Environmental Metabolomics, Alvarez-Munoz, Diana

Название: Mass spectrometry in metabolomics
ISBN: 1493912577 ISBN-13(EAN): 9781493912575
Издательство: Springer
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Цена: 186330.00 T
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Описание: Metabolomics is a fast growing field in systems biology and offers a powerful and promising approach for a large range of applications. Metabolomics focuses on deriving the concentrations and fluxes of low molecular weight metabolites in bio-fluids, cells or tissue, plants, foods and related samples and this information provides enormous detail on biological systems and their current status. Mass Spectrometry in Metabolomics: Methods and Protocols presents a broad coverage of the major mass spectrometry (MS)-based metabolomics methods and applications. MS is one of most powerful and commonly used analytical methods in metabolomics; because so many different MS systems are used in metabolomics, this volume includes a wide variety such as triple quads, time of flight, Fourier transform ion cyclotron resonance and even simple quadrupole systems. A wide range of studies are described, with samples ranging from blood and urine to tissue and even plants. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Mass Spectrometry in Metabolomics: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies in an effort to further the dynamic field of metabolomics.

Автор: Martin Giera
Название: Clinical Metabolomics
ISBN: 1493975919 ISBN-13(EAN): 9781493975914
Издательство: Springer
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Цена: 102480.00 T
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Описание: This detailed volume presents a comprehensive compendium of clinical metabolomics protocols covering LC-MS, GC-MS, CE-MS, and NMR-based clinical metabolomics as well as bioinformatics and study design considerations. The methodologies explored here form the core of several very promising initiatives evolving around personalized health care and precision medicine, which can be seen as complimentary to the field of clinical chemistry and aid the aforementioned field with novel disease markers and diagnostic patterns. Written for the highly successful Methods in Molecular Biology series, chapters include brief introductions to their topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Автор: B.J. Nikolau; Eve Syrkin Wurtele
Название: Concepts in Plant Metabolomics
ISBN: 9048174082 ISBN-13(EAN): 9789048174089
Издательство: Springer
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Цена: 213360.00 T
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Описание: Like genomics, which defines genes in a genome irrespective of functionality, metabolomics profiles all metabolites in a biological sample irrespective of the chemical and physical properties of these molecules.

Название: Metabolomics
ISBN: 1498725260 ISBN-13(EAN): 9781498725262
Издательство: Taylor&Francis
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Цена: 117390.00 T
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Описание: This book covers Metabolomics, the scientific study of the chemical processes of the metabolic system. It is based on a course taught to masters and postgraduate students of bioinformatics and statistics at the European Bioinformatics Institute at Cambridge.

Автор: Lammerhofer
Название: Metabolomics in Practice: Successful Strategies to Generate and Analyze Metabolic Data
ISBN: 3527330895 ISBN-13(EAN): 9783527330898
Издательство: Wiley
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Цена: 99210.00 T
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Описание: Unlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often-neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation.

Автор: Dominique Rolin
Название: Metabolomics Coming of Age with its Technological Diversity,67
ISBN: 0123979226 ISBN-13(EAN): 9780123979223
Издательство: Elsevier Science
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Цена: 166190.00 T
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Описание: Publishes reviews on a range of topics in plant sciences. This title features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. It features reviews on metabolomics coming of age with its technological diversity.

Автор: Karsten Suhre
Название: Genetics Meets Metabolomics
ISBN: 1489996958 ISBN-13(EAN): 9781489996954
Издательство: Springer
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Цена: 174130.00 T
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Описание: Written by leading researchers, this book explores the intersection of genetics and metabolomics, and points the way to more comprehensive studies of inborn variation of metabolism. All chapters refer to one or more published experimental datasets.

Автор: Daniel Raftery
Название: Mass Spectrometry in Metabolomics
ISBN: 1493953192 ISBN-13(EAN): 9781493953196
Издательство: Springer
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Цена: 121110.00 T
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Описание:

