Advances in Structure of Membrane Proteins, Aleksei Anatoliyovych Stepanenko

Автор: Wolfgang B. Fischer
Название: Viral Membrane Proteins: Structure, Function, and Drug Design
ISBN: 1441934537 ISBN-13(EAN): 9781441934536
Издательство: Springer
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Цена: 186330.00 T
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Описание: The range of information covered includes signal proteins, ion channels, and fusion proteins.This book has a place in the libraries of researchers and scientists in a wide array of fields, including protein chemistry, molecular biophysics, pharmaceutical science and research, bioanotechnology, molecular biology, and biochemistry.

Автор: Separovic Frances, Naito Akira
Название: Advances in Biological Solid-State NMR: Proteins and Membrane-Active Peptides
ISBN: 1849739102 ISBN-13(EAN): 9781849739108
Издательство: Royal Society of Chemistry
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Цена: 246400.00 T
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Описание: Advances in Biological NMR brings the reader up to date with chapters from international leaders of this growing field, covering the most recent developments in the methodology and applications of solid state NMR to studies of membrane interactions and molecular motions.

Автор: Domene Carmen
Название: Computational Biophysics of Membrane Proteins
ISBN: 1782624902 ISBN-13(EAN): 9781782624905
Издательство: Royal Society of Chemistry
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Цена: 252030.00 T
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Описание: Exploring current themes in modern computational and membrane protein biophysics, this book is ideal for researchers in computational chemistry and computational biophysics.

Автор: David Whitford
Название: Proteins: Structure and Function
ISBN: 0471498947 ISBN-13(EAN): 9780471498940
Издательство: Wiley
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Цена: 56970.00 T
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Описание: * An accessible introduction to the principles of protein structure and function. * Beautifully illustrated throughout in full colour. * Includes end of chapter problems, references to further reading and a full glossary of terms. * Associated website including web-based tutorials, problems and additional content. .

Автор: Chung S.H., Andersen O.S., Krishnamurthy V.
Название: Biological Membrane Ion Channels / Dynamics, Structure, and Applications
ISBN: 0387333231 ISBN-13(EAN): 9780387333236
Издательство: Springer
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Цена: 204040.00 T
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Описание: Deals with breakthroughs in ion-channel research that have been brought about by joint efforts of experimental biophysicists and computational physicists, who together are beginning to unravel the story of these designed biomolecules. This book is aimed at researchers in nanodevices and biosensors, undergraduate and graduate students in biology.

Автор: Richardson
Название: Recent Advances in Transthyretin Evolution, Structure and Biological Functions
ISBN: 3642006450 ISBN-13(EAN): 9783642006456
Издательство: Springer
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Цена: 231990.00 T
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Описание: There is a strong interest in transthyretin in connection with protein evolution, medical and clinical research. Transthyretin is a protein found in human blood and cerebrospinal fluid. It is directly involved in the transport of thyroid hormones, and indirectly in that of retinol. This monograph presents various developments and discoveries.

Автор: Moraes
Название: The Next Generation in Membrane Protein Structure Determination
ISBN: 3319350706 ISBN-13(EAN): 9783319350707
Издательство: Springer
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Цена: 139750.00 T
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Описание: This book reviews current techniques used in membrane protein structural biology, with a strong focus on practical issues. The study of membrane protein structures not only provides a basic understanding of life at the molecular level but also helps in the rational and targeted design of new drugs with reduced side effects. Today, about 60% of the commercially available drugs target membrane proteins and it is estimated that nearly 30% of proteins encoded in the human genome are membrane proteins. In recent years much effort has been put towards innovative developments to overcome the numerous obstacles associated with the structure determination of membrane proteins. This book reviews a variety of recent techniques that are essential to any modern researcher in the field of membrane protein structural biology. The topics that are discussed are not commonly found in textbooks. The scope of this book includes: * Expression screening using fluorescent proteins * The use of detergents in membrane protein research * The use of NMR * Synchrotron developments in membrane protein structural biology * Visualisation and X-ray data collection of microcrystals * X-ray diffraction data analysis from multiple crystals * Serial millisecond crystallography * Serial femtosecond crystallography * Membrane protein structures in drug discovery The information provided in this book should be of interest to anyone working in the area of structural biology. Students will find carefully prepared overviews of basic ideas and advanced protein scientists will find the level of detail required to apply the material directly to their day to day work. Chapters 4, 5, 6, 8 and 9 of this book are published open access under a CC BY 4.0 license at link.springer.com.

Автор: Jean-Jacques Lacapere
Название: Membrane Protein Structure and Function Characterization
ISBN: 1493971492 ISBN-13(EAN): 9781493971497
Издательство: Springer
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Цена: 130430.00 T
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Описание: In this present volume, different approaches are detailed to produce membrane proteins, purify them, study their function, determine their structure, and model them in membrane.

Автор: Samantha J. Richardson; Vivian Cody
Название: Recent Advances in Transthyretin Evolution, Structure and Biological Functions
ISBN: 3642420710 ISBN-13(EAN): 9783642420719
Издательство: Springer
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Цена: 204970.00 T
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Описание: Since its ?rst description in 1942 in both serum and cerebrospinal ?uid, transthyretin (TTR) has had an eventful history, including changes in name from “prealbumin” to “thyroxine-binding prealbumin” to “transthyretin” as knowledge increased about its functions. TTR is synthesised in a wide range of tissues in humans and other eutherian mammals: the liver, choroid plexus (blood- cerebrospinal ?uid barrier), retinal pigment epithelium of the eye, pancreas, intestine and meninges. However, its sites of synthesis are more restricted in other vertebrates. This implies that the number of tissues synthesising TTR during vertebrate evolution has increased, and raises questions about the selection pressures governing TTR synthesis. TTR is most widely known as a distributor of thyroid hormones. In addition, TTR binds retinol-binding protein, which binds retinol. In this way, TTR is also involved with retinoid distribution. More recently, TTR has been demonstrated to bind a wide variety of endocrine disruptors including drugs, pollutants, industrial compounds, heavy metals, and some naturally occurring plant ?avonoids. These not only interfere with thyroid hormone delivery in the body, but also transport such endocrine disruptors into the brain, where they have the potential to accumulate.