Glioblastoma, Dimitris G. Placantonakis

Автор: Luigi Pirtoli; Giovanni Luca Gravina; Antonio Gior
Название: Radiobiology of Glioblastoma
ISBN: 3319803212 ISBN-13(EAN): 9783319803210
Издательство: Springer
Рейтинг:
Цена: 93160.00 T
Наличие на складе: Невозможна поставка.
Описание: This text properly considers the most recent and relevant advances in molecular RB of GB, taking into account the related topics of pathobiology, and underscores the most promising translational perspectives from the preclinical to the clinical domain.

Автор: Kumaravel Somasundaram
Название: Advances in Biology and Treatment of Glioblastoma
ISBN: 3319568191 ISBN-13(EAN): 9783319568195
Издательство: Springer
Рейтинг:
Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume covers the most important areas of glioblastoma - surgical resection, molecular pathology, targeted therapies, cancer stem cells, the role of DNA methylation, targeted sequencing for personalized therapy, animal models and advances in pediatric glioblastoma.

Автор: Fleming Ken
Название: Jack`s Story: A journey through the nightmare of a glioblastoma multiforme brain tumour
ISBN: 0648703215 ISBN-13(EAN): 9780648703211
Издательство: Неизвестно
Рейтинг:
Цена: 19560.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Jack`s Story shares the life and death of Jack Fleming, as told by his father Ken Fleming, through the nightmare of a glioblastoma multiforme brain tumour.

Автор: Felix Mircea Brehar, Mircea R Gorgan
Название: Experimental Models in Glioblastoma Research
ISBN: 1633219240 ISBN-13(EAN): 9781633219243
Издательство: Nova Science
Рейтинг:
Цена: 168950.00 T
Наличие на складе: Невозможна поставка.
Описание: This book covers the basic experimental models in glioblastoma research. It starts with a description in the first two chapters of general clinical, neuroimaging and genetic data about glioblastoma (WHO grade IV glioma), which is the most frequent and the most malignant primary tumour in adults. Despite the complex treatment which includes neurosurgery, radiotherapy and chemotherapy, survival of the patients usually is between 9 and 12 months. Moreover, the surgery is not able to cure the disease due to the specific infiltrative growth pattern of glioblastoma. Therefore, laboratory research is essential in order to find new molecular and cellular therapies for this lethal disease. After shortly reviewing the modern hypothesis regarding the origin of glioblastoma in the third chapter, namely the cancer stem cells hypothesis, the author describes step-by-step in the following chapters (Chapters 4-8) the most important in vitro and in vivo models of research in glioblastoma. Chapter 4 is dedicated to the first and the essential step in any research project on glioblastoma: how to obtain good quality glioblastoma samples, how to prepare the samples and how to store the samples long-term for subsequent research. Open surgery and the image-guided stereotactic technique are also described in this chapter. After obtaining the tumour samples, the next step is to initiate the primary cells cultures. These in vitro techniques (either serum conditioning cell cultures and tumour stem cells cultures) will be discussed in detail in Chapters 5 and 6. Usually the new molecules with antitumor activity are tested in vitro on both primary glioblastoma cells cultures but also on glioblastoma cells lines in order to obtain a better standardised results. The next chapter, Chapter 7 is dedicated to in vivo techniques, which are required for testing the anti-tumoural effect of the new molecules before starting with the clinical trials. The author describes in detail the techniques of stereotactic intracranial inoculation of glioblastoma cells (either glioblastoma cell lines or glioblastoma-derived tumour stem cells) and the main growth patterns of the intracranial glioblastoma xenografts obtained using these techniques. Another technique very useful for exploring in real time the migratory glioblastoma cells is the organotypic brain slice cultures which is described in the last chapter of the book.

Автор: Michael Iv, Max Wintermark, Tarik F. Massoud
Название: Glioblastoma: State-of-the-Art Clinical Neuroimaging (2 Volume Set)
ISBN: 1536145882 ISBN-13(EAN): 9781536145885
Издательство: Nova Science
Рейтинг:
Цена: 323130.00 T
Наличие на складе: Невозможна поставка.
Описание: Neuroimaging plays a central role in the initial diagnosis and subsequent monitoring of multimodal therapies offered to patients with glioblastoma the most malignant type of brain cancer. The authors present a comprehensive description of current state-of-the-art clinical neuroimaging for glioblastoma. They cover the basic concepts and most recent applications of clinical structural neuroimaging, as well as the latest innovations and up-and-coming techniques for functional imaging of glioblastoma patients.Few comprehensive books are available in this challenging field of clinical medicine. The co-editors are experienced academic neuroradiologists with an active interest in clinical imaging and research of glioblastoma, all within a vibrant clinical environment at Stanford University where the latest innovations in glioblastoma imaging and treatment are being developed. In compiling this book, the co-editors have called upon many of the worlds best clinical and basic neuroscientists specializing in the management of patients with this malignancy, for their expert input on the latest imaging developments and applicable research into glioblastoma.This book is intended for neuroradiologists, neuro-oncologists, neurosurgeons, radiation therapists, and other physicians and scientists engaged in the study and clinical management of patients with glioblastoma. It should also serve as a unique educational and research resource for students and more experienced practitioners alike within this rapidly evolving field.

Автор: Placantonakis
Название: Glioblastoma
ISBN: 1493976583 ISBN-13(EAN): 9781493976584
Издательство: Springer
Рейтинг:
Цена: 88500.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

1. Whole Genome Sequencing-based Discovery of Structural Variants in Glioblastoma

Автор: Swapan K. Ray
Название: Glioblastoma:
ISBN: 1489981624 ISBN-13(EAN): 9781489981622
Издательство: Springer
Рейтинг:
Цена: 174130.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Glioblastoma is the most malignant brain tumor that still remains incurable. This book discusses the histopathology and molecular biology of glioblastoma as well as current treatment strategies, many of them groundbreaking.