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The Future of Brain Repair: A Realist`s Guide to Stem Cell Therapy, Price Jack


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Автор: Price Jack
Название:  The Future of Brain Repair: A Realist`s Guide to Stem Cell Therapy
ISBN: 9780262043755
Издательство: MIT Press
Классификация:


ISBN-10: 0262043750
Обложка/Формат: Hardcover
Страницы: 288
Вес: 0.41 кг.
Дата издания: 07.04.2020
Серия: The mit press
Язык: English
Иллюстрации: 10 b 20 illustrations, unspecified; 10 b 20 illustrations, unspecified
Размер: 145 x 210 x 27
Читательская аудитория: General (us: trade)
Подзаголовок: A realist`s guide to stem cell therapy
Ссылка на Издательство: Link
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Поставляется из: США
Описание: A scientist assesses the potential of stem cell therapies for treating such brain disorders as stroke, Alzheimers disease, and Parkinsons disease.

Stem cell therapies are the subject of enormous hype, endowed by the media with almost magical qualities and imagined by the public to bring about miracle cures. Stem cells have the potential to generate new cells of different types, and have been shown to do so in certain cases. Could stem cell transplants repair the damaged brain? In this book, neurobiologist Jack Price assesses the potential of stem cell therapies to treat such brain disorders as stroke, Alzheimers disease, Parkinsons disease, and spinal cord injuries.

Certainly brain disorders are in need of effective treatments. These disorders dont just kill, they disable, and conventional drug therapies have not had much success in treating them. Price explains that repairing the human brain is difficult, largely because of its structural, functional, and developmental complexity. He examines the self-repairing capacity of blood and gut cells--and the lack of such capacity in the brain; describes the limitations of early brain stem cell therapies for neurodegenerative disorders; and discusses current clinical trials that may lead to the first licensed stem cell therapies for stroke, Parkinsons and macular degeneration. And he describes the real promise of pluripotential stem cells, which can make all the cell types that constitute the body.

New technologies, Price reports, challenge the very notion of cell transplantation, instead seeking to convince the brain itself to manufacture the new cells it needs. Could this be the true future of brain repair?



Cell Therapy for Perinatal Brain Injury

Автор: Shintaku
Название: Cell Therapy for Perinatal Brain Injury
ISBN: 9811014116 ISBN-13(EAN): 9789811014116
Издательство: Springer
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Цена: 125770.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a wealth of insights, advances and new perspectives on cell therapy for different types of neonatal ischemic disease, such as Hypoxic-Ischemic Encephalopathy (HIE), Periventricular Leukomalacia (PVL) and neonatal infarction. These diseases pose serious challenges for neonatologists and neurologists, because the severe sequelae lead to decreasing QOL for patients and their families. Accordingly, new treatments for neonatal ischemic diseases are needed all over the world. The book develops new effective therapies combined with hypothermia therapy, an established treatment for HIE. After reviewing past approaches, it presents cutting-edge topics in cell therapy, one of the most promising candidates for treating neonatal ischemic disease. Cell Therapy for Neonatal Ischemic Diseasewill offer readers a better understanding of the current state of the art in this field from bench to bedside, and inspire researchers and physicians to further explore this evolving therapy.

Advances in Stem Cell Therapy

Автор: El-Badri
Название: Advances in Stem Cell Therapy
ISBN: 3319291475 ISBN-13(EAN): 9783319291475
Издательство: Springer
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Цена: 139750.00 T
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Описание: The book reviews the main approaches for generation of differentiated cells from various types of stem cells, including embryonic, placental and cord blood stem cells through marrow, adipose tissue and dental pulp. The book starts with an overview of experimental protocols applied to generate insulin secreting cells, neural cells, heart cells, and other tissue specific cells ex vivo and in experimental animals. This is followed by exhaustive review of clinical trials in these pathologies. It continues with a comparison of the merits of successful transplantation in humans versus animal experimentation, and highlights the most promising clinical applications in the field. Special chapters are devoted to the topic of tissue engineering and modern synthetic and biological scaffolds. It is essential reading for scientists and researchers in tissue engineering and stem cell research as well as clinicians who are involved in developing or testing stem cell therapies.