Part I. Historical and Methodology Overview

1. Overview: of Mass Spectrometry Based Metabolomics: Opportunities and Challenges

G. A. Nagana Gowda and Danijel Djukovic

Part II. Global LC-MS Based Metabolic Profiling

2. Global Metabolic Profiling using Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry

Yunpeng Qi, Yunlong Song, Haiwei Gu, Guorong Fan, and Yifeng Chai

3. LC-MS Profiling to Link Metabolic and Phenotypic Diversity in Plant Mapping Populations

Camilla B. Hill, Antony Bacic, and Ute Roessner

4. Mitochondrial Metabolomics Using High-Resolution Fourier-Transform Mass Spectrometry

Young-Mi Go, Karan Uppal, Douglas I. Walker, ViLinh Tran, Lauriane Dury, Frederick H. Strobel, Hйlиne Baubichon-Cortay, Kurt D. Pennell, James R. Roede, and Dean P. Jones

5. Sample Preparation Methods for LC-MS Based Global Aqueous Metabolite Profiling

Antoni Beltran, Sara Samino, and Oscar Yanes

Part III. Global GC-MS and CE-MS Based Metabolic Profiling

6. Methods of Discovery-Based and Targeted Metabolite Analysis by Comprehensive Two-Dimensional Gas Chromatography with Time-of-Flight Mass Spectrometry Detection

Luke C. Marney, Dr. Jamin C. Hoggard, Kristen J. Skogerboe, and Robert E. Synovec

7. Analysis of Mouse Liver Metabolites by GCЧGC-TOF MS

Xue Shi, Xinmin Yin, and Xiang Zhang

8. Metabolite Fingerprinting by Capillary Electrophoresis-Mass Spectrometry

Antonia Garcia, Shama Naz, and Coral Barbas

Part IV. Isotope Labeling Methods

9. Quantitative Metabolomic Profiling using Dansylation Isotope Labeling and Liquid Chromatography Mass Spectrometry

Ruokun Zhou and Liang Li

10. Quantitative Analysis of Amino and Organic Acids by Methyl Chloroformate Derivatization and GC-MS/MS Analysis

Hans Fredrik Nyvold Kvitvang, Kеre A. Kristiansen, Stina K. Lien, and Per Bruheim

11. Stable Isotope Labeled Tracers for Metabolic Pathway Elucidation by GC-MS and FT-MS

Richard M. Higashi, Teresa W-M. Fan, Pawel K. Lorkiewicz, Hunter N.B. Moseley, and Andrew N. Lane

Part V. Targeted Aqueous Metabolite Profiling

12. Multiplexed, Quantitative and Targeted Metabolite Profiling by LC-MS/MRM

Ru Wei, Guodong Li, and Albert B. Seymour

Part VI. Lipid Profiling Methods

13. Multi-Dimensional Mass Spectrometry-Based Shotgun Lipidomics

Miao Wang and Xianlin Han

14. Comprehensive Quantitative Determination of PUFA-Related Bioactive Lipids for Functional Lipidomics using High Resolution Mass Spectrometry

Mojgan Masoodi and Dietrich A. Volmer

15. Ultra-Performance Liquid Chromatography Mass Spectrometry Targeted Profiling of Bile Acids: Application to Serum, Liver Tissue and Cultured Cells of Different Species

Juan Carlos Garcнa-Caсaveras, Marнa Teresa Donato, and Agustнn Lahoz

Part VII. Profiling Volatile Organic Compounds

16. Analysis of Volatile Organic Compounds in Exhaled Breath by Gas Chromatography-Mass Spectrometry combined with Chemometric Analysis

Jan W. Dallinga, Agnieszka Smolinska, and Frederik-Jan van Schooten

17. Headspace SPME-GC-MS Metabolomics Analysis of Urinary Volatile Organic Compounds (VOCs)

Shucha Zhang and Daniel Raftery

Part VIII. Profiling and Imaging using Atmospheric Sampling Methods

Автор: M. Tomita; T. Nishioka
Название: Metabolomics
ISBN: 443199808X ISBN-13(EAN): 9784431998082
Издательство: Springer
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Цена: 113180.00 T
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Описание: Metabolism is the sum of the chemical reactions in cells that produce life-sustaining chemical energy and metabolites. This book covers research on metabolomics, ranging from the development of specialized chemical analytical techniques to the construction of databases and methods for metabolic simulation.

Название: Capillary Electrophoresis-Mass Spectrometry for Metabolomics
ISBN: 178801104X ISBN-13(EAN): 9781788011044
Издательство: Royal Society of Chemistry
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Цена: 223870.00 T
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Описание: In this book, the unique features of CE-MS for metabolomics studies are highlighted and a comprehensive overview of recent technological developments is given at a level suitable for researchers working in metabolomics, bioanalytics and biomarker analysis.