Автор: Ahuja Ravindra K., Magnanti Thomas L. Название: Network Flows ISBN: 0343248603 ISBN-13(EAN): 9780343248604 Издательство: Неизвестно Рейтинг: Цена: 26130.00 T Наличие на складе: Невозможна поставка.
Protein tyrosine phosphatases remove phosphates from the phosphotyrosine residues of target proteins and reverse the action of various protein tyrosine kinases. This essential interplay between the opposing actions of protein tyrosine phosphatases and protein tyrosine kinases forms the basis of signaling networks that underlie the cellular workings of human physiology. Initially passed-off as housekeeping genes; these proteins were only acknowledged to maintain a steady background of phosphotyrosine levels in the cell. However, recent progress in studying their role in embryonic development and human disease has established their importance as regulators of signal regulation. Convincing evidence shows the role of mutations in these proteins to cause and/or intensify the severity of various diseases including metabolic and neurological disorders and also cancer. Protein tyrosine phosphatases have slowly, yet convincingly become crucial targets for therapeutic intervention of various human pathophysiologies.
This book describes these signaling enzymes using the molecular details of their structure and mechanistic function. Various subtypes of cysteine-based Class I, II, III and the Haloacid dehalogenase related Class IV protein tyrosine phosphatases have been illustrated and explained. The superfamily of proteins is also described vis-a-vis its complimentary protein phosphoserine/phosphoserine phosphatases. Membrane bound receptor forms and the cytosolic non-receptor protein tyrosine phosphatases have been described for their biological function. This book serves as a reference for any reader looking to understand the sequence features, structural elements, molecular mechanism and cellular function of this superfamily of signaling enzymes.
Автор: Ahuja Nita, Coleman Joann Название: Johns Hopkins Patients` Guide to Pancreatic Cancer ISBN: 0763774588 ISBN-13(EAN): 9780763774585 Издательство: Jones & Bartlett Рейтинг: Цена: 30040.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The Johns Hopkins Patients' Guide to Pancreatic Cancer is a concise, easy-to-follow "how to" guide that puts you on a path to wellness by explaining pancreatic cancer treatments from start to finish. It guides you through the overwhelming maze of treatment decisions, simplifies the complicated schedule that lies ahead, and provides valuable tools to help you to put together your plan of care. Empower yourself with accurate, understandable information that will give you the ability to confidently participate in the decision making about your care and treatment. About the Series: Learning that you or someone you love has cancer is devastating, and feeling lost and powerless is a common immediate response. The Johns Hopkins Patients' Guides are designed to alleviate your anxiety, empower you with information, and enable you to fully understand your treatment options. Each book in this series is dedicated to a specific type of cancer. The information is there to help lighten your burden and to assist you in becoming an active participant in your care. Cancer rarely allows us to take a diversion from life, and offering guidance on how to continue to live life while working hard on getting well is part of the outcome we hope to help you achieve.
Автор: Astha Ahuja Название: Micro, Small and Medium Enterprises (MSMEs) in Post-COVID-19 Era ISBN: 8177085131 ISBN-13(EAN): 9788177085136 Издательство: Gazelle Book Services Рейтинг: Цена: 117250.00 T Наличие на складе: Поставка под заказ. Описание: As per the Annual Report, 2018-19 of the Ministry of Micro, Small and Medium Enterprises, Government of India, there were 633.88 lakh micro, small and medium enterprises (MSMEs) in the country engaged in different economic activities. Total employment in the MSMEs sector is estimated to be 1,109 lakh, and their contribution to gross domestic product (GDP) is pegged at 28.9 percent. In the wake of COVID-19, it was a particularly challenging time for MSMEs, many of which were on the brink of closing down their operations. Sensing the gravity of the situation, Prime Minister Narendra Modi announced on May 12, 2020, the Aatmanirbhar Bharat Abhiyan (Self-reliant India Initiative) which combined relief, policy reforms and fiscal and monetary measures to help businesses and individuals cope up with the situation created by COVID-19 pandemic. A mega package of ` 20 lakh crore (10 percent of the GDP) was announced for the purpose. The details of the ` 20 lakh crore package were announced by Finance Minister Nirmala Sitharaman in five tranches during the next five consecutive days. All the measures were aimed at spurring investment and buffering the economy against the Covid pandemic shock. In a bid to make MSMEs sector of the economy survive, the Finance Minister in her first tranche of the stimulus, announced on May 13, 2020, laid out specific boosters that could offer some relief to this hard-hit sector. The nearly ` 6 lakh crore tranche, included ` 3 lakh crore collateral-free automatic loans for MSMEs. Furthermore, from July 1, 2020, a new classification of MSMEs with liberalized definitions is in place. This book provides a descriptive and analytical account of the functioning of MSMEs in India. It discusses at length their role in the Indian economy, policies and programmes of the Government to promote them, and the problems faced by them.