Cell Therapy for Brain Repair.2006

Автор: Paul
Название: Cell Therapy for Brain Repair.2006
ISBN: 1588295028 ISBN-13(EAN): 9781588295026
Издательство: Springer
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Цена: 217680.00 T
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Описание: Cell Therapy, Stem Cells, and Brain Repair reviews the most compelling treatments for neurodegenerative diseases, disorders, and injuries, including Parkinson's disease, Huntington's disease, traumatic brain injury, and stroke. Covering the history of cell therapy and neural transplantation, it also focuses on stem cells, including embryonic, bone marrow, and umbilical cord blood, as well as other investigative sources. This compilation explicates previous cornerstones and milestones of neurological cellular therapy, which have provided a foundation for modern stem cell research. In Cell Therapy, Stem Cells, and Brain Repair, the challenges and current direction of cellular research are described in great detail. Modern techniques involving certain subsets of cell populations are also explained. In addition, the ongoing discovery of stem cell sources for cell therapy is discussed, while expounding upon clinical applications for cellular therapeutic brain repair as certain cells become increasingly promising. Explaining the field of cell therapy from a scientific, clinical, and ethical perspective, Cell Therapy, Stem Cell, and Brain Repair is essential reading for neurologists, scientists, and clinicians looking to stay on the cutting-edge of regenerative medicine.

Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair

Автор: Nabil Dib; Doris A. Taylor; Edward B. Diethrich
Название: Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair
ISBN: 1489985646 ISBN-13(EAN): 9781489985644
Издательство: Springer
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Цена: 156720.00 T
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Описание: Myocardial Remodeling.- Ventricular Remodeling In Ischemic Cardiomyopathy.- Myocardial Regeneration.- Myocardial Regeneration: Which Cell and Why.- Cardiac Stem Cells.- Cardiac Stem Cells for Myocardial Regeneration.- Skeletal Myoblast.- A Historic Recapitulation of Myoblast Transplantation.- Myoblast Cell Transplantation: Preclinical Studies.- Skeletal Myoblasts: The European Experience.- Skeletal Myoblasts: The U.S. Experience.- Progenitor Cells.- Progenitor Cells for Cardiac Regeneration.- Bone Marrow.- Bone Marrow-Derived Stem Cell for Myocardial Regeneration: Preclinical Experience.- Bone Marrow Derived Stem Cells for Myocardial Regeneration: Clinical Experience, Surgical Delivery.- Autologous Mononuclear Bone Marrow Cell Transplantion for Myocardial Infarction: The German Experience.- Autologous Mononuclear Bone Marrow Transplantation for Myocardial Infarction: The Spanish Experience.- Mobilizing Bone Marrow Stem Cells for Myocardial Repair After Acute Myocardial Infarction.- Percutaneous Stem Cell Transplantation.- Percutaneous Myoblast Transplantation: Steps In Translational Research.- A Porcine Model of Myocardial Infarction for Evaluation of Cell Transplantation.- Tissue Engineering.- Tissue Engineering for Myocardial Regeneration.- Functional and Electrophysiological Assessment after Cell Tranplantation.- The Role of Pet Scan in Stem Cell Therapy.- The Measurement of Systolic Function in the Mammalian Heart.- Electrophysiological Aspects of Cell Transplantation.- Regulatory Perspective.- Regulatory Considerations in Manufacturing, Product Testing, and Preclinical Development of Cellular Products for Cardiac Repair.

Cell Therapy for Brain Injury

Автор: David C. Hess
Название: Cell Therapy for Brain Injury
ISBN: 3319150626 ISBN-13(EAN): 9783319150628
Издательство: Springer
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Цена: 149060.00 T
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Описание: Cell Therapy for Brain Injury is a thorough examination of using state-of-the-art cell therapy in the treatment of strokes and other traumatic brain injuries. This invaluable book covers this niche topic in depth from basic stem cell biology and principles of cell therapy through proposed mechanisms of action of cell therapy in stroke, pre-clinical data in stroke models, ongoing clinical trials, imaging and tracking of cells with MRI, neural stem cells in stroke and the "big pharma" perspective of cell therapy. Each chapter is written by well-known leaders in each field, thus providing a wealth of expertise.

