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Novel Therapeutic Advances In Glioblastoma,151, Bryukhovetskiy, Igor


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Автор: Bryukhovetskiy, Igor   (Брюховицкий И.)
Название:  Novel Therapeutic Advances In Glioblastoma,151
Перевод названия: Новые терапевтические достижения при глиобластоме, том 151
ISBN: 9780128211144
Издательство: Elsevier Science
Классификация:



ISBN-10: 0128211148
Обложка/Формат: Hardcover
Страницы: 322
Вес: 0.70 кг.
Дата издания: 01.06.2020
Серия: International review of neurobiology
Язык: English
Размер: 229 x 152 x 22
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание:

Novel Therapeutic Advances in Glioblastoma, Volume 151 in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Blood-brain barrier and pathophysiology of brain tumors, Promising strategies of glioblastoma treatment: personalized genotoxic therapy and stem cell transplantation, Extracellular matrix and biocompatible materials in glioblastoma treatment, Expression of Twist associated to microcirculation patterns of human glioma correlated with progression and survival of the patient, Advanced Multimodal Imaging in Differentiating Glioma Recurrence from Post-radiotherapy Changes, Advanced Multimodal Imaging in Differentiating Glioma Recurrence from Post-radiotherapy Changes, and much more.



Advances in Biology and Treatment of Glioblastoma

Автор: Kumaravel Somasundaram
Название: Advances in Biology and Treatment of Glioblastoma
ISBN: 3319568191 ISBN-13(EAN): 9783319568195
Издательство: Springer
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Цена: 158380.00 T
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Описание: This volume covers the most important areas of glioblastoma - surgical resection, molecular pathology, targeted therapies, cancer stem cells, the role of DNA methylation, targeted sequencing for personalized therapy, animal models and advances in pediatric glioblastoma.

Advances in Biology and Treatment of Glioblastoma

Автор: Somasundaram Kumaravel
Название: Advances in Biology and Treatment of Glioblastoma
ISBN: 3319860100 ISBN-13(EAN): 9783319860107
Издательство: Springer
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Цена: 139750.00 T
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Описание: This volume covers the most important areas of glioblastoma - surgical resection, molecular pathology, targeted therapies, cancer stem cells, the role of DNA methylation, targeted sequencing for personalized therapy, animal models and advances in pediatric glioblastoma.

Glioblastoma

Автор: Dimitris G. Placantonakis
Название: Glioblastoma
ISBN: 1493985361 ISBN-13(EAN): 9781493985364
Издательство: Springer
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Цена: 88500.00 T
Наличие на складе: Поставка под заказ.
Описание: This volume details cutting-edge protocols on the characterization of the genome, epigenome, proteome, metabolome and single-cell transcriptome of tumors and tumor-derived cultures. Chapters focus on subpopulations of cells with stem-like properties, laser capture microdissection, and modeling human glioma with human embryonic stem cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Glioblastoma: Methods and Protocols aims to support researchers seeking new and refined protocols to better decrypt this tumor. 

Jack`s Story: A journey through the nightmare of a glioblastoma multiforme brain tumour

Автор: Fleming Ken
Название: Jack`s Story: A journey through the nightmare of a glioblastoma multiforme brain tumour
ISBN: 0648703215 ISBN-13(EAN): 9780648703211
Издательство: Неизвестно
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Цена: 19560.00 T
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Описание: Jack`s Story shares the life and death of Jack Fleming, as told by his father Ken Fleming, through the nightmare of a glioblastoma multiforme brain tumour.

Experimental Models in Glioblastoma Research

Автор: Felix Mircea Brehar, Mircea R Gorgan
Название: Experimental Models in Glioblastoma Research
ISBN: 1633219240 ISBN-13(EAN): 9781633219243
Издательство: Nova Science
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Цена: 168950.00 T
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Описание: This book covers the basic experimental models in glioblastoma research. It starts with a description in the first two chapters of general clinical, neuroimaging and genetic data about glioblastoma (WHO grade IV glioma), which is the most frequent and the most malignant primary tumour in adults. Despite the complex treatment which includes neurosurgery, radiotherapy and chemotherapy, survival of the patients usually is between 9 and 12 months. Moreover, the surgery is not able to cure the disease due to the specific infiltrative growth pattern of glioblastoma. Therefore, laboratory research is essential in order to find new molecular and cellular therapies for this lethal disease. After shortly reviewing the modern hypothesis regarding the origin of glioblastoma in the third chapter, namely the cancer stem cells hypothesis, the author describes step-by-step in the following chapters (Chapters 4-8) the most important in vitro and in vivo models of research in glioblastoma. Chapter 4 is dedicated to the first and the essential step in any research project on glioblastoma: how to obtain good quality glioblastoma samples, how to prepare the samples and how to store the samples long-term for subsequent research. Open surgery and the image-guided stereotactic technique are also described in this chapter. After obtaining the tumour samples, the next step is to initiate the primary cells cultures. These in vitro techniques (either serum conditioning cell cultures and tumour stem cells cultures) will be discussed in detail in Chapters 5 and 6. Usually the new molecules with antitumor activity are tested in vitro on both primary glioblastoma cells cultures but also on glioblastoma cells lines in order to obtain a better standardised results. The next chapter, Chapter 7 is dedicated to in vivo techniques, which are required for testing the anti-tumoural effect of the new molecules before starting with the clinical trials. The author describes in detail the techniques of stereotactic intracranial inoculation of glioblastoma cells (either glioblastoma cell lines or glioblastoma-derived tumour stem cells) and the main growth patterns of the intracranial glioblastoma xenografts obtained using these techniques. Another technique very useful for exploring in real time the migratory glioblastoma cells is the organotypic brain slice cultures which is described in the last chapter of the book.