Автор: Ahuja M. R., Jain S. Mohan Название: Genetic Diversity and Erosion in Plants: Case Histories ISBN: 3319798634 ISBN-13(EAN): 9783319798639 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Genetic erosion is the loss of genetic diversity within a species. It can happen very quickly, due to catastrophic events, or changes in land use leading to habitat loss. But it can also occur more gradually and remain unnoticed for a long time. One of the main causes of genetic erosion is the replacement of local varieties by modern varieties. Other causes include environmental degradation, urbanization, and land clearing through deforestation and brush fires. In order to conserve biodiversity in plants, it is important to targets three independent levels that include ecosystems, species and genes. Genetic diversity is important to a species’ fitness, long-term viability, and ability to adapt to changing environmental conditions. Chapters in this book are written by leading geneticists, molecular biologists and other specialists on relevant topics on genetic erosion and conservation genetic diversity in plants. This divisible set of two volumes deals with a broad spectrum of topics on genetic erosion, and approaches to biodiversity conservation in crop plants and trees. Volume 1 deals with indicators and prevention of genetic erosion, while volume 2 covers genetic diversity and erosion in a number of plants species. These two volumes will also be useful to botanists, biotechnologists, environmentalists, policy makers, conservationists, and NGOs working to manage genetic erosion and biodiversity.
This book series is interested in tracing at the example of work the historical connections between regions and in critically engaging with the idea of the North Atlantic World as „normal“ and the rest as „exceptional“ and „in need of explanation“. Books to be published in the series should address the history of commodified labor and investigate one or more of its many forms on a global scale: wage labor, but also serfdom and slavery, self-employed, domestic and “reproductive” labor and the various forms of subsistence and cooperative labor - paid and unpaid work beyond wage labor that constantly has been made invisible. These various labor forms need to be studied both in their specifities and as elements in a linked history of labor. The history and current situation of Africa offer rich examples for. If one of the virtues of labor history in recent decades has been its microhistorical focus on workers and work in relation to the range of social processes in a particular milieu, this series mainly attempts to look beyond both locality and region toward wider spatial relationships. The aim is to publish studies that change focus back and forth from the intimacy and complexity of relationships in specific places and their connections to distant places and long-term processes of change.
Advisory Board:
• Marcel van der Linden (International Institute of Social History, Amsterdam)
• Sandrine Kott (University of Geneva)
• Ravi Ahuja (University of Gottingen)
• Susan Zimmermann (Central European University Budapest)
• Prabhu Mohapatra (University of Delhi)
• Marsha Siefert (Central European University Budapest)
Imagine if people around you had x-ray vision that could capture your inner experience. In your most stressful moments as a physician, what would they see?
As a medical doctor, every treatment prescribed or surgery performed carries high stakes for each patient. It can impact their quality of life in significant ways, or literally mean life or death. But the culture of silence in medicine makes it difficult to talk about the unique responsibilities and stresses associated with being a physician.
Stress in Medicine challenges this culture of silence.
In this remarkably honest and inspiring book, Dr. Nina Ahuja offers a unique glimpse into the world of medicine, sharing personal stories from her own journey that are heartfelt and touching, and at times laugh-out-loud funny.
Woven throughout her experiences and observations, Dr. Ahuja's innovative approach to mental and emotional clarity shines through-a practical approach that can lower the stress level of any situation and sharpen your mind when you need it most.
Автор: Ahuja Nandini Название: It`s Big Brother Time! ISBN: 0062884379 ISBN-13(EAN): 9780062884374 Издательство: HarperCollins USA Рейтинг: Цена: 5570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Good thing it`s big brother time-he can show Baby how to be the best baby ever!Told through the eyes of a big brother, this charming hardcover picture book empowers older siblings by showing them that they have very important roles to play in introducing their family`s new baby to the world.
Автор: Ahuja Nandini Название: Rise Up and Write It: With Real Mail, Posters, and More! ISBN: 0063029596 ISBN-13(EAN): 9780063029590 Издательство: HarperCollins USA Рейтинг: Цена: 11430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Ticket to Ride First Journey, a family-friendly introduction to the Ticket to Ride series. The game features a board of Europe, with shorter routes and new whimsical illustrations in every city. With this simpler version of Ticket to Ride, younger players and beginners alike can take their first steps in the train game series.Although rules are simplified and game objectives made easier, the game remains faithful to what has made Ticket to Ride a success: players race to complete their tickets by capturing routes on the board. The imaginative art on the board and on the ticket cards makes it easy to find cities for even the youngest players, who will be delighted to build their own networks with the big plastic train pieces included in the game.A European map for younger players was the logical next step of the Ticket to Ride series says Alan R. Moon, the game designer. The Europe version of Ticket to Ride is a bestseller in Europe, kids will now have their own version on which they could challenge their parents.Ticket to Ride First Journey is a stand-alone game for 2 to 4 players ages 6 and older, which takes approximately 15-30 minutes to play. It includes 1 Map of Europe, 80 Custom Plastic Trains (20 per player), 72 Train Cards, 32 Ticket Cards, East-to-West Bonus Cards and 1 Golden Ticket.
Автор: Ahuja Masuma Название: Girlhood: Teens Around the World in Their Own Voices ISBN: 1643750119 ISBN-13(EAN): 9781643750118 Издательство: Неизвестно Рейтинг: Цена: 14770.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Thirty girls in twenty-seven countries share diary entries and photographs in this celebration of the day-to-day lives of ordinary girls around the world.
Автор: Ravi Ahuja, Martin Christof-Fuchsle Название: A Great War in South India: German Accounts of the Anglo-Mysore Wars, 1766-1799 ISBN: 3110640546 ISBN-13(EAN): 9783110640540 Издательство: Walter de Gruyter Цена: 111510.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book examines documents from the wars between the British colonial power and the South Indian regional power Mysore between 1766 and 1799. It transcribes and makes available for the first time the rich German documentation of a war that was as destructive as the Thirty Years War in Germany.
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