Автор: Jiro Nagatomi , Eno Essien Ebong (Editors) Название: Mechanobiology Handbook, 2Nd Ed ISBN: 1498779468 ISBN-13(EAN): 9781498779463 Издательство: Taylor&Francis Рейтинг: Цена: 168430.00 T Наличие на складе: Нет в наличии. Описание: This is a substantial revision of a former reference work, now developed as a primary text for emerging courses in mechanobiology/cell mechanics being offered in a growing number of biomedical engineering and chemical engineering departments worldwide. It will also serve as a professional reference book for engineers, scientists and clinicians.
Автор: Maret Wolfgang Название: Metallomics: A Primer Of Integrated Biometal Sciences ISBN: 178326828X ISBN-13(EAN): 9781783268283 Издательство: World Scientific Publishing Рейтинг: Цена: 31680.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Metallomics bridges chemistry and the biological sciences from a global and quantitative systems approach.
Автор: Wallace F. Marshall Название: Introduction to Quantitative Cell Biology ISBN: 1615047700 ISBN-13(EAN): 9781615047703 Издательство: Mare Nostrum (Eurospan) Цена: 41760.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: For the past decade or more, much of cell biology research has been focused on determining the key molecules involved in different cellular processes, an analytical problem that has been amenable to biochemical and genetic approaches. Now, we face an integrative problem of understanding how all of these molecules work together to produce living cells, a challenge that requires using quantitative approaches to model the complex interactions within a cell, and testing those models with careful quantitative measurements.This book is an introductory overview of the various approaches, methods, techniques, and models employed in quantitative cell biology, which are reviewed in greater detail in the other volumes in this e-book series. Particular emphasis is placed on the goals and purpose of quantitative analysis and modeling, and the special challenges that cell biology holds for understanding life at the physical level.
Автор: University of Florida Название: Life in Motion: Unlocking the Secret to Healthy Aging ISBN: 1942852169 ISBN-13(EAN): 9781942852162 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 6650.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The University of Florida has an ambitious goal: to harness the power of its faculty, staff, students, and alumni to solve some of society’s most pressing problems and to become a resource for the state of Florida, the nation, and the world.In the upcoming decades, an unprecedented demographic shift will take place; the eighty-five and over population is projected to climb far higher than any other age group. To keep the current elderly population healthy and help prevent future generations from experiencing poor health outcomes, researchers are studying crucial connections between skeletal muscles and whole-body health.The University of Florida is at the forefront of this research, utilizing its nationally recognized excellence in the fields of muscle biology and exercise physiology to discover unique ways to preserve muscle health in the aging and those with diseases. Find out how the proteins within muscle can be manipulated to reduce recovery times for individuals who are bedridden. Learn how older, elite athletes have resisted the inevitable degeneration that comes with aging, and how intermittent fasting may help you live longer and healthier. Step inside the lab where a researcher is uncovering the origins of cancer cachexia?a wasting syndrome responsible for 20 percent of cancer deaths worldwide?to improve the lives of patients.The loss of skeletal muscle through disease, disuse, or aging is associated with a host of poor health outcomes, but promising new avenues of research are being studied every day at the University of Florida to make for a healthier tomorrow.
Автор: Khawaja Husnain Haider Название: Stem Cells - From Drug to Drug Discovery ISBN: 3110496283 ISBN-13(EAN): 9783110496284 Издательство: Walter de Gruyter Цена: 123910.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Stem cell based therapy is a 21st century approach of therapeutic intervention which epitomizes a shift from conventional symptomatic treatment strategy to addressing the root cause of the disease process. This is especially a hope for the patients suffering from diseases such as Alzheimer, diabetes, myocardial infarction and other diseases which have always been considered as incurable. Moreover, stem cells provide excellent in vitro disease models for drug development. This book is a compilation of the bench experience of experts from various research labs involved in the cutting edge area of research, describing the use of stem cells both as part of the combinatorial therapeutic intervention approach and as tools (disease model) during drug development.
Автор: Goodman, Steven Название: Medical Cell Biology. 3Ed. ISBN: 0123704588 ISBN-13(EAN): 9780123704580 Издательство: Elsevier Science Рейтинг: Цена: 32550.00 T Наличие на складе: Нет в наличии. Описание: Focuses on the scientific aspects of cell biology useful to medical students, dental students, veterinary students, and prehealth undergraduates. This book explains general cell biology principles in the context of organ systems and human and animal disease.
