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Proteomics for Biomarker Discovery, Virginie Brun; Yohann Cout?


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Автор: Virginie Brun; Yohann Cout?
Название:  Proteomics for Biomarker Discovery
ISBN: 9781493991631
Издательство: Springer
Классификация:


ISBN-10: 1493991639
Обложка/Формат: Hardcover
Страницы: 292
Вес: 0.80 кг.
Дата издания: 2019
Серия: Methods in Molecular Biology
Язык: English
Издание: 1st ed. 2019
Иллюстрации: 49 tables, color; 47 illustrations, color; 5 illustrations, black and white; xii, 292 p. 52 illus., 47 illus. in color.
Размер: 254 x 178 x 19
Читательская аудитория: Professional & vocational
Основная тема: Life Sciences
Подзаголовок: Methods and Protocols
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание: This volume presents modern and enhanced methods that detail techniques to perform proteomics analyses dedicated to biomarker discovery for human health. Chapters guide readers through pre/post analytical factors, protocols for the preparation of extracellular vesicles and exosomes, and various analytical pipelines including Data Independent Acquisition (DIA), discovery, as well as targeted and top-down proteomics analysis workflows. Bioinformatics tools and workflows to select and evaluate candidate biomarkers or combinations of biomarkers are also presented. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Proteomics for Biomarker Discovery: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Дополнительное описание: Pre- and Post-Analytical Factors in Biomarker Discovery.- Pre-Fractionation of Non-Circulating Biological Fluids to Improve Discovery of Clinically Relevant Protein Biomarkers.- Serum Exosome Isolation by Size-Exclusion Chromatography for the Discovery an


Proteomics in Biomarker Identification

Автор: Mohamed A. Selmy
Название: Proteomics in Biomarker Identification
ISBN: 1773610821 ISBN-13(EAN): 9781773610825
Издательство: Mare Nostrum (Eurospan)
Рейтинг:
Цена: 155230.00 T
Наличие на складе: Невозможна поставка.
Описание: Packed with methods and techniques, this book presents a standard operating procedure for sample selection, preparation, and storage, as well as data analysis and modelling. Authoritative and practical, this book will appeal to students of biochemistry, molecular biology and genetics, and all postgraduates and researchers with an interest in genomics and proteomics.

Proteomic and Metabolomic Approaches to Biomarker Discovery,

Автор: Haleem J. Issaq
Название: Proteomic and Metabolomic Approaches to Biomarker Discovery,
ISBN: 0123944465 ISBN-13(EAN): 9780123944467
Издательство: Elsevier Science
Цена: 115940.00 T
Наличие на складе: Невозможна поставка.
Описание: Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. Various techniques are used in the biomarker discovery process, including techniques used in proteomics, the study of the proteins that make up an organism, and metabolomics, the study of chemical fingerprints created from cellular processes. . Proteomic and Metabolomic Approaches to Biomarker Discovery is the only publication that covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods, and presents a standard operating procedure for sample selection, preparation, and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. A vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals, and graduate students, Proteomic and Metabolomic Approaches to Biomarker Discovery provides the information needed to reduce clinical error in the execution of research.

Reviews on Biomarker Studies in Aging and Anti-Aging Research

Автор: Paul C. Guest
Название: Reviews on Biomarker Studies in Aging and Anti-Aging Research
ISBN: 3030256499 ISBN-13(EAN): 9783030256494
Издательство: Springer
Рейтинг:
Цена: 149060.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Using both epidemiological and model organism approaches, we have gained new insights into the physiological and molecular aspects of aging, which has led to significant advancements in potential anti-aging strategies.

Reviews on biomarker studies in psychiatric and neurodegenerative disorders

Название: Reviews on biomarker studies in psychiatric and neurodegenerative disorders
ISBN: 3030055418 ISBN-13(EAN): 9783030055417
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: 1. The Potential of 'Omics to Link Lipid Metabolism and Genetic and Comorbidity Risk Factors of Alzheimer's Disease in African Americans.- 2. The Role of Biomarkers in Alzheimer's Disease Drug Development.- 3. Mitochondrial Involvement in Mental Disorders; Energy Metabolism, Genetic and Environmental Factors.- 4. Lymphocytes, Platelets, Erythrocytes and Exosomes as Possible Biomarkers for Alzheimer's Disease Clinical Diagnosis.- 5. Genetic Risk Factors for Alzheimer Disease: Emerging Roles of Microglia in Disease Pathomechanisms.- 6. Neuroimaging Studies of Cognitive Function in Schizophrenia.- 7. The Role of Biomarkers in Psychiatry.- 8. Interactome Studies of Psychiatric Disorders.- 9. MicroRNAs in Major Depressive Disorder.- 10. Proteomic Markers for Depression.- 11. Advances in Biomarker Studies in Autism Spectrum Disorders.- 12. Proteomic Investigations of Autism Spectrum Disorder: Past Findings, Current Challenges and Future Prospects.- 13. Role of the Gut Microbiome in Autism Spectrum Disorders.- 14. Metabolomic Biomarkers in Mental Disorders: Bipolar Disorder and Schizophrenia.- 15. Early Detection and Treatment of Patients with Alzheimer's Disease: Future Perspectives.

Immunosensing for Detection of Protein Biomarkers

Автор: Huangxian Ju
Название: Immunosensing for Detection of Protein Biomarkers
ISBN: 0081019998 ISBN-13(EAN): 9780081019993
Издательство: Elsevier Science
Рейтинг:
Цена: 179660.00 T
Наличие на складе: Поставка под заказ.
Описание:

Immunosensing for Detection of Protein Biomarkers not only introduces the principles, methods, and classification of immunoassay, but also presents the latest achievements in areas such as electrochemical immunosensors, nanoprobe-based immunoassay, chemiluminescence immunoassay, electrochemiluminescent immunoassay, multianalyte immunoassay, optical imaging for immunoassay, signal amplification for immunoassay, and so on.

In recent years, immunosensing and immunoassay methods have attracted considerable interest due to their applications in different fields, particularly clinical diagnosis. Although a large number of academic papers in immunosensing and immunoassay have been published in different journals recently, it is still a difficult and time-consuming task for researchers, especially those new to the area, to understand the principles, methods, and research progress of immunosensing.

Based on the research experience of the authors and their research groups, this book offers readers with new research ideas to develop immunosensing methodology. As a monograph, it offers deeper and more complete coverage than review papers, which only report certain aspects of progress. Grounded in the research experience of Professor Ju's research group, the book focuses on immunosensing for detection of protein biomarkers, summarizing understanding, research, and practice on immunosensing methodology in detection of protein biomarkers.


Urine Proteomics in Kidney Disease Biomarker Discovery

Автор: Youhe Gao
Название: Urine Proteomics in Kidney Disease Biomarker Discovery
ISBN: 9402407243 ISBN-13(EAN): 9789402407242
Издательство: Springer
Рейтинг:
Цена: 121890.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book systematically summarizes the ideas and technologies used in urine proteome analysis. It argues that change is the core of biomarker definition since the body uses its homeostatic mechanisms to correct changes in the blood. Kidney diseases are emphasized as they produce the most significant changes in urine.

Proteomics for Biomarker Discovery

Автор: Zhou Ming
Название: Proteomics for Biomarker Discovery
ISBN: 1627033599 ISBN-13(EAN): 9781627033596
Издательство: Springer
Рейтинг:
Цена: 111790.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology(t) book details methods used to study proteomics, offering lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Proteomics for Biomarker Discovery

Автор: Ming Zhou; Timothy Veenstra
Название: Proteomics for Biomarker Discovery
ISBN: 1493959999 ISBN-13(EAN): 9781493959990
Издательство: Springer
Рейтинг:
Цена: 111790.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology (TM) book details methods used to study proteomics, offering lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Proteomic And Metabolomic Approaches To Biomarker Discovery

Автор: Issaq, Haleem J.
Название: Proteomic And Metabolomic Approaches To Biomarker Discovery
ISBN: 0128186070 ISBN-13(EAN): 9780128186077
Издательство: Elsevier Science
Рейтинг:
Цена: 151590.00 T
Наличие на складе: Поставка под заказ.
Описание:

Proteomic and Metabolomic Approaches to Biomarker Discovery, Second Edition covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods and presents a standard operating procedure for sample selection, preparation and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process.

This second edition has been fully updated and revised to address recent advances in MS and NMR instrumentation, high-field NMR, proteomics and metabolomics for biomarker validation, clinical assays of biomarkers and clinical MS and NMR, identifying microRNAs and autoantibodies as biomarkers, MRM-MS assay development, top-down MS, glycosylation-based serum biomarkers, cell surface proteins in biomarker discovery, lipodomics for cancer biomarker discovery, and strategies to design studies to identify predictive biomarkers in cancer research.


Reviews on Biomarker Studies of Metabolic and Metabolism-Related Disorders

Автор: Guest Paul C.
Название: Reviews on Biomarker Studies of Metabolic and Metabolism-Related Disorders
ISBN: 3030126676 ISBN-13(EAN): 9783030126674
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book recognizes that throughout the scientific, medical, and economic communities, new tests incorporating biomarkers are needed to improve the diagnosis of patients suffering from metabolic disorders.


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