugs. Using genetic, molecular, and bioinformatics data and modern experimental techniques, known tumor genes can be detected more easily than ever before; the average speed of genetic sequencing has increased 15,000 to 50,000 times since the Human Geonme Project was completed.
This book will help readers understand the pros and cons of each individualized cancer chemotherapy strategy from different angles so as to make good judgments and predictions of drug responses and clinical outcomes.
Explores the central components of cancer treatment
Investigates new developments in cancer treatment
Discusses the many strategies of individualized cancer chemotherapy
Автор: Stevens, Michael C. G.; Caron, Hubert N.; Biondi, Название: Cancer in Children Clinical Management Sixth Edition ISBN: 0199599416 ISBN-13(EAN): 9780199599417 Издательство: Oxford Academ Рейтинг: Цена: 126720.00 T Наличие на складе: Невозможна поставка. Описание: Cancer in Children is an established and highly regarded introduction to paediatric oncology. In a clear and concise way, it covers the aetiology, symptoms, and treatment of cancer in children, the complications that can arise during treatment, and the various outcomes of the illness. This new edition brings together an international group of highly respected editors and contributors to provide evidence-based information on how to investigate and treat the common cancers in childhood. State-of-the-art descriptions of what is basic and essential for management is included; there are new chapters on clinical trials, evidence based practice, the treatment of cancer in less well-resourced countries, stem cell and immunotherapy, other malignant / borderline haematological conditions (myelodysplasia and myeloproliferative disorders), and on imaging. These all reflect important changes in the focus of the speciality in recent years. Aimed at paediatric oncologists, and trainees in on
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