Название: Metabolomics ISBN: 1498725260 ISBN-13(EAN): 9781498725262 Издательство: Taylor&Francis Рейтинг: Цена: 117390.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book covers Metabolomics, the scientific study of the chemical processes of the metabolic system. It is based on a course taught to masters and postgraduate students of bioinformatics and statistics at the European Bioinformatics Institute at Cambridge.
Автор: Lammerhofer Название: Metabolomics in Practice: Successful Strategies to Generate and Analyze Metabolic Data ISBN: 3527330895 ISBN-13(EAN): 9783527330898 Издательство: Wiley Рейтинг: Цена: 99210.00 T Наличие на складе: Поставка под заказ. Описание: Unlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often-neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation.
Автор: Martin Giera Название: Clinical Metabolomics ISBN: 1493985302 ISBN-13(EAN): 9781493985302 Издательство: Springer Рейтинг: Цена: 79190.00 T Наличие на складе: Поставка под заказ. Описание: This detailed volume presents a comprehensive compendium of clinical metabolomics protocols covering LC-MS, GC-MS, CE-MS, and NMR-based clinical metabolomics as well as bioinformatics and study design considerations. The methodologies explored here form the core of several very promising initiatives evolving around personalized health care and precision medicine, which can be seen as complimentary to the field of clinical chemistry and aid the aforementioned field with novel disease markers and diagnostic patterns. Written for the highly successful Methods in Molecular Biology series, chapters include brief introductions to their topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Clinical Metabolomics: Methods and Protocols aims to serve as the basis for successful communication between scientists from several fields, including chemists, biologist, bioinformaticians, and clinicians, ultimately leading to effective study design and completion.
Автор: Karsten Suhre Название: Genetics Meets Metabolomics ISBN: 1489996958 ISBN-13(EAN): 9781489996954 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Written by leading researchers, this book explores the intersection of genetics and metabolomics, and points the way to more comprehensive studies of inborn variation of metabolism. All chapters refer to one or more published experimental datasets.
Автор: Alvarez-Munoz, Diana Название: Environmental Metabolomics ISBN: 0128181966 ISBN-13(EAN): 9780128181966 Издательство: Elsevier Science Рейтинг: Цена: 114530.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Environmental Metabolomics Applications in Field and Laboratory Studies: From the Exposome to the Metabolome presents an overview of the current state of aquatic environments and problems caused by human pressure and daily life. The presence of contaminants in nature and their effects are evaluated, along with recommendations for preservation. This book not only shows readers how to implement techniques, it also guides them through the process. As metabolomics becomes a more routine technique for environmental studies and future perspectives, a guide for validation and globalization of current approaches is needed.
Presents relevant and reliable information on the use of different analytical techniques for establishing the environmental metabolomics of polluted systems
Includes a critical review of each central topic in every chapter, together with a bibliography and future trends
Provides, for the first time, a global opinion and guide for achieving standardized results
Автор: B.J. Nikolau; Eve Syrkin Wurtele Название: Concepts in Plant Metabolomics ISBN: 9048174082 ISBN-13(EAN): 9789048174089 Издательство: Springer Рейтинг: Цена: 213360.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Like genomics, which defines genes in a genome irrespective of functionality, metabolomics profiles all metabolites in a biological sample irrespective of the chemical and physical properties of these molecules.
Автор: Angelo D`Alessandro Название: High-Throughput Metabolomics ISBN: 149399235X ISBN-13(EAN): 9781493992355 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This detailed volume focuses on recent technological, computational, and biostatistical advances in the field of high-throughput metabolomics. Chapters encompass methods, platforms, and analytical strategies for steady state measurements and metabolic flux analysis with stable isotope-labeled tracers, in biological matrices of clinical relevance and model organisms. Mass spectrometry-based or orthogonal methods are discussed, along with computational and statistical methods to address data sparsity in high-throughput metabolomics approaches. As a part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, High-Throughput Metabolomics: Methods and Protocols provides tools that can bring about the next generation of clinical biochemistry in a cost-effective, rigorous fashion, exponentially advancing our capacity to investigate nature while hastening the advent of personalized medicine.
Название: Cancer Metabolomics 2018 ISBN: 3039213458 ISBN-13(EAN): 9783039213450 Издательство: Неизвестно Рейтинг: Цена: 54340.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
The metabolomics approach, defined as the study of all endogenously-produced low-molecular-weight compounds, appeared as a promising strategy to define new cancer biomarkers. Information obtained from metabolomic data can help to highlight disrupted cellular pathways and, consequently, contribute to the development of new-targeted therapies and the optimization of therapeutics. Therefore, metabolomic research may be more clinically translatable than other omics approaches, since metabolites are closely related to the phenotype and the metabolome is sensitive to many factors. Metabolomics seems promising to identify key metabolic pathways characterizing features of pathological and physiological states. Thus, knowing that tumor metabolism markedly differs from the metabolism of normal cells, the use of metabolomics is ideally suited for biomarker research. Some works have already focused on the application of metabolomic approaches to different cancers, namely lung, breast and liver, using urine, exhaled breath and blood. In this Special Issue we contribute to a more complete understanding of cancer disease using metabolomics approaches.
Автор: Babak Arjmand Название: Genomics, Proteomics, and Metabolomics ISBN: 3030277267 ISBN-13(EAN): 9783030277260 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Поставка под заказ. Описание: This book provides thorough coverage of high-throughput OMICs technologies for the monitoring of stem cells and regenerative medicine. Specific topics covered include the genomics, proteomics, and metabolomics aspects of regenerative medicine, metabolic profiling of mesenchymal stem cells, genome profiling of mesenchymal stem cells, OMICs monitoring of stem cell-derived exosomes, stem cell proteomics, lipidomics, OMICs profiling of cancer (stem) cells, and finally ethical considerations of OMICs-based investigations. Chapters are authored by world-renowned scientists who have valuable expertise in the field of OMICs and regenerative medicine. Genomics, Proteomics, and Metabolomics: Stem Cells Monitoring in Regenerative Medicine, part of Springer’s Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers, clinicians, biologists, biochemists, and pharmaceutical experts conducting research in the fields of stem cell biology, molecular aspects of stem cell research, tissue engineering, regenerative medicine, cellular therapy, OMICs, bioinformatics, and ethics.
Автор: M. Tomita; T. Nishioka Название: Metabolomics ISBN: 443199808X ISBN-13(EAN): 9784431998082 Издательство: Springer Рейтинг: Цена: 113180.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Metabolism is the sum of the chemical reactions in cells that produce life-sustaining chemical energy and metabolites. This book covers research on metabolomics, ranging from the development of specialized chemical analytical techniques to the construction of databases and methods for metabolic simulation.
Автор: Ute Roessner; Daniel Anthony Dias Название: Metabolomics Tools for Natural Product Discovery ISBN: 1627035761 ISBN-13(EAN): 9781627035767 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book presents methodologies for natural product isolation, biomarker discovery, dereplication, biological assays, and comprehensive metabolomic platforms available for high-throughput analyses. It features step-by-step, readily reproducible protocols.
Автор: Dominique Rolin Название: Metabolomics Coming of Age with its Technological Diversity,67 ISBN: 0123979226 ISBN-13(EAN): 9780123979223 Издательство: Elsevier Science Рейтинг: Цена: 166190.00 T Наличие на складе: Поставка под заказ. Описание: Publishes reviews on a range of topics in plant sciences. This title features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. It features reviews on metabolomics coming of age with its technological diversity.
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