Advancing Healthcare Through Personalized Medicine, Hays, Priya
Автор: Snyder Michael Название: Genomics and Personalized Medicine: What Everyone Needs to Know(r) ISBN: 0190234768 ISBN-13(EAN): 9780190234768 Издательство: Oxford Academ Рейтинг: Цена: 11610.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In 2001 the Human Genome Project succeeded in mapping the DNA of humans. This landmark accomplishment launched the field of genomics, the integrated study of all the genes in the human body and the related biomedical interventions that can be tailored to benefit a person's health. Today genomics, part of a larger movement toward personalized medicine, is poised to revolutionize health care. By cross-referencing an individual's genetic sequence -- their genome -- against known elements of "Big Data," elements of genomics are already being incorporated on a widespread basis, including prenatal disease screening and targeted cancer treatments. With more innovations soon to arrive at the bedside, the promise of the genomics revolution is limitless. This entry in the What Everyone Needs to Know series offers an authoritative resource on the prospects and realities of genomics and personalized medicine. As this science continues to alter traditional medical paradigms, consumers are faced with additional options and more complicated decisions regarding their health care. This book provides the essential information everyone needs.
Автор: Hays Название: Advancing Healthcare Through Person ISBN: 1498767087 ISBN-13(EAN): 9781498767088 Издательство: Taylor&Francis Рейтинг: Цена: 51030.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This innovative book provides a unique perspective on the biomedical and societal implications of personalized medicine and how it will help mitigate the healthcare crisis and rein in ever-growing expenditure. It introduces the reader to underlying concepts at the heart of personalized medicine - pharmacogenomics, targeted therapies and individualized diagnosis and treatment - and shows how, with the advent of genomic technologies, clinicians will have the capability to predict and diagnose disease more efficiently. Advocating a patient-centred approach at the heart of care, this introduction to personalized medicine, the science behind it, its economic effects, its effects upon patients and its overall implications for society will be invaluable to clinicians, to healthcare providers and to patients.
Автор: Kevin M. Koo Название: Advancing Gene Fusion Detection Towards Personalized Cancer Nanodiagnostics ISBN: 3030309991 ISBN-13(EAN): 9783030309992 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book presents a unique concept of merging nanotechnology and novel urinary biomarkers for accurate early prostate cancer detection, discussing an entire progressive pipeline of innovative new strategies in biosensor development, from a simple colorimetric system to a complex system for simultaneous multiple biomarker sensing. For newcomers to the field of nucleic acid biosensing, it also describes various isothermal amplification and amplification-free strategies, which are currently the main research areas. Lastly, the book introduces and demonstrates the notion of clinical nanobiosensor validation toward clinical translation: the ultimate aim of researchers in the biosensor field. This book is a valuable reference resource learners seeking inspiration for cancer biosensor development.
Название: Cancer Genetics and Genomics for Personalized Medicine ISBN: 9814669873 ISBN-13(EAN): 9789814669870 Издательство: Taylor&Francis Рейтинг: Цена: 110250.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This book covers almost all fields of cancer genetics and genomics for personalized medicine. Targeted therapy, or precision medicine, or personalized medicine is becoming a standard treatment for many diseases, including cancer. However, how much do we know about the personalized medicine approach? This lucid book helps undergraduate and graduate students, professional researchers, and clinicians to better understand the key concept of personalized medicine.
The most up-to-date topics on personalized medicine in this book cover the recent trends in and updates on lung, gastric, liver, breast, and other types of cancers. Circulating tumor cell, cell-free circulating DNA, and microRNAs are discussed as new diagnostic and prognostic markers for cancer. The avatar mouse model is also discussed for maximizing treatment efficacy and prognosis prediction, and so is microenvironment as a drug resistance mechanism. With classical and new pathological approaches, the book provides a systemic overview of personalized immunotherapies and hyperthermic intraperitoneal chemotherapy, followed by new emerging fields of hereditary cancer, thereby equipping readers to eventually contribute in developing more advanced tools and therapies for curing cancer.
Автор: Snyder, Michael Название: Genomics and Personalized Medicine ISBN: 0190234776 ISBN-13(EAN): 9780190234775 Издательство: Oxford Academ Рейтинг: Цена: 50680.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Today genomics, part of a larger movement toward personalized medicine, is poised to revolutionize health care. By cross-referencing an individual`s genetic sequence - their genome - against known elements of "Big Data," elements of genomics are already being incorporated on a widespread basis, including prenatal disease screening and targeted cancer treatments. With more innovations soon to arrive at the bedside, the promise of the genomics revolution islimitless.
Автор: Geoffrey S. Ginsburg Название: Genomic and Personalized Medicine ISBN: 0128006811 ISBN-13(EAN): 9780128006818 Издательство: Elsevier Science Рейтинг: Цена: 101050.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Genomic and Precision Medicine: Foundations, Translation, and Implementation highlights the various points along the continuum from health to disease where genomic information is impacting clinical decision-making and leading to more personalization of health care.
The book pinpoints the challenges, barriers, and solutions that have been, or are being, brought forward to enable translation of genome based technologies into health care. A variety of infrastructure (data systems and EMRs), policy (regulatory, reimbursement, privacy), and research (comparative effectiveness research, learning health system approaches) strategies are also discussed. Readers will find this volume to be an invaluable resource for the translational genomics and implementation science that is required to fully realize personalized health care.
Provides a comprehensive volume on the translation and implementation of biology into health care provision
Presents succinct commentary and key learning points that will assist readers with their local needs for translation and implementation
Includes an up-to-date overview on major 'translational events' in genomic and personalized medicine, along with lessons learned
Автор: Tan, Dongfeng Название: Principles of Molecular Diagnostics and Personalized Cancer Medicine ISBN: 1451131976 ISBN-13(EAN): 9781451131970 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 250530.00 T Наличие на складе: Поставка под заказ. Описание: Principles of Molecular Diagnostics and Personalized Cancer Medicine" The role of molecular genetics in the treatment of malignancy continues to grow at an astonishing rate. Today’s subspecialized multidisciplinary approach to oncology has incorporated advances in targeted molecular therapy, prognosis, risk assessment, and prevention—all based at least in part on molecular diagnostics and imaging. Inside this cutting-edge resource, readers will explore broad, comprehensive perspectives on the current trends in molecular diagnosis of cancer and personalized cancer medicine. Authoritative discussions share insights from noted experts in cancer research, clinical trials, molecular diagnostics, personalized therapy, bioinformatics, and federal regulations. From the basic mechanisms of carcinogenesis to the most advanced molecular screening, staging, and treatment technologies, readers will discover clear and straightforward discussions directly relevant to patient diagnosis and care. Improve your understanding of… • The basic mechanisms of carcinogenesis— including material on cell proliferation, signal transduction pathways, cancer stem cells, and the interaction between genetics and environmental factors. • The most current molecular techniques —including polymerase chain reaction (PCR) technique, single nucleotide polymorphisms, cancer cytogenomics and epigenetics, whole-genome assessments, and next- generation sequencing. • Molecular tests —including molecular screening, minimal residual disease detection, circulating tumor cell tests, molecular tumor staging, and molecular cancer prognosis assessment. • Imaging and screening technologies —including molecular imaging, genetic tests, biostatistics, and bioinformatics. • The molecular basis of therapy —including critical molecules as special treatment targets, particularly genes/DNA, RNA, micro RNAs, proteins/antibodies, and nanoparticles. • Molecular diagnostics – including updated molecular diagnostic approaches to common malignancies and role of pathology in targeted cancer management. • Targeted treatment – including personalized medicine and targeted therapy for commonly occurring malignancies— plus insights on new approaches to targeted drug discovery and the future of molecular oncology!
Автор: Sweet, Kevin M., Michaelis, Ron C Название: The busy physician`s guide to genetics, genomics and personalized medicine ISBN: 9400711468 ISBN-13(EAN): 9789400711464 Издательство: Springer Рейтинг: Цена: 174150.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In the coming decade, the focus of medicine will shift from a disease-oriented approach, where the physician prescribes according to the disease the patient has, to a personalized approach, in which the physician first considers the patient’s individual biochemistry before prescribing a treatment. Personalized medicine has the potential to improve efficacy and safety in virtually all fields of medicine. Unfortunately, few physicians feel confident in their ability to apply the principles of genetics and genomics upon which personalized medicine is based to their practice. This book is intended to help the practicing physician understand and apply the principles of genetic and genomic medicine, regardless of his/her level of background in the field. It provides a thorough foundation/review of classical genetic principles, with an emphasis on how these principles apply to personalized medicine and common complex diseases. In addition, it provides a wide-ranging review of the inroads that personalized medicine has made into several fields, including cancer, psychiatric disorders, cardiovascular disease, substance abuse, Alzheimer disease, respiratory diseases, type 2 diabetes and macular degeneration. Most importantly, this book is intended to enable the practicing physician, physician assistants and their entire healthcare team to anticipate the developments that will emerge in the near future, and stay current with the field as it expands.
Название: Towards Personalized Medicine for Cancer ISBN: 1573318159 ISBN-13(EAN): 9781573318150 Издательство: Wiley Рейтинг: Цена: 35640.00 T Наличие на складе: Поставка под заказ. Описание: This volume explores cancer as an individualized problem and addresses the impact of recent advances in cancer biology, genetics, tumor profiling, and medical technology in the personalization of cancer predisposition, diagnosis, prognosis, treatment, and therapy development.
Автор: D. Hunter Best; Jeffrey J. Swensen Название: Molecular Genetics and Personalized Medicine ISBN: 1627039236 ISBN-13(EAN): 9781627039239 Издательство: Springer Рейтинг: Цена: 186340.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book reviews developments in molecular genetics, showing how they have been adopted in clinical practice. The authors simplify complex genetic concepts and focus on patient related issues. The aim is to help shorten the time from lab bench to bedside.
Автор: Debmalya Barh; Dipali Dhawan; Nirmal Kumar Ganguly Название: Omics for Personalized Medicine ISBN: 8132211839 ISBN-13(EAN): 9788132211839 Издательство: Springer Рейтинг: Цена: 243800.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book details how the pharmacogenomics and omics technologies are transforming the medicine and the health care sector for the better. It covers all aspects of pharmacogenomics and its disease-specific applications.
Автор: Stephen T. Sonis, DMD, DMSc Название: Genomics, Personalized Medicine and Oral Disease ISBN: 3319179411 ISBN-13(EAN): 9783319179414 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The objective of this book is to catalyze the application of genomics to the diagnosis and treatment of oral diseases by comprehensively presenting focused discussions on the current state of knowledge. The first section book provides basic information about genetics, genomics and personalized medicine and the informatical methods available to apply and organize genetic data so that it has clinical relevance. Recognizing the genetic robustness of the oral cavity, the introductory section includes chapters on the oral micro biome and host genomics and response to infectious agents. The next two sections contain chapters which describe the genomics of specific oral diseases and conditions, including the genetic basis for mechanism and risk of treatment toxicities associated with cancer therapy and bisphosphonates. Four chapters focus on gene-based therapies and the pharmacogenomics applied to oral disease. The final chapter presents a provocative summary which describes a comprehensive vision of the melding of genomics to personalized medicine and the potential actionable outcomes that will likely affect clinical practice in the upcoming years.
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