Glioblastoma

Автор: Placantonakis
Название: Glioblastoma
ISBN: 1493976583 ISBN-13(EAN): 9781493976584
Издательство: Springer
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Цена: 88500.00 T
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Описание:

1. Whole Genome Sequencing-based Discovery of Structural Variants in Glioblastoma

Kazimierz O. Wrzeszczynski, Vanessa Felice, Minita Shah, Sadia Rahman, Anne-Katrin Emde, Vaidehi Jobanputra, Mayu Frank, and Robert B. Darnell

2. Whole Genome DNA Methylation Analysis of Human Glioblastoma using Illumina BeadArrays

Jonathan Serrano and Matija Snuderl

3. Establishing Primary Human Glioblastoma Adherent Cultures from Operative Specimens

Amit D. Gujar, Diane D. Mao, John B. Finlay, and Albert H. Kim

4. Establishing Primary Human Glioblastoma Tumorsphere Cultures from Operative Specimens

Joshua Frenster and Dimitris Placantonakis

5. Isolation of GBM Stem Cells with Flow Cytometry

Julio Inocencio, Joshua Frenster, and Dimitris Placantonakis

6. Lentiviral Transduction of Primary Human Glioblastoma Cultures

Joshua Frenster, Julio Inocencio, and Dimitris Placantonakis

7. Selective Targeting of CD133-expressing Glioblastoma Stem Cells using Lentiviral Vectors

N. Sumru Bayin and Dimitris G. Placantonakis

8. Intracellular pH Measurements in Glioblastoma Cells using the pH-sensitive Dye BCECF

Nataliya Galifianakis, Dimitris G. Placantonakis, and Mitchell Chesler

9. Induction and Assessment of Hypoxia in Glioblastoma Cells in vitro

Jean-Pierre Gagner, Mirna Lechpammer, and David Zagzag

10. Metabolomic Analysis of Glioma Cells Using Nanoflow Liquid Chromatography-tandem Mass Spectrometry

Jingjing Deng, Guoan Zhang, and Thomas A. Neubert

11. Sample Preparation for Relative Quantitation of Proteins Using Tandem Mass Tags (TMT) and Mass Spectrometry (MS)

Hediye Erdjument-Bromage, Fang-Ke Huang, and Thomas A. Neubert

12. Single-Cell RNA Sequencing of Glioblastoma Cells

Rajeev Sen, Igor Dolgalev, N. Sumru Bayin, Adriana Heguy, Aris Tsirigos, and Dimitris G. Placantonakis

13. Evaluation of Radioresponse and Radiosensitizers in Glioblastoma Organotypic Cultures

N. Sumru Bayin, Lin Ma, Dimitris Placantonakis, and Mary Helen Barcellos-Hoff

14. Orthotopic Patient-derived Glioblastoma Xenografts in Mice

Zhongye Xu, Michael Kader, Rajeev Sen, and Dimitris Placantonakis

15. Bioluminescent In Vivo Imaging of Orthotopic Glioblastoma Xenografts in Mice

Joshua Frenster and Dimitris Placantonakis

16. Evaluation of Vascularity, Blood Perfusion, and Oxygen Tension in Tumor Xenografts with Fluorescent Microscopy

N. Sumru Bayin and Dimitris G. Placantonakis

17. Probing Glioblastoma Tissue Heterogeneity with Laser Capture Microdissection

Jean-Pierre Gagner and David Zagzag

18. Flow Cytometric Identification of Tumor-infiltrating Lymphocytes from Glioblastoma

Karolina Woroniecka, Pakawat Chongsathidkiet, Aladine Elsamadicy, Harrison Farber, Xiuyu Cui, and Peter E. Fecci

19. Modeling Glioma with Human Embryonic Stem Cell-derived Neural Lineages

Aram S. Modrek, Jod Prado, Devin Bready, Joravar Dhaliwal, Danielle Golub, and Dimitris G. Placantonakis


Navigating Glioblastoma: A Caregiver`s Perspective

Автор: Connolly Sally
Название: Navigating Glioblastoma: A Caregiver`s Perspective
ISBN: 1476683190 ISBN-13(EAN): 9781476683195
Издательство: Mare Nostrum (Eurospan)
Рейтинг:
Цена: 20330.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: For Sally Connolly, three years of struggle followed her husband Peter`s surgery for terminal brain cancer at 61. Connolly`s clear-eyed and affecting memoir recounts their wrangling over gender roles, money management, domestic decisions and lifestyle changes. Through their traumatic journey, they find humor and comfort in unexpected places.