The breadth of this book makes it essential reading for neuroscientists, stem cell biologists, researchers or clinical trialists at pharmaceutical or biotechnology companies. It also serves as a thorough introduction for graduate students or post-doctoral fellows who hope to work in these fields.


Cell Therapy for Brain Injury

Автор: David C. Hess
Название: Cell Therapy for Brain Injury
ISBN: 3319380990 ISBN-13(EAN): 9783319380995
Издательство: Springer
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Цена: 121890.00 T
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Описание:

Introduction to Cell Therapy in Brain Injury.- Cell Based Therapeutics in Stroke: An Industry Perspective.- Autologous Mesenchymal Stem Cell Therapy in Patients with Stroke.- Treatment of Autologous Bone Marrow Mononuclear Cells for Acute and Subacute Stroke: Cell-Therapy for Acute/Subacute Stroke.- Clinical Development of MultiStem(R) for Treatment of Injuries and Diseases of the Central Nervous System.- Intra-Arterial Approaches to Stem Cell Therapy for Ischemic Stroke.- Neural Stem Cells in Stroke: Intracerebral Approaches.- The CTX Human Neural Stem Cell Line and the PISCES Stroke Trial.- Induced Pluripotent Stem Cells as a Cell-based Therapeutic in Stroke.- Induced Pluripotent Stem Cell Derived Neural Cell Types In Treatment of Stroke.- Preconditioning and Cell-based Therapeutics.- Tracking of Administered Progenitor Cells in Brain Injury and Stroke by Magnetic Resonance Imaging.- Biomaterials Application in Stem Cell Therapies for Stroke.- A Stem Cell Derived Cell-Free Therapy for Stroke: Moving Conditioned Medium into Clinical Trial.- Pathophysiology of Traumatic Brain Injury: Rationale and Role for Cellular Therapies.- Stem Cell Therapy for Neonatal Hypoxic-Ischemic Brain Injury.- Cell-Based Therapies in Neonatal Stroke.- Issues in Clinical Trial Design in Stem Cell Trials after Stroke.


Cell Therapy for Perinatal Brain Injury

Автор: Shintaku
Название: Cell Therapy for Perinatal Brain Injury
ISBN: 9811338205 ISBN-13(EAN): 9789811338205
Издательство: Springer
Рейтинг:
Цена: 125770.00 T
Наличие на складе: Невозможна поставка.
Описание: This book provides a wealth of insights, advances and new perspectives on cell therapy for different types of neonatal ischemic disease, such as Hypoxic-Ischemic Encephalopathy (HIE), Periventricular Leukomalacia (PVL) and neonatal infarction.

Bone marrow stem cell therapy for stroke

Автор: Kunlin Jin; Xunming Ji; Qichuan Zhuge
Название: Bone marrow stem cell therapy for stroke
ISBN: 9811097410 ISBN-13(EAN): 9789811097416
Издательство: Springer
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Цена: 149060.00 T
Наличие на складе: Поставка под заказ.
Описание: This book covers recent advances in all aspects of bone marrow-derived stem cells (BMSCs) for stroke treatment, while also providing comprehensive information on human clinical trials and animal models of stroke.

Cell Biology and Translational Medicine, Volume 5: Stem Cells: Translational Science to Therapy

Автор: Turksen Kursad
Название: Cell Biology and Translational Medicine, Volume 5: Stem Cells: Translational Science to Therapy
ISBN: 303017591X ISBN-13(EAN): 9783030175917
Издательство: Springer
Рейтинг:
Цена: 93160.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

Benjamin W. Streeter, Michael E. Davis Therapeutic Cardiac Patches for Repairing the Myocardium

Nidheesh Dadheech and AM James Shapiro Human Induced Pluripotent Stem Cells in the Curative Treatment of Diabetes and Potential Impediments Ahead