Автор: Goodman Название: Medical Cell Biology ISBN: 039758427X ISBN-13(EAN): 9780397584277 Издательство: Lippincott Williams & Wilkins Цена: 22820.00 T Наличие на складе: Невозможна поставка. Описание: The thoroughly revised, updated Second Edition of Medical Cell Biology is the only textbook that fully meets the content requirement of the cell biology portion of the new U.S./Canadian Curriculum in the Anatomical Sciences. In 352 pages, the book provides all the information a medical student needs to practice modern medicine and perform well on Board exams. All chapters of this edition have been updated to meet current curriculum requirements, and the chapter on cell motility has been completely rewritten. Each chapter opens with a new clinical case prepared by Betty S. Pace, MD, for the Second Edition, and concludes with the diagnosis and a discussion of the disease. National Board Part I type questions appear at the end of each chapter, and answers are given at the end of the book. A computer disk with over 200 Board type questions, answers, and explanations comes with the book. Lecturers - Click here to order a FREE Review Copy of this title !
Автор: Orrenius Название: Mitochondrial Signaling in Health and Disease ISBN: 1439880026 ISBN-13(EAN): 9781439880029 Издательство: Taylor&Francis Рейтинг: Цена: 193950.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.
With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate cell function by discrete signaling pathways. Topics discussed include:
Electron transport and energy production
Mitochondrial biogenesis and dynamics
Mitochondrial signaling
Apoptosis and autophagy
Pharmacology signaling
Epigenetic signaling: mitochondrial methylation and acetylation reactions
An essential resource for life and health scientists as well as pharmaceutical industry professionals, this volume highlights the importance of mitochondrial signaling and its role in establishing a harmonized communication between several cellular compartments. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.
Автор: Aaron S. Goldstein Название: Biomaterials For Cell Delivery ISBN: 1498743161 ISBN-13(EAN): 9781498743167 Издательство: Taylor&Francis Рейтинг: Цена: 178640.00 T Наличие на складе: Нет в наличии. Описание: The purpose of this book is to summarize key strategies and recent accomplishments in the area of developing cell/biomaterial constructs for regenerative medicine. The bulk of the book is devoted to unique problems associated with key tissue and organ targets.
Автор: Shamim I. Ahmad Название: Handbook of Mitochondrial Dysfunction ISBN: 1138336084 ISBN-13(EAN): 9781138336087 Издательство: Taylor&Francis Рейтинг: Цена: 178640.00 T Наличие на складе: Невозможна поставка. Описание: Mitochondria produce the chemical energy necessary for eukaryotic cell functions; hence mitochondria are an essential component of health, playing roles in both disease and aging. More than 80 human diseases and syndromes are associated with mitochondrial dysfunction; this book focuses upon diseases linked to mitochondria.
The fibroblast growth factor (FGF) family of ligands and the corresponding family of FGF receptor tyrosine kinases comprise one of the most versatile and diverse growth factor signaling families in vertebrates, found virtually in every tissue and cell type where they regulate metabolic and physiologic function, maintain tissue homeostasis, and mediate injury response, tissue repair, and regeneration. As a result, FGFs play critical roles in a wide variety of normal biological and abnormalities in FGF signaling can lead to a variety of disease states from developmental malformations, to atherosclerosis, pulmonary hypertension and cancer among many others. A thorough understanding of this system is necessary for critical insights into both normal and disease biology and is essential to development of rationale therapeutic strategies aimed at treatment of FGF-dependent diseases states.
Recent years have seen advances in our understanding of FGFs role in endothelial and, more general, vascular biology, the subject of this book. In particular, FGFs have been implicated in the maintenance of vascular homeostasis and control of blood vessel permeability while aberrant FGF signaling has been shown to be central to the development of pulmonary hypertension, and endothelial-to-mesenchymal transition, a process implicated in the development of atherosclerosis. Finally, FGFs ability to stimulate blood vessel growth has been explored in therapeutic angiogenesis approaches.
With this in mind, the present monograph is structured to provide comprehensive information to a reader interested in FGFs in general and vascular biology in particular. To this end, we explore everything from the structure and signaling of FGFs and their receptors (Chapters 1, 2 and 3) to their role in the regulation of vascular homeostasis (Chapter 4) and cardiovascular diseases (Chapters 5 and 6). We then address new developments in FGF therapeutics (chapter 7) and explore FGF biology in the epithelium (Chapter 8) thereby providing a complete analysis of this growth factor family biology in two closely related but distinctly different environments -- endothelium and epithelium. Finally, we examine FGF biology in eye disease and in cancer.
It is our hope that this comprehensive treatment of FGF vascular biology and its application will provide the reader with the accurate and timely summary of this rapidly moving field.
Автор: Charles Durand, Pierre Charbord Название: Stem Cell Biology and Regenerative Medicine ISBN: 8793237073 ISBN-13(EAN): 9788793237070 Издательство: Taylor&Francis Рейтинг: Цена: 104120.00 T Наличие на складе: Невозможна поставка. Описание: The study of stem cell biology is under intensive investigations. Because stem cells have the unique capability to self-renew and differentiate into one or several cell types, they play a critical role in development, tissue homeostasis and regeneration. Stem cells also constitute promising cell candidates for cell therapy. The aim of this book is to provide an accurate knowledge on stem cell biology and regenerative medicine. This book will cover many topics in the field and is based on seminars given by recognized scientists involved the international master program on stem cell biology at the University Pierre and Marie Curie (UPMC) in Paris. Content Preface. Pierre Charbord and Charles Durand. 1) General concepts 1.Stem cell concepts. Charles Durand and Pierre Charbord. 2.Transcriptional regulation in stem cells. Eric Soler and Frank Grosveld. 3.DNA repair in stem cells. Leyla Vahidi Ferdousi and Miria Ricchetti. 4. Stem cells and epigenetic regulation. Emma L. Walton and Claire Francastel. 5. Hydra and the evolution of stem cells. Alexander Klimovich, Anna Marei B hm and Thomas C.G. Bosch. 6. Ontogeny of stem cells. Thierry Jaffredo. 7. Regeneration in anamniotic vertebrates. Dunja Knapp. 8. Computational models of spatio-temporal stem cell organization. Peter Buske and Joerg Galle. 2) Pluripotent stem cells 9. X chromosome inactivation in stem cells and development. Agnese Loda, Friedemann Loos and Joost Gribnau. 10. Molecular machinery of reprogramming. Romain Desprat, Ollivier Milhavet and Jean-Marc Lemaitre. 11. Modeling human genetic disorders using induced pluripotent stem cells. Franck Lebrin. 3) Adult stem cells 12. Developmental biology of hematopoietic stem cells: Cellular aspects. Laurent Yvernogeau, Jean-Charles Boisset and Catherine Robin. 13. Developmental biology of haematopoietic stem cells: Cell intrinsic and extrinsic regulators of their emergence. Katrin Ottersbach. 14. Biology of hematopoietic stem cells in the adult. Marie-Laure Arcangeli, Rima Haddad, Francoise Pflumio. 15. Epithelial stem cells in the skin. Romain Fontaine, Mathieu Castela and Selim Aractingi. 16. Skeletal muscle stem cells. Elisa Negroni, Maximilien Bencze, St phanie Duguez, Gillian Butler-Browne and Vincent Mouly. 17. Mammary stem cells. Marie-Ange Deugnier, Marisa M. Faraldo and Marina A. Glukhova. 18. Intestinal stem cells. Silvia Fre. 19. Neural stem cells. Nathalie Kubis and Martin Catala. 20. Dental stem cells. Anne Poliard. 21. Bone marrow Mesenchymal Stem Cells: from stemness to stromal property of hematopoietic support. Pierre Charbord and Bruno Delorme. 22. Retinal stem cells. Olivier Goureau, Ang lique Terray, Katherine S. Matho, Sacha Reichman, and Gael Orieux. 4) Stem cell-related diseases and therapy using stem cells 23. Leukemic stem cells: what the concept brings to disease and patient management. Berent Lunden and Christine Chomienne. 24. Stem cells for cardiac repair. Philippe Menasch . 25. Stem cells for red blood cell production. Christelle Mazurier, Guillaume F Rousseau, Luc Douay and H l ne Lapillonne. 26. Prospectives for therapy with stem cells in skeletal muscular diseases. Maximilien Bencze, Elisa Negroni, Vincent Mouly and Gillian Butler-Browne. 5) Regulatory and philosophical aspects 27. Legal framework for research on Human Embryonic Stem Cells in France and in Europe. Arnaud de Guerra, Emmanuelle Prada-Bordenave 28. Stem cell epistemological issues. Lucie Laplane. 29. Future outlook. Pierre Charbord and Charles Durand.
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