New targeting in the reversal of resistant glioblastomas

Название: New targeting in the reversal of resistant glioblastomas
ISBN: 0128225270 ISBN-13(EAN): 9780128225271
Издательство: Elsevier Science
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Цена: 151590.00 T
Наличие на складе: Поставка под заказ.
Описание: Chemical industries, dairy units, oil and gas refineries, petro-chemical complexes and fertilizer manufacturing units are few of those areas which are incomplete without anti-corrosive treatment for concrete surface. Environmental effects, spillage and dust- emission are few of those processes which can corrode concrete. Protection of concrete surface of constructed elements from corrosive attack "arising through very harsh corrosive conditions" from all those (and many more) sources of corrosion becomes a moral duty of a Civil Engineer. This book is an effort in this direction to share the applied knowledge with the budding Engineers so that they are aware of such protective measures to be taken for the situations they are put into which I am sure, you must have found it to be of significant importance. One save of production stoppage with use of knowledge contained in this book would serve the very purpose of bringing it out.

Radiobiology of Glioblastoma

Автор: Luigi Pirtoli; Giovanni Luca Gravina; Antonio Gior
Название: Radiobiology of Glioblastoma
ISBN: 3319803212 ISBN-13(EAN): 9783319803210
Издательство: Springer
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Цена: 93160.00 T
Наличие на складе: Невозможна поставка.
Описание: This text properly considers the most recent and relevant advances in molecular RB of GB, taking into account the related topics of pathobiology, and underscores the most promising translational perspectives from the preclinical to the clinical domain.

Glioblastoma - A guide for patients and loved ones: Your guide to glioblastoma and anaplastic astrocytoma brain tumours

Автор: Burrows Gideon D.
Название: Glioblastoma - A guide for patients and loved ones: Your guide to glioblastoma and anaplastic astrocytoma brain tumours
ISBN: 183826180X ISBN-13(EAN): 9781838261801
Издательство: Неизвестно
Рейтинг:
Цена: 12870.00 T
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Описание: A patient centred guide to one of the most challenging cancers, with facts, statistics and advice for patients and loved ones.

Glioblastoma: State-of-the-Art Clinical Neuroimaging (2 Volume Set)

Автор: Michael Iv, Max Wintermark, Tarik F. Massoud
Название: Glioblastoma: State-of-the-Art Clinical Neuroimaging (2 Volume Set)
ISBN: 1536145882 ISBN-13(EAN): 9781536145885
Издательство: Nova Science
Рейтинг:
Цена: 323130.00 T
Наличие на складе: Невозможна поставка.
Описание: Neuroimaging plays a central role in the initial diagnosis and subsequent monitoring of multimodal therapies offered to patients with glioblastoma the most malignant type of brain cancer. The authors present a comprehensive description of current state-of-the-art clinical neuroimaging for glioblastoma. They cover the basic concepts and most recent applications of clinical structural neuroimaging, as well as the latest innovations and up-and-coming techniques for functional imaging of glioblastoma patients.Few comprehensive books are available in this challenging field of clinical medicine. The co-editors are experienced academic neuroradiologists with an active interest in clinical imaging and research of glioblastoma, all within a vibrant clinical environment at Stanford University where the latest innovations in glioblastoma imaging and treatment are being developed. In compiling this book, the co-editors have called upon many of the worlds best clinical and basic neuroscientists specializing in the management of patients with this malignancy, for their expert input on the latest imaging developments and applicable research into glioblastoma.This book is intended for neuroradiologists, neuro-oncologists, neurosurgeons, radiation therapists, and other physicians and scientists engaged in the study and clinical management of patients with glioblastoma. It should also serve as a unique educational and research resource for students and more experienced practitioners alike within this rapidly evolving field.

Glioblastoma:

Автор: Swapan K. Ray
Название: Glioblastoma:
ISBN: 1489981624 ISBN-13(EAN): 9781489981622
Издательство: Springer
Рейтинг:
Цена: 174130.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Glioblastoma is the most malignant brain tumor that still remains incurable. This book discusses the histopathology and molecular biology of glioblastoma as well as current treatment strategies, many of them groundbreaking.


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