Late Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of a radical nature, and diverse families of organic compounds, such as (hetero) aromatic rings and aliphatic substrates. Drawing on the author's expert knowledge, this book provides researchers with a broad set of applicable methods to use in their work.
Highlights the latest developments in the field in a concise volume
Provides details of key fluorinating reagents across diverse families of organic compounds
Explores the current applications and future potential of fluorine in drug development
This thesis describes novel substrate embedded physical sensors that can be used to monitor different types of cell-based assays non-invasively and label-free. The sensors described provide integrative information of the cells under study with an adaptable time resolution (ranging from milliseconds to days). This information about the dynamic cell response to chemical, physical or biological stimuli defines a new paradigm in fundamental biomedical research.
The author, Maximilian Oberleitner, describes approaches in which the cells are directly grown on different sensor surfaces (gold-film electrodes, shear wave resonators or dye-doped polymer films). This approach, with the reacting cells in particularly close proximity and contact with the sensor surface, is key to a remarkable sensitivity, opening the way for a variety of new applications. This thesis not only introduces the fundamentals of each approach, but it also describes in great detail the design
principles and elucidates the boundary conditions of the new sensors.
Автор: Li Название: Advances in GaN, GaAs, SiC and Related Alloys on Silicon Substrates ISBN: 1605110388 ISBN-13(EAN): 9781605110387 Издательство: Cambridge Academ Рейтинг: Цена: 65470.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The MRS Symposium Proceeding series is an internationally recognised reference suitable for researchers and practitioners.
Автор: Inamuddin.; Rajender Boddula; Abdullah M Asiri Название: Self-standing Substrates ISBN: 3030295214 ISBN-13(EAN): 9783030295219 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book systematically describes free-standing films and self-supporting nanoarrays growing on rigid and flexible substrates, and discusses the numerous applications in electronics, energy generation and storage in detail.
Автор: Li Название: Advances in GaN, GaAs, SiC and Related Alloys on Silicon Substrates ISBN: 1107408563 ISBN-13(EAN): 9781107408562 Издательство: Cambridge Academ Цена: 28510.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The MRS Symposium Proceeding series is an internationally recognised reference suitable for researchers and practitioners.
Автор: Maximilian Oberleitner Название: Label-free and Multi-parametric Monitoring of Cell-based Assays with Substrate-embedded Sensors ISBN: 3319453831 ISBN-13(EAN): 9783319453835 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Introduction.- Objectives.- Methods & Instrumentation.- MQCM: Multiple Cytomechanic Sensing.- QCM-ECIS: Combined Viscoelastic and Dielectric Sensing of Cells.- QCM-OCS: Optochemical Sensing of Temperature and pO2 in the Cell Surface Junction.- Summary.- Appendix.
Автор: Yavuz Imamogammalu Название: Metathesis Polymerization of Olefins and Polymerization of Alkynes ISBN: 9401061831 ISBN-13(EAN): 9789401061834 Издательство: Springer Рейтинг: Цена: 81050.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of the NATO Advanced Study Institute on Ring-Opening Metathesis Polymerization of Olefins and Polymerization of Alkynes, Akcay-Balikesir, Turkey, 3-16 September 1995
Автор: R.C. Wilhoit; K.N. Marsh; K.N. Marsh; X. Hong; N. Название: Densities of Aliphatic Hydrocarbons: Alkenes, Alkadienes, Alkynes, and Miscellaneous Compounds ISBN: 3540615547 ISBN-13(EAN): 9783540615545 Издательство: Springer Рейтинг: Цена: 1638860.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Data on the densities of organic compounds is essential for both scientific and industrial applications. The tables contain the original literature data, along with their estimated uncertainties, and the evaluated data, in both numerical form and as coefficients to equations with selected statistical information.
Автор: Mark Greenhalgh Название: Iron-Catalysed Hydrofunctionalisation of Alkenes and Alkynes ISBN: 3319336622 ISBN-13(EAN): 9783319336626 Издательство: Springer Рейтинг: Цена: 130610.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Thisthesis gives a thorough account of the development of iron-catalysedhydrosilylation, hydroboration and hydromagnesiation reactions. Withextraordinary referencing and scientific argument, Mark Greenhalgh describesthe development of methodologies which require only commercially availablematerials and non-specialised techniques.
Автор: Simonneau, Antoine Название: Gold-catalyzed cycloisomerization reactions through activation of alkynes ISBN: 3319067060 ISBN-13(EAN): 9783319067063 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Antoine Simonneau`s thesis highlights the development of new cycloisomerization reactions through the activation of alkynes with gold complexes.
Автор: Antoine Simonneau Название: Gold-Catalyzed Cycloisomerization Reactions Through Activation of Alkynes ISBN: 3319360973 ISBN-13(EAN): 9783319360973 Издательство: Springer Рейтинг: Цена: 95770.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Antoine Simonneau`s thesis highlights the development of new cycloisomerization reactions through the activation of alkynes with gold complexes.
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