Selami Demirci, PhD, Alexis Leonard, MD, Juan J. Haro-Mora, PhD, Naoya Uchida, MD, PhD and John F Tisdale, MD CRISPR/Cas9 for Sickle Cell Disease: Applications, Future possibilities, and Challenges

David Richards, Joe Swift, Lu Shin Wong, Stephen M. Richardson; Photoresponsive Hydrogels with Photoswitchable Stiffness: Emerging Platforms to Study Temporal Aspects of Mesenchymal Stem Cell Responses to Extracellular Stiffness Regulation

Isabel Calejo, Raquel Costa-Almeida, Manuela E. Gomes; Cellular complexity at the interface: Challenges in enthesis tissue engineering

BURCU TALUG AND ZEYNEP TOKCAER KESKIN; Induced Pluripotent Stem Cells in Disease Modelling and Regeneration

Ayşegьl Mendi, Hacer Ulutьrk, Mustafa Sancar Ataз, Derviş Yılmaz; Stem cells for the oromaxillofacial area: Could they be a promising source for regeneration in dentistry?

Safa AYDIN, Fikrettin ŞAHİN; Stem Cells Derived from Dental Tissues

Hьseyin Abdik, Ezgi Avsar Abdik, Ayşen Aslı Hızlı Deniz, Pakize Neslihan Taşlı, Fikrettin Şahin; A Novel Virtue in Stem Cell Research: Exosomes and Their Role in Differentiation

Taha Bartu Hayal, Binnur Kıratlı, Hatice Burcu Şişli, Fikrettin Şahin, Ayşegьl Doğan; Mesenchymal Stem Cells as Regulators of Carcinogenesis


Stem Cell-Based Therapy for Lung Disease

Автор: Burgess
Название: Stem Cell-Based Therapy for Lung Disease
ISBN: 3030294021 ISBN-13(EAN): 9783030294021
Издательство: Springer
Рейтинг:
Цена: 83850.00 T
Наличие на складе: Поставка под заказ.
Описание: This book presents state-of-the-art pre-clinical models and clinical applications of stem-cell-based therapies applied to different lung diseases, with a special focus on the translation of bench data into clinical studies. Starting with the assumption that abnormal lung tissue repair and regeneration has emerged as the driving force underlying pathogenesis and progression in many lung diseases, it sheds new light on the potential of stem/stromal cells as drivers of repair and sources of reparative factors in the lung. The first part of the book offers an overview of stem cell types and mechanisms involved in lung development, homeostasis, repair and regeneration, and reveals the crucial role of the extracellular matrix within the lung microenvironment. In the second part, leading experts present the latest pre-clinical evidence and clinical applications of stem-cell-based therapies in a wide variety of lung diseases, ranging from COPD and lung fibrosis to other rare lung diseases. The last section discusses stem cell delivery systems and devices, such as aerosolised spray application. This book appeals to pneumologists, stem cell and matrix biologists, as well as bioengeneers with a special interest in regenerative medicine applied to pulmonary diseases.

Stem Cell-Based Therapy for Neurodegenerative Diseases

Автор: Han Fabin, Lu Pengzhe (Paul)
Название: Stem Cell-Based Therapy for Neurodegenerative Diseases
ISBN: 9811543690 ISBN-13(EAN): 9789811543692
Издательство: Springer
Цена: 93160.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book reviews the state-of-the-art in stem-cell-based therapies for neurodegenerative diseases, and highlights advances in both animal models and clinical trials.

Animal Models for Stem Cell Therapy

Автор: Bruno Christ; Jana Oerlecke; Peggy Stock
Название: Animal Models for Stem Cell Therapy
ISBN: 149394813X ISBN-13(EAN): 9781493948130
Издательство: Springer
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Цена: 111790.00 T
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Описание: In Animal Models for Stem Cell Therapy: Methods and Protocols, expert researchers in the field detail disease models of hepatic, cardiovascular, neurological diseases, connective and contractile tissue. Chapters focus on a wide range of diseases and application of different kinds of stem cells and reprogrammed tissue cells (iPS). Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Animal Models for Stem Cell Therapy: Methods and Protocols, covers interest of basic scientists and clinicians to assess the biological as well as the therapeutic potential of stem cell therapy